Complet list of 1z87 hssp file
Complete list of 1z87.hssp file
HSSP HOMOLOGY DERIVED SECONDARY STRUCTURE OF PROTEINS , VERSION 2.0 2011
PDBID 1Z87
THRESHOLD according to: t(L)=(290.15 * L ** -0.562) + 5
REFERENCE Sander C., Schneider R. : Database of homology-derived protein structures. Proteins, 9:56-68 (1991).
CONTACT Maintained at http://www.cmbi.ru.nl/ by Maarten L. Hekkelman
DATE file generated on 2014-05-14
HEADER PROTEIN BINDING 30-MAR-05 1Z87
COMPND MOL_ID: 1; MOLECULE: ALPHA-1-SYNTROPHIN; CHAIN: A; FRAGMENT: THE PHN-P
SOURCE MOL_ID: 1; ORGANISM_SCIENTIFIC: MUS MUSCULUS; ORGANISM_COMMON: HOUSE M
AUTHOR J.YAN,W.XU,W.WEN,J.F.LONG,M.E.ADAMS,S.C.FROEHNER,M.ZHANG
DBREF 1Z87 A 2 264 UNP Q61234 SNA1_MOUSE 2 264
SEQLENGTH 263
NCHAIN 1 chain(s) in 1Z87 data set
NALIGN 83
NOTATION : ID: EMBL/SWISSPROT identifier of the aligned (homologous) protein
NOTATION : STRID: if the 3-D structure of the aligned protein is known, then STRID is the Protein Data Bank identifier as taken
NOTATION : from the database reference or DR-line of the EMBL/SWISSPROT entry
NOTATION : %IDE: percentage of residue identity of the alignment
NOTATION : %SIM (%WSIM): (weighted) similarity of the alignment
NOTATION : IFIR/ILAS: first and last residue of the alignment in the test sequence
NOTATION : JFIR/JLAS: first and last residue of the alignment in the alignend protein
NOTATION : LALI: length of the alignment excluding insertions and deletions
NOTATION : NGAP: number of insertions and deletions in the alignment
NOTATION : LGAP: total length of all insertions and deletions
NOTATION : LSEQ2: length of the entire sequence of the aligned protein
NOTATION : ACCNUM: SwissProt accession number
NOTATION : PROTEIN: one-line description of aligned protein
NOTATION : SeqNo,PDBNo,AA,STRUCTURE,BP1,BP2,ACC: sequential and PDB residue numbers, amino acid (lower case = Cys), secondary
NOTATION : structure, bridge partners, solvent exposure as in DSSP (Kabsch and Sander, Biopolymers 22, 2577-2637(1983)
NOTATION : VAR: sequence variability on a scale of 0-100 as derived from the NALIGN alignments
NOTATION : pair of lower case characters (AvaK) in the alignend sequence bracket a point of insertion in this sequence
NOTATION : dots (....) in the alignend sequence indicate points of deletion in this sequence
NOTATION : SEQUENCE PROFILE: relative frequency of an amino acid type at each position. Asx and Glx are in their
NOTATION : acid/amide form in proportion to their database frequencies
NOTATION : NOCC: number of aligned sequences spanning this position (including the test sequence)
NOTATION : NDEL: number of sequences with a deletion in the test protein at this position
NOTATION : NINS: number of sequences with an insertion in the test protein at this position
NOTATION : ENTROPY: entropy measure of sequence variability at this position
NOTATION : RELENT: relative entropy, i.e. entropy normalized to the range 0-100
NOTATION : WEIGHT: conservation weight
## PROTEINS : identifier and alignment statistics
NR. ID STRID %IDE %WSIM IFIR ILAS JFIR JLAS LALI NGAP LGAP LSEQ2 ACCNUM PROTEIN
1 : A2AKD7_MOUSE 1.00 1.00 1 263 2 264 263 0 0 499 A2AKD7 Alpha-1-syntrophin OS=Mus musculus GN=Snta1 PE=2 SV=1
2 : Q3UVD6_MOUSE 1.00 1.00 1 263 2 264 263 0 0 499 Q3UVD6 Putative uncharacterized protein OS=Mus musculus GN=Snta1 PE=2 SV=1
3 : SNTA1_MOUSE 2ADZ 1.00 1.00 1 263 2 264 263 0 0 503 Q61234 Alpha-1-syntrophin OS=Mus musculus GN=Snta1 PE=1 SV=1
4 : B5DFL0_RAT 0.97 1.00 1 263 2 264 263 0 0 499 B5DFL0 Protein Snta1 OS=Rattus norvegicus GN=Snta1 PE=2 SV=1
5 : G1RG04_NOMLE 0.93 0.96 1 263 2 270 269 1 6 505 G1RG04 Uncharacterized protein OS=Nomascus leucogenys GN=SNTA1 PE=4 SV=1
6 : G1T281_RABIT 0.93 0.96 1 263 2 270 269 1 6 488 G1T281 Alpha-1-syntrophin OS=Oryctolagus cuniculus GN=SNTA1 PE=4 SV=1
7 : SNTA1_RABIT 0.93 0.96 1 263 2 270 269 1 6 505 Q28626 Alpha-1-syntrophin OS=Oryctolagus cuniculus GN=SNTA1 PE=1 SV=1
8 : G5BPU9_HETGA 0.92 0.96 1 263 2 270 269 1 6 505 G5BPU9 Alpha-1-syntrophin OS=Heterocephalus glaber GN=GW7_12305 PE=4 SV=1
9 : G7N521_MACMU 0.92 0.99 57 263 2 208 207 0 0 443 G7N521 59 kDa dystrophin-associated protein A1 acidic component 1 OS=Macaca mulatta GN=EGK_02501 PE=4 SV=1
10 : H0XR08_OTOGA 0.92 0.95 1 263 2 270 269 1 6 509 H0XR08 Uncharacterized protein OS=Otolemur garnettii GN=SNTA1 PE=4 SV=1
11 : H0XZ60_OTOGA 0.92 0.95 1 263 2 270 269 1 6 505 H0XZ60 Uncharacterized protein OS=Otolemur garnettii GN=SNTA1 PE=4 SV=1
12 : H2P1N7_PONAB 0.92 0.96 1 263 2 270 269 1 6 505 H2P1N7 Uncharacterized protein OS=Pongo abelii GN=SNTA1 PE=4 SV=1
13 : B4DX40_HUMAN 0.91 0.96 1 248 2 255 254 1 6 430 B4DX40 cDNA FLJ56556, highly similar to Alpha-1-syntrophin OS=Homo sapiens PE=2 SV=1
14 : F6WZA9_CALJA 0.91 0.96 1 248 2 255 254 1 6 430 F6WZA9 Uncharacterized protein OS=Callithrix jacchus GN=SNTA1 PE=4 SV=1
15 : G3QZK5_GORGO 0.91 0.95 1 263 2 270 269 1 6 505 G3QZK5 Uncharacterized protein OS=Gorilla gorilla gorilla GN=101135197 PE=4 SV=1
16 : H0V4V4_CAVPO 0.91 0.96 1 263 2 270 269 1 6 505 H0V4V4 Uncharacterized protein OS=Cavia porcellus GN=SNTA1 PE=4 SV=1
17 : H2QK69_PANTR 0.91 0.95 1 263 2 270 269 1 6 505 H2QK69 Syntrophin, alpha 1 (Dystrophin-associated protein A1, 59kDa, acidic component) OS=Pan troglodytes GN=SNTA1 PE=2 SV=1
18 : L5JYF6_PTEAL 0.91 0.94 24 263 70 315 246 1 6 550 L5JYF6 Alpha-1-syntrophin OS=Pteropus alecto GN=PAL_GLEAN10024233 PE=4 SV=1
19 : M3Z2A9_MUSPF 0.91 0.96 1 263 2 270 269 1 6 505 M3Z2A9 Uncharacterized protein OS=Mustela putorius furo GN=SNTA1 PE=4 SV=1
20 : SNTA1_HUMAN 0.91 0.95 1 263 2 270 269 1 6 505 Q13424 Alpha-1-syntrophin OS=Homo sapiens GN=SNTA1 PE=1 SV=1
21 : U3EA51_CALJA 0.91 0.96 1 263 2 270 269 1 6 505 U3EA51 Alpha-1-syntrophin OS=Callithrix jacchus GN=SNTA1 PE=2 SV=1
22 : U3EU55_CALJA 0.91 0.96 1 263 2 270 269 1 6 505 U3EU55 Alpha-1-syntrophin OS=Callithrix jacchus GN=SNTA1 PE=2 SV=1
23 : U3F9T2_CALJA 0.91 0.96 1 263 2 270 269 1 6 505 U3F9T2 Alpha-1-syntrophin OS=Callithrix jacchus GN=SNTA1 PE=2 SV=1
24 : F7DF22_MACMU 0.90 0.96 1 263 2 270 269 1 6 505 F7DF22 Alpha-1-syntrophin OS=Macaca mulatta GN=SNTA1 PE=2 SV=1
25 : I2CXI7_MACMU 0.90 0.96 1 263 2 270 269 1 6 505 I2CXI7 Alpha-1-syntrophin OS=Macaca mulatta GN=SNTA1 PE=2 SV=1
26 : W5PD91_SHEEP 0.90 0.94 1 263 95 363 269 1 6 598 W5PD91 Uncharacterized protein OS=Ovis aries GN=SNTA1 PE=4 SV=1
27 : SNTA1_BOVIN 0.89 0.94 1 263 2 270 269 1 6 505 Q0P5E6 Alpha-1-syntrophin OS=Bos taurus GN=SNTA1 PE=2 SV=1
28 : F1S4Z9_PIG 0.88 0.94 1 263 2 270 269 1 6 505 F1S4Z9 Uncharacterized protein OS=Sus scrofa GN=SNTA1 PE=4 SV=1
29 : G3U925_LOXAF 0.88 0.96 47 263 1 223 223 1 6 458 G3U925 Uncharacterized protein (Fragment) OS=Loxodonta africana GN=SNTA1 PE=4 SV=1
30 : F6XM17_CALJA 0.87 0.92 1 258 2 253 264 3 18 491 F6XM17 Uncharacterized protein OS=Callithrix jacchus GN=SNTA1 PE=4 SV=1
31 : G3RXR0_GORGO 0.87 0.91 1 263 2 259 269 2 17 494 G3RXR0 Uncharacterized protein OS=Gorilla gorilla gorilla GN=101135197 PE=4 SV=1
32 : L9L495_TUPCH 0.69 0.77 57 263 1 228 230 3 25 463 L9L495 Alpha-1-syntrophin OS=Tupaia chinensis GN=TREES_T100008616 PE=4 SV=1
33 : G1KHX2_ANOCA 0.62 0.82 25 263 115 357 248 4 14 592 G1KHX2 Uncharacterized protein OS=Anolis carolinensis GN=SNTA1 PE=4 SV=2
34 : J3S582_CROAD 0.62 0.79 27 262 22 254 242 4 15 490 J3S582 Alpha-1-syntrophin-like OS=Crotalus adamanteus PE=2 SV=1
35 : T1DKT5_CROHD 0.62 0.79 27 262 22 254 242 4 15 490 T1DKT5 Alpha-1-syntrophin-like protein OS=Crotalus horridus PE=2 SV=1
36 : F6SZH6_XENTR 0.60 0.77 26 263 21 245 238 6 13 472 F6SZH6 Uncharacterized protein OS=Xenopus tropicalis GN=snta1 PE=4 SV=1
37 : F6PP33_MONDO 0.59 0.76 1 262 2 271 277 3 22 507 F6PP33 Uncharacterized protein OS=Monodelphis domestica GN=SNTA1 PE=4 SV=2
38 : H3AS46_LATCH 0.59 0.78 27 263 22 246 238 5 14 481 H3AS46 Uncharacterized protein OS=Latimeria chalumnae PE=4 SV=1
39 : V8PAD3_OPHHA 0.58 0.75 25 262 20 270 258 4 27 524 V8PAD3 Alpha-1-syntrophin (Fragment) OS=Ophiophagus hannah GN=SNTA1 PE=4 SV=1
40 : F7BBF2_XENTR 0.57 0.75 26 263 21 246 239 5 14 475 F7BBF2 Uncharacterized protein OS=Xenopus tropicalis GN=snta1 PE=4 SV=1
41 : Q05AR3_XENTR 0.57 0.75 26 263 21 245 241 5 19 473 Q05AR3 Uncharacterized protein OS=Xenopus tropicalis GN=snta1 PE=2 SV=1
42 : H2LN83_ORYLA 0.56 0.73 27 263 22 259 243 4 11 493 H2LN83 Uncharacterized protein OS=Oryzias latipes PE=4 SV=1
43 : Q5M998_XENLA 0.56 0.74 26 263 21 245 242 4 21 473 Q5M998 LOC496157 protein OS=Xenopus laevis GN=snta1 PE=2 SV=1
44 : H2U2L9_TAKRU 0.55 0.74 27 263 22 258 243 5 12 487 H2U2L9 Uncharacterized protein OS=Takifugu rubripes GN=LOC101064267 PE=4 SV=1
45 : Q91492_TORCA 0.53 0.73 26 263 19 252 241 3 10 488 Q91492 Syntrophin OS=Torpedo californica PE=2 SV=1
46 : W5K043_ASTMX 0.53 0.70 27 263 22 254 243 4 16 473 W5K043 Uncharacterized protein OS=Astyanax mexicanus GN=SNTA1 PE=4 SV=1
47 : E6ZF54_DICLA 0.52 0.71 27 263 22 258 249 5 24 487 E6ZF54 Alpha-1-syntrophin OS=Dicentrarchus labrax GN=SNTA1 PE=4 SV=1
48 : H3CNK0_TETNG 0.52 0.72 27 263 22 258 249 5 24 487 H3CNK0 Uncharacterized protein OS=Tetraodon nigroviridis GN=SNTA1 PE=4 SV=1
49 : I3JI75_ORENI 0.52 0.71 27 263 22 258 249 5 24 487 I3JI75 Uncharacterized protein OS=Oreochromis niloticus GN=SNTA1 PE=4 SV=1
50 : W5U756_ICTPU 0.51 0.70 27 259 22 250 244 4 26 480 W5U756 Alpha-1-syntrophin OS=Ictalurus punctatus GN=SNTA1 PE=2 SV=1
51 : E7FDB9_DANRE 0.48 0.70 27 263 22 253 248 4 27 404 E7FDB9 Uncharacterized protein OS=Danio rerio GN=LOC100332905 PE=4 SV=1
52 : H0V6C3_CAVPO 0.47 0.68 26 263 32 290 262 4 27 529 H0V6C3 Uncharacterized protein (Fragment) OS=Cavia porcellus GN=SNTB1 PE=4 SV=1
53 : D3ZWC6_RAT 0.46 0.66 26 263 34 300 267 4 29 539 D3ZWC6 Protein Sntb1 OS=Rattus norvegicus GN=Sntb1 PE=4 SV=1
54 : F1PS17_CANFA 0.46 0.68 26 263 32 291 262 4 26 530 F1PS17 Uncharacterized protein OS=Canis familiaris GN=SNTB1 PE=4 SV=2
55 : M3XPV9_MUSPF 0.46 0.70 26 263 33 293 261 2 23 329 M3XPV9 Uncharacterized protein OS=Mustela putorius furo GN=SNTB1 PE=4 SV=1
56 : SNTB1_MOUSE 0.46 0.66 26 263 32 298 267 4 29 537 Q99L88 Beta-1-syntrophin OS=Mus musculus GN=Sntb1 PE=1 SV=4
57 : F7H9E4_MACMU 0.45 0.66 26 263 31 297 267 4 29 377 F7H9E4 Uncharacterized protein (Fragment) OS=Macaca mulatta GN=SNTB1 PE=4 SV=1
58 : G1QZA2_NOMLE 0.45 0.66 26 263 33 299 267 4 29 538 G1QZA2 Uncharacterized protein OS=Nomascus leucogenys GN=SNTB1 PE=4 SV=1
59 : G1TB55_RABIT 0.45 0.66 27 263 36 301 266 4 29 540 G1TB55 Uncharacterized protein OS=Oryctolagus cuniculus GN=SNTB1 PE=4 SV=2
60 : G3R3B9_GORGO 0.45 0.67 26 263 33 299 267 4 29 538 G3R3B9 Uncharacterized protein OS=Gorilla gorilla gorilla GN=101141662 PE=4 SV=1
61 : H0XMH5_OTOGA 0.45 0.66 27 263 30 295 266 4 29 534 H0XMH5 Uncharacterized protein (Fragment) OS=Otolemur garnettii GN=SNTB1 PE=4 SV=1
62 : H2PR40_PONAB 0.45 0.67 26 263 33 299 267 4 29 538 H2PR40 Uncharacterized protein OS=Pongo abelii GN=SNTB1 PE=4 SV=1
63 : H2QWN2_PANTR 0.45 0.67 26 263 33 299 267 4 29 538 H2QWN2 Syntrophin, beta 1 (Dystrophin-associated protein A1, 59kDa, basic component 1) OS=Pan troglodytes GN=SNTB1 PE=2 SV=1
64 : K9IT08_DESRO 0.45 0.67 26 263 22 289 268 4 30 528 K9IT08 Putative syntrophins type beta (Fragment) OS=Desmodus rotundus PE=2 SV=1
65 : SNTB1_HUMAN 0.45 0.67 26 263 33 299 267 4 29 538 Q13884 Beta-1-syntrophin OS=Homo sapiens GN=SNTB1 PE=1 SV=3
66 : U3BJ13_CALJA 0.45 0.67 26 263 34 300 267 4 29 539 U3BJ13 Beta-1-syntrophin OS=Callithrix jacchus GN=SNTB1 PE=2 SV=1
67 : U3E7R8_CALJA 0.45 0.67 26 263 34 300 267 4 29 539 U3E7R8 Beta-1-syntrophin OS=Callithrix jacchus GN=SNTB1 PE=2 SV=1
68 : V9KM37_CALMI 0.45 0.65 15 263 4 286 283 3 34 518 V9KM37 Syntrophin (Fragment) OS=Callorhynchus milii PE=2 SV=1
69 : V9LDV0_CALMI 0.45 0.68 45 262 1 229 229 2 11 249 V9LDV0 Beta-1-syntrophin (Fragment) OS=Callorhynchus milii PE=2 SV=1
70 : H9F7Z8_MACMU 0.44 0.66 25 263 3 270 268 4 29 509 H9F7Z8 Beta-1-syntrophin (Fragment) OS=Macaca mulatta GN=SNTB1 PE=2 SV=1
71 : Q4SSA8_TETNG 0.44 0.61 27 263 22 300 291 6 66 531 Q4SSA8 Chromosome 11 SCAF14479, whole genome shotgun sequence OS=Tetraodon nigroviridis GN=GSTENG00013519001 PE=4 SV=1
72 : G3NBS5_GASAC 0.43 0.63 30 263 36 301 266 4 32 540 G3NBS5 Uncharacterized protein (Fragment) OS=Gasterosteus aculeatus GN=SNTB2 PE=4 SV=1
73 : H3B930_LATCH 0.43 0.66 27 263 25 282 261 4 27 521 H3B930 Uncharacterized protein OS=Latimeria chalumnae PE=4 SV=2
74 : Q5ZKZ8_CHICK 0.43 0.64 27 263 29 284 259 4 25 523 Q5ZKZ8 Uncharacterized protein OS=Gallus gallus GN=SNTB1 PE=2 SV=1
75 : Q6GMG2_DANRE 0.42 0.64 27 263 22 277 264 4 35 515 Q6GMG2 Uncharacterized protein OS=Danio rerio GN=sntb1 PE=2 SV=1
76 : F7CVW1_MONDO 0.41 0.60 26 263 42 332 291 3 53 571 F7CVW1 Uncharacterized protein OS=Monodelphis domestica GN=SNTB1 PE=4 SV=2
77 : G3NV17_GASAC 0.41 0.63 27 259 32 288 263 4 36 532 G3NV17 Uncharacterized protein (Fragment) OS=Gasterosteus aculeatus PE=4 SV=1
78 : G3NV28_GASAC 0.41 0.62 27 259 29 301 279 3 52 556 G3NV28 Uncharacterized protein OS=Gasterosteus aculeatus PE=4 SV=1
79 : H2S1N6_TAKRU 0.39 0.56 29 263 25 302 288 4 63 543 H2S1N6 Uncharacterized protein (Fragment) OS=Takifugu rubripes PE=4 SV=1
80 : D3ZMX6_RAT 0.38 0.62 27 261 21 281 265 4 34 522 D3ZMX6 Protein Sntb2 OS=Rattus norvegicus GN=Sntb2 PE=4 SV=2
81 : B4IYV9_DROGR 0.34 0.58 1 263 69 358 298 4 43 640 B4IYV9 GH15089 OS=Drosophila grimshawi GN=Dgri\GH15089 PE=4 SV=1
82 : T1G972_HELRO 0.34 0.52 24 262 11 290 295 5 71 546 T1G972 Uncharacterized protein OS=Helobdella robusta GN=HELRODRAFT_95740 PE=4 SV=1
83 : W8BKF2_CERCA 0.33 0.55 15 261 40 349 310 5 63 638 W8BKF2 Beta-1-syntrophin OS=Ceratitis capitata GN=SNTB1 PE=2 SV=1
## ALIGNMENTS 1 - 70
SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
1 2 A A 0 0 159 31 23 AAAAAAAA AAAAAAAA AAAAAAAAAA AA A
2 3 A S + 0 0 127 31 41 SSSSSSSS SSSSSSSS SSSSSSSSSS SS A
3 4 A G - 0 0 61 31 2 GGGGGGGG GGSGGGGG GGGGGGGGGG GG G
4 5 A R S S+ 0 0 234 31 23 RRRRRRRR RRRRRRRR RRRRRRRRRR RR R
5 6 A R - 0 0 177 31 30 RRRRRRRR RRRRRRRR RRRRRRRRRR RR R
6 7 A A - 0 0 78 31 39 AAAAAAAA AAAAAAAA SAAAAAAAAA AA S
7 8 A P - 0 0 65 31 25 PPPPPPPP PPPPPPPP PPPPPPPPPP PP P
8 9 A R E -A 34 0A 146 31 49 RRRRRRRR RRRRRRRR RRRRRRRRRR RR K
9 10 A T E +A 33 0A 81 31 45 TTTTTTTT TTTTTTNT TTTTTTTTTT TT S
10 11 A G E -A 32 0A 16 31 0 GGGGGGGG GGGGGGGG GGGGGGGGGG GG G
11 12 A L E +A 31 0A 82 31 34 LLLLLLLL LLLLLLLL LLLLLLLLLL LL L
12 13 A L E -A 30 0A 5 31 0 LLLLLLLL LLLLLLLL LLLLLLLLLL LL L
13 14 A E E -AB 29 243A 73 31 21 EEEEEEEE EEEEEEEE EEEEEEEEEE EE E
14 15 A L E -AB 28 242A 17 30 41 LLLLLLLL LLLLLLLL LLLLLLLLLL .L L
15 16 A R E -A 27 0A 58 32 23 RRRRRRRS RRRRRRRR RRRRRRRRRR .R R R
16 17 A C + 0 0 59 32 57 CCCSAAAA AAAAAAAA AAAAAAAAAA .A A S
17 18 A G S > S+ 0 0 72 32 23 GGGGGGGG GGGGGGGG GGGGGGGGGG .G P G
18 19 A A T 3 + 0 0 24 32 54 AAAAATTA AAAAAAAA AAAAAAAAAA .A G L
19 20 A G T 3 S- 0 0 73 32 57 GGGGGGGG GGGGGGGG GGGGGGGGGG .G S L
20 21 A S S < S+ 0 0 129 32 55 SSSSSAAS SSSSSSSS SSSSSSSSSS .S A E
21 22 A G - 0 0 63 32 24 GGGGGGGG GGGGGGGG GGGGGGGGGG .G G A
22 23 A A + 0 0 88 32 56 AAAAAAAA AAAAAAAA AAAAATTAAA .A P L
23 24 A G S S+ 0 0 82 32 39 GGGGGGGG GGGGGGGG GGGGGGGGGG .G G S
24 25 A G S S- 0 0 53 34 44 GGGGGGGG GGGGGGGGGGGGGGGGGGG .G P G
25 26 A E - 0 0 113 38 46 EEEEEEEE EEEEEEEEEEEEEEEEEEE QE E W E D D
26 27 A R - 0 0 167 58 30 RRRRRRRR RRRRRRRRRRRRRRRRRRR RR Q RL QRR R R RRRRRRR R RRRRRRR R
27 28 A W E +A 15 0A 75 78 5 WWWWWWWW WWWWWWWWWWWWWWWWWWW WW WWWWRWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWW W
28 29 A Q E -A 14 0A 69 78 80 QQQQQQQQ QQQQQQHQQQQQQQQQQQQ QQ LLLVVVLVVVLRRSIMISIHHHHHHHHHHHHHHHHL H
29 30 A R E +A 13 0A 163 79 33 RRRRRRRR RRRRRRRRRRRRRRRRRRR RR RRRRLRRRRRRRRRRRRRRKKKKKKKKKKKKKKKKR K
30 31 A V E -A 12 0A 21 80 9 VVVVVVVV IIVVVVVVVVVVVVVVMAV VV VVVVVVVVVVVVLVVVVVVVVVVVVVVVVVVVVVVV V
31 32 A L E -AC 11 42A 47 80 19 LLLLLLLL LLLLLLLLLLLLLLLLLVL LL LLLLSLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL L
32 33 A L E -AC 10 41A 1 80 59 LLLLLVVL LLLLLLLLLLLLLLLLLLL LL LVVLLAVLLALAAAAAAAAVVVVVVVVVVVVVVVVV V
33 34 A S E -AC 9 40A 19 80 72 SSSTSSSS SSSSSSSSSSSSSSSSSSS SS ATTLASTLLTLTSATTTTTNNNNNNNNNNNNNNNNS N
34 35 A L E +AC 8 39A 7 80 3 LLLLLLLL LLLLLLLLLLLLLLLLLLL LL LLLLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL L
35 36 A A - 0 0 45 80 66 AAAAAAAA AAAAAAAAAAAAAAAAEEA AA SSSGDTSGGTGTSTTTTSTGSGSSSSSSSSSSSSST S
36 37 A E S S+ 0 0 99 80 29 EEEEEEEE EEEEEEEEEEEEEEEEEEE EE EEEEVEEEEEEEEGEEEAGEEEEEEEEEEEEEEEEA E
37 38 A D S S+ 0 0 73 80 21 DDDDDDDD DDDDDDDDDDDDDDDDDDD DD DDDEVEDEEDEDDDDDDDDDDDDDDDDDDDDDDDDA D
38 39 A A E - D 0 209A 28 80 69 AAAAVAAA MMVVVVAVAAVVVVVVAAT VV FFFTTTFTTATTAATTSTTAAAAAAAAAAAAAAAAN A
39 40 A L E -CD 34 208A 0 80 7 LLLLLLLL LLLLLLLLLLLLLLLLLLL LL LLLVVLLVVLLLLLLLLLFLLLLLLLLLLLLLLLLL L
40 41 A T E -CD 33 207A 47 80 62 TTTTTTTT TTTTTTTTTTTTTTTTTTT TT SSSTSSSTTTSTCTTTTTTVVVVVVVVIVVVVVVVQ V
41 42 A V E +CD 32 206A 7 80 38 VVVVVVVV VVVVVVVVVVVVVVVVVVV VV VVVFAVVFFLFVLVLVLLVLLLLLLLLLLLLLLLLL L
42 43 A S E -C 31 0A 45 80 37 SSSSSSSS SSSSSSSSSSSSSSSSSSS SS SIITASVTTNTNSSNNNSSSSSSSSSSSSSSSSSSS S
43 44 A P - 0 0 80 80 59 PPPPPPPP PPPPSPPPPPPSSSPPPPP SP PPPPPPPPPPPPPPPPPPPGCCCCSSCSCSSCSSSP S
44 45 A A - 0 0 36 80 61 ATAAAAAA AAAAAAAAAAAAAAAAAAA AA GSSEAGSEEGESAAGGGGGEEEEEEEEEEEEEEEEE E
45 46 A D - 0 0 130 81 42 DDDDDDDD DDDDDDDDDDDDDDDDDDD DD GTTPSEAPPDPEGEEEEEEDEEEEEEEEEEEEEEEEQE
46 47 A G + 0 0 67 81 43 GGGGGGGG GGGGGGGGGGGGGGGGGGG GG gkkEgGkEEsEaGAgagvtggggggggggggggggpGg
47 48 A E S S- 0 0 156 76 74 EEEEDEEE EEDDDDEDEEDDDDDDEEEEDD gqq.v.l..k.kA.kkkksasaasaaaataataaagVa
48 49 A P + 0 0 130 80 65 PPPPPPPP PPPPPPPPPIPPPPPPPPPSPP KPPPS.NPPPPAG.PAPSNGGGGGGGGGGGGGGGGRGG
49 50 A G + 0 0 65 82 49 GGGGGGGG GGGGGGGGGGGGGGGGGGGGGG GPPGAAGGGGGAGSNANASPTGGTAAAAAAAHAAASSA
50 51 A P S S- 0 0 129 82 59 PPPPPPPP PPPPPPPPQPPPPPPPPPPPPP PPPASPAAAHAPPEPPPPPPGAAGGGGGGGGPGGGGRG
51 52 A E - 0 0 133 82 70 EEEEEEEE EEEEDEEEEEEDDDEEEEEDDE ESSALEEAAQATAENTSAAEHQQHHHHHHHHGHHHSSH
52 53 A P S S+ 0 0 123 82 47 PPPPpppp ppppppppppppppsspppppp ePPEpvaEESePlpppptpSppPptppppppapppppt
53 54 A E S S+ 0 0 155 73 70 EEEEeeee eeeeeeeeeeeeeeeeeeveee s...gss..Pn.gaddded.asPappppppppppptap
54 55 A P - 0 0 87 80 40 PPPPPPPS PPPPPPSPPPPPPPPPPPPPPP P..EAPPEEAGVEPPPPPPPPPDPPPPPPPPPPPPPAP
55 56 A A - 0 0 75 82 68 AAAAAAAA AAAAAAAAAAAAAAAAAAAAAA GVVKDRVKKGAGPAPPPGAADASDDDDDDDDDDDDCAD
56 57 A Q - 0 0 117 82 77 QQQQQQQQ QQQQQQQQQQQQQQQQQQQQQQ QQQAPVQAAAEAEPNNNHNGSGPSSSSSSSSSSSSPAS
57 58 A L - 0 0 171 84 65 LLLLLLILLLLLLLLLLLLLLLLLLLLLLLLMLLLLGLLLLVLLLLLLLLLVPVAPPPPPPPPPPPPAAP
58 59 A N S S+ 0 0 102 84 69 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKTNNNNANNNNNTNENSSSSSRARGAAAAAAAAAAAAPSA
59 60 A G + 0 0 40 83 39 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGG.QGGGGPGGGGGGGTGSSSSATgTVggggggggggggGPg
60 61 A A S S+ 0 0 83 52 94 AAAAAAAAAAAAAAAAASAAAAAAAAAAAA......A...............r.RrrrrrrrrrrrrSRr
61 62 A A - 0 0 33 55 65 AAAAAAAAAAAAAAAAAAAAAAAAAAATAA......A....D.D.E......T.TTTTTTTTTTTTTPNT
62 63 A E S S+ 0 0 192 60 70 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEE.H....P....P.P.P.....AAAAAAAAAAAAAAAACAA
63 64 A P S S+ 0 0 103 61 108 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPP.VG...G....P.P.S.....FFFFFFFFFFFFFFFFPSF
64 65 A G S S- 0 0 78 68 69 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGG.EDAAAA.AAAN.N.S.....TTTTTTTTTTTTTTTTAAT
65 66 A A S S+ 0 0 51 69 76 AAAAAAAAAIIAAAAAATAAAAAAAAAAAA.SPEEEPDEEEL.L.L.....DDDDDDDDDDDDDDDDPED
66 67 A A S S- 0 0 58 71 93 AAAAGAAARAAGGGGAGAAGWGWRRAAAAG.GPAAPPSAPPS.S.C.....ALLLLLLLLLLLLLLLGPL
67 68 A P - 0 0 53 72 51 PPPSPPPPANNPPPPPPAPPPPPAASSSPP.QPCCATGCAAS.SPC.....PPPPPPPPPPPPPPPPSCP
68 69 A P S S+ 0 0 71 80 72 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPP.SAAAGPDAGGS.SGPSSSPSEEEEEEEEEEEEEEEEPDE
69 70 A Q + 0 0 182 81 56 QQQQQQQQQQQQQQQQQQQQQQQQQPPQQQ.QLLLGPQLGGPGPPSPPPAPRQQQQQQQQQQQQQQQGHQ
70 71 A L - 0 0 102 83 43 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLVVVVLVVVVVVVDVVVVVVVVVVVVVVVVVVVVVVDIV
71 72 A P - 0 0 97 83 12 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPAPPPPPPPPPPPPPPPPPPPPPPAPP
72 73 A E > + 0 0 116 83 14 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDDEEHDDEEEEEEEEEEDDEEEEEEEEEEEEEEEEEDE
73 74 A A T 3 S+ 0 0 55 83 56 AAAAAAAAAAAAAAAAAAAAAAAAAAAAGAAAASSSASSSSTSTPHTTTSTASASSSSSSSSSSSSSPAS
74 75 A L T 3 S+ 0 0 161 84 45 LLLLLLLLLLLLLLLLLLLLLLLLLLLQLLLLLLLLLLLLLIVIGIIIIIIVIIIIIIIIIIIIIIITII
75 76 A L S < S+ 0 0 89 84 89 LLLLLLLLLLLLLLSLLLLLLLLLLLLLLLSLTTTILNTIITITNSTTTSTCSSSSSSSSSSSSSSSSSS
76 77 A L + 0 0 101 84 83 LLLLLLLLLLLLLLLLLLLLLLLLLLLPLLLLNNNNNNNNNNNNGSNNNNNSNNNNNNNNNNNNNNNSNN
77 78 A Q S S- 0 0 143 84 63 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQIIILQVILLVLVCVVVVVVQQQQQQQQQQQQQQQQHKQ
78 79 A R S S- 0 0 113 84 40 RRRRRRRRRRRRRRRRRRRRRRRRRPPTRRRRKKKRKKKRRKRKKKKKKKKKKKKKKKKKKKKKKKKKKK
79 80 A R E -G 159 0B 84 84 2 RRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRPRRRRRRRRRRRRRRRRRRRRRRRRR
80 81 A R E +G 158 0B 135 84 90 RRRRRRRRRRRRRRRRRRRRRRRRRRRFRRRRTTTTTTTTTTTTTTTTTTTGGGGGGGGGGGGGGGGTNG
81 82 A V E -G 157 0B 2 84 0 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVV
82 83 A T - 0 0 44 84 67 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTRRRRRRRRRRRRRRRRRRRKKKKKKKKKKKKKKKKRRK
83 84 A V - 0 0 1 84 6 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVIIIVVIIVVVVVIVVVVVVVVVVVVVVVVVVVVVVIVV
84 85 A R >>> - 0 0 63 84 93 RRRRRRRRRRRRRRRRRRRRRRRRRRRHRRRRVVVLVSVLLTLTVTTTTTTLLLLLLLLLLLLLLLLVVL
85 86 A K T 345S+ 0 0 95 84 0 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
86 87 A A T 345S+ 0 0 49 84 55 AAAAAGAAAAAAAAAAAAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
87 88 A D T <45S+ 0 0 87 84 19 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDEDDDDDEEEEEEEEEEEEEEEEEEEE
88 89 A A T <5S- 0 0 34 84 75 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAVVVAAVVAAVAVAVVVVVVLLLLLLLLLLLLLLLLAVL
89 90 A G < - 0 0 21 84 7 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
90 91 A G - 0 0 35 84 0 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
91 92 A L + 0 0 44 84 0 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
92 93 A G + 0 0 17 84 0 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
93 94 A I - 0 0 32 84 4 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIVIIIVVIVIIIIIIIIIIIIIIIIIIIIIIIIIII
94 95 A S E +H 109 0B 44 84 0 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS
95 96 A I E -H 107 0B 17 84 0 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
96 97 A K E +H 106 0B 132 84 0 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
97 98 A G E - 0 0B 23 84 1 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGEGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
98 99 A G E >>> +H 103 0B 15 84 0 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGgGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
99 100 A R T 345 + 0 0 105 84 32 RRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRQKRrRKRKRKKKKKKKKKKKKKKKKKKKKKKRKK
100 101 A E T 345S+ 0 0 168 84 0 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE
101 102 A N T <45S- 0 0 132 84 0 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
102 103 A K T <5S+ 0 0 171 84 12 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKHKKKKKKKKKKKKKKKKKKKKKKHKK
103 104 A M E < -H 98 0B 107 84 0 MMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMM
104 105 A P E - 0 0B 32 84 0 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP
105 106 A I E + 0 0B 10 84 0 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
106 107 A L E -HI 96 127B 40 84 1 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
107 108 A I E +H 95 0B 9 84 0 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
108 109 A S E - 0 0B 45 84 0 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS
109 110 A K E -H 94 0B 99 84 0 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
110 111 A I - 0 0 32 84 0 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
111 112 A F > - 0 0 91 84 0 FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
112 113 A K T 3 S- 0 0 152 84 12 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKKKKKKKKKKKKKKKKKKKKKKKKK
113 114 A G T 3 S+ 0 0 41 84 1 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGSGG
114 115 A L S X> S- 0 0 56 84 1 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
115 116 A A H 3> S+ 0 0 0 84 0 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
116 117 A A H 34 S+ 0 0 3 84 0 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
117 118 A D H <4 S+ 0 0 80 84 0 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDDDDDDDDD
118 119 A Q H < S+ 0 0 84 84 13 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQQQLLQLQQQQQQQQQQQQQQQQQQQQQQQQQQQ
119 120 A T >< + 0 0 24 84 16 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTSTTTTTTTTTTTTTTTTTTTTTTSTT
120 121 A E T 3 S+ 0 0 130 84 50 EEEEEEEEEEEEEGEEEEEEGGGEEEEEEGEEEEEGEEEGGEGEREEEEEEQQQQQQQQQQQQQQQQGEQ
121 122 A A T 3 S+ 0 0 39 84 21 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAASSASALAAAAAAAAAAAAAAAAAAAAAAEAA
122 123 A L < + 0 0 8 84 0 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
123 124 A F - 0 0 85 84 16 FFFFFFFFYFFFFFFFFFFFFFFYYFFFFFFFFFFYFFFYYYYYFYYYYYYYYYYYYYYYYYYYYYYFYY
124 125 A V S S+ 0 0 84 84 1 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVV
125 126 A G S S+ 0 0 30 84 0 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
126 127 A D - 0 0 0 84 0 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
127 128 A A E -IJ 106 160B 1 84 1 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
128 129 A I E + J 0 159B 15 84 0 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
129 130 A L E + 0 0B 17 84 1 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLILLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
130 131 A S E +KJ 135 158B 11 84 7 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS
131 132 A V E - J 0 157B 6 84 0 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVV
132 133 A N S S- 0 0 67 84 0 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
133 134 A G S S+ 0 0 68 84 4 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGSGGGSGGGGGGGGGGGGGGGGGGGGGG
134 135 A E - 0 0 128 84 83 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAAVGYGVVYVYTCYYYCNAAAAAAAAAAAAAAAATAA
135 136 A D B +K 130 0B 101 84 8 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
136 137 A L > + 0 0 30 84 0 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
137 138 A S T 3 S+ 0 0 42 84 59 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSRSSSRSRRRRRRRRRRRRRRRRRRRRRRRRRRR
138 139 A S T 3 S+ 0 0 117 84 60 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSDDDETDDEEEEEDEEEEEEDDDDDDDDDDDDDDDDEDD
139 140 A A S < S- 0 0 10 84 0 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
140 141 A T >> - 0 0 44 84 5 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTSSTTTSTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
141 142 A H H >> S+ 0 0 44 84 0 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
142 143 A D H 3> S+ 0 0 114 84 0 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
143 144 A E H <> S+ 0 0 109 84 16 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDEEEDDEDEQEEEEEEEEEEEEEEEEEEEEEEQEE
144 145 A A H >>S-EF 213 238A 2 84 9 AAAASSSASSSSSSSASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS
234 235 A A T 345S- 0 0 41 83 49 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAFAAAASSSASPPPPPPPPPPPPPPPPAPP
235 236 A D T 345S+ 0 0 99 84 18 DDDDDDDDEDDDDDDDDDDDDDDEEDDDDDDDDDDDDDDDDNDTSDSTNDDDDDDDDDDDDDDDDDDDDD
236 237 A G T <45S+ 0 0 59 84 56 GGGGGGGGGGGGGDGGGGGGGGGGGGGGGDGGGGGGGGGGGRGRGRRRRRRAAAAAAATAAAAAAAAGCA
237 238 A Q T <5S- 0 0 107 84 58 QQQQQQQQQQQQQQQQQQQQQQQQQRRQQQQQRRRRRRRRRKRKKKKKKKKKKKKKKKKKKKKKKKKKKK
238 239 A D E < - F 0 233A 12 84 63 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDIIIDDHIDDNDNPKNNNQTHHHHHHHHHHHHHHHHQHH
239 240 A A E + F 0 232A 52 84 52 AAATTTTTTTTTTTTPTTTTTTTTTTTTTSTPPSSVISSVVSVSASSSSSSTTTTTTTTTTTTTTMMSTT
240 241 A V E - F 0 231A 1 83 39 VVVLLVIFLLLLLLLLLLLLLLLLLLLLL.LLLLLLLALLLVLVVVVMVAVVVVVVVVVVVVVVVVVVVV
241 242 A F E + F 0 230A 26 84 44 FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFLFFFFFFFFFFFFCFFFFFFIVIIIIIIIIIIIIIISVI
242 243 A L E -BF 14 229A 0 84 3 LLLLLLLLLLLVLLLLLLLLLLLLLLLLLLLLLLLFLLLFFLFLLLLLLLLLLLLLLLLLLLLLLLLLLL
243 244 A R E -B 13 0A 51 84 0 RRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRR
244 245 A A - 0 0 2 84 55 AAAAAAAAAAAAATAAAAAAAAAAAAAAATAAAAAAATAAAAAALAAAAAASSSSSSSSSSSSSSSSGCS
245 246 A K S S+ 0 0 173 84 18 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKPKKKKKKKKKKKKKKKKKKKKKKKKK
246 247 A D S > S- 0 0 87 84 2 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEEDDDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
247 248 A E H > S+ 0 0 76 84 68 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAEEEPEPGPPPPPHPSSSSSSTSSSSSSSSAPS
248 249 A A H > S+ 0 0 54 84 20 AAAAAAAAAAAATTAAAAAAAAAAAAAAAAAAAAAGAAAGGAGAAAAAAAAAAAAAAAAAAAAAAAAATA
249 250 A S H > S+ 0 0 49 82 69 SSSSSSSTSSSS SSSSSSGGGSSSSSSGSSSSSTSSSTTMTMTMMMMMMTTTTTTTTATTTTTTTTMT
250 251 A A H X S+ 0 0 4 82 5 AAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAVAA
251 252 A R H X S+ 0 0 190 82 58 RRRRRRRRRRRR RRRRKRRRRRRKKKRRRRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
252 253 A S H X S+ 0 0 73 82 44 SSSSSSSSSSSS SSSSSSSSSSSSSSSSSSASSSASSSSSSSSSSSSSAAAAAAAAAAAAAAAAASAA
253 254 A W H >X S+ 0 0 24 82 0 WWWWWWWWWWWW WWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWW
254 255 A A H 3X S+ 0 0 4 82 76 AAAAAAAAGAAA AAAAAAAAAGAAAAAAAAFFFFLFFFFYFYFYYYYYYFFFFFFFFFFFFFFFFYFF
255 256 A G H 3X S+ 0 0 34 82 62 GGGGTGGGSGGT TGTAATSSSSSAAAASTGNNNNASNNNNNNGNNNNNNSSSSSSSSSSSSSSSSANS
256 257 A A H S+ 0 0 72 32 23 S G
18 19 A A T 3 + 0 0 24 32 54 G T
19 20 A G T 3 S- 0 0 73 32 57 G L
20 21 A S S < S+ 0 0 129 32 55 G E
21 22 A G - 0 0 63 32 24 G T
22 23 A A + 0 0 88 32 56 A R
23 24 A G S S+ 0 0 82 32 39 A V
24 25 A G S S- 0 0 53 34 44 QGR
25 26 A E - 0 0 113 38 46 NQG
26 27 A R - 0 0 167 58 30 R GVA
27 28 A W E +A 15 0A 75 78 5 W WWWWWW WTWW
28 29 A Q E -A 14 0A 69 78 80 M HHHYHH VLHY
29 30 A R E +A 13 0A 163 79 33 R KKAKKKRRPKR
30 31 A V E -A 12 0A 21 80 9 VVVVVVVVVVSVV
31 32 A L E -AC 11 42A 47 80 19 LALLLLLLAVSYL
32 33 A L E -AC 10 41A 1 80 59 AAAAAVVVAAAAV
33 34 A S E -AC 9 40A 19 80 72 TENNSNNNEESST
34 35 A L E +AC 8 39A 7 80 3 LLLLLLLLLLLLL
35 36 A A - 0 0 45 80 66 TTSGGNNNTSQKE
36 37 A E S S+ 0 0 99 80 29 ERDGDEEERGGGT
37 38 A D S S+ 0 0 73 80 21 DEEEEDEEEEMED
38 39 A A E - D 0 209A 28 80 69 TTSASAAATSVDF
39 40 A L E -CD 34 208A 0 80 7 LLLLLLLLLLVLL
40 41 A T E -CD 33 207A 47 80 62 TTTVTITTTSQIA
41 42 A V E +CD 32 206A 7 80 38 VLLLLLLLLLDII
42 43 A S E -C 31 0A 45 80 37 NTSSSSSSTTTSS
43 44 A P - 0 0 80 80 59 PACGCSCCAGEIL
44 45 A A - 0 0 36 80 61 GEEEEEEEEDLAD
45 46 A D - 0 0 130 81 42 EAEEDEEEAADDE
46 47 A G + 0 0 67 81 43 aevrpgeEdagds
47 48 A E S S- 0 0 156 76 74 kpdadtnDadngh
48 49 A P + 0 0 130 80 65 ANPEPGNCNSGSS
49 50 A G + 0 0 65 82 49 AGTGTGAGGLTNG
50 51 A P S S- 0 0 129 82 59 PNTGNGNPNPGSH
51 52 A E - 0 0 133 82 70 TENGSASDDGNTN
52 53 A P S S+ 0 0 123 82 47 ppSGpsnrpsgrg
53 54 A E S S+ 0 0 155 73 70 dn..agaasgdnd
54 55 A P - 0 0 87 80 40 PPPGRSRRPPATN
55 56 A A - 0 0 75 82 68 PAKSTPTTGPVNG
56 57 A Q - 0 0 117 82 77 NRGAPQAARSGTG
57 58 A L - 0 0 171 84 65 LVVVFVFFSPLLG
58 59 A N S S+ 0 0 102 84 69 SPRRSGTTGPDDS
59 60 A G + 0 0 40 83 39 SpTTDVDDAAMGg
60 61 A A S S+ 0 0 83 52 94 .g...R......g
61 62 A A - 0 0 33 55 65 .P...T......G
62 63 A E S S+ 0 0 192 60 70 .EAA.A......D
63 64 A P S S+ 0 0 103 61 108 .QFF.F......H
64 65 A G S S- 0 0 78 68 69 .LTT.T...P..L
65 66 A A S S+ 0 0 51 69 76 .QDD.D...P..L
66 67 A A S S- 0 0 58 71 93 .SLP.LLL.R..N
67 68 A P - 0 0 53 72 51 .QPP.PPP.G..N
68 69 A P S S+ 0 0 71 80 72 SNEESDEE.PC.N
69 70 A Q + 0 0 182 81 56 PQQQQQRR.AD.T
70 71 A L - 0 0 102 83 43 VGVVVVVVSGV.M
71 72 A P - 0 0 97 83 12 PPPPPPPPREP.D
72 73 A E > + 0 0 116 83 14 EDEEEEEEEAD.N
73 74 A A T 3 S+ 0 0 55 83 56 TGAAASAAGSH.g
74 75 A L T 3 S+ 0 0 161 84 45 ISIVIIIISAVLv
75 76 A L S < S+ 0 0 89 84 89 TSASAAAASSATA
76 77 A L + 0 0 101 84 83 NENNNNNNEPNGN
77 78 A Q S S- 0 0 143 84 63 VAKKRQRRAPQQQ
78 79 A R S S- 0 0 113 84 40 KVKKKKKKVVKKK
79 80 A R E -G 159 0B 84 84 2 RRRRRRRRRRRRR
80 81 A R E +G 158 0B 135 84 90 TKCCCGCCKRHVH
81 82 A V E -G 157 0B 2 84 0 VVVVVVVVVVVVV
82 83 A T - 0 0 44 84 67 RRKKKKKKRRRRR
83 84 A V - 0 0 1 84 6 VVVVVVVVVVIVI
84 85 A R >>> - 0 0 63 84 93 TVVLILTTVVIFI
85 86 A K T 345S+ 0 0 95 84 0 KKKKKKKKKKKKK
86 87 A A T 345S+ 0 0 49 84 55 QQQQQQQQQQSES
87 88 A D T <45S+ 0 0 87 84 19 DEDEEEEEEEDDD
88 89 A A T <5S- 0 0 34 84 75 VSTLVLIISANNN
89 90 A G < - 0 0 21 84 7 GGGGGGGGGGNSN
90 91 A G - 0 0 35 84 0 GGGGGGGGGGGGG
91 92 A L + 0 0 44 84 0 LLLLLLLLLLLLL
92 93 A G + 0 0 17 84 0 GGGGGGGGGGGGG
93 94 A I - 0 0 32 84 4 IIIIIIVVIIIII
94 95 A S E +H 109 0B 44 84 0 SSSSSSSSSSSSS
95 96 A I E -H 107 0B 17 84 0 IIIIIIIIIIIII
96 97 A K E +H 106 0B 132 84 0 KKKKKKKKKKKKK
97 98 A G E - 0 0B 23 84 1 GGGGGGGGGGGGG
98 99 A G E >>> +H 103 0B 15 84 0 GGGGGGGGGGGGG
99 100 A R T 345 + 0 0 105 84 32 KRKKKKKKRRRSR
100 101 A E T 345S+ 0 0 168 84 0 EEEEEEEEEEEEE
101 102 A N T <45S- 0 0 132 84 0 NNNNNNNNNNNNN
102 103 A K T <5S+ 0 0 171 84 12 KRKKKKKKRRRKR
103 104 A M E < -H 98 0B 107 84 0 MMMMMMMMMMMMM
104 105 A P E - 0 0B 32 84 0 PPPPPPPPPPPPP
105 106 A I E + 0 0B 10 84 0 IIIIIIIIIIIII
106 107 A L E -HI 96 127B 40 84 1 LLLLLLLLLLLIL
107 108 A I E +H 95 0B 9 84 0 IIIIIIIIIIIII
108 109 A S E - 0 0B 45 84 0 SSSSSSSSSSSSS
109 110 A K E -H 94 0B 99 84 0 KKKKKKKKKKKKK
110 111 A I - 0 0 32 84 0 IIIIIIIIIIIII
111 112 A F > - 0 0 91 84 0 FFFFFFFFFFFFF
112 113 A K T 3 S- 0 0 152 84 12 KPKKKKKKPPRKR
113 114 A G T 3 S+ 0 0 41 84 1 GGGGGGGGGGGGG
114 115 A L S X> S- 0 0 56 84 1 LLLLLLLLLLMMM
115 116 A A H 3> S+ 0 0 0 84 0 AAAAAAAAAAAAA
116 117 A A H 34 S+ 0 0 3 84 0 AAAAAAAAAAAAA
117 118 A D H <4 S+ 0 0 80 84 0 DDDDDDDDDDDDD
118 119 A Q H < S+ 0 0 84 84 13 QQQQQQQQQQQRQ
119 120 A T >< + 0 0 24 84 16 TSTTTTTTSSATA
120 121 A E T 3 S+ 0 0 130 84 50 ERQQQQQQRRKEK
121 122 A A T 3 S+ 0 0 39 84 21 AASAAAAAAAGKG
122 123 A L < + 0 0 8 84 0 LLLLLLLLLLLLL
123 124 A F - 0 0 85 84 16 YRYYYYYYRRYYY
124 125 A V S S+ 0 0 84 84 1 VVVVVVVVVLVVV
125 126 A G S S+ 0 0 30 84 0 GGGGGGGGGGGGG
126 127 A D - 0 0 0 84 0 DDDDDDDDDDDDD
127 128 A A E -IJ 106 160B 1 84 1 AAAAAAAAAAAAA
128 129 A I E + J 0 159B 15 84 0 IIIIIIIIIIIVI
129 130 A L E + 0 0B 17 84 1 LLLLLLLLLLLLL
130 131 A S E +KJ 135 158B 11 84 7 SSSASSSSSSTAS
131 132 A V E - J 0 157B 6 84 0 VVVVVVVVVVVVV
132 133 A N S S- 0 0 67 84 0 NNNNNNNNNNNNN
133 134 A G S S+ 0 0 68 84 4 SGGGGGGGGGGGG
134 135 A E - 0 0 128 84 83 YSVTIAVVSTEEE
135 136 A D B +K 130 0B 101 84 8 DDNDNDNNDDEDE
136 137 A L > + 0 0 30 84 0 LLLLLLLLLLLLL
137 138 A S T 3 S+ 0 0 42 84 59 RRRRRRRRRRRRR
138 139 A S T 3 S+ 0 0 117 84 60 EEDDDDDDEQDEE
139 140 A A S < S- 0 0 10 84 0 AAAAAAAAAAAAA
140 141 A T >> - 0 0 44 84 5 TTTTTTTTTTTTT
141 142 A H H >> S+ 0 0 44 84 0 HHHHHHHHHHHHH
142 143 A D H 3> S+ 0 0 114 84 0 DDDDDDDDDDDDD
143 144 A E H <> S+ 0 0 109 84 16 ELEEEEEELQEQE
144 145 A A H >>S-EF 213 238A 2 84 9 SSSSSSSSSSSSS
234 235 A A T 345S- 0 0 41 83 49 SPPPSPPPPPP.P
235 236 A D T 345S+ 0 0 99 84 18 TDDDDDDDDDDPD
236 237 A G T <45S+ 0 0 59 84 56 RGAAAAAAGSGDG
237 238 A Q T <5S- 0 0 107 84 58 KQKKKKRRQRVLV
238 239 A D E < - F 0 233A 12 84 63 NHHHNHHHHNHKH
239 240 A A E + F 0 232A 52 84 52 STTTTTTTTTSSS
240 241 A V E - F 0 231A 1 83 39 MVVVIVVVVLCLC
241 242 A F E + F 0 230A 26 84 44 FVVVVIVVVIIII
242 243 A L E -BF 14 229A 0 84 3 LLLLMLLLLLLML
243 244 A R E -B 13 0A 51 84 0 RRRRRRRRRRRRR
244 245 A A - 0 0 2 84 55 ACSSHSCCCCAFA
245 246 A K S S+ 0 0 173 84 18 KKKKTKPPKKATT
246 247 A D S > S- 0 0 87 84 2 DDDDDDDDDDDDD
247 248 A E H > S+ 0 0 76 84 68 PGSSSSQQATSES
248 249 A A H > S+ 0 0 54 84 20 AAAASAPPPAARA
249 250 A S H > S+ 0 0 49 82 69 MTTTSTSSTTETE
250 251 A A H X S+ 0 0 4 82 5 AAVAAAAAAAAAA
251 252 A R H X S+ 0 0 190 82 58 QNQQQQLLNHLSL
252 253 A S H X S+ 0 0 73 82 44 SSAATASSSSVSI
253 254 A W H >X S+ 0 0 24 82 0 WWWWWWWWWWWWW
254 255 A A H 3X S+ 0 0 4 82 76 YFFFFFFFFFFFF
255 256 A G H 3X S+ 0 0 34 82 62 NTNNTNSSTVNSN
256 257 A A H