Complet list of 2bid hssp file
Complete list of 2bid.hssp file
HSSP HOMOLOGY DERIVED SECONDARY STRUCTURE OF PROTEINS , VERSION 2.0 2011
PDBID 2BID
THRESHOLD according to: t(L)=(290.15 * L ** -0.562) + 5
REFERENCE Sander C., Schneider R. : Database of homology-derived protein structures. Proteins, 9:56-68 (1991).
CONTACT Maintained at http://www.cmbi.ru.nl/ by Maarten L. Hekkelman
DATE file generated on 2014-05-17
HEADER APOPTOSIS 27-JAN-99 2BID
COMPND MOL_ID: 1; MOLECULE: PROTEIN (BID); CHAIN: A; ENGINEERED: YES; OTHER_D
SOURCE MOL_ID: 1; ORGANISM_SCIENTIFIC: HOMO SAPIENS; ORGANISM_COMMON: HUMAN;
AUTHOR J.J.CHOU,H.LI,G.S.SALVESEN,J.YUAN,G.WAGNER
DBREF 2BID A 3 197 UNP P55957 BID_HUMAN 1 195
SEQLENGTH 197
NCHAIN 1 chain(s) in 2BID data set
NALIGN 54
NOTATION : ID: EMBL/SWISSPROT identifier of the aligned (homologous) protein
NOTATION : STRID: if the 3-D structure of the aligned protein is known, then STRID is the Protein Data Bank identifier as taken
NOTATION : from the database reference or DR-line of the EMBL/SWISSPROT entry
NOTATION : %IDE: percentage of residue identity of the alignment
NOTATION : %SIM (%WSIM): (weighted) similarity of the alignment
NOTATION : IFIR/ILAS: first and last residue of the alignment in the test sequence
NOTATION : JFIR/JLAS: first and last residue of the alignment in the alignend protein
NOTATION : LALI: length of the alignment excluding insertions and deletions
NOTATION : NGAP: number of insertions and deletions in the alignment
NOTATION : LGAP: total length of all insertions and deletions
NOTATION : LSEQ2: length of the entire sequence of the aligned protein
NOTATION : ACCNUM: SwissProt accession number
NOTATION : PROTEIN: one-line description of aligned protein
NOTATION : SeqNo,PDBNo,AA,STRUCTURE,BP1,BP2,ACC: sequential and PDB residue numbers, amino acid (lower case = Cys), secondary
NOTATION : structure, bridge partners, solvent exposure as in DSSP (Kabsch and Sander, Biopolymers 22, 2577-2637(1983)
NOTATION : VAR: sequence variability on a scale of 0-100 as derived from the NALIGN alignments
NOTATION : pair of lower case characters (AvaK) in the alignend sequence bracket a point of insertion in this sequence
NOTATION : dots (....) in the alignend sequence indicate points of deletion in this sequence
NOTATION : SEQUENCE PROFILE: relative frequency of an amino acid type at each position. Asx and Glx are in their
NOTATION : acid/amide form in proportion to their database frequencies
NOTATION : NOCC: number of aligned sequences spanning this position (including the test sequence)
NOTATION : NDEL: number of sequences with a deletion in the test protein at this position
NOTATION : NINS: number of sequences with an insertion in the test protein at this position
NOTATION : ENTROPY: entropy measure of sequence variability at this position
NOTATION : RELENT: relative entropy, i.e. entropy normalized to the range 0-100
NOTATION : WEIGHT: conservation weight
## PROTEINS : identifier and alignment statistics
NR. ID STRID %IDE %WSIM IFIR ILAS JFIR JLAS LALI NGAP LGAP LSEQ2 ACCNUM PROTEIN
1 : A8ASI8_HUMAN 1.00 1.00 3 197 1 195 195 0 0 195 A8ASI8 BH3 interacting domain death agonist, isoform CRA_d OS=Homo sapiens GN=BID PE=2 SV=1
2 : BID_HUMAN 2M5B 1.00 1.00 3 197 1 195 195 0 0 195 P55957 BH3-interacting domain death agonist OS=Homo sapiens GN=BID PE=1 SV=1
3 : B3KT21_HUMAN 0.99 1.00 2 197 46 241 196 0 0 241 B3KT21 cDNA FLJ37476 fis, clone BRAWH2012827, highly similar to Homo sapiens BH3 interacting domain death agonist (BID), transcript variant 1, mRNA OS=Homo sapiens PE=2 SV=1
4 : G3R4T6_GORGO 0.99 1.00 2 197 46 241 196 0 0 241 G3R4T6 Uncharacterized protein OS=Gorilla gorilla gorilla GN=101142032 PE=4 SV=1
5 : H2QL73_PANTR 0.99 1.00 2 197 46 241 196 0 0 241 H2QL73 Uncharacterized protein OS=Pan troglodytes GN=BID PE=4 SV=1
6 : G1R8L1_NOMLE 0.98 0.99 3 197 1 195 195 0 0 195 G1R8L1 Uncharacterized protein OS=Nomascus leucogenys GN=BID PE=4 SV=2
7 : G7N375_MACMU 0.93 0.99 2 194 35 227 193 0 0 227 G7N375 p22 BID (Fragment) OS=Macaca mulatta GN=EGK_02769 PE=4 SV=1
8 : G7PH70_MACFA 0.93 0.99 2 194 42 234 193 0 0 234 G7PH70 p22 BID (Fragment) OS=Macaca fascicularis GN=EGM_02421 PE=4 SV=1
9 : F7IH59_CALJA 0.80 0.91 2 197 43 235 197 2 5 235 F7IH59 Uncharacterized protein OS=Callithrix jacchus GN=BID PE=4 SV=1
10 : E2IV87_9PRIM 0.78 0.90 28 179 1 149 153 2 5 149 E2IV87 BH3 interacting domain death agonist (Fragment) OS=Saimiri boliviensis GN=Bid PE=2 SV=1
11 : F6WQU1_MACMU 0.76 0.85 2 197 19 210 197 2 6 210 F6WQU1 Uncharacterized protein (Fragment) OS=Macaca mulatta GN=BID PE=4 SV=1
12 : F7H9R6_MACMU 0.76 0.88 3 197 1 195 195 0 0 195 F7H9R6 Uncharacterized protein (Fragment) OS=Macaca mulatta GN=BID PE=4 SV=1
13 : F7A8I6_HORSE 0.69 0.86 7 197 1 190 191 1 1 190 F7A8I6 Uncharacterized protein (Fragment) OS=Equus caballus GN=BID PE=4 SV=1
14 : F1Q0Y3_CANFA 0.67 0.84 2 194 9 203 195 2 2 203 F1Q0Y3 Uncharacterized protein (Fragment) OS=Canis familiaris GN=BID PE=4 SV=2
15 : F7ACD0_HORSE 0.67 0.84 7 197 1 190 191 1 1 190 F7ACD0 Uncharacterized protein (Fragment) OS=Equus caballus GN=BID PE=4 SV=1
16 : D2HVP9_AILME 0.65 0.84 7 194 1 188 189 2 2 188 D2HVP9 Putative uncharacterized protein (Fragment) OS=Ailuropoda melanoleuca GN=PANDA_016465 PE=4 SV=1
17 : G1PYL8_MYOLU 0.65 0.84 8 197 1 191 191 1 1 191 G1PYL8 Uncharacterized protein (Fragment) OS=Myotis lucifugus GN=BID PE=4 SV=1
18 : L5MJN0_MYODS 0.65 0.84 2 194 54 247 194 1 1 259 L5MJN0 BH3-interacting domain death agonist OS=Myotis davidii GN=MDA_GLEAN10003632 PE=4 SV=1
19 : M1EET9_MUSPF 0.65 0.82 2 196 2 196 196 2 2 196 M1EET9 BH3 interacting domain death agonist (Fragment) OS=Mustela putorius furo PE=2 SV=1
20 : M3WEH6_FELCA 0.65 0.83 7 197 1 192 193 3 3 192 M3WEH6 Uncharacterized protein (Fragment) OS=Felis catus GN=BID PE=4 SV=1
21 : BID_PIG 0.64 0.83 3 197 1 192 195 1 3 192 Q4JHS0 BH3-interacting domain death agonist OS=Sus scrofa GN=BID PE=2 SV=1
22 : G1MGI0_AILME 0.64 0.84 4 194 2 192 192 2 2 195 G1MGI0 Uncharacterized protein (Fragment) OS=Ailuropoda melanoleuca GN=BID PE=4 SV=1
23 : BID_MOUSE 1DDB 0.63 0.81 3 197 1 195 197 3 4 195 P70444 BH3-interacting domain death agonist OS=Mus musculus GN=Bid PE=1 SV=2
24 : L5JTG3_PTEAL 0.63 0.85 2 194 74 267 194 1 1 279 L5JTG3 BH3-interacting domain death agonist OS=Pteropus alecto GN=PAL_GLEAN10022544 PE=4 SV=1
25 : G3HQ86_CRIGR 0.62 0.79 3 197 1 194 196 3 3 194 G3HQ86 BH3-interacting domain death agonist OS=Cricetulus griseus GN=I79_012981 PE=4 SV=1
26 : S9XDC5_9CETA 0.62 0.84 7 194 170 354 189 2 5 362 S9XDC5 BH3 interacting domain death agonist transcript-like protein OS=Camelus ferus GN=CB1_000357007 PE=4 SV=1
27 : A8ASI9_RAT 0.61 0.79 3 197 1 196 197 3 3 196 A8ASI9 BH3 interacting domain death agonist OS=Rattus norvegicus GN=Bid PE=2 SV=1
28 : BID_RAT 0.61 0.79 3 197 1 196 197 3 3 196 Q9JLT6 BH3-interacting domain death agonist OS=Rattus norvegicus GN=Bid PE=2 SV=2
29 : H0WLJ8_OTOGA 0.61 0.78 5 194 1 198 198 3 8 201 H0WLJ8 Uncharacterized protein (Fragment) OS=Otolemur garnettii GN=BID PE=4 SV=1
30 : I3N331_SPETR 0.61 0.78 4 197 2 195 195 2 2 195 I3N331 Uncharacterized protein (Fragment) OS=Spermophilus tridecemlineatus GN=BID PE=4 SV=1
31 : L8IKY9_9CETA 0.59 0.78 6 194 1 187 191 3 6 193 L8IKY9 BH3-interacting domain death agonist (Fragment) OS=Bos mutus GN=M91_14167 PE=4 SV=1
32 : Q05KI6_BOVIN 0.58 0.77 3 194 1 190 194 3 6 192 Q05KI6 BH3 interacting domain death agonist transcript variant 1 OS=Bos taurus GN=BID1 PE=2 SV=1
33 : Q17QH5_BOVIN 0.58 0.77 3 197 1 193 197 3 6 193 Q17QH5 BH3 interacting domain death agonist OS=Bos taurus GN=BID PE=2 SV=1
34 : G3T1D2_LOXAF 0.57 0.80 7 194 1 192 192 2 4 195 G3T1D2 Uncharacterized protein (Fragment) OS=Loxodonta africana GN=BID PE=4 SV=1
35 : K9IQW9_DESRO 0.57 0.78 1 197 10 207 199 3 3 207 K9IQW9 Putative bh3 (Fragment) OS=Desmodus rotundus PE=2 SV=1
36 : G5BWN8_HETGA 0.55 0.81 3 197 1 196 197 3 3 310 G5BWN8 BH3-interacting domain death agonist OS=Heterocephalus glaber GN=GW7_16358 PE=4 SV=1
37 : G1TB99_RABIT 0.53 0.75 2 192 9 205 198 3 8 210 G1TB99 Uncharacterized protein OS=Oryctolagus cuniculus GN=BID PE=4 SV=1
38 : H0W5F0_CAVPO 0.52 0.77 4 194 1 190 192 2 3 193 H0W5F0 Uncharacterized protein (Fragment) OS=Cavia porcellus GN=Bid PE=4 SV=1
39 : W5PVK6_SHEEP 0.52 0.76 2 194 1 189 194 3 6 192 W5PVK6 Uncharacterized protein (Fragment) OS=Ovis aries GN=BID PE=4 SV=1
40 : Q05KI5_BOVIN 0.46 0.60 3 194 1 143 193 5 51 145 Q05KI5 BH3 interacting domain death agonist transcript variant 2 OS=Bos taurus GN=BID2 PE=2 SV=1
41 : G3W5W1_SARHA 0.45 0.70 15 197 4 188 187 4 6 188 G3W5W1 Uncharacterized protein OS=Sarcophilus harrisii GN=BID PE=4 SV=1
42 : G3W5W2_SARHA 0.45 0.69 21 194 19 194 178 4 6 194 G3W5W2 Uncharacterized protein (Fragment) OS=Sarcophilus harrisii GN=BID PE=4 SV=1
43 : M7ARC5_CHEMY 0.45 0.70 22 191 42 214 175 5 7 215 M7ARC5 BH3-interacting domain death agonist OS=Chelonia mydas GN=UY3_17571 PE=4 SV=1
44 : F7CU55_MONDO 0.43 0.71 22 197 81 261 184 5 11 261 F7CU55 Uncharacterized protein OS=Monodelphis domestica GN=BID PE=4 SV=2
45 : BID_CHICK 0.42 0.70 21 194 16 193 178 3 4 193 Q8JGM8 BH3-interacting domain death agonist OS=Gallus gallus GN=BID PE=2 SV=2
46 : G1NL76_MELGA 0.42 0.69 21 194 16 193 180 5 8 193 G1NL76 Uncharacterized protein (Fragment) OS=Meleagris gallopavo GN=BID PE=4 SV=2
47 : K7G3T4_PELSI 0.42 0.72 18 191 7 184 179 5 6 184 K7G3T4 Uncharacterized protein (Fragment) OS=Pelodiscus sinensis GN=BID PE=4 SV=1
48 : R0M701_ANAPL 0.41 0.68 22 192 14 188 176 4 6 188 R0M701 BH3-interacting domain death agonist (Fragment) OS=Anas platyrhynchos GN=Anapl_12055 PE=4 SV=1
49 : U3IN21_ANAPL 0.41 0.68 22 194 17 193 178 4 6 193 U3IN21 Uncharacterized protein OS=Anas platyrhynchos GN=BID PE=4 SV=1
50 : G1KMF0_ANOCA 0.39 0.68 22 194 17 186 175 5 7 186 G1KMF0 Uncharacterized protein (Fragment) OS=Anolis carolinensis GN=BID PE=4 SV=1
51 : G3UR49_MELGA 0.39 0.66 3 194 1 196 198 5 8 196 G3UR49 Uncharacterized protein (Fragment) OS=Meleagris gallopavo GN=BID PE=4 SV=1
52 : U3K4T9_FICAL 0.38 0.68 23 192 15 182 173 4 8 184 U3K4T9 Uncharacterized protein OS=Ficedula albicollis GN=BID PE=4 SV=1
53 : H0W6L8_CAVPO 0.37 0.63 3 196 1 188 195 3 8 189 H0W6L8 Uncharacterized protein (Fragment) OS=Cavia porcellus GN=LOC100730546 PE=4 SV=1
54 : V8P747_OPHHA 0.35 0.60 18 187 93 249 172 5 17 264 V8P747 BH3-interacting domain death agonist (Fragment) OS=Ophiophagus hannah GN=BID PE=4 SV=1
## ALIGNMENTS 1 - 54
SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
1 1 A G 0 0 125 2 53 A
2 2 A S - 0 0 126 15 7 AAA AAA A A AA A A A A
3 3 A M S S+ 0 0 152 30 13 MMMMMMMMM ML M MM M MMM MM MM MMV LM L V
4 4 A D + 0 0 148 33 33 DDDDDDDDD DS E DD DDDDD DD N DD NDDDSD S T
5 5 A C S S- 0 0 96 34 68 CCCCCCCCC CP S PS SASPS SSCS LL PAPGSL S C
6 6 A E S S+ 0 0 175 35 61 EEEEEEEEE EQ K KK KQEKQ EEDQQKK QKKKQK S V
7 7 A V + 0 0 84 41 22 VVVVVVVVV VVVVVV GVVVVVIVVVVVVVVVVIVVVVV H A
8 8 A N + 0 0 130 42 31 NNNNNNSSS SSSSSSSSSSSSSSSSSSSSSSSSHGSGSS S S
9 9 A N + 0 0 140 42 18 NNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNSNNN R T
10 10 A G S S- 0 0 79 42 9 GGGGGGGGG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGG G M
11 11 A S - 0 0 108 42 46 SSSSSSSSS SSSSSPSSSSSPSASASSSSPPPSSAPAPP K D
12 12 A S - 0 0 93 42 35 SSSGSGGGD GGGGGGCGGSSGGRGGGGGDSGGGGGGGGG S A
13 13 A L + 0 0 120 42 52 LLLLLLLLL LLLPLLLLLLLLLLLPLLLLPPPLLFPTLP D V
14 14 A R + 0 0 105 42 67 RRRRRSRRQ RRQQQQQQQQQQGQDQGGRRGGGQGRRRGG G R
15 15 A D > + 0 0 80 43 40 DDDDDDDDD DDDDDDDDDDDDAHTDAADNDDDNVDDGDDD S K
16 16 A E T >> + 0 0 40 43 6 EEEEEEEEE EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEN D E
17 17 A C H 3> S+ 0 0 76 43 76 CCCCCCCCR CCHRHHRRRRRHHHHRHHHYRRRRRSHLRRR H Q
18 18 A I H <> S+ 0 0 28 45 38 IIIIIIVVI VVIIIIIIIIIIIIIIIILITTTILIIVTTQ V M IV
19 19 A T H <> S+ 0 0 5 45 15 TTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT E E TA
20 20 A N H X S+ 0 0 18 45 52 NNNNNNNNN NNHNHNDDNNNNDDNSNNGNSSSNDNNDSSS R R NG
21 21 A L H X S+ 0 0 24 48 7 LLLLLLLLL LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL MMI M LI
22 22 A L H X S+ 0 0 0 53 2 LLLLLLLLL LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL LV
23 23 A V H X S+ 0 0 1 54 24 VVVVVVVVV VVVVVVVVVVVVVVVVVVVVLLLVVVVVLLLLVLLLVLLLLLLL
24 24 A F H X S+ 0 0 53 54 9 FFFFFFFFF FFFFFFFFFFFFFFFFFFYLLLLFFYLFLLYYYFFFYFFYFFFY
25 25 A G H X S+ 0 0 11 54 40 GGGGGGGGG GGSGSGGGGGGGGGGSGGGDGGGSGSGGGGNNSNAASAASATGS
26 26 A F H X S+ 0 0 4 53 0 FFFFFFFFF FFFFFFFFFFFFFF.FFFFFFFFFFFFFFFFFFFFFFFFFFFFF
27 27 A L H < S+ 0 0 3 54 0 LLLLLLLLL LLLLLLLLLLLLLLFLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
28 28 A Q H >< S+ 0 0 69 55 37 QQQQQQQQQQQQQQQQQQQQQQQQLQRRQQQQQKQHQCQQQQQQAAQEEQADQE
29 29 A S H 3< S+ 0 0 1 55 58 SSSSSSSSSSSSNNNNNNSNSNSNQSNNSSSSSNHTSSSSSSNCEENEEHEASN
30 30 A C T 3< S+ 0 0 4 55 46 CCCCCCCCCCCCCCCCCCYCCCSCNCNNCFCCCCSRCRCCSSCSSSCSSSSSSS
31 31 A S S < S- 0 0 47 55 48 SSSSSSSSSSSSSSSSSSSSPSGCSSDDSSPPPPPNCDPPGGHSSSHSSRSSSS
32 32 A D - 0 0 88 52 55 DDDDDDDDNNDDKNKNNNDNHN.NKP..NDHHHSSNSNNHNNNNGGNGGDGDDD
33 33 A N S S+ 0 0 97 54 77 NNSNNNNNHHNNRYRSYYSYAS.SYSRRSCSSSCDSCSSSNNCSCCCCCCCCPI
34 34 A S S S+ 0 0 112 55 83 SSSSSSSSSSSSHNHNNNNNSNCNHSDDGKCCCHKNSNCCLLDFEEAEETEQNT
35 35 A F S > S+ 0 0 68 55 7 FFFFFFFFFFFFFFFFFFFFFFTFFFFFFFFFFFLFFFFFFFFIFFFFFFFFFF
36 36 A R H >> + 0 0 142 55 62 RRRRRRRRHQRRYHYHHHHHHHRHHRHHQHQQQHQHHHQQQQRQQRRKKVRKSA
37 37 A R H 3> S+ 0 0 162 55 70 RRRRRRRRRARRKEKKKKKKKKQKRRQQRQRRREEPESRRTTETEEEEESEDQS
38 38 A E H >> S+ 0 0 76 55 19 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEQQEQQDQQET
39 39 A L H < S+ 0 0 4 55 0 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
43 43 A G G >< S+ 0 0 33 55 48 GGGGGGGGGGGGGGGGGGGGGGGGGGGGgGGGGSGGgGGGddrgqqkrrKqhGK
44 44 A H G 3 S+ 0 0 156 55 75 HHHHHHRRHRRRHRHHHHRRHHRHQHQQtQHHHYRQaQHHaavpggviiNgqRQ
45 45 A E G < S+ 0 0 148 55 57 EEEEEEEEEEEEEEEEDDEEEEEDEQEEHEEEEETEEEEEVVMHVLIVVELIEQ
46 46 A L < + 0 0 25 55 17 LLLLLLLLLLLLLLLVLLLLLVLLLLLLLLLLLLLLLLFLFFVFLLVYYLLMLL
47 47 A P - 0 0 88 55 54 PPPPPPPPPPPPPPPSSSPPPSPPPSPPLPPPPPPPAPSPGGSQCCPPPLCSRL
48 48 A V - 0 0 32 54 65 VVVVVVVV.HVVVVVMVVVVVMVVVMVVVVGGGLVVDGGGSSPGSARLLVACVA
49 49 A L + 0 0 141 54 80 LLLLLLPP.WPPQPQPPPPpHPQPPCQQrRHHHPPGsRHHrrpGvvpQQSvQQP
50 50 A A - 0 0 24 40 57 AAAAAAAA..AAAAAAAAAa.AAA..VVhT...ATVd...ggn.dgsDD.g.G.
51 51 A P S S- 0 0 99 44 91 PPPPPPAA..AAYYYYCCHY.YYYV.YYLY...HGCC...CCFGAVFIIRV.SK
52 52 A Q - 0 0 107 46 80 QQQQQQQQQ.QQLLLLLLLL.LWPY.LLHL...LPLCP..SSLLLQLLLIQ.KQ
53 53 A W S S- 0 0 216 47 95 WWWWWWWWW.WWWKWQWWQQTQERL.EEEE...RQESE..EESECSHYYSS.QP
54 54 A E S S+ 0 0 112 55 79 EEEEEEEEEEEEEEEEEEEESEAEDTGGEGLLLEGAYVLLQQDDYYDCCDYAGS
55 55 A G + 0 0 69 55 70 GGGGGGAAEEAADDDDNNEDGDDDAADDLEFFFEPDDDFFDDENDDEDDDDSAV
56 56 A Y S S- 0 0 199 55 84 YYYYYYYYppYYHyHyhhqhSylydlrrdrhhhYchDhyhYYfYssfssdsdsy
57 57 A D - 0 0 123 52 17 DDDDDDDDeeDDDdDdddddDddddddddddddDedDddd..d.ggdggdgded
58 58 A E S S+ 0 0 173 55 17 EEEEEEEEEEEEEEEGEEGGEGEEEEEEEEEEEEEEEEEEEEgEEEgEEdEEEg
59 59 A L S S- 0 0 144 55 0 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLlLLLlLLlLLLl
60 60 A Q - 0 0 171 55 2 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEQ
61 61 A T - 0 0 115 55 4 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTIT
62 62 A D - 0 0 136 55 0 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
63 63 A G - 0 0 58 55 0 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
64 64 A N S S- 0 0 133 54 25 NNNNNNNNNNNNNN.NSNNNNNSNSSSSSNNNNNSNNNNNNNNNNNNNNNNNPN
65 65 A R + 0 0 208 55 23 RRRRRRRRRRRRRRNRQQRRRRQRRQRRRRRRRRRRHRRRRRRRRRRRRRRRAN
66 66 A S S S- 0 0 113 55 63 SSSSSSSSSGSSCCRCYYCCCCACAWAAAACCCNCGALSCCCSSSSSSSCSSQF
67 67 A S - 0 0 110 55 38 SSSSSSSSSSSSSSCSSSGSSSSSSSSSSSSSSSSSSSSSYYGCGGGGGGGGSG
68 68 A H - 0 0 108 55 54 HHHHHHHHHHHHHYSYHHHRYYRHRHRRRLHHHHHRFHYHFFRHHHRHHRHHCR
69 69 A S + 0 0 114 54 75 SSSSSSSSSASSFFHFFF.FFFSISPSSFFFFFFFLLFFFDDFFLLFFFFLFMV
70 70 A R > - 0 0 154 54 92 RRRRRRRRHHRR.LFLVVFLMLFVYLFFYMPPPHVLQHSPMMSEQQQQQQQQEE
71 71 A L T 3 S- 0 0 131 55 90 LLLLLLMMVMMMVDVELLLDEEnLHGyyAGlllfsYMGVLSSNENNNNNANNSD
72 72 A G T 3 S+ 0 0 60 48 38 GGGGGEGGGGGGAGA.EEASD.gEGGggERaaasggGGA...GEGgGGG.gGS.
73 73 A R < + 0 0 187 48 63 RRRRRRRRRRRRRGRSSSSEASRRRARRRIEEErRrRR..RR..EvD..RvE.R
74 74 A I S > S+ 0 0 88 52 82 IIIIIIIIIIIIAAAGRREEAGIEIAIIIEAAALNRARA.EE.ELLLEEELL.V
75 75 A E T 3 S+ 0 0 72 54 31 EEEEEEEEEEEEEREEEEETEEEEQDEEEAEEEEREEEE.EEEEVDEQQEDEEL
76 76 A A T 3 S+ 0 0 83 55 78 AAAAAAAAAAAAAgARTTRDTRPTPTPPADTTTQGGAATAFFPSPPLvvVPLKG
77 77 A D < - 0 0 78 43 23 DDDDDDDDDDGGDdDDDDD.DDDEDVDDD.DDDD..GDD.SSDDD..dd.....
78 78 A S + 0 0 71 48 30 SSSSSSSSSS.SSSSSSSSSSSSSSSSSSSSSSSSDSSS.DDSSP.GPP..P..
79 79 A E + 0 0 138 50 36 EEEEEEEEEE.EEEEQEEQEEQEEEAEEGEEEEGESEEE.SSVEEESEE.EP..
80 80 A S S >> S- 0 0 63 51 65 SSSSSSSSSS.TSSSGSSGSSGSNSSSSSSRRRSTESSR.EEVSVVSVVPVT..
81 81 A Q H 3> S+ 0 0 147 51 36 QQQQQQQQQQ.QQQQQQQQQQQQQQQQQQQQQQQQNQQQ.NNDQNNVNNDNN..
82 82 A E H 3> S+ 0 0 105 52 14 EEEEEEEEEE.SEEEEDDEEEEEEEEDDEEEEEEEQEEE.QQEEEEEEEEEEE.
83 83 A D H <> S+ 0 0 36 53 26 DDDDDDDDDDRKEEEEEEEEAEEEDEEEDEEEEEDEEEE.EEDEAEDEEEEEE.
84 84 A I H X S+ 0 0 58 53 39 IIIIIIVVVIWKIIIIIIIIVIIIVAVVVVAAAVVIVLA.IIIIIIIIIIIVT.
85 85 A I H X S+ 0 0 34 53 26 IIIIIIIIIIPKIIIIIIIIIIIIIIIIIIVVVIIIIIV.IIFIVVFVVFVIL.
86 86 A R H X S+ 0 0 121 53 50 RRRRRRRRRRAKQQQQQQQQRQHQQWHHQQRRRQRHRQR.QQRQRRQRRRRRL.
87 87 A N H X S+ 0 0 43 53 76 NNNNNNNNSNPKHDHDNNDDDDNNRDNNNNEEESNSNHE.RRLRTTVTTITIH.
88 88 A I H X S+ 0 0 45 53 17 IIIIIIIIIIPKIIIIIIIIIIIIIIIIFIVVVIIIIIV.IIIIIIIIIIIIM.
89 89 A A H X S+ 0 0 0 53 15 AAAAAAAAAAPKAAAAAAAAAAAAAAAAAAAAAAAAAAA.AAGAAAGAAGAAG.
90 90 A R H X S+ 0 0 81 54 69 RRRRRRRRRRSRRRRRRRRRRRRRHRRRRRRRREQWRSR.TTAMAAAAAAAAMA
91 91 A H H >X S+ 0 0 123 54 41 HHHHHHHHHQPNQQQQQQQQHQHQHQHHRHQQQRQHRQQ.HHQQQQQQQQQQTR
92 92 A L H 3X S+ 0 0 51 54 9 LLLLLLLLLLKRLLLLLLLLLLLLLLLLLLLLLLLLLLL.LLLLLLLLLLLLLL
93 93 A A H 3X S+ 0 0 12 54 5 AAAAAAAAAAPVAAAAAAAAAAAAAAAAAAAAAAAAAAA.AAAAAAAAAAAAAA
94 94 A Q H X S+ 0 0 38 54 12 DDDDDDDDDDVCDDDDDDDDDDDDDDDDDDDDDDDDDDD.DDDDDDDDDDDDGD
98 98 A S H 3< S+ 0 0 69 54 76 SSSSSSSSSSAPRRRDRRDRRDERETEESERRREMERER.NNQNQQQQQKQQHK
99 99 A M H 3< S+ 0 0 134 54 27 MMMMMMMMMMSGMMMMMMMMMMMMLMLLMMLLLMMLMML.IIVILLVLLLLFML
100 100 A D H X< S+ 0 0 23 54 38 DDDDDDDDDDYWDDDDDDDDEDDDNGDDDDEEEEDDDEE.EEAEDDADDTDDEA
101 101 A R T 3< S+ 0 0 221 54 74 RRRRRRRRRRWRDHDHRRRHYHHSHRHHRRGGGSHRHHG.SSRNKKHKKAKKSA
102 102 A S T 3 S- 0 0 92 54 58 SSSSSSSSSSAASSSSSSSSGSNRSSSSSSSSSQRSHKS.SSESQQEEEEQEKE
103 103 A I < - 0 0 57 54 11 IIIIIIIIIIQVIIIIIIIIIIIIIIIIIIIIIVVIIII.IIIIIIIVVIIILI
104 104 A P > - 0 0 61 54 68 PPPPPPPPPPPVHHHHPPHHRHQPQHQQPQRHHHSQQQH.QQQQKKHKKEKQDE
105 105 A P T 3 S- 0 0 128 54 34 PPPPPPPPLPPYPPPPPPPPPPPPPPPPPPPPPPPPPAP.PPPPAAPAATAAPH
106 106 A G T 3 S+ 0 0 67 54 74 GGGGGGGGDGRVRGRGRRGRGGTRTGTTREGGGSSGESG.SSRRKKAKKSKRSP
107 107 A L X> + 0 0 65 54 27 LLLLLLLLLLLQLLLLLLLVLLLVLLLLLLMMMLLLLVM.LLVVVVVVVVVVLF
108 108 A V H 3> S+ 0 0 1 54 15 VVVVVVVVVVQYVVVMVVVVVMVVVIVVVVVVVVVVLVV.VVVVVVVVVIVVVV
109 109 A N H 3> S+ 0 0 69 54 56 NNNNNNNNDNFTNNNNNNNNDNRNRHRRNNAAAQDNNHA.DDNDNNNNNQNRGH
110 110 A G H X> S+ 0 0 25 54 67 GGGGGGGGRRQWNNNNHHNNSNQYQGQQNEGGGNHQNQS.NNDEDDDDDNDDRN
111 111 A L H 3X S+ 0 0 21 54 4 LLLLLLLLLLRLLLLLLLLLLLLLLLLLLLLLLLLLLLL.LLLLLLLLLLLLLL
112 112 A A H 3X S+ 0 0 3 54 51 AAAAAAAAAAPPAAAAAAAAAAAAAAAAVVAAAAVAVSV.IIVVVVLVVAVVAA
113 113 A L H X S- 0 0 41 54 44 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNVVVDDNVDV.IINNNNNNNRNNDV
118 118 A T G >4 S- 0 0 98 54 84 TTTTTTTTAATTVVVVGGRVQVGVVGGGPARRRRRPNSR.IIEVEEEEEEEEPE
119 119 A S G 34 S+ 0 0 99 54 53 SSSSSSSSCGSSNNNNNNRNSNSDSSSSSGSSSNNGDSS.NNNNNNNNNNNRSN
120 120 A R G X>> + 0 0 163 54 52 RRRRRRRRRRRRLLLLLLLLLLLLLLLLLLLLLLLLHLL.LLLLLLMLLMLLLV
121 121 A S I S+ 0 0 0 55 14 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSASSSSPPSSSSPSSS
122 122 A E I 3>5S+ 0 0 102 55 51 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEPEEAAKTRRRRRKRRDS
123 123 A E I <>5S+ 0 0 147 55 7 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEETEEEQEEEEEEEEEQ
124 124 A D I <5S+ 0 0 49 55 29 DDDDDDDDDDDDDDDDDEDDDDDDDDDDNDDDDDGGDGDDDDEEEEEEEVEEDV
125 125 A R I >X S+ 0 0 28 55 79 DDDDDDDDDDDDCHCSCCCHGSCCCGCCHCCCCHCYRCCCYYRYCCRCCQCHCH
129 129 A L H X S+ 0 0 4 55 3 LLLLLLLLLLLLLLLLLLLLLLLLLFLLLLLLLLLLLLLLLLLLLLLLLILLML
130 130 A A H X S+ 0 0 7 55 47 AAAAAAAAAAAATATTAAAAATASAAAAADAAAAAAAAMADDSASSSSSSSSAS
131 131 A T H X S+ 0 0 80 55 71 TTTTTTTTSSTTSASAAAAAAAKAKTKKATAAATTASADAAANAQQDQQHQRAE
132 132 A A H X S+ 0 0 25 55 27 AAAAAAAAAAAAAAAAAAAAVAAAATAAATAAAAATATAAAATTAATAAVAATA
133 133 A L H X S+ 0 0 2 55 23 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLVVVVLLLMMVMVVVVVVVVLV
134 134 A E H X S+ 0 0 107 55 30 EEEEEEEEEEEEEEEEEEEEQEDEDGDDEKEEEDDEEGEEQQEEEEEEEQENQR
135 135 A Q H < S+ 0 0 121 55 51 QQQQQQQQQQQQQQQQQQRQQQEEEQEEQAQQQRQEQEQQQQGKGGEVVEGKEN
136 136 A L H >X S+ 0 0 79 55 36 LLLLLLLLLLLLVAVVVVVVLVVVVLVVVALLLVVVAVLLMMLVLLLLLLLLAV
137 137 A L H >< S+ 0 0 12 55 45 LLLLLLLLLLLLMMMMMMMLVMKMKLKKMMMMMMLMMMMMMMVMAAMAAVALLV
138 138 A Q T 3< S+ 0 0 163 55 54 QQQQQQQQQQQQQQQQHHQQHQTKTQTTQQQQQQQQEQRQQQRdRRRRRRRTRA
139 139 A A T <4 S+ 0 0 77 55 52 AAAAAAAAAVAATTTTTTTTSTATAASSTTTTTTATTTTTTTTtAATAAKASAR
140 140 A Y S << S- 0 0 112 55 61 YYYYYYYYHHYYYYYYYYYYYYFYFCFFCYCCCCCYWCCCIIIIIVVIIMVIFM
141 141 A P + 0 0 133 55 9 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPLPAPPPPPPPSPPPPPPPPPP
142 142 A R + 0 0 166 55 87 RRRRRRTTTMTTKKKMKKTKAMRKRARRAKPPPLRTAAAPLLLLSSLSSLSSEP
143 143 A D S S+ 0 0 159 55 4 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDEDDDDDDE
144 144 A M S S- 0 0 141 55 21 MMMMMMMMMMMMMMMMMMMMMMMMMVMMLMMVVMMMMVVVLLMILLMLLMLMAM
145 145 A E - 0 0 113 55 22 EEEEEEEEDDEEEEEEEEEEGEEEEDEETEDDDEEEEEDDEEEGEEEEEEEAHE
146 146 A K S >>S+ 0 0 53 55 63 KKKKKKKKKKKKKKKEKKDRQENRNQNNENHHHLEQRQHHQQQQQQRRRKQQSQ
147 147 A E H >5S+ 0 0 60 55 5 EEEEEEEEEEEEEEEEEEEEEEDEEEDDEEEEEEEEEEEEEEEEEEEEEEEEDE
148 148 A K H >5S+ 0 0 121 55 3 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKQK
149 149 A T H >5S+ 0 0 76 55 42 TTTTTTTTTTTTTTTTTTTTTTATATAAATTTTKTAAATTAAAAAAAAAAAATA
150 150 A M H X5S+ 0 0 16 55 43 MMMMMMMMMMMMMMMMMMMVLMMMMLMMTMQQQKMKTVQQQQMTMMMMMMMMMM
151 151 A L H XXS+ 0 0 0 55 0 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
152 152 A V H X5S+ 0 0 34 55 34 VVVVVVVVVVVVMMMIMMIMVIIMIVIILILLLMLIMILLLLVLVVVVVVVVTV
153 153 A L H X5S+ 0 0 59 55 15 LLLLLLLLLLLLLLLLLLLLLLMLMLMMLMLLLLVTLMLLLLLLLLLLLILLLA
154 154 A A H X5S+ 0 0 2 55 44 AAAAAAAAAAAASASATTAATATTTTTTITTTTTTATTTTAAATAAAAASAATA
155 155 A L H X5S+ 0 0 1 55 5 LLLLLLLLLLLLMMMMMMMMMMMMLMMMMMMMMMMMMMMMMMMMMMMMMMMMMM
156 156 A L H XX S+ 0 0 26 55 15 KKKKKKKKKEKKKKKKKKKKKKKKSEKKKKKKKKKKKKKKKKTKKKTKKKKKKK
161 161 A V H 3X S+ 0 0 0 55 7 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVIIIVVVLVIIVVVVVVVVVVVIVV
162 162 A A H 3< S+ 0 0 2 55 23 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAMMAMAATAAVAVAA
163 163 A S H << S+ 0 0 39 55 60 SSSSSSSSDNSSNDNDDDDDEDSDSSSSDNDDDDSDEDDDTTNTNNNNNNNNRN
164 164 A H H < S+ 0 0 84 55 39 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHKHQQKKKSQTQV
165 165 A T >< + 0 0 44 55 67 TTTTTTTTTTTTTTTTTTTTSTATETAATTSSSMTTTTSSAAMAMVMVVVVMRV
166 166 A P T 3 S+ 0 0 32 55 5 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPMP
167 167 A S T 3 S+ 0 0 106 55 37 SSSSSSSSSSSSSSSSSSSSASSSSASSSSAAASSSSRAASSSPSSSFFSSSGA
168 168 A L <> + 0 0 16 55 0 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
169 169 A L H >> S+ 0 0 11 55 3 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLFLLFFLFLLLLLLLLLL
170 170 A R H 3> S+ 0 0 117 55 37 RRRRRRRRRRRRRRRRHHRRRRRRRQRRPHRRRRRRRRRRRRHRQQQQQQQRPQ
171 171 A D H 3> S+ 0 0 23 55 61 DDDDDDDDDDDDDDDDDDEDDDDGDDDDVDDDDDTDAVDDSSRSRRRRRQRRRQ
172 172 A V H X S+ 0 0 1 55 0 FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFYFFFFFFFFFFFFFYFF
174 174 A H H 3X S+ 0 0 56 55 69 HHHHHHQQRRQQRHRRRRRRHRHHRRRRRRHHHRHHRDRHYYNQSSNSSNSDNN
175 175 A T H 3X S+ 0 0 3 55 26 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTATTTTTTATTTIITLTTTTTATAIT
176 176 A T H << S+ 0 0 0 55 10 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAVTTTTTTTTTTTTTTVT
177 177 A V H X S+ 0 0 10 55 4 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVGV
178 178 A N H X S+ 0 0 55 55 29 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTNNNTDTTDDNDNNNNNNNNRN
179 179 A F H <>S+ 0 0 18 55 10 FFFFFFFFFFFFFFFFVVFFFFFFFFFFFFFFFFFFLFFFYYYYYYYYYYYYFY
180 180 A I I >>>S+ 0 0 0 54 8 IIIIIIIII IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIMMVIIIIIIIIMII
181 181 A N I 3<5S+ 0 0 37 54 28 NNNNNNNNN NNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSSSNSNVN
182 182 A Q I 3<5S- 0 0 109 54 6 QQQQQQQQQ QQQQQQQQQQQQQQQQQQRQQQQQQQQQQQQQQQQQQQQQQQRQ
183 183 A N I <45S+ 0 0 123 54 19 NNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNDNNNNNNNHHNHHNHQNN
184 184 A L I >X< + 0 0 22 54 3 LLLLLLLLL LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLFLLFFLLFLL
185 185 A R H >>< + 0 0 131 54 79 RRRRRRRRR RRLLLFLLFLLFFLFLFFLFLLLLPLLLLLIIHRHHHHHHHHFH
186 186 A T H 34 S+ 0 0 90 54 58 TTTTTTAAA AATTTTTTTTTTSTTTSSATAAATTTATAATTNTNNNGGDNDSD
187 187 A Y H X> S+ 0 0 5 54 15 YYYYYYYYY YYYYYYYYYYYYYYSYYYSYYYYYYYYYSYYYYYYYYYYYYYCY
188 188 A V H >S+ 0 0 36 53 56 SSSSSSSSS SSNNNNNNNNNNNNNNDDNDNNNNDDNDNNNNNNRRNRRNRED
191 191 A L H <5S+ 0 0 1 53 4 LLLLLLLLL LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLMMMMMLMML
192 192 A A H <5S+ 0 0 3 51 54 AAAAAAAAT AAVVVVVVVVVVVLLVVVAVVVVAVIAVVVVV TLL VLALLV
193 193 A R H <5S+ 0 0 187 48 16 RRRRRRRRR RRRRRRRRRRQRRRRQRRRRRRRRRR RRRRR RRR RPR D
194 194 A N T <5S- 0 0 68 48 27 NNNNNNNNN NNNNNNNNNNSNNNNNNNNNNNNNNN NSNNN NEE EEE S
195 195 A G S