Complet list of 1wi0 hssp file
Complete list of 1wi0.hssp file
HSSP HOMOLOGY DERIVED SECONDARY STRUCTURE OF PROTEINS , VERSION 2.0 2011
PDBID 1WI0
THRESHOLD according to: t(L)=(290.15 * L ** -0.562) + 5
REFERENCE Sander C., Schneider R. : Database of homology-derived protein structures. Proteins, 9:56-68 (1991).
CONTACT Maintained at http://www.cmbi.ru.nl/ by Maarten L. Hekkelman
DATE file generated on 2014-05-12
HEADER TRANSFERASE 28-MAY-04 1WI0
COMPND MOL_ID: 1; MOLECULE: MITOGEN ACTIVATED PROTEIN KINASE KINASE 5; CHAIN:
SOURCE MOL_ID: 1; ORGANISM_SCIENTIFIC: MUS MUSCULUS; ORGANISM_COMMON: HOUSE M
AUTHOR M.YONEYAMA,F.HAYASHI,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA, S.YOKOYAMA,R
DBREF 1WI0 A 8 107 UNP Q9WVS7 MP2K5_MOUSE 8 107
SEQLENGTH 113
NCHAIN 1 chain(s) in 1WI0 data set
NALIGN 72
NOTATION : ID: EMBL/SWISSPROT identifier of the aligned (homologous) protein
NOTATION : STRID: if the 3-D structure of the aligned protein is known, then STRID is the Protein Data Bank identifier as taken
NOTATION : from the database reference or DR-line of the EMBL/SWISSPROT entry
NOTATION : %IDE: percentage of residue identity of the alignment
NOTATION : %SIM (%WSIM): (weighted) similarity of the alignment
NOTATION : IFIR/ILAS: first and last residue of the alignment in the test sequence
NOTATION : JFIR/JLAS: first and last residue of the alignment in the alignend protein
NOTATION : LALI: length of the alignment excluding insertions and deletions
NOTATION : NGAP: number of insertions and deletions in the alignment
NOTATION : LGAP: total length of all insertions and deletions
NOTATION : LSEQ2: length of the entire sequence of the aligned protein
NOTATION : ACCNUM: SwissProt accession number
NOTATION : PROTEIN: one-line description of aligned protein
NOTATION : SeqNo,PDBNo,AA,STRUCTURE,BP1,BP2,ACC: sequential and PDB residue numbers, amino acid (lower case = Cys), secondary
NOTATION : structure, bridge partners, solvent exposure as in DSSP (Kabsch and Sander, Biopolymers 22, 2577-2637(1983)
NOTATION : VAR: sequence variability on a scale of 0-100 as derived from the NALIGN alignments
NOTATION : pair of lower case characters (AvaK) in the alignend sequence bracket a point of insertion in this sequence
NOTATION : dots (....) in the alignend sequence indicate points of deletion in this sequence
NOTATION : SEQUENCE PROFILE: relative frequency of an amino acid type at each position. Asx and Glx are in their
NOTATION : acid/amide form in proportion to their database frequencies
NOTATION : NOCC: number of aligned sequences spanning this position (including the test sequence)
NOTATION : NDEL: number of sequences with a deletion in the test protein at this position
NOTATION : NINS: number of sequences with an insertion in the test protein at this position
NOTATION : ENTROPY: entropy measure of sequence variability at this position
NOTATION : RELENT: relative entropy, i.e. entropy normalized to the range 0-100
NOTATION : WEIGHT: conservation weight
## PROTEINS : identifier and alignment statistics
NR. ID STRID %IDE %WSIM IFIR ILAS JFIR JLAS LALI NGAP LGAP LSEQ2 ACCNUM PROTEIN
1 : L9KHH5_TUPCH 0.97 0.98 8 107 8 107 100 0 0 318 L9KHH5 Dual specificity mitogen-activated protein kinase kinase 5 OS=Tupaia chinensis GN=TREES_T100014181 PE=4 SV=1
2 : MP2K5_MOUSE 1WI0 0.95 0.98 7 113 7 113 107 0 0 448 Q9WVS7 Dual specificity mitogen-activated protein kinase kinase 5 OS=Mus musculus GN=Map2k5 PE=1 SV=1
3 : Q3TM51_MOUSE 0.95 0.98 8 113 8 113 106 0 0 261 Q3TM51 Putative uncharacterized protein (Fragment) OS=Mus musculus GN=Map2k5 PE=2 SV=1
4 : B2RD76_HUMAN 0.94 0.97 7 113 7 113 107 0 0 448 B2RD76 cDNA, FLJ96491, highly similar to Homo sapiens mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant A, mRNA OS=Homo sapiens PE=2 SV=1
5 : D2I114_AILME 0.94 0.97 8 113 8 113 106 0 0 349 D2I114 Putative uncharacterized protein (Fragment) OS=Ailuropoda melanoleuca GN=PANDA_018945 PE=4 SV=1
6 : F1PQU8_CANFA 0.94 0.97 7 113 7 113 107 0 0 362 F1PQU8 Uncharacterized protein OS=Canis familiaris GN=MAP2K5 PE=4 SV=2
7 : F7BQY5_HORSE 0.94 0.97 7 113 7 113 107 0 0 463 F7BQY5 Uncharacterized protein OS=Equus caballus GN=MAP2K5 PE=4 SV=1
8 : F7EJT6_CALJA 0.94 0.97 7 113 7 113 107 0 0 448 F7EJT6 Dual specificity mitogen-activated protein kinase kinase 5 isoform A OS=Callithrix jacchus GN=MAP2K5 PE=2 SV=1
9 : F7GFU7_CALJA 0.94 0.97 7 113 7 113 107 0 0 438 F7GFU7 Dual specificity mitogen-activated protein kinase kinase 5 isoform B OS=Callithrix jacchus GN=MAP2K5 PE=2 SV=1
10 : F7GJH7_MACMU 0.94 0.97 7 113 7 113 107 0 0 449 F7GJH7 Uncharacterized protein OS=Macaca mulatta GN=MAP2K5 PE=4 SV=1
11 : F7GJI0_MACMU 0.94 0.97 7 113 7 113 107 0 0 475 F7GJI0 Uncharacterized protein OS=Macaca mulatta GN=MAP2K5 PE=4 SV=1
12 : G1LEH7_AILME 0.94 0.97 7 113 7 113 107 0 0 448 G1LEH7 Uncharacterized protein OS=Ailuropoda melanoleuca GN=MAP2K5 PE=4 SV=1
13 : G1LEH9_AILME 0.94 0.97 7 113 7 113 107 0 0 363 G1LEH9 Uncharacterized protein OS=Ailuropoda melanoleuca GN=MAP2K5 PE=4 SV=1
14 : G3H8P6_CRIGR 0.94 0.97 7 113 7 113 107 0 0 719 G3H8P6 Dual specificity mitogen-activated protein kinase kinase 5 OS=Cricetulus griseus GN=I79_006754 PE=4 SV=1
15 : G3QPY6_GORGO 0.94 0.97 7 113 7 113 107 0 0 448 G3QPY6 Uncharacterized protein OS=Gorilla gorilla gorilla GN=101137194 PE=4 SV=1
16 : G7MXW8_MACMU 0.94 0.97 7 113 7 113 107 0 0 448 G7MXW8 Dual specificity mitogen-activated protein kinase kinase 5 OS=Macaca mulatta GN=EGK_17622 PE=4 SV=1
17 : G7P8W8_MACFA 0.94 0.97 7 113 7 113 107 0 0 448 G7P8W8 Dual specificity mitogen-activated protein kinase kinase 5 OS=Macaca fascicularis GN=EGM_16077 PE=4 SV=1
18 : H0WKU1_OTOGA 0.94 0.97 7 113 7 113 107 0 0 358 H0WKU1 Uncharacterized protein OS=Otolemur garnettii GN=MAP2K5 PE=4 SV=1
19 : H2NNK7_PONAB 0.94 0.97 7 113 7 113 107 0 0 448 H2NNK7 Uncharacterized protein OS=Pongo abelii GN=MAP2K5 PE=4 SV=1
20 : H2Q9P0_PANTR 0.94 0.97 7 113 7 113 107 0 0 448 H2Q9P0 Mitogen-activated protein kinase kinase 5 OS=Pan troglodytes GN=MAP2K5 PE=2 SV=1
21 : H9EPL8_MACMU 0.94 0.97 7 113 7 113 107 0 0 448 H9EPL8 Dual specificity mitogen-activated protein kinase kinase 5 isoform A OS=Macaca mulatta GN=MAP2K5 PE=2 SV=1
22 : I3MFA0_SPETR 0.94 0.97 7 113 7 113 107 0 0 448 I3MFA0 Uncharacterized protein OS=Spermophilus tridecemlineatus GN=MAP2K5 PE=4 SV=1
23 : J9P3W4_CANFA 0.94 0.97 7 113 7 113 107 0 0 448 J9P3W4 Uncharacterized protein OS=Canis familiaris GN=MAP2K5 PE=4 SV=1
24 : K7CUU8_PANTR 0.94 0.97 7 113 7 113 107 0 0 438 K7CUU8 Mitogen-activated protein kinase kinase 5 OS=Pan troglodytes GN=MAP2K5 PE=2 SV=1
25 : L5K138_PTEAL 0.94 0.97 7 113 7 113 107 0 0 1243 L5K138 Ladybird homeobox corepressor 1 OS=Pteropus alecto GN=PAL_GLEAN10023345 PE=4 SV=1
26 : MP2K5_HUMAN 4IC7 0.94 0.97 7 113 7 113 107 0 0 448 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 OS=Homo sapiens GN=MAP2K5 PE=1 SV=2
27 : MP2K5_RAT 0.94 0.97 7 113 7 113 107 0 0 448 Q62862 Dual specificity mitogen-activated protein kinase kinase 5 OS=Rattus norvegicus GN=Map2k5 PE=1 SV=1
28 : U6CUJ9_NEOVI 0.94 0.97 7 113 7 113 107 0 0 448 U6CUJ9 Dual specificity mitogen-activated protein kinase kinase 5 OS=Neovison vison GN=MP2K5 PE=2 SV=1
29 : E1BI01_BOVIN 0.93 0.97 7 113 7 113 107 0 0 447 E1BI01 Uncharacterized protein OS=Bos taurus GN=MAP2K5 PE=4 SV=2
30 : F1SJH7_PIG 0.93 0.97 8 113 8 113 106 0 0 136 F1SJH7 Uncharacterized protein OS=Sus scrofa GN=LOC100518642 PE=4 SV=2
31 : G1RRK9_NOMLE 0.93 0.97 7 113 7 113 107 0 0 505 G1RRK9 Uncharacterized protein OS=Nomascus leucogenys GN=MAP2K5 PE=4 SV=2
32 : G1SWD5_RABIT 0.93 0.96 7 113 7 113 107 0 0 448 G1SWD5 Uncharacterized protein OS=Oryctolagus cuniculus GN=MAP2K5 PE=4 SV=1
33 : G3SNJ6_LOXAF 0.93 0.96 7 113 7 113 107 0 0 446 G3SNJ6 Uncharacterized protein OS=Loxodonta africana GN=MAP2K5 PE=4 SV=1
34 : G5C5F7_HETGA 0.93 0.98 7 113 7 113 107 0 0 448 G5C5F7 Dual specificity mitogen-activated protein kinase kinase 5 OS=Heterocephalus glaber GN=GW7_10526 PE=4 SV=1
35 : H0UV50_CAVPO 0.93 0.97 7 113 7 113 107 0 0 448 H0UV50 Uncharacterized protein OS=Cavia porcellus GN=MAP2K5 PE=4 SV=1
36 : K9IXV5_DESRO 0.93 0.96 7 113 7 113 107 0 0 448 K9IXV5 Putative dual specificity mitogen-activated protein kinase kinase 5 OS=Desmodus rotundus PE=2 SV=1
37 : L8ISI3_9CETA 0.93 0.97 7 113 7 113 107 0 0 448 L8ISI3 Dual specificity mitogen-activated protein kinase kinase 5 OS=Bos mutus GN=M91_20545 PE=4 SV=1
38 : Q2PFR6_MACFA 0.93 0.96 7 113 7 113 107 0 0 448 Q2PFR6 Putative uncharacterized protein OS=Macaca fascicularis PE=2 SV=1
39 : W5QAG1_SHEEP 0.93 0.97 7 113 7 113 107 0 0 448 W5QAG1 Uncharacterized protein OS=Ovis aries GN=MAP2K5 PE=4 SV=1
40 : G3WNC5_SARHA 0.91 0.96 7 113 7 113 107 0 0 448 G3WNC5 Uncharacterized protein OS=Sarcophilus harrisii GN=MAP2K5 PE=4 SV=1
41 : F1NU31_CHICK 0.90 0.98 16 113 106 203 98 0 0 538 F1NU31 Uncharacterized protein OS=Gallus gallus GN=MAP2K5 PE=4 SV=2
42 : G1NC84_MELGA 0.88 0.97 12 113 12 113 102 0 0 449 G1NC84 Uncharacterized protein (Fragment) OS=Meleagris gallopavo GN=MAP2K5 PE=4 SV=1
43 : H3AXL0_LATCH 0.83 0.95 9 113 9 113 105 0 0 448 H3AXL0 Uncharacterized protein OS=Latimeria chalumnae PE=4 SV=1
44 : U3F8I6_MICFL 0.83 0.95 17 113 18 115 98 1 1 451 U3F8I6 Mitogen-activated protein kinase 5 OS=Micrurus fulvius PE=2 SV=1
45 : W5N958_LEPOC 0.82 0.92 9 113 9 113 105 0 0 452 W5N958 Uncharacterized protein OS=Lepisosteus oculatus PE=4 SV=1
46 : V9KIS1_CALMI 0.77 0.94 17 113 13 109 97 0 0 455 V9KIS1 Dual specificity mitogen-activated protein kinase kinase 5 OS=Callorhynchus milii PE=2 SV=1
47 : F6YUW6_XENTR 0.76 0.91 15 113 15 113 99 0 0 449 F6YUW6 Uncharacterized protein OS=Xenopus tropicalis GN=map2k5 PE=4 SV=1
48 : F7DKW3_XENTR 0.76 0.91 15 113 15 113 99 0 0 449 F7DKW3 Uncharacterized protein OS=Xenopus tropicalis GN=map2k5 PE=4 SV=1
49 : Q28G43_XENTR 0.76 0.91 15 113 15 113 99 0 0 448 Q28G43 Mitogen-activated protein kinase kinase 5 OS=Xenopus tropicalis GN=map2k5 PE=2 SV=1
50 : Q6NTN3_XENLA 0.76 0.92 15 113 15 113 99 0 0 448 Q6NTN3 MEK5 OS=Xenopus laevis GN=map2k5 PE=2 SV=1
51 : V9KTR9_CALMI 0.76 0.93 17 113 13 109 97 0 0 475 V9KTR9 Dual specificity mitogen-activated protein kinase kinase 5 OS=Callorhynchus milii PE=2 SV=1
52 : U3KEP0_FICAL 0.75 0.88 11 113 11 114 104 1 1 344 U3KEP0 Uncharacterized protein OS=Ficedula albicollis GN=MAP2K5 PE=4 SV=1
53 : S4R6V1_PETMA 0.65 0.89 13 113 14 114 101 0 0 146 S4R6V1 Uncharacterized protein (Fragment) OS=Petromyzon marinus PE=4 SV=1
54 : A9JRD0_DANRE 0.62 0.79 12 113 12 112 102 1 1 450 A9JRD0 Uncharacterized protein OS=Danio rerio GN=map2k5 PE=2 SV=1
55 : B1NA67_DANRE 0.62 0.79 12 113 12 112 102 1 1 449 B1NA67 Mitogen-activated protein kinase kinase 5 OS=Danio rerio GN=map2k5 PE=2 SV=1
56 : H2L9Y6_ORYLA 0.61 0.81 12 113 12 112 102 1 1 446 H2L9Y6 Uncharacterized protein (Fragment) OS=Oryzias latipes GN=LOC101169919 PE=4 SV=1
57 : H2L9Y8_ORYLA 0.61 0.81 12 113 12 112 102 1 1 436 H2L9Y8 Uncharacterized protein (Fragment) OS=Oryzias latipes GN=LOC101169919 PE=4 SV=1
58 : C3KIA3_ANOFI 0.60 0.79 12 113 12 112 102 1 1 283 C3KIA3 Dual specificity mitogen-activated protein kinase kinase 5 OS=Anoplopoma fimbria GN=MP2K5 PE=2 SV=1
59 : H2L9Z2_ORYLA 0.60 0.80 12 113 12 112 102 1 1 261 H2L9Z2 Uncharacterized protein (Fragment) OS=Oryzias latipes GN=LOC101169919 PE=4 SV=1
60 : I3K6D7_ORENI 0.60 0.80 15 113 15 112 99 1 1 449 I3K6D7 Uncharacterized protein (Fragment) OS=Oreochromis niloticus GN=map2k5 PE=4 SV=1
61 : M3ZJM6_XIPMA 0.60 0.80 15 113 13 110 99 1 1 444 M3ZJM6 Uncharacterized protein OS=Xiphophorus maculatus PE=4 SV=1
62 : C3KK10_ANOFI 0.59 0.80 12 113 12 112 102 1 1 283 C3KK10 Dual specificity mitogen-activated protein kinase kinase 5 OS=Anoplopoma fimbria GN=MP2K5 PE=2 SV=1
63 : C3ZXK9_BRAFL 0.59 0.77 9 113 1 104 105 1 1 246 C3ZXK9 Putative uncharacterized protein (Fragment) OS=Branchiostoma floridae GN=BRAFLDRAFT_217608 PE=4 SV=1
64 : G3PXG9_GASAC 0.59 0.81 11 113 11 112 103 1 1 432 G3PXG9 Uncharacterized protein (Fragment) OS=Gasterosteus aculeatus PE=4 SV=1
65 : H3CVY6_TETNG 0.59 0.77 12 113 5 105 102 1 1 436 H3CVY6 Uncharacterized protein (Fragment) OS=Tetraodon nigroviridis PE=4 SV=1
66 : H2V1U6_TAKRU 0.57 0.76 11 113 1 102 103 1 1 433 H2V1U6 Uncharacterized protein (Fragment) OS=Takifugu rubripes GN=LOC101078396 PE=4 SV=1
67 : W4Y123_STRPU 0.55 0.73 12 107 1 95 96 1 1 309 W4Y123 Uncharacterized protein OS=Strongylocentrotus purpuratus GN=Sp-Map2k5_1 PE=4 SV=1
68 : W5KFH8_ASTMX 0.52 0.72 12 107 12 106 96 1 1 442 W5KFH8 Uncharacterized protein OS=Astyanax mexicanus PE=4 SV=1
69 : A7S6F5_NEMVE 0.47 0.71 18 112 8 100 95 1 2 450 A7S6F5 Predicted protein OS=Nematostella vectensis GN=v1g106419 PE=4 SV=1
70 : R7UF31_CAPTE 0.43 0.68 12 112 1 99 101 2 2 434 R7UF31 Uncharacterized protein OS=Capitella teleta GN=CAPTEDRAFT_173814 PE=4 SV=1
71 : V4B2E8_LOTGI 0.41 0.69 12 112 1 100 101 1 1 432 V4B2E8 Uncharacterized protein OS=Lottia gigantea GN=LOTGIDRAFT_157785 PE=4 SV=1
72 : K1RIQ1_CRAGI 0.31 0.57 6 112 261 356 107 2 11 672 K1RIQ1 Dual specificity mitogen-activated protein kinase kinase 5 OS=Crassostrea gigas GN=CGI_10009421 PE=4 SV=1
## ALIGNMENTS 1 - 70
SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
1 1 A G 0 0 84 1 0
2 2 A S - 0 0 70 1 0
3 3 A S S S+ 0 0 131 1 0
4 4 A G + 0 0 66 1 0
5 5 A S - 0 0 90 1 0
6 6 A S + 0 0 114 2 0
7 7 A G S > S- 0 0 45 38 44 G G GGGGGGGGGGGGGGGGGGGGGGGG GGGGGGGGGG
8 8 A P T 3 S+ 0 0 134 42 43 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP
9 9 A F T 3 S- 0 0 194 45 17 FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFVFYYFFFFS F F F
10 10 A C < - 0 0 61 45 86 HCCPHHRPPPPHHPPPPHPPPRHPHPRHHHPHHCLHHPHH N S S
11 11 A A + 0 0 89 48 31 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA E D A PA E
12 12 A M - 0 0 78 61 0 MMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMM MM M M MMMMMM MMMMMMM M
13 13 A E S S+ 0 0 211 62 45 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDEEEEE SE E DDEEDDDD DADDDAD A
14 14 A N S S- 0 0 95 62 68 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNN HN N SESSNNTN AATAAAT C
15 15 A Q - 0 0 150 68 53 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ QQ Q QQQQ QREEEEEEEEEQEVVQE P
16 16 A V - 0 0 51 69 78 MVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVL T AAAA ATGGAAAAAPAPAPPPA P
17 17 A L E -A 33 0A 0 72 37 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLIIIIIIIIIFIIILI I
18 18 A V E -A 32 0A 47 73 20 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVT
19 19 A I E -Ab 31 102A 0 73 6 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
20 20 A R E -Ab 30 103A 79 73 4 RRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRR
21 21 A I E -Ab 29 104A 0 73 0 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
22 22 A K E -A 28 0A 76 73 41 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRRRRRRHKKKKKKKKKKSIKKKKIM
23 23 A I > - 0 0 21 73 69 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIGIIIIGITTTTTTTTTTVTTTTTPT
24 24 A P T 3 S- 0 0 83 72 31 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP.PPPPQPPPQPEG
25 25 A N T 3 S+ 0 0 170 73 77 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNDDDDDDEDDDDEDDVVLLPLSLAESTAHVDE
26 26 A S S < S- 0 0 93 73 46 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSRSSSGGGGgGGGGGGGGGGGGGAGGGGGGGGGGGG
27 27 A G - 0 0 52 60 38 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGgGGGGGGGAN....GD..DE...E...
28 28 A A E -A 22 0A 38 70 58 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAADADDAAAADADDDDDDMDD.EDDDDD.A
29 29 A V E -A 21 0A 70 72 46 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVMMMMMDMMMVMMMVMKM
30 30 A D E -A 20 0A 99 71 5 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD.DDDDDDDDDAD
31 31 A W E -A 19 0A 45 72 51 WWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWSSSSSSSSSWSSSWSVW
32 32 A T E -A 18 0A 80 72 63 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTSTTTTSTSPPSSASSSAAASSTSDA
33 33 A V E +A 17 0A 5 72 11 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVIVVVVIVVVVVVVVVVVVVVVVVWV
34 34 A H S S+ 0 0 90 71 63 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHNHHHHHHHHPPQQQQPHDDDDDDDDDDEDDD.DAE
35 35 A S + 0 0 21 72 57 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTPSPPPPPPSPSSSSCSCYCSSCCQCVQ
36 36 A G S S+ 0 0 0 72 73 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAAAAVAAAAAAAIPPAAPAPPP.PPPLPNP
37 37 A P S S+ 0 0 80 73 69 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPSPSSTTTTSPPSSSSASSSALASFGSPQ
38 38 A Q S S+ 0 0 127 73 68 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHHLLLLLVLQLLLQLTD
39 39 A L - 0 0 6 73 17 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLPLLLLLLLLLLLLLLLLLIL
40 40 A L > - 0 0 82 73 82 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLILLLLLLLYNNNNNNNNNSNNNSSTL
41 41 A F H > S+ 0 0 20 73 15 FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
42 42 A R H > S+ 0 0 171 73 60 RRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRNNNNNNNNNRNNNHNRS
43 43 A D H > S+ 0 0 20 73 15 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDQ
44 44 A V H X S+ 0 0 0 72 33 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVIIIIVVVLLLLLLLLLVLLLVLVV
45 45 A L H X S+ 0 0 26 73 10 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLMMLMLLLLLLLLLLL
46 46 A D H < S+ 0 0 95 73 69 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDVDAAVVVVVVVDVVVEVEE
47 47 A V H >X S+ 0 0 28 73 60 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVRVAAAAAAAAAVAAAVAAA
48 48 A I H >X S+ 0 0 0 73 2 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIL
49 49 A G H 3< S+ 0 0 37 73 78 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGSSGGGGGGDSRRRRRRRRRGRRRARSS
50 50 A Q H <4 S+ 0 0 165 73 35 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQKQDDDDDDDDDRDDDQDQQ
51 51 A V H << S+ 0 0 34 73 16 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVNVAAVVVVVVVIVVVVVVI
52 52 A L >< + 0 0 14 73 22 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLILALMMMMMMMMMLMMMLMMK
53 53 A P T 3 S+ 0 0 99 73 13 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPQPPS
54 54 A E T 3 S+ 0 0 193 73 26 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDDDDDDDDDDDDPEEEEEEEEEEDEEEDEHE
55 55 A A S < S- 0 0 30 73 32 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATAATAAAATGAAAAAAAAAAVAAANAAL
56 56 A T + 0 0 60 73 14 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTQ
57 57 A T + 0 0 9 73 66 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTATVVVVVVVVVTVVVPIAN
58 58 A T S S+ 0 0 83 73 19 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTPTTTTTTTTTTTTTTATTS
59 59 A A - 0 0 4 73 8 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAVAAAAAAAAAAAAAAAAAA
60 60 A F E -CD 72 106A 0 73 9 FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFfFFFFFFFFFFFFFFFFFF
61 61 A E E -CD 71 105A 55 72 2 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEeEEEEEEEEEEEEEEEEDE
62 62 A Y E -CD 70 104A 12 72 0 YYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYY
63 63 A E - 0 0 69 73 7 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEV
64 64 A D > - 0 0 41 73 0 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
65 65 A E T 3 S+ 0 0 156 73 0 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE
66 66 A D T 3 S- 0 0 138 73 59 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDVVVVVVVVVDVVVDVED
67 67 A G < + 0 0 38 73 15 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGKG
68 68 A D - 0 0 126 73 4 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDE
69 69 A R - 0 0 108 73 0 RRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRR
70 70 A I E -C 62 0A 52 73 1 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
71 71 A T E -C 61 0A 37 73 0 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
72 72 A V E +C 60 0A 0 73 0 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVV
73 73 A R S S+ 0 0 185 73 0 RRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRR
74 74 A S S >> S- 0 0 41 73 4 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS
75 75 A D H 3> S+ 0 0 54 73 2 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDE
76 76 A E H 3> S+ 0 0 158 73 7 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDDDEEEEEEEEEEEDEEE
77 77 A E H <> S+ 0 0 57 73 0 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE
78 78 A M H X S+ 0 0 0 73 7 MMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMLLLLLLLLLMLLLMLLM
79 79 A K H X S+ 0 0 128 73 27 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKQKKKEKQT
80 80 A A H X S+ 0 0 48 73 10 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAS
81 81 A M H X S+ 0 0 0 73 0 MMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMM
82 82 A L H X S+ 0 0 6 73 10 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLMLLVILIL
83 83 A S H X S+ 0 0 86 73 24 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSASSSSSSSSSSSSSNSNS
84 84 A Y H X S+ 0 0 45 73 34 YYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYGQ
85 85 A Y H X S+ 0 0 21 73 0 YYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYY
86 86 A Y H X S+ 0 0 56 73 41 YYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYCCCCYYLCCLLFLCCFVFCCLCFI
87 87 A S H < S+ 0 0 66 73 69 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTNTTTTSTSGNNNNNNNNNNNNNSNWG
88 88 A T H >X S+ 0 0 34 73 42 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTMMMMTTTTTTTTTTTTQTTTLKYS
89 89 A V H >X S+ 0 0 13 73 36 VVVVVVVVVVVVVVVVVVVVVVVVVVVVIIIVVVVVIVIVVVVVVVVVVVVVMVVVVMVMMMIMMMLLYL
90 90 A M H 3X S+ 0 0 103 73 90 MMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMTLLLLTMHMMNNNNNNNSNNNANSP
91 91 A E H <> S+ 0 0 96 73 7 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEGEEEEEEEEEEEEEEDEEEEEEEEEEEEEEEEK
92 92 A Q H S- 0 0 45 38 44 E
8 8 A P T 3 S+ 0 0 134 42 43 A
9 9 A F T 3 S- 0 0 194 45 17 L
10 10 A C < - 0 0 61 45 86 E
11 11 A A + 0 0 89 48 31 A
12 12 A M - 0 0 78 61 0 MM
13 13 A E S S+ 0 0 211 62 45 NS
14 14 A N S S- 0 0 95 62 68 ET
15 15 A Q - 0 0 150 68 53 PG
16 16 A V - 0 0 51 69 78 PC
17 17 A L E -A 33 0A 0 72 37 FN
18 18 A V E -A 32 0A 47 73 20 TR
19 19 A I E -Ab 31 102A 0 73 6 LL
20 20 A R E -Ab 30 103A 79 73 4 RH
21 21 A I E -Ab 29 104A 0 73 0 II
22 22 A K E -A 28 0A 76 73 41 HN
23 23 A I > - 0 0 21 73 69 VK
24 24 A P T 3 S- 0 0 83 72 31 EC
25 25 A N T 3 S+ 0 0 170 73 77 GN
26 26 A S S < S- 0 0 93 73 46 QG
27 27 A G - 0 0 52 60 38 Q.
28 28 A A E -A 22 0A 38 70 58 D.
29 29 A V E -A 21 0A 70 72 46 M.
30 30 A D E -A 20 0A 99 71 5 D.
31 31 A W E -A 19 0A 45 72 51 W.
32 32 A T E -A 18 0A 80 72 63 M.
33 33 A V E +A 17 0A 5 72 11 V.
34 34 A H S S+ 0 0 90 71 63 Q.
35 35 A S + 0 0 21 72 57 P.
36 36 A G S S+ 0 0 0 72 73 EM
37 37 A P S S+ 0 0 80 73 69 DG
38 38 A Q S S+ 0 0 127 73 68 VE
39 39 A L - 0 0 6 73 17 TI
40 40 A L > - 0 0 82 73 82 FM
41 41 A F H > S+ 0 0 20 73 15 QM
42 42 A R H > S+ 0 0 171 73 60 RD
43 43 A D H > S+ 0 0 20 73 15 TQ
44 44 A V H X S+ 0 0 0 72 33 .A
45 45 A L H X S+ 0 0 26 73 10 LR
46 46 A D H < S+ 0 0 95 73 69 EV
47 47 A V H >X S+ 0 0 28 73 60 VQ
48 48 A I H >X S+ 0 0 0 73 2 II
49 49 A G H 3< S+ 0 0 37 73 78 SP
50 50 A Q H <4 S+ 0 0 165 73 35 QE
51 51 A V H << S+ 0 0 34 73 16 LV
52 52 A L >< + 0 0 14 73 22 LI
53 53 A P T 3 S+ 0 0 99 73 13 PA
54 54 A E T 3 S+ 0 0 193 73 26 HQ
55 55 A A S < S- 0 0 30 73 32 SV
56 56 A T + 0 0 60 73 14 TL
57 57 A T + 0 0 9 73 66 IP
58 58 A T S S+ 0 0 83 73 19 TQ
59 59 A A - 0 0 4 73 8 AT
60 60 A F E -CD 72 106A 0 73 9 FN
61 61 A E E -CD 71 105A 55 72 2 E.
62 62 A Y E -CD 70 104A 12 72 0 Y.
63 63 A E - 0 0 69 73 7 EE
64 64 A D > - 0 0 41 73 0 DD
65 65 A E T 3 S+ 0 0 156 73 0 EE
66 66 A D T 3 S- 0 0 138 73 59 DD
67 67 A G < + 0 0 38 73 15 ND
68 68 A D - 0 0 126 73 4 DE
69 69 A R - 0 0 108 73 0 RR
70 70 A I E -C 62 0A 52 73 1 VI
71 71 A T E -C 61 0A 37 73 0 TT
72 72 A V E +C 60 0A 0 73 0 VV
73 73 A R S S+ 0 0 185 73 0 RR
74 74 A S S >> S- 0 0 41 73 4 GS
75 75 A D H 3> S+ 0 0 54 73 2 DD
76 76 A E H 3> S+ 0 0 158 73 7 DE
77 77 A E H <> S+ 0 0 57 73 0 EE
78 78 A M H X S+ 0 0 0 73 7 MM
79 79 A K H X S+ 0 0 128 73 27 RA
80 80 A A H X S+ 0 0 48 73 10 NA
81 81 A M H X S+ 0 0 0 73 0 MM
82 82 A L H X S+ 0 0 6 73 10 FF
83 83 A S H X S+ 0 0 86 73 24 AQ
84 84 A Y H X S+ 0 0 45 73 34 DA
85 85 A Y H X S+ 0 0 21 73 0 YY
86 86 A Y H X S+ 0 0 56 73 41 FF
87 87 A S H < S+ 0 0 66 73 69 TE
88 88 A T H >X S+ 0 0 34 73 42 ET
89 89 A V H >X S+ 0 0 13 73 36 LL
90 90 A M H 3X S+ 0 0 103 73 90 SS
91 91 A E H <> S+ 0 0 96 73 7 EE
92 92 A Q H