Complet list of 1wz5 hssp file
Complete list of 1wz5.hssp file
HSSP HOMOLOGY DERIVED SECONDARY STRUCTURE OF PROTEINS , VERSION 2.0 2011
PDBID 1WZ5
THRESHOLD according to: t(L)=(290.15 * L ** -0.562) + 5
REFERENCE Sander C., Schneider R. : Database of homology-derived protein structures. Proteins, 9:56-68 (1991).
CONTACT Maintained at http://www.cmbi.ru.nl/ by Maarten L. Hekkelman
DATE file generated on 2014-05-12
HEADER TOXIN 24-FEB-05 1WZ5
COMPND MOL_ID: 1; MOLECULE: POTASSIUM CHANNEL BLOCKING TOXIN 1; CHAIN: A; SYN
SOURCE MOL_ID: 1; ORGANISM_SCIENTIFIC: PANDINUS IMPERATOR; ORGANISM_COMMON: E
AUTHOR G.FERRAT
DBREF 1WZ5 A 1 35 UNP Q10726 SCKG_PANIM 1 35
SEQLENGTH 35
NCHAIN 1 chain(s) in 1WZ5 data set
NALIGN 29
NOTATION : ID: EMBL/SWISSPROT identifier of the aligned (homologous) protein
NOTATION : STRID: if the 3-D structure of the aligned protein is known, then STRID is the Protein Data Bank identifier as taken
NOTATION : from the database reference or DR-line of the EMBL/SWISSPROT entry
NOTATION : %IDE: percentage of residue identity of the alignment
NOTATION : %SIM (%WSIM): (weighted) similarity of the alignment
NOTATION : IFIR/ILAS: first and last residue of the alignment in the test sequence
NOTATION : JFIR/JLAS: first and last residue of the alignment in the alignend protein
NOTATION : LALI: length of the alignment excluding insertions and deletions
NOTATION : NGAP: number of insertions and deletions in the alignment
NOTATION : LGAP: total length of all insertions and deletions
NOTATION : LSEQ2: length of the entire sequence of the aligned protein
NOTATION : ACCNUM: SwissProt accession number
NOTATION : PROTEIN: one-line description of aligned protein
NOTATION : SeqNo,PDBNo,AA,STRUCTURE,BP1,BP2,ACC: sequential and PDB residue numbers, amino acid (lower case = Cys), secondary
NOTATION : structure, bridge partners, solvent exposure as in DSSP (Kabsch and Sander, Biopolymers 22, 2577-2637(1983)
NOTATION : VAR: sequence variability on a scale of 0-100 as derived from the NALIGN alignments
NOTATION : pair of lower case characters (AvaK) in the alignend sequence bracket a point of insertion in this sequence
NOTATION : dots (....) in the alignend sequence indicate points of deletion in this sequence
NOTATION : SEQUENCE PROFILE: relative frequency of an amino acid type at each position. Asx and Glx are in their
NOTATION : acid/amide form in proportion to their database frequencies
NOTATION : NOCC: number of aligned sequences spanning this position (including the test sequence)
NOTATION : NDEL: number of sequences with a deletion in the test protein at this position
NOTATION : NINS: number of sequences with an insertion in the test protein at this position
NOTATION : ENTROPY: entropy measure of sequence variability at this position
NOTATION : RELENT: relative entropy, i.e. entropy normalized to the range 0-100
NOTATION : WEIGHT: conservation weight
## PROTEINS : identifier and alignment statistics
NR. ID STRID %IDE %WSIM IFIR ILAS JFIR JLAS LALI NGAP LGAP LSEQ2 ACCNUM PROTEIN
1 : KAX61_PANIM 1WZ5 0.97 0.97 1 34 1 34 34 0 0 35 Q10726 Potassium channel toxin alpha-KTx 6.1 OS=Pandinus imperator PE=1 SV=1
2 : KAX62_SCOMA 1WPD 0.64 0.79 2 34 1 33 33 0 0 34 P80719 Potassium channel toxin alpha-KTx 6.2 OS=Scorpio maurus palmatus PE=1 SV=1
3 : KAX64_PANIM 1N8M 0.64 0.85 2 34 4 36 33 0 0 38 P58498 Potassium channel toxin alpha-KTx 6.4 OS=Pandinus imperator PE=1 SV=1
4 : KAX6D_HETSP 1V56 0.61 0.79 2 34 1 33 33 0 0 34 P84094 Potassium channel toxin alpha-KTx 6.13 OS=Heterometrus spinifer PE=1 SV=1
5 : KAX65_PANIM 1QKY 0.58 0.73 2 34 4 36 33 0 0 38 P58490 Potassium channel toxin alpha-KTx 6.5 OS=Pandinus imperator PE=1 SV=1
6 : KAX6F_HEMLE 0.58 0.76 2 34 1 33 33 0 0 35 P85528 Potassium channel toxin alpha-KTx 6.15 OS=Hemiscorpius lepturus PE=1 SV=1
7 : KAX6A_OPICA 0.56 0.82 1 34 25 58 34 0 0 60 Q6XLL5 Potassium channel toxin alpha-KTx 6.10 OS=Opistophthalmus carinatus PE=2 SV=1
8 : H2CYS1_PANCV 0.53 0.72 3 34 30 61 32 0 0 63 H2CYS1 Alpha-KTx-like peptide OS=Pandinus cavimanus PE=3 SV=1
9 : I6NXS5_HETLA 0.53 0.77 3 32 2 31 30 0 0 35 I6NXS5 Kv1.3 potassium channel blocker (Fragment) OS=Heterometrus laoticus GN=Tx2 PE=2 SV=1
10 : KAX63_HETSP 1WPD 0.53 0.73 3 32 2 31 30 0 0 34 P59867 Potassium channel toxin alpha-KTx 6.3 OS=Heterometrus spinifer PE=1 SV=1
11 : KAX66_OPICA 0.53 0.81 1 32 26 57 32 0 0 61 Q6XLL9 Potassium channel toxin alpha-KTx 6.6 OS=Opistophthalmus carinatus PE=2 SV=1
12 : KAX67_OPICA 0.53 0.81 1 32 26 57 32 0 0 61 Q6XLL8 Potassium channel toxin alpha-KTx 6.7 OS=Opistophthalmus carinatus PE=2 SV=1
13 : KAX69_OPICA 0.53 0.76 1 34 26 59 34 0 0 61 Q6XLL6 Potassium channel toxin alpha-KTx 6.9 OS=Opistophthalmus carinatus PE=2 SV=1
14 : I6NWV2_HETLA 0.52 0.79 2 34 27 59 33 0 0 61 I6NWV2 Kv1.3 potassium channel blocker (Precursor) OS=Heterometrus laoticus GN=Tx3 PE=3 SV=1
15 : KAX24_CENNO 0.52 0.71 3 33 6 36 31 0 0 38 Q9TXD1 Potassium channel toxin alpha-KTx 2.4 OS=Centruroides noxius PE=1 SV=1
16 : KAX6H_OPICY 0.52 0.85 2 34 1 33 33 0 0 34 P86116 Potassium channel toxin alpha-KTx 6.17 OS=Opisthacanthus cayaporum PE=1 SV=2
17 : KAX1A_PARTR 0.50 0.78 2 33 4 35 32 0 0 37 P83112 Potassium channel toxin alpha-KTx 1.10 OS=Parabuthus transvaalicus PE=1 SV=1
18 : KAX68_OPICA 0.50 0.81 1 32 26 57 32 0 0 61 Q6XLL7 Potassium channel toxin alpha-KTx 6.8 OS=Opistophthalmus carinatus PE=2 SV=1
19 : A0RZD1_MESMA 0.48 0.70 2 34 25 57 33 0 0 57 A0RZD1 Potassium-channel toxin protein OS=Mesobuthus martensii GN=TX1 PE=3 SV=1
20 : B8XH28_BUTOS 0.48 0.61 2 32 28 57 31 1 1 59 B8XH28 Putative potassium channel toxin Tx1 (Precursor) OS=Buthus occitanus israelis PE=3 SV=1
21 : B8XH29_BUTOS 0.48 0.61 2 32 28 57 31 1 1 60 B8XH29 Putative potassium channel toxin Tx260 OS=Buthus occitanus israelis PE=3 SV=1
22 : B8XH44_BUTOS 0.48 0.58 2 34 29 61 33 0 0 73 B8XH44 Putative potassium channel toxin Tx771 OS=Buthus occitanus israelis PE=3 SV=1
23 : KAX15_MESMA 1BIG 0.48 0.70 2 34 25 57 33 0 0 57 Q9NII6 Potassium channel toxin alpha-KTx 1.5 OS=Mesobuthus martensii PE=1 SV=1
24 : KAX23_CENLL 0.48 0.70 2 33 5 37 33 1 1 38 P45629 Potassium channel toxin alpha-KTx 2.3 OS=Centruroides limpidus limpidus PE=1 SV=1
25 : KAX2A_CENEL 0.48 0.67 2 33 5 37 33 1 1 38 P0C163 Potassium channel toxin alpha-KTx 2.10 OS=Centruroides elegans PE=1 SV=1
26 : KAX3A_BUTOS 0.48 0.61 2 32 28 57 31 1 1 59 P0C908 Potassium channel toxin alpha-KTx 3.10 OS=Buthus occitanus israelis PE=1 SV=1
27 : KAX46_TITST 0.48 0.71 3 33 6 36 31 0 0 37 P0CB56 Potassium channel toxin alpha-KTx 4.6 OS=Tityus stigmurus PE=1 SV=1
28 : KAX6B_OPIMA 1WMT 0.48 0.73 2 34 26 58 33 0 0 63 P0C194 Potassium channel toxin alpha-KTx 6.11 OS=Opisthacanthus madagascariensis PE=1 SV=1
29 : KAX44_TITOB 0.47 0.69 2 33 5 36 32 0 0 37 P60210 Potassium channel toxin alpha-KTx 4.4 OS=Tityus obscurus PE=1 SV=1
## ALIGNMENTS 1 - 29
SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
1 1 A L 0 0 173 7 32 L V VVI V
2 2 A V + 0 0 120 25 19 VVIIIII IIII IMIVVVVVVVV IV
3 3 A K S S- 0 0 161 30 45 KSRRRKRRSSKKRSKRRKKKKSKKKKKPK
4 4 A a + 0 0 48 30 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCC
5 5 A R > + 0 0 180 30 73 RTGSTTSGRRRRSTFQKRTRRRTTSRRRR
6 6 A G T 4 + 0 0 25 30 54 GGGGGLGGTTTTGGAGSTGGGYGSLGGGG
7 7 A T T 4 S- 0 0 127 30 51 TSSSTSSSPPPPTSTSSPSSSGSPPSSTS
8 8 A S T > S+ 0 0 79 30 57 SKRRKKKSKKKKRKSNKKKRRSKQQRPSK
9 9 A D T >< S+ 0 0 99 30 29 DDDDDDQEDDDDEQQQEDQDDDQQQDEDE
10 10 A b T 3> S+ 0 0 22 30 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCC
11 11 A G H 3> S+ 0 0 16 30 83 GYYYYYYRAAAAYYWYLAWLLAWLLLLYL
12 12 A R H S+ 0 0 98 30 33 PPPPPPPPPPPPPPPHKPVPPPVPPPKPA
14 14 A c H >X S+ 0 0 21 30 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCC
15 15 A Q H 3< S+ 0 0 96 30 48 QRQMRKKARRRRQKKRKRKKKKKKKKKEK
16 16 A Q H 3< S+ 0 0 158 30 57 QKKKYKQRKKKKKRKEQKQKKRQDDKQKA
17 17 A Q H << S+ 0 0 165 30 79 QQRQIEQAEEQQLKAKAQMAALMRRAAKA
18 18 A T S < S- 0 0 39 30 67 TTTTTTTTTTTTTTITTTFGGKFFFGIYV
19 19 A G - 0 0 33 30 35 GGGGGGGGGGGGGGGGGGGMMCGggMGNG
20 20 A X S S+ 0 0 126 26 77 CCCCCCCYCCCCCCSCRCK..LKhh.KCK
21 21 A P S S+ 0 0 103 30 75 PPPPFPTYPPPPLPLMPPPRRLPAARAAA
22 22 A N + 0 0 4 30 80 NNNNNRNSHYHHNNQNNHNFFPNGGFARA
23 23 A S + 0 0 79 30 40 SAAASASSGGGGAASGGAGGGSGGGGGAG
24 24 A K E -A 31 0A 86 30 3 KKKKRKKKKKKKKKKKKKKKKKKKKKKKK
25 25 A a E +A 30 0A 45 30 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCC
26 26 A I E > -A 29 0A 69 30 32 IIIIIIMIMMMMMMMIMMMIIIMIIIMMM
27 27 A N T 3 S+ 0 0 146 30 0 NNNNNNNNNNNNNNNNNNNNNNNNNNNNN
28 28 A R T 3 S- 0 0 208 30 72 RKKKKRKGRRRRKKGRRKGSSGGGGSGRG
29 29 A M E < -A 26 0A 110 30 71 MSTSSNVSKKTTASKVKTKKKKKKKKKHK
30 30 A b E +A 25 0A 37 30 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCC
31 31 A K E -A 24 0A 77 30 46 KKKKKKKVKKRRKKKKKRRHHTRKKHKNK
32 32 A c + 0 0 31 30 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCC
33 33 A Y S S+ 0 0 150 22 0 YYYYYYYY YYYYY Y YYYY YYY
34 34 A G 0 0 44 16 38 GGGGGGGG GG G S PS N
35 35 A X 0 0 186 0 0
## SEQUENCE PROFILE AND ENTROPY
SeqNo PDBNo V L I M F W Y G A P S T C H R K Q E N D NOCC NDEL NINS ENTROPY RELENT WEIGHT
1 1 A 57 29 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0.956 31 0.67
2 2 A 48 0 48 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0.833 27 0.81
3 3 A 0 0 0 0 0 0 0 0 0 3 17 0 0 0 27 53 0 0 0 0 30 0 0 1.100 36 0.54
4 4 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 30 0 0 0.000 0 1.00
5 5 A 0 0 0 0 3 0 0 7 0 0 13 23 0 0 47 3 3 0 0 0 30 0 0 1.485 49 0.26
6 6 A 0 7 0 0 0 0 3 63 3 0 7 17 0 0 0 0 0 0 0 0 30 0 0 1.176 39 0.46
7 7 A 0 0 0 0 0 0 0 3 0 23 53 20 0 0 0 0 0 0 0 0 30 0 0 1.110 37 0.49
8 8 A 0 0 0 0 0 0 0 0 0 3 20 0 0 0 20 47 7 0 3 0 30 0 0 1.407 46 0.43
9 9 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 27 17 0 57 30 0 0 0.973 32 0.70
10 10 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 30 0 0 0.000 0 1.00
11 11 A 0 27 0 0 0 10 33 7 20 0 0 0 0 0 3 0 0 0 0 0 30 0 0 1.565 52 0.17
12 12 A 3 0 3 0 0 0 0 10 7 13 7 3 0 0 17 3 0 7 0 27 30 0 0 2.145 71 0.21
13 13 A 7 0 0 0 0 0 0 0 3 80 0 0 0 3 0 7 0 0 0 0 30 0 0 0.766 25 0.66
14 14 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 30 0 0 0.000 0 1.00
15 15 A 0 0 0 3 0 0 0 0 3 0 0 0 0 0 27 50 13 3 0 0 30 0 0 1.308 43 0.52
16 16 A 0 0 0 0 0 0 3 0 3 0 0 0 0 0 10 50 23 3 0 7 30 0 0 1.437 47 0.43
17 17 A 0 7 3 7 0 0 0 0 27 0 0 0 0 0 10 10 27 10 0 0 30 0 0 1.870 62 0.20
18 18 A 3 0 7 0 13 0 3 10 0 0 0 60 0 0 0 3 0 0 0 0 30 0 0 1.326 44 0.32
19 19 A 0 0 0 10 0 0 0 83 0 0 0 0 3 0 0 0 0 0 3 0 30 3 2 0.609 20 0.64
20 20 A 0 4 0 0 0 0 4 0 0 0 4 0 62 8 4 15 0 0 0 0 26 0 0 1.285 42 0.23
21 21 A 0 10 0 3 3 0 3 0 17 50 0 3 0 0 10 0 0 0 0 0 30 0 0 1.559 52 0.25
22 22 A 0 0 0 0 10 0 3 7 7 3 3 0 0 13 7 0 3 0 43 0 30 0 0 1.856 61 0.20
23 23 A 0 0 0 0 0 0 0 50 27 0 23 0 0 0 0 0 0 0 0 0 30 0 0 1.039 34 0.59
24 24 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 97 0 0 0 0 30 0 0 0.146 4 0.97
25 25 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 30 0 0 0.000 0 1.00
26 26 A 0 0 50 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 30 0 0 0.693 23 0.67
27 27 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 30 0 0 0.000 0 1.00
28 28 A 0 0 0 0 0 0 0 30 0 0 10 0 0 0 33 27 0 0 0 0 30 0 0 1.310 43 0.27
29 29 A 7 0 0 7 0 0 0 0 3 0 17 13 0 3 0 47 0 0 3 0 30 0 0 1.624 54 0.28
30 30 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 30 0 0 0.000 0 1.00
31 31 A 3 0 0 0 0 0 0 0 0 0 0 3 0 10 17 63 0 0 3 0 30 0 0 1.158 38 0.53
32 32 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 30 0 0 0.000 0 1.00
33 33 A 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 22 0 0 0.000 0 1.00
34 34 A 0 0 0 0 0 0 0 75 0 6 13 0 0 0 0 0 0 0 6 0 16 0 0 0.822 27 0.62
35 35 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.000 0 1.00
## INSERTION LIST
AliNo IPOS JPOS Len Sequence
24 19 23 1 gQh
25 19 23 1 gQh
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