Complet list of 2axk hssp file
Complete list of 2axk.hssp file
HSSP HOMOLOGY DERIVED SECONDARY STRUCTURE OF PROTEINS , VERSION 2.0 2011
PDBID 2AXK
THRESHOLD according to: t(L)=(290.15 * L ** -0.562) + 5
REFERENCE Sander C., Schneider R. : Database of homology-derived protein structures. Proteins, 9:56-68 (1991).
CONTACT Maintained at http://www.cmbi.ru.nl/ by Maarten L. Hekkelman
DATE file generated on 2014-05-16
HEADER TOXIN 05-SEP-05 2AXK
COMPND MOL_ID: 1; MOLECULE: DISCREPIN; CHAIN: A; ENGINEERED: YES
SOURCE MOL_ID: 1; SYNTHETIC: YES; OTHER_DETAILS: THIS SEQUENCE OCCURS NATURAL
AUTHOR A.PROCHNICKA-CHALUFOUR,G.CORZO,H.SATAKE,M.-F.MARTIN- EAUCLAIRE,A.R.MUR
DBREF 2AXK A 1 38 UNP P84777 KA156_TITDI 1 38
SEQLENGTH 38
NCHAIN 1 chain(s) in 2AXK data set
NALIGN 37
NOTATION : ID: EMBL/SWISSPROT identifier of the aligned (homologous) protein
NOTATION : STRID: if the 3-D structure of the aligned protein is known, then STRID is the Protein Data Bank identifier as taken
NOTATION : from the database reference or DR-line of the EMBL/SWISSPROT entry
NOTATION : %IDE: percentage of residue identity of the alignment
NOTATION : %SIM (%WSIM): (weighted) similarity of the alignment
NOTATION : IFIR/ILAS: first and last residue of the alignment in the test sequence
NOTATION : JFIR/JLAS: first and last residue of the alignment in the alignend protein
NOTATION : LALI: length of the alignment excluding insertions and deletions
NOTATION : NGAP: number of insertions and deletions in the alignment
NOTATION : LGAP: total length of all insertions and deletions
NOTATION : LSEQ2: length of the entire sequence of the aligned protein
NOTATION : ACCNUM: SwissProt accession number
NOTATION : PROTEIN: one-line description of aligned protein
NOTATION : SeqNo,PDBNo,AA,STRUCTURE,BP1,BP2,ACC: sequential and PDB residue numbers, amino acid (lower case = Cys), secondary
NOTATION : structure, bridge partners, solvent exposure as in DSSP (Kabsch and Sander, Biopolymers 22, 2577-2637(1983)
NOTATION : VAR: sequence variability on a scale of 0-100 as derived from the NALIGN alignments
NOTATION : pair of lower case characters (AvaK) in the alignend sequence bracket a point of insertion in this sequence
NOTATION : dots (....) in the alignend sequence indicate points of deletion in this sequence
NOTATION : SEQUENCE PROFILE: relative frequency of an amino acid type at each position. Asx and Glx are in their
NOTATION : acid/amide form in proportion to their database frequencies
NOTATION : NOCC: number of aligned sequences spanning this position (including the test sequence)
NOTATION : NDEL: number of sequences with a deletion in the test protein at this position
NOTATION : NINS: number of sequences with an insertion in the test protein at this position
NOTATION : ENTROPY: entropy measure of sequence variability at this position
NOTATION : RELENT: relative entropy, i.e. entropy normalized to the range 0-100
NOTATION : WEIGHT: conservation weight
## PROTEINS : identifier and alignment statistics
NR. ID STRID %IDE %WSIM IFIR ILAS JFIR JLAS LALI NGAP LGAP LSEQ2 ACCNUM PROTEIN
1 : KA156_TITDI 2AXK 1.00 1.00 2 38 25 61 37 0 0 61 P84777 Potassium channel toxin alpha-KTx 15.6 OS=Tityus discrepans PE=1 SV=2
2 : KAX2A_CENEL 0.53 0.72 4 38 3 38 36 1 1 38 P0C163 Potassium channel toxin alpha-KTx 2.10 OS=Centruroides elegans PE=1 SV=1
3 : KAX_BUTOS 0.53 0.72 7 38 29 60 32 0 0 60 B8XH38 Potassium channel toxin-like Tx677 OS=Buthus occitanus israelis PE=2 SV=1
4 : B8XH48_BUTOS 0.52 0.70 6 38 29 60 33 1 1 61 B8XH48 Putative potassium channel toxin Tx821 OS=Buthus occitanus israelis PE=3 SV=1
5 : B8XH43_BUTOS 0.51 0.66 4 38 26 60 35 0 0 60 B8XH43 Putative potassium channel toxin Tx753 OS=Buthus occitanus israelis PE=3 SV=1
6 : KAX28_CENEL 0.51 0.71 4 37 3 37 35 1 1 39 P0C161 Potassium channel toxin alpha-KTx 2.8 OS=Centruroides elegans PE=1 SV=1
7 : KAX29_CENEL 0.51 0.71 4 37 3 37 35 1 1 39 P0C162 Potassium channel toxin alpha-KTx 2.9 OS=Centruroides elegans PE=1 SV=1
8 : KAX34_LEIQH 0.51 0.70 2 38 2 37 37 1 1 38 P46110 Potassium channel toxin alpha-KTx 3.4 OS=Leiurus quinquestriatus hebraeus PE=1 SV=1
9 : E1F1U6_GIAIA 0.50 0.57 7 36 27 56 30 0 0 266 E1F1U6 Neurogenic locus notch-like protein OS=Giardia intestinalis (strain P15) GN=GLP15_3975 PE=4 SV=1
10 : KAX23_CENLL 0.50 0.74 2 38 1 38 38 1 1 38 P45629 Potassium channel toxin alpha-KTx 2.3 OS=Centruroides limpidus limpidus PE=1 SV=1
11 : KAX2D_CENSU 0.50 0.72 4 38 3 38 36 1 1 38 P85529 Potassium channel toxin alpha-KTx 2.13 OS=Centruroides suffusus suffusus PE=1 SV=1
12 : B8XH39_BUTOS 0.49 0.78 3 38 25 61 37 1 1 61 B8XH39 Putative potassium channel toxin Tx682 OS=Buthus occitanus israelis PE=3 SV=1
13 : B8XH44_BUTOS 0.49 0.57 2 38 25 61 37 0 0 73 B8XH44 Putative potassium channel toxin Tx771 OS=Buthus occitanus israelis PE=3 SV=1
14 : KA125_LYCMC 0.49 0.69 3 37 25 59 35 0 0 60 P0CH12 Potassium channel toxin alpha-KTx 12.5 OS=Lychas mucronatus PE=2 SV=1
15 : KAX21_CENNO 1SXM 0.49 0.71 4 37 3 37 35 1 1 39 P08815 Potassium channel toxin alpha-KTx 2.1 OS=Centruroides noxius PE=1 SV=3
16 : KAX31_ANDMA 1XSW 0.49 0.70 2 38 2 37 37 1 1 38 P24662 Potassium channel toxin alpha-KTx 3.1 OS=Androctonus mauretanicus mauretanicus PE=1 SV=2
17 : KAX36_MESMA 1BKT 0.49 0.68 2 38 23 58 37 1 1 60 Q9NII7 Potassium channel toxin alpha-KTx 3.6 OS=Mesobuthus martensii PE=1 SV=1
18 : KAX3C_ANDAM 0.49 0.68 2 38 2 37 37 1 1 38 P0C8R1 Potassium channel toxin alpha-KTx 3.12 OS=Androctonus amoreuxi PE=1 SV=1
19 : H2CYS1_PANCV 0.47 0.58 2 37 25 60 36 0 0 63 H2CYS1 Alpha-KTx-like peptide OS=Pandinus cavimanus PE=3 SV=1
20 : KA153_ANDMA 0.46 0.62 2 38 2 37 37 1 1 37 P60208 Potassium channel toxin alpha-KTx 15.3 OS=Androctonus mauretanicus mauretanicus PE=1 SV=1
21 : KA159_LYCMC 0.46 0.65 2 38 24 60 37 0 0 60 D9U2A8 Potassium channel toxin alpha-KTx 15.9 OS=Lychas mucronatus PE=2 SV=1
22 : KAX2B_CENEL 0.46 0.69 4 37 3 37 35 1 1 39 P0C164 Potassium channel toxin alpha-KTx 2.11 OS=Centruroides elegans PE=1 SV=1
23 : KAX38_HOTTS 0.46 0.68 2 38 2 37 37 1 1 38 P59886 Potassium channel toxin alpha-KTx 3.8 OS=Hottentotta tamulus sindicus PE=1 SV=1
24 : KAX3B_ODODO 0.46 0.70 2 38 2 37 37 1 1 38 P0C909 Potassium channel toxin alpha-KTx 3.11 OS=Odontobuthus doriae PE=1 SV=1
25 : KAX3D_MESEU 0.46 0.68 2 38 1 36 37 1 1 37 P86396 Potassium channel toxin alpha-KTx 3.13 OS=Mesobuthus eupeus PE=1 SV=1
26 : KAX44_TITOB 0.46 0.60 4 38 3 37 35 0 0 37 P60210 Potassium channel toxin alpha-KTx 4.4 OS=Tityus obscurus PE=1 SV=1
27 : KAX45_TITCO 0.46 0.66 4 38 25 59 35 0 0 59 Q5G8B6 Potassium channel toxin alpha-KTx 4.5 OS=Tityus costatus PE=1 SV=1
28 : KA158_MESMA 0.44 0.64 2 37 24 58 36 1 1 60 Q86BX0 Potassium channel toxin alpha-KTx 15.8 OS=Mesobuthus martensii PE=2 SV=1
29 : KAX22_CENMA 1MTX 0.44 0.72 4 38 3 38 36 1 1 39 P40755 Potassium channel toxin alpha-KTx 2.2 OS=Centruroides margaritatus PE=1 SV=1
30 : KAX6B_OPIMA 1WMT 0.44 0.64 2 37 22 57 36 0 0 63 P0C194 Potassium channel toxin alpha-KTx 6.11 OS=Opisthacanthus madagascariensis PE=1 SV=1
31 : KAX_ISOMC 0.44 0.61 2 37 24 59 36 0 0 60 P0CJ24 Potassium channel toxin ImKTx88 OS=Isometrus maculatus PE=2 SV=1
32 : B8XH28_BUTOS 0.43 0.57 2 38 24 59 37 1 1 59 B8XH28 Putative potassium channel toxin Tx1 (Precursor) OS=Buthus occitanus israelis PE=3 SV=1
33 : B8XH29_BUTOS 0.43 0.57 2 38 24 59 37 1 1 60 B8XH29 Putative potassium channel toxin Tx260 OS=Buthus occitanus israelis PE=3 SV=1
34 : KA157_ANDAM 0.43 0.59 2 38 24 59 37 1 1 59 Q5K0E0 Potassium channel toxin alpha-KTx 15.7 OS=Androctonus amoreuxi GN=tx1 PE=1 SV=1
35 : KAX32_LEIQH 1AGT 0.43 0.65 2 38 2 37 37 1 1 38 P46111 Potassium channel toxin alpha-KTx 3.2 OS=Leiurus quinquestriatus hebraeus PE=1 SV=1
36 : KAX33_LEIQH 0.43 0.65 2 38 2 37 37 1 1 38 P46112 Potassium channel toxin alpha-KTx 3.3 OS=Leiurus quinquestriatus hebraeus PE=1 SV=1
37 : KAX3A_BUTOS 0.43 0.57 2 38 24 59 37 1 1 59 P0C908 Potassium channel toxin alpha-KTx 3.10 OS=Buthus occitanus israelis PE=1 SV=1
## ALIGNMENTS 1 - 37
SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
1 1 A X 0 0 154 0 0
2 2 A I E +A 36 0A 27 23 14 I V I I VVVIIV VVV V VIVVVVVV
3 3 A D E +A 35 0A 87 25 79 D P T EDH EGESES PPG Q HYPPQPPP
4 4 A T E - 0 0A 43 35 47 TI TIII IILITIIIIITTIITIIITITTIITIII
5 5 A N E + 0 0A 97 35 15 NN NNNN NNDNDNNNNNNNNNDNNNNNNSNNNNNN
6 6 A V E - 0 0A 56 36 39 VV VVVVV VVIVIVVVVHKKVVVVVVVVIKVVKVVV
7 7 A K E -A 33 0A 153 38 32 KKRKPKKKKKKKSKKKKKRKKKKKKKKKKPEKKKSPK
8 8 A a + 0 0 38 38 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
9 9 A S S S- 0 0 88 37 73 SSNTNTTTTTSTRSTSKTG.STRRKRRQTRNRRKTTR
10 10 A G >> - 0 0 33 38 57 GLNGNSSGNSSgYSSGHGGQNSGGHGGGSGGGGGGGG
11 11 A S H 3> S+ 0 0 43 37 49 SPSSSPPSDPPaGSPSSSSGTPSSSSS.PTSSSGSSS
12 12 A S H 34 S+ 0 0 99 38 72 SQSQRKKPSQQDSSKPGHSGSKPPGKPGKSSRRSPPR
13 13 A K H <> S+ 0 0 107 38 58 KQEQPQQQDQQNDSQQQQESQQQQQEESQDEDDCQQD
14 14 A b H X S+ 0 0 2 38 5 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCACCC
15 15 A V H < S+ 0 0 47 38 68 VLILVLLLTLLLAYSLLIRAYLIILLLALYYLLSIIL
16 16 A K H > S+ 0 0 152 38 71 KRPKPKKKTRKQEEKKKKKSKLQQKPPSPESDDVKKD
17 17 A I H >X S+ 0 0 67 38 56 IPHPVPPPIPPPPPPPPPPVTPPPPAKVPPHPPCPPP
18 18 A c H 3X S+ 0 0 1 38 11 CCCCCCCCVCCCCCCCCCCCCCCCCCCCCCCCCACCC
19 19 A I H 34 S+ 0 0 88 38 61 IKIKIKKKIKKIKRKKKKAREKRKKKKRKEEKKKKKK
20 20 A D H << S+ 0 0 139 38 60 DDRDRDDDDDADRGEDDDRKKEDDDAERAKGKKEDDK
21 21 A R H < S- 0 0 83 38 82 RRIAELLASRAELVLAAAAVVIAAAAAEQKIAAIAAA
22 22 A Y S < S- 0 0 149 38 94 YFFGVYYGKFFYKTYGGGTIVYGGGVIIFYTGGGGGG
23 23 A N S S+ 0 0 137 38 79 NgGMNggMTggDCGgMMMGGGgMMMGGGgNGMMVMMM
24 24 A T - 0 0 3 24 93 ThT.Nhh.LhsTLRs...YVVh...KKVsCK......
25 25 A R S S+ 0 0 151 38 80 RARRKAARTAATLAARRRYAAARRRASAAARRRARRR
26 26 A G + 0 0 17 38 96 GGAFNGGFGGGKPHGFFFSAAGFFFAAAGRSFFAFFF
27 27 A A E -B 36 0A 12 38 38 AGAGGAAGRGGTSGAGGGSGGAGGGGGGAAGGGGGGG
28 28 A K E -B 35 0A 116 38 0 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
29 29 A a E +B 34 0A 31 38 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
30 30 A I S S+ 0 0 96 38 36 IIIMSMMIIIIIIMMMIIIIMMMMMMMIMMIIIIMMI
31 31 A N S S- 0 0 105 38 0 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
32 32 A G S S+ 0 0 42 38 47 GGRGGGGGGGGDGGGRGRGGGGGGGGGGGRKSSGRRS
33 33 A R E S-A 7 0A 56 38 32 RKKKKKKKVKKRKRKKKKSRKKKKKKKKKHKKKRKKK
34 34 A b E - B 0 29A 4 38 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
35 35 A T E -AB 3 28A 10 38 91 TKYHLKKHSKKNTTKHDHVVIKHHDKKVKNYHHVHHH
36 36 A c E -AB 2 27A 0 38 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
37 37 A Y 0 0 100 37 61 YYYTYYYT YYYYYYTTTYYYYTTTYYYYYYTTYTTT
38 38 A P 0 0 98 28 0 PPPPP P PPPP PPP PP PPPPP P PPPPPP
## SEQUENCE PROFILE AND ENTROPY
SeqNo PDBNo V L I M F W Y G A P S T C H R K Q E N D NOCC NDEL NINS ENTROPY RELENT WEIGHT
1 1 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.000 0 1.00
2 2 A 70 0 30 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23 0 0 0.615 20 0.86
3 3 A 0 0 0 0 0 0 4 8 0 32 8 4 0 8 0 0 8 16 0 12 25 0 0 1.978 66 0.21
4 4 A 0 3 66 0 0 0 0 0 0 0 0 31 0 0 0 0 0 0 0 0 35 0 0 0.741 24 0.52
5 5 A 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 89 9 35 0 0 0.420 14 0.85
6 6 A 78 0 8 0 0 0 0 0 0 0 0 0 0 3 0 11 0 0 0 0 36 0 0 0.746 24 0.60
7 7 A 0 0 0 0 0 0 0 0 0 8 5 0 0 0 5 79 0 3 0 0 38 0 0 0.793 26 0.67
8 8 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 38 1 0 0.000 0 1.00
9 9 A 0 0 0 0 0 0 0 3 0 0 19 35 0 0 24 8 3 0 8 0 37 0 0 1.629 54 0.27
10 10 A 0 3 0 0 0 0 3 55 0 0 21 0 0 5 0 0 3 0 11 0 38 1 1 1.335 44 0.43
11 11 A 0 0 0 0 0 0 0 8 3 22 59 5 0 0 0 0 0 0 0 3 37 0 0 1.197 39 0.50
12 12 A 0 0 0 0 0 0 0 11 0 18 29 0 0 3 11 16 11 0 0 3 38 0 0 1.864 62 0.27
13 13 A 0 0 0 0 0 0 0 0 0 3 8 0 3 0 0 5 50 13 3 16 38 0 0 1.547 51 0.41
14 14 A 0 0 0 0 0 0 0 0 3 0 0 0 97 0 0 0 0 0 0 0 38 0 0 0.122 4 0.95
15 15 A 8 47 16 0 0 0 11 0 8 0 5 3 0 0 3 0 0 0 0 0 38 0 0 1.630 54 0.31
16 16 A 3 3 0 0 0 0 0 0 0 13 8 3 0 0 5 42 8 8 0 8 38 0 0 1.875 62 0.28
17 17 A 8 0 8 0 0 0 0 0 3 68 0 3 3 5 0 3 0 0 0 0 38 0 0 1.198 40 0.44
18 18 A 3 0 0 0 0 0 0 0 3 0 0 0 95 0 0 0 0 0 0 0 38 0 0 0.243 8 0.89
19 19 A 0 0 16 0 0 0 0 0 3 0 0 0 0 0 11 63 0 8 0 0 38 0 0 1.115 37 0.39
20 20 A 0 0 0 0 0 0 0 5 8 0 0 0 0 0 13 16 0 11 0 47 38 0 0 1.505 50 0.40
21 21 A 8 11 11 0 0 0 0 0 45 0 3 0 0 0 11 3 3 8 0 0 38 0 0 1.759 58 0.18
22 22 A 8 0 8 0 13 0 21 37 0 0 0 8 0 0 0 5 0 0 0 0 38 0 0 1.719 57 0.06
23 23 A 3 0 0 34 0 0 0 45 0 0 0 3 3 0 0 0 0 0 11 3 38 14 8 1.347 44 0.20
24 24 A 13 8 0 0 0 0 4 0 0 0 13 17 4 21 4 13 0 0 4 0 24 0 0 2.142 71 0.06
25 25 A 0 3 0 0 0 0 3 0 39 0 3 5 0 0 45 3 0 0 0 0 38 0 0 1.265 42 0.20
26 26 A 0 0 0 0 34 0 0 29 18 3 5 0 0 3 3 3 0 0 3 0 38 0 0 1.671 55 0.04
27 27 A 0 0 0 0 0 0 0 66 24 0 5 3 0 0 3 0 0 0 0 0 38 0 0 0.963 32 0.62
28 28 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 38 0 0 0.000 0 1.00
29 29 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 38 0 0 0.000 0 1.00
30 30 A 0 0 53 45 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 38 0 0 0.793 26 0.63
31 31 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 38 0 0 0.000 0 1.00
32 32 A 0 0 0 0 0 0 0 71 0 0 8 0 0 0 16 3 0 0 0 3 38 0 0 0.926 30 0.53
33 33 A 3 0 0 0 0 0 0 0 0 0 3 0 0 3 16 76 0 0 0 0 38 0 0 0.785 26 0.68
34 34 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 38 0 0 0.000 0 1.00
35 35 A 11 3 3 0 0 0 5 0 0 0 3 11 0 29 0 26 0 0 5 5 38 0 0 1.936 64 0.09
36 36 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 38 0 0 0.000 0 1.00
37 37 A 0 0 0 0 0 0 65 0 0 0 0 35 0 0 0 0 0 0 0 0 37 0 0 0.648 21 0.38
38 38 A 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 28 0 0 0.000 0 1.00
## INSERTION LIST
AliNo IPOS JPOS Len Sequence
2 21 23 1 gQh
6 21 23 1 gPh
7 21 23 1 gPh
10 23 23 1 gQh
11 21 23 1 gIs
12 9 33 1 gGa
15 21 23 1 gSs
22 21 23 1 gIh
29 21 23 1 gQs
//