Complet list of 1wso hssp file
Complete list of 1wso.hssp file
HSSP HOMOLOGY DERIVED SECONDARY STRUCTURE OF PROTEINS , VERSION 2.0 2011
PDBID 1WSO
THRESHOLD according to: t(L)=(290.15 * L ** -0.562) + 5
REFERENCE Sander C., Schneider R. : Database of homology-derived protein structures. Proteins, 9:56-68 (1991).
CONTACT Maintained at http://www.cmbi.ru.nl/ by Maarten L. Hekkelman
DATE file generated on 2014-05-12
HEADER NEUROPEPTIDE 08-NOV-04 1WSO
COMPND MOL_ID: 1; MOLECULE: OREXIN-A; CHAIN: A; SYNONYM: HYPOCRETIN-1; ENGINE
SOURCE MOL_ID: 1; SYNTHETIC: YES; OTHER_DETAILS: THIS SEQUENCE OCCURS NATURAL
AUTHOR T.IKEGAMI,T.TAKAI
DBREF 1WSO A 1 33 UNP O43612 OREX_HUMAN 35 66
SEQLENGTH 33
NCHAIN 1 chain(s) in 1WSO data set
NALIGN 44
NOTATION : ID: EMBL/SWISSPROT identifier of the aligned (homologous) protein
NOTATION : STRID: if the 3-D structure of the aligned protein is known, then STRID is the Protein Data Bank identifier as taken
NOTATION : from the database reference or DR-line of the EMBL/SWISSPROT entry
NOTATION : %IDE: percentage of residue identity of the alignment
NOTATION : %SIM (%WSIM): (weighted) similarity of the alignment
NOTATION : IFIR/ILAS: first and last residue of the alignment in the test sequence
NOTATION : JFIR/JLAS: first and last residue of the alignment in the alignend protein
NOTATION : LALI: length of the alignment excluding insertions and deletions
NOTATION : NGAP: number of insertions and deletions in the alignment
NOTATION : LGAP: total length of all insertions and deletions
NOTATION : LSEQ2: length of the entire sequence of the aligned protein
NOTATION : ACCNUM: SwissProt accession number
NOTATION : PROTEIN: one-line description of aligned protein
NOTATION : SeqNo,PDBNo,AA,STRUCTURE,BP1,BP2,ACC: sequential and PDB residue numbers, amino acid (lower case = Cys), secondary
NOTATION : structure, bridge partners, solvent exposure as in DSSP (Kabsch and Sander, Biopolymers 22, 2577-2637(1983)
NOTATION : VAR: sequence variability on a scale of 0-100 as derived from the NALIGN alignments
NOTATION : pair of lower case characters (AvaK) in the alignend sequence bracket a point of insertion in this sequence
NOTATION : dots (....) in the alignend sequence indicate points of deletion in this sequence
NOTATION : SEQUENCE PROFILE: relative frequency of an amino acid type at each position. Asx and Glx are in their
NOTATION : acid/amide form in proportion to their database frequencies
NOTATION : NOCC: number of aligned sequences spanning this position (including the test sequence)
NOTATION : NDEL: number of sequences with a deletion in the test protein at this position
NOTATION : NINS: number of sequences with an insertion in the test protein at this position
NOTATION : ENTROPY: entropy measure of sequence variability at this position
NOTATION : RELENT: relative entropy, i.e. entropy normalized to the range 0-100
NOTATION : WEIGHT: conservation weight
## PROTEINS : identifier and alignment statistics
NR. ID STRID %IDE %WSIM IFIR ILAS JFIR JLAS LALI NGAP LGAP LSEQ2 ACCNUM PROTEIN
1 : A2A5D9_MOUSE 1.00 1.00 2 33 34 65 32 0 0 106 A2A5D9 Orexin OS=Mus musculus GN=Hcrt PE=4 SV=1
2 : F1MRP1_BOVIN 1.00 1.00 2 33 35 66 32 0 0 131 F1MRP1 Orexin-A OS=Bos taurus GN=HCRT PE=4 SV=1
3 : F6TU74_HORSE 1.00 1.00 2 33 31 62 32 0 0 127 F6TU74 Uncharacterized protein (Fragment) OS=Equus caballus GN=HCRT PE=4 SV=1
4 : F7GWM3_MACMU 1.00 1.00 2 33 35 66 32 0 0 131 F7GWM3 Uncharacterized protein OS=Macaca mulatta GN=HCRT PE=4 SV=1
5 : G1PQX1_MYOLU 1.00 1.00 2 33 34 65 32 0 0 129 G1PQX1 Uncharacterized protein OS=Myotis lucifugus GN=HCRT PE=4 SV=1
6 : G1RKY1_NOMLE 1.00 1.00 2 33 35 66 32 0 0 131 G1RKY1 Uncharacterized protein OS=Nomascus leucogenys GN=HCRT PE=4 SV=1
7 : G1T565_RABIT 1.00 1.00 2 33 34 65 32 0 0 127 G1T565 Uncharacterized protein OS=Oryctolagus cuniculus GN=HCRT PE=4 SV=1
8 : G3HLW6_CRIGR 1.00 1.00 2 33 354 385 32 0 0 1401 G3HLW6 Potassium voltage-gated channel subfamily H member 4 OS=Cricetulus griseus GN=I79_011710 PE=4 SV=1
9 : G3RHR6_GORGO 1.00 1.00 2 33 25 56 32 0 0 121 G3RHR6 Uncharacterized protein OS=Gorilla gorilla gorilla GN=101128580 PE=4 SV=1
10 : G3SG65_GORGO 1.00 1.00 2 33 35 66 32 0 0 131 G3SG65 Uncharacterized protein OS=Gorilla gorilla gorilla GN=101128580 PE=4 SV=1
11 : G3UCF1_LOXAF 1.00 1.00 2 33 22 53 32 0 0 118 G3UCF1 Uncharacterized protein OS=Loxodonta africana GN=HCRT PE=4 SV=1
12 : G7NIK7_MACMU 1.00 1.00 2 33 35 66 32 0 0 131 G7NIK7 Hypocretin OS=Macaca mulatta GN=EGK_08729 PE=4 SV=1
13 : H0VWD3_CAVPO 1.00 1.00 2 33 31 62 32 0 0 125 H0VWD3 Uncharacterized protein (Fragment) OS=Cavia porcellus GN=HCRT PE=4 SV=1
14 : H0WKQ5_OTOGA 1.00 1.00 2 33 27 58 32 0 0 123 H0WKQ5 Uncharacterized protein (Fragment) OS=Otolemur garnettii GN=HCRT PE=4 SV=1
15 : H2NU12_PONAB 1.00 1.00 2 33 35 66 32 0 0 131 H2NU12 Uncharacterized protein OS=Pongo abelii GN=HCRT PE=4 SV=1
16 : H2QD16_PANTR 1.00 1.00 2 33 34 65 32 0 0 130 H2QD16 Uncharacterized protein OS=Pan troglodytes GN=HCRT PE=4 SV=1
17 : I3M8B0_SPETR 1.00 1.00 2 33 34 65 32 0 0 130 I3M8B0 Uncharacterized protein OS=Spermophilus tridecemlineatus GN=HCRT PE=4 SV=1
18 : L8IBS2_9CETA 1.00 1.00 2 33 28 59 32 0 0 124 L8IBS2 Orexin (Fragment) OS=Bos mutus GN=M91_17145 PE=4 SV=1
19 : L9JXM3_TUPCH 1.00 1.00 2 33 79 110 32 0 0 175 L9JXM3 Orexin OS=Tupaia chinensis GN=TREES_T100004392 PE=4 SV=1
20 : M3YGK6_MUSPF 1.00 1.00 2 33 34 65 32 0 0 110 M3YGK6 Uncharacterized protein OS=Mustela putorius furo GN=HCRT PE=4 SV=1
21 : OREX_BOVIN 1.00 1.00 2 33 2 33 32 0 0 33 P56717 Orexin-A OS=Bos taurus GN=HCRT PE=1 SV=1
22 : OREX_CANFA 1.00 1.00 2 33 34 65 32 0 0 130 Q9GLF6 Orexin OS=Canis familiaris GN=HCRT PE=3 SV=1
23 : OREX_HUMAN 1UVQ 1.00 1.00 2 33 35 66 32 0 0 131 O43612 Orexin OS=Homo sapiens GN=HCRT PE=1 SV=1
24 : OREX_MOUSE 1.00 1.00 2 33 34 65 32 0 0 130 O55241 Orexin OS=Mus musculus GN=Hcrt PE=2 SV=1
25 : OREX_PIG 1.00 1.00 2 33 35 66 32 0 0 131 O77668 Orexin OS=Sus scrofa GN=HCRT PE=2 SV=1
26 : OREX_RAT 1.00 1.00 2 33 34 65 32 0 0 130 O55232 Orexin OS=Rattus norvegicus GN=Hcrt PE=1 SV=1
27 : Q547R2_MOUSE 1.00 1.00 2 33 34 65 32 0 0 130 Q547R2 Hypocretin OS=Mus musculus GN=Hcrt PE=2 SV=1
28 : Q8MKI6_BOVIN 1.00 1.00 2 33 35 66 32 0 0 99 Q8MKI6 Prepro-orexin (Fragment) OS=Bos taurus GN=BORX PE=2 SV=1
29 : Q95L34_SHEEP 1.00 1.00 2 33 2 33 32 0 0 66 Q95L34 Orexin A and B (Fragment) OS=Ovis aries PE=4 SV=1
30 : S9WV98_9CETA 1.00 1.00 2 33 39 70 32 0 0 140 S9WV98 Orexin-like protein OS=Camelus ferus GN=CB1_000663013 PE=4 SV=1
31 : G1LHG2_AILME 0.96 0.96 2 29 34 61 28 0 0 61 G1LHG2 Uncharacterized protein OS=Ailuropoda melanoleuca GN=HCRT PE=4 SV=1
32 : F7DMR2_MONDO 0.91 1.00 2 33 34 65 32 0 0 129 F7DMR2 Uncharacterized protein OS=Monodelphis domestica GN=HCRT PE=4 SV=1
33 : G3VQD6_SARHA 0.91 1.00 2 33 35 66 32 0 0 130 G3VQD6 Uncharacterized protein (Fragment) OS=Sarcophilus harrisii GN=HCRT PE=4 SV=1
34 : F1P0W5_CHICK 0.84 0.97 2 33 30 61 32 0 0 148 F1P0W5 Uncharacterized protein OS=Gallus gallus GN=HCRT PE=4 SV=2
35 : Q8AV17_CHICK 0.84 0.97 2 33 30 61 32 0 0 148 Q8AV17 Prepro-orexin OS=Gallus gallus PE=2 SV=1
36 : U3KLG6_FICAL 0.84 0.94 2 33 21 52 32 0 0 146 U3KLG6 Uncharacterized protein (Fragment) OS=Ficedula albicollis GN=HCRT PE=4 SV=1
37 : H1A5Y1_TAEGU 0.81 0.97 2 33 21 52 32 0 0 146 H1A5Y1 Uncharacterized protein (Fragment) OS=Taeniopygia guttata GN=HCRT PE=4 SV=1
38 : H3AFZ2_LATCH 0.78 0.97 2 33 11 42 32 0 0 104 H3AFZ2 Uncharacterized protein (Fragment) OS=Latimeria chalumnae PE=4 SV=1
39 : F6RSC3_CALJA 0.77 0.90 3 33 36 66 31 0 0 131 F6RSC3 Uncharacterized protein OS=Callithrix jacchus GN=HCRT PE=4 SV=1
40 : F6RSD2_CALJA 0.77 0.90 3 33 35 65 31 0 0 130 F6RSD2 Uncharacterized protein OS=Callithrix jacchus GN=HCRT PE=4 SV=1
41 : K7EW59_PELSI 0.75 0.94 2 33 8 39 32 0 0 81 K7EW59 Uncharacterized protein (Fragment) OS=Pelodiscus sinensis GN=HCRT PE=4 SV=1
42 : V8P5T3_OPHHA 0.75 0.97 2 33 26 57 32 0 0 136 V8P5T3 Orexin (Fragment) OS=Ophiophagus hannah GN=HCRT PE=4 SV=1
43 : G1KUK9_ANOCA 0.69 0.94 2 33 27 58 32 0 0 147 G1KUK9 Uncharacterized protein OS=Anolis carolinensis GN=HCRT PE=4 SV=2
44 : E5FCR8_LEUOC 0.68 0.90 3 33 28 58 31 0 0 159 E5FCR8 Preproorexin OS=Leucoraja ocellata PE=2 SV=1
## ALIGNMENTS 1 - 44
SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
1 1 A X 0 0 181 0 0
2 2 A P - 0 0 109 42 64 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPSSNSS SAA
3 3 A L - 0 0 96 45 23 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLMMLLLLVLLMVVV
4 4 A P - 0 0 20 45 0 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP
5 5 A D S >> S+ 0 0 116 45 44 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDNNEEHHEDDVDDK
6 6 A a H 3>>S+ 0 0 12 45 2 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCSCCCCCCCCCCCCC
7 7 A b H 345S+ 0 0 61 45 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
8 8 A R H <45S+ 0 0 198 45 22 RRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRHRRRRRC
9 9 A Q H <5S- 0 0 151 45 0 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
10 10 A K T <5 + 0 0 182 45 9 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKQ
11 11 A T S S+ 0 0 36 45 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
15 15 A R T 3> S+ 0 0 186 45 18 RRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRNK
16 16 A L H 3> S+ 0 0 63 45 57 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLIIVVIRRVIIV
17 17 A Y H <> S+ 0 0 89 45 13 YYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYFFI
18 18 A E H > S+ 0 0 84 45 28 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDDDDDDNEEDDDD
19 19 A L H X S+ 0 0 117 45 4 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLVLLL
20 20 A L H X S+ 0 0 106 45 0 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
21 21 A H H < S+ 0 0 80 45 9 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHR
22 22 A G H < S+ 0 0 58 45 24 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGRRGGGG
23 23 A A H < S- 0 0 99 45 78 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAMMMMNGGLMTT
24 24 A G X + 0 0 28 45 0 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
25 25 A N H >> S+ 0 0 84 45 0 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
26 26 A H H 3> S+ 0 0 134 45 0 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
27 27 A A H 3> S+ 0 0 64 45 0 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
28 28 A A H