Complet list of 1vyn hssp file
Complete list of 1vyn.hssp file
HSSP HOMOLOGY DERIVED SECONDARY STRUCTURE OF PROTEINS , VERSION 2.0 2011
PDBID 1VYN
THRESHOLD according to: t(L)=(290.15 * L ** -0.562) + 5
REFERENCE Sander C., Schneider R. : Database of homology-derived protein structures. Proteins, 9:56-68 (1991).
CONTACT Maintained at http://www.cmbi.ru.nl/ by Maarten L. Hekkelman
DATE file generated on 2014-05-11
HEADER NUCLEIC ACID BINDING 03-MAY-04 1VYN
COMPND MOL_ID: 1; MOLECULE: ARGONAUTE2; CHAIN: A; FRAGMENT: PAZ DOMAIN, RESID
SOURCE MOL_ID: 1; ORGANISM_SCIENTIFIC: DROSOPHILA MELANOGASTER; ORGANISM_COMM
AUTHOR A.LINGEL,B.SIMON,E.IZAURRALDE,M.SATTLER
DBREF 1VYN A 1 4 PDB 1VYN 1VYN 1 4
DBREF 1VYN A 5 143 UNP Q9VUQ5 Q9VUQ5 605 743
SEQLENGTH 117
NCHAIN 1 chain(s) in 1VYN data set
NALIGN 46
NOTATION : ID: EMBL/SWISSPROT identifier of the aligned (homologous) protein
NOTATION : STRID: if the 3-D structure of the aligned protein is known, then STRID is the Protein Data Bank identifier as taken
NOTATION : from the database reference or DR-line of the EMBL/SWISSPROT entry
NOTATION : %IDE: percentage of residue identity of the alignment
NOTATION : %SIM (%WSIM): (weighted) similarity of the alignment
NOTATION : IFIR/ILAS: first and last residue of the alignment in the test sequence
NOTATION : JFIR/JLAS: first and last residue of the alignment in the alignend protein
NOTATION : LALI: length of the alignment excluding insertions and deletions
NOTATION : NGAP: number of insertions and deletions in the alignment
NOTATION : LGAP: total length of all insertions and deletions
NOTATION : LSEQ2: length of the entire sequence of the aligned protein
NOTATION : ACCNUM: SwissProt accession number
NOTATION : PROTEIN: one-line description of aligned protein
NOTATION : SeqNo,PDBNo,AA,STRUCTURE,BP1,BP2,ACC: sequential and PDB residue numbers, amino acid (lower case = Cys), secondary
NOTATION : structure, bridge partners, solvent exposure as in DSSP (Kabsch and Sander, Biopolymers 22, 2577-2637(1983)
NOTATION : VAR: sequence variability on a scale of 0-100 as derived from the NALIGN alignments
NOTATION : pair of lower case characters (AvaK) in the alignend sequence bracket a point of insertion in this sequence
NOTATION : dots (....) in the alignend sequence indicate points of deletion in this sequence
NOTATION : SEQUENCE PROFILE: relative frequency of an amino acid type at each position. Asx and Glx are in their
NOTATION : acid/amide form in proportion to their database frequencies
NOTATION : NOCC: number of aligned sequences spanning this position (including the test sequence)
NOTATION : NDEL: number of sequences with a deletion in the test protein at this position
NOTATION : NINS: number of sequences with an insertion in the test protein at this position
NOTATION : ENTROPY: entropy measure of sequence variability at this position
NOTATION : RELENT: relative entropy, i.e. entropy normalized to the range 0-100
NOTATION : WEIGHT: conservation weight
## PROTEINS : identifier and alignment statistics
NR. ID STRID %IDE %WSIM IFIR ILAS JFIR JLAS LALI NGAP LGAP LSEQ2 ACCNUM PROTEIN
1 : AGO2_DROME 3MJ0 0.99 1.00 1 117 601 717 117 0 0 1214 Q9VUQ5 Protein argonaute-2 OS=Drosophila melanogaster GN=AGO2 PE=1 SV=3
2 : E5KZ94_DROME 0.99 1.00 1 117 204 320 117 0 0 817 E5KZ94 AGO2 (Fragment) OS=Drosophila melanogaster PE=4 SV=1
3 : M9PFK7_DROME 0.99 1.00 1 117 174 290 117 0 0 787 M9PFK7 Argonaute 2, isoform E OS=Drosophila melanogaster GN=AGO2 PE=4 SV=1
4 : B4HI95_DROSE 0.89 0.97 1 117 171 287 117 0 0 503 B4HI95 GM25537 (Fragment) OS=Drosophila sechellia GN=Dsec\GM25537 PE=4 SV=1
5 : E5KZA3_DROSI 0.89 0.98 1 117 204 320 117 0 0 818 E5KZA3 AGO2 (Fragment) OS=Drosophila simulans PE=4 SV=1
6 : B4QL34_DROSI 0.88 0.98 1 117 485 601 117 0 0 759 B4QL34 AGO2 OS=Drosophila simulans GN=AGO2 PE=4 SV=1
7 : E5KZ98_DROSI 0.88 0.98 1 117 204 320 117 0 0 818 E5KZ98 AGO2 (Fragment) OS=Drosophila simulans PE=4 SV=1
8 : Q2Q3W2_DROSI 0.88 0.98 1 117 226 342 117 0 0 840 Q2Q3W2 Argonaute-2 (Fragment) OS=Drosophila simulans GN=AGO2 PE=4 SV=1
9 : Q2Q3W7_DROSI 0.88 0.98 1 117 226 342 117 0 0 840 Q2Q3W7 Argonaute-2 (Fragment) OS=Drosophila simulans GN=AGO2 PE=4 SV=1
10 : Q2Q3W9_DROSI 0.88 0.98 1 117 226 342 117 0 0 840 Q2Q3W9 Argonaute-2 (Fragment) OS=Drosophila simulans GN=AGO2 PE=4 SV=1
11 : Q2Q3X1_DROTE 0.83 0.96 1 117 142 258 117 0 0 754 Q2Q3X1 Argonaute-2 (Fragment) OS=Drosophila teissieri GN=AGO2 PE=4 SV=1
12 : B3NI38_DROER 0.82 0.92 1 117 556 672 117 0 0 1168 B3NI38 GG15907 (Fragment) OS=Drosophila erecta GN=Dere\GG15907 PE=4 SV=1
13 : Q2Q3X0_DROSN 0.82 0.92 1 117 224 340 117 0 0 836 Q2Q3X0 Argonaute-2 (Fragment) OS=Drosophila santomea GN=AGO2 PE=4 SV=1
14 : Q2Q3X2_DROYA 0.82 0.93 1 117 224 340 117 0 0 836 Q2Q3X2 Argonaute-2 (Fragment) OS=Drosophila yakuba GN=AGO2 PE=4 SV=1
15 : B4PCH3_DROYA 0.81 0.92 1 117 561 677 117 0 0 1173 B4PCH3 AGO2 OS=Drosophila yakuba GN=AGO2 PE=4 SV=1
16 : E5KZ91_DROYA 0.81 0.92 1 117 204 320 117 0 0 816 E5KZ91 AGO2 (Fragment) OS=Drosophila yakuba PE=4 SV=1
17 : Q2Q3X4_DROYA 0.81 0.92 1 117 224 340 117 0 0 836 Q2Q3X4 Argonaute-2 (Fragment) OS=Drosophila yakuba GN=AGO2 PE=4 SV=1
18 : Q2Q3X7_DROYA 0.81 0.92 1 117 224 340 117 0 0 836 Q2Q3X7 Argonaute-2 (Fragment) OS=Drosophila yakuba GN=AGO2 PE=4 SV=1
19 : Q2Q3X8_DROYA 0.81 0.92 1 117 224 340 117 0 0 836 Q2Q3X8 Argonaute-2 (Fragment) OS=Drosophila yakuba GN=AGO2 PE=4 SV=1
20 : Q2Q3X6_DROYA 0.80 0.92 1 117 224 340 117 0 0 836 Q2Q3X6 Argonaute-2 (Fragment) OS=Drosophila yakuba GN=AGO2 PE=4 SV=1
21 : B3M505_DROAN 0.62 0.85 1 116 408 523 116 0 0 1019 B3M505 GF10056 OS=Drosophila ananassae GN=Dana\GF10056 PE=4 SV=1
22 : B4GDQ6_DROPE 0.62 0.82 22 117 406 501 96 0 0 990 B4GDQ6 GL22319 OS=Drosophila persimilis GN=Dper\GL22319 PE=4 SV=1
23 : B4GDQ8_DROPE 0.62 0.81 22 117 414 509 96 0 0 998 B4GDQ8 GL21510 OS=Drosophila persimilis GN=Dper\GL21510 PE=4 SV=1
24 : B5DYR9_DROPS 0.62 0.81 22 117 396 491 96 0 0 980 B5DYR9 GA27454 OS=Drosophila pseudoobscura pseudoobscura GN=Dpse\GA27454 PE=4 SV=1
25 : B4GUA7_DROPE 0.61 0.82 23 117 371 465 95 0 0 953 B4GUA7 GL24877 OS=Drosophila persimilis GN=Dper\GL24877 PE=4 SV=1
26 : B4GFG0_DROPE 0.59 0.81 21 117 193 289 97 0 0 778 B4GFG0 GL22202 OS=Drosophila persimilis GN=Dper\GL22202 PE=4 SV=1
27 : B5DQH3_DROPS 0.59 0.82 1 117 197 312 117 1 1 800 B5DQH3 GA23629 OS=Drosophila pseudoobscura pseudoobscura GN=Dpse\GA23629 PE=4 SV=1
28 : B4GTA5_DROPE 0.58 0.81 18 117 190 289 100 0 0 777 B4GTA5 GL14308 OS=Drosophila persimilis GN=Dper\GL14308 PE=4 SV=1
29 : B4GTA6_DROPE 0.58 0.81 18 117 190 289 100 0 0 766 B4GTA6 GL14309 OS=Drosophila persimilis GN=Dper\GL14309 PE=4 SV=1
30 : B4GTA7_DROPE 0.58 0.81 18 117 190 289 100 0 0 777 B4GTA7 GL14312 OS=Drosophila persimilis GN=Dper\GL14312 PE=4 SV=1
31 : B5DT30_DROPS 0.58 0.81 18 117 436 535 100 0 0 1023 B5DT30 GA28114 (Fragment) OS=Drosophila pseudoobscura pseudoobscura GN=Dpse\GA28114 PE=4 SV=1
32 : B5DY62_DROPS 0.58 0.81 22 117 388 483 96 0 0 972 B5DY62 GA27411 OS=Drosophila pseudoobscura pseudoobscura GN=Dpse\GA27411 PE=4 SV=1
33 : B4KUJ5_DROMO 0.57 0.81 1 117 437 552 117 1 1 1048 B4KUJ5 GI13119 OS=Drosophila mojavensis GN=Dmoj\GI13119 PE=4 SV=1
34 : B4G6N0_DROPE 0.56 0.79 1 117 240 356 117 0 0 845 B4G6N0 GL19556 OS=Drosophila persimilis GN=Dper\GL19556 PE=4 SV=1
35 : B5DIM7_DROPS 0.56 0.78 1 117 240 356 117 0 0 845 B5DIM7 GA26008 OS=Drosophila pseudoobscura pseudoobscura GN=Dpse\GA26008 PE=4 SV=1
36 : B5DU45_DROPS 0.56 0.79 1 117 114 229 117 1 1 593 B5DU45 GA27639 OS=Drosophila pseudoobscura pseudoobscura GN=Dpse\GA27639 PE=4 SV=1
37 : B4IWV1_DROGR 0.52 0.72 1 117 507 624 118 1 1 1115 B4IWV1 GH14741 OS=Drosophila grimshawi GN=Dgri\GH14741 PE=4 SV=1
38 : B4N082_DROWI 0.52 0.78 1 117 297 413 117 0 0 907 B4N082 GK24525 OS=Drosophila willistoni GN=Dwil\GK24525 PE=4 SV=1
39 : B4NLX0_DROWI 0.52 0.77 1 117 409 530 122 2 5 1012 B4NLX0 GK10600 OS=Drosophila willistoni GN=Dwil\GK10600 PE=4 SV=1
40 : W5ZRW2_BACDO 0.44 0.68 1 116 454 567 117 2 4 1057 W5ZRW2 Argonaute2 OS=Bactrocera dorsalis PE=2 SV=1
41 : M1EPM0_MUSPF 0.34 0.51 33 115 1 89 89 2 6 201 M1EPM0 Eukaryotic translation initiation factor 2C, 1 (Fragment) OS=Mustela putorius furo PE=2 SV=1
42 : B0WRW8_CULQU 0.32 0.64 2 115 362 467 115 4 10 974 B0WRW8 Putative uncharacterized protein OS=Culex quinquefasciatus GN=CpipJ_CPIJ009898 PE=4 SV=1
43 : G5A7K7_PHYSP 0.32 0.53 1 115 183 295 117 3 6 809 G5A7K7 Putative uncharacterized protein OS=Phytophthora sojae (strain P6497) GN=PHYSODRAFT_252786 PE=4 SV=1
44 : M4BSN4_HYAAE 0.32 0.52 1 115 174 286 117 3 6 803 M4BSN4 Uncharacterized protein OS=Hyaloperonospora arabidopsidis (strain Emoy2) PE=4 SV=1
45 : D6W6C8_TRICA 0.31 0.51 8 115 267 360 109 3 16 856 D6W6C8 Argonaute-2a OS=Tribolium castaneum GN=Ago2A PE=4 SV=1
46 : F0X160_9STRA 0.30 0.54 2 115 295 407 115 2 3 918 F0X160 Argonaute2 (AGO2) putative OS=Albugo laibachii Nc14 GN=AlNc14C559G12153 PE=4 SV=1
## ALIGNMENTS 1 - 46
SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
1 4 A A 0 0 98 33 32 SSSPPPPPPPAAAAAAAAAAA A AAAAAAAA AA
2 5 A M E -A 115 0A 55 35 21 MMMIIIIIIIMMMMMMMMMMM M MMMMMLLL LMM M
3 6 A P E > -A 114 0A 65 35 59 PPPPPPPPPPSSSSSSSSSSP T PPPSTPSN DSD S
4 7 A M H > S+ 0 0 2 35 35 MMMMMMMMMMMMMMMMMMMMV I MVVILVML VVV V
5 8 A I H > S+ 0 0 23 35 32 IIIIIIIIIIIIIIIIIIIIL I IVVIILLI VTT L
6 9 A E H > S+ 0 0 81 35 32 EEEQQQQQQQEEEEEEEEEEE E EEEDEEEE AES E
7 10 A Y H X>S+ 0 0 52 35 19 YYYYYYYYYYYYYYYYYYYYY Y YYYYYYYL SYY F
8 11 A L I X>S+ 0 0 0 36 6 LLLLLLLLLLLLLLLLLLLLL L LLLILILL LLLLL
9 12 A E I <>S+ 0 0 42 36 45 EEEEEEEEEEEEEEEEEEEEE E EEEEEEEN NCSTV
10 13 A R I <5S+ 0 0 143 34 76 RRREEEEEEERRXRLLLXLLR Q RRRQERNV REEDE
11 14 A F I <5S+ 0 0 92 36 46 FFFFFFFFFFYYYYYYYYYYF Y FFFYYYYL NTTFT
12 15 A S I < + 0 0 110 44 52 NNNNNNNNNNNDNNNNNNNNSNNN NNNNNNNMNNNINNL LPP.P
23 26 A L H > + 0 0 0 45 43 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLQLLE ATT.K
24 27 A D H > S+ 0 0 25 45 57 DDDDEEEEEEQDQQQQQQQQDDDDDDDDDDDDGEEDFDQP GST.T
25 28 A Y H > S+ 0 0 151 45 85 YYYYYYYYYYNSNNNNNNNNQYYYDYDYYYYYNSSYNRQR WLL.L
26 29 A S H X S+ 0 0 15 45 72 SSSSSSSSSSSSSSSSSSSSSRRRRRRKKKKRTRRRSLSG LAA.S
27 30 A R H < S+ 0 0 0 45 42 RRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRYRRRQYRL AKK.K
28 31 A R H < S+ 0 0 133 45 84 RRRRRRRRRRRRRRRRRRRRRSSSYYYSSSSYQSSSRPTQ QYH.A
29 32 A F H < S+ 0 0 127 46 108 FFFFFFFFFFFFFFFFFFFFFDDDKDKDDDDDLDDDKTYS QQQAQ
30 33 A L S X S+ 0 0 6 46 47 LLLLLLLLLLLLLLLLLLLLIIIIIIIIIIIIMIIIIIIL VHHLA
31 34 A E H > S+ 0 0 65 45 36 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE.DDEIEES HSAES
32 35 A P H 4 S+ 0 0 84 46 69 PPPPPPPPPPPPPPPPPPPPPSSSSSSSSSSSNAASQDQA DSAKI
33 36 A F H 4 S+ 0 0 120 47 16 FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFHHFFFFHFYFFFF
34 37 A L H >< S+ 0 0 1 47 34 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLILLLLLILTLSSLS
35 38 A R T 3< S+ 0 0 110 47 46 RRRKRRRRRRKKRRRRRRRRKSSNKKKTTTTKKKKNKKKRKKKKKK
36 39 A G T 3 S+ 0 0 35 47 29 GGGGGGGGGGGGGGGGGGGGGDDDGGGGGGGGGGGDGGGAEGAAQS
37 40 A I E < -B 56 0A 35 47 27 IIIIIIIIIIIIIIIIIIIIIIIIMMMMMMMMIIIIIIILIMIMLV
38 41 A N E -B 55 0A 83 47 44 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNFNKKERRKK
39 42 A V E -BC 54 115A 0 47 35 VVVVVVVVVVVVVVVVVVVVIIIIIIIIIIIIIVVIVVIVGVGGVG
40 43 A V E -BC 53 114A 20 47 27 VVVVVVVVVVVVVVVVVVVVVIIIVIVIIIIIVAAIVIIILVVVTV
41 44 A Y E -BC 52 113A 17 47 35 YYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYKYKKYK
42 45 A T - 0 0 63 47 69 TTTTTTTTTTTTTTTTTTTTTDDDDDDEEEEDEEEDEEESVTVVEV
43 46 A P - 0 0 19 47 37 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPAPPPPPPPEGNNIS
44 47 A P > - 0 0 16 46 25 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPV.IVPV
45 48 A Q T 3 S+ 0 0 185 46 77 QQQKKKKKKKQQQQQQQQQQTAAAAAAAAAAAAKKAKSAPT.TTGT
46 49 A S T 3 S+ 0 0 46 46 56 SSSSSSSSSSSSSSSSSSSSSCCCCCCCCCCCSSSCSCSSH.HHQH
47 50 A F S < S- 0 0 42 47 51 FFFFFFFFFFFFFFFFFFFFFFFFFLFLLLLLFFFFFFFFCPRRSR
48 51 A Q + 0 0 179 47 67 QQQQQQQQQQAAAAAAAAAAGGGGAAAGGGGAALLGGNNGGNPPGG
49 52 A S - 0 0 71 47 36 SSSSSSSSSSSSSSSSSSSSTSSSSSSSSSSSTSSSNSSAQGGGSD
50 53 A A - 0 0 75 46 30 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAMVVV.L
51 54 A P - 0 0 85 47 41 PPPPPPPPPPPPPPPPPPPPSPPPPPPPPPPPPTTPPPPPKGRKRK
52 55 A R E -B 41 0A 163 47 3 RRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRKRRRR
53 56 A V E -B 40 0A 87 47 42 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVTVISKTSSIT
54 57 A Y E -B 39 0A 64 47 3 YYYYYYYYYYYYYYYYYYYYYFFFFFFFFFFFYYYFFFFYYFYYFF
55 58 A R E -B 38 0A 137 47 23 RRRRRRRRRRKKKKKKKKKKKRRRRRRRRRRRKKKRRKKKRKRRRR
56 59 A V E +BD 37 99A 0 47 7 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVYVVVV
57 60 A N E - 0 0A 88 47 7 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCNNNNN
58 61 A G E - D 0 98A 0 46 14 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAAGGGGEN.GGGG
59 62 A L E - D 0 97A 9 47 16 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLILLVVSLLLL
60 63 A S E - 0 0A 7 47 41 SSSSSSSSSSSSSSSSSSSSSSSSSTSCCCCTSTTSSTSSTLSSRS
61 64 A R E S+ 0 0A 233 47 63 RRRRRRRRRRSRSSSSSSSSAKKKKKKKKKKKPQQKQSPRRKKRAK
62 65 A A E S- 0 0A 16 47 87 AAAAAAAAAAGCGGGGGGGGYAAAFFFVVVVFQYYANSQERGDDPT
63 66 A P E >> - D 0 95A 30 47 23 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPSSSPPSAPS
64 67 A A T 34 S+ 0 0 0 47 7 AAAAAAAAAAAAAAAAAAAASAAAAAAAAAAAAAAAAAAAAAAASA
65 68 A S T 34 S+ 0 0 46 47 53 SSSNNNNNNNSSSSSSSSSNNSSSSSSSSSSSNSSSRRDSSSEDQQ
66 69 A S T <4 S+ 0 0 82 47 70 SSSSSSSSSSSKSSSSSSSSKTTTSSSTTTTSERRTSYQSHTNRAD
67 70 A E < - 0 0 38 47 59 EEEEEEEEEEEEEEEEEEEEQQQQQLQQQQQLQQQQEQQLQQTTRL
68 71 A T E -F 77 0B 66 47 79 TTTIVVVVVVTITTTTTTTTTTTTKKKTTTTKKAATKQKSTKFFFF
69 72 A F E -F 76 0B 43 47 7 FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFTF
70 73 A E E +F 75 0B 147 47 44 EEEEEEEEEEEEEEEEEEEEVEEEEEEEEEEEKNNEKQqkpkeeLd
71 74 A H S S- 0 0 107 47 99 HHHHHHHHHHNHSSSSSSSSLLLLLLLLLLLLLCCLCLedgeddGd
72 75 A D S S- 0 0 146 47 18 DDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDGDDTQDDDDS
73 76 A G S S+ 0 0 56 47 18 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGDGGGENKGTGGGGG
74 77 A K - 0 0 152 47 44 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKTTKVKKEVSQQKA
75 78 A K E +F 70 0B 150 47 63 KKKKKKKKKKKKKKKKKKKKTEEEQQQEEEEQTKKEVTEKEERRVK
76 79 A V E -F 69 0B 64 47 60 VVVVVVVVVVVVVVVVVVVVLTTTTTTMMMMTMVVTMLTLCSMLTV
77 80 A T E > -F 68 0B 36 47 15 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTSSTS
78 81 A I H > S+ 0 0 1 47 15 IIIIIIIIIIIIIIIIIIIIVVVVVVVVVVVVVVVVVVVVVVIIVV
79 82 A A H > S+ 0 0 15 47 32 AAAAAAAAAAAAAAAAAAAASAAAAAAAAAAASAAAEEKQAAVAEA
80 83 A S H > S+ 0 0 77 47 72 SSSSSSSSSSASAAAAAAAADKKKEDEEEEEDEAAKEQESQAQQKA
81 84 A Y H X S+ 0 0 59 47 0 YYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYY
82 85 A F H <>S+ 0 0 2 47 1 FFFFFFFFFFFFFFFFFFFFFFFFFFFYYYYFFFFFFFFFFFFFYF
83 86 A H H ><5S+ 0 0 120 47 64 HHHHHHHHHHQQQQQQQQQQKKKKRRRKKKKRRKKKKQRAKQQEQA
84 87 A S H 3<5S+ 0 0 90 47 37 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSGSQKRQEK
85 88 A R T 3<5S- 0 0 101 47 34 RRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRKQTTVN
86 89 A N T < 5S+ 0 0 128 47 73 NNNNNNNNNNNNNNNNNNNNNKKEKKKQQQQKNGGESNNGYGYYKY
87 90 A Y < - 0 0 63 47 51 YYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYHHYYYYYnVnkrG
88 91 A P - 0 0 80 47 79 PPPPPPPPPPNNNNNNNNNNVDDDNNNNNNNNNAADKSIKqRrrrC
89 92 A L - 0 0 16 47 0 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
90 93 A K S S+ 0 0 135 47 28 KKKKKKKKKKKKKKKKKKKKKKKKKMKKKKKMKRRRKRKKKRRRQR
91 94 A F S > S+ 0 0 8 47 3 FFFYYYYYYYFFFFFFFFFFYFFFYYYFFFFYYFFFYYYYYFYYYY
92 95 A P T 3 S+ 0 0 23 47 0 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP
93 96 A Q T 3 S+ 0 0 108 47 62 QQQQQQQQQQQQQQQQQQQQSNNNNNNNNNNNKNNNMNNHHDKKHG
94 97 A L S < S- 0 0 7 47 0 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
95 98 A H E -D 63 0A 10 47 83 HHHHHHHHHHHHHHHHHHHHQLLLLLLLLLLLHLLLQRHGPPPPPP
96 99 A C E - E 0 109A 0 47 11 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCVCCTC
97 100 A L E -DE 59 108A 0 47 3 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLVLMLLLL
98 101 A N E +DE 58 107A 26 47 49 NNNNNNNNNNHDHHHHHHHHHHHHHHHHHHHHHHHHSYHVQHHHWH
99 102 A V E +DE 56 106A 0 47 8 VVVVVVVVVVVAVVVVVVVVVVVVVVVVVVVVVVVVVVVAVVVVVV
100 103 A G E S- E 0 105A 44 47 0 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
101 104 A S - 0 0 46 47 52 SSSSSSSSSSPPPPPPPPPPPPPPPPPPPPPPPSSPHPPSQSAASA
102 105 A S S S+ 0 0 119 47 54 SSSSSSSSSSPPAPPPPPPPPPPPPPPPPPPPPPPPPLPSETPPRM
103 106 A I S S+ 0 0 165 47 81 IIIVVVVVVVMATTTTTTTTVLLLLLLLLLLLAQQLTDAVQIQQQQ
104 107 A K S S- 0 0 134 47 19 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKTMKNRKKKRKKRK
105 108 A S E -E 100 0A 44 47 75 SSSSSSSSSSHRHHHHHHHHNNHHNNNHHHHNNSSHVNQPHNKKEK
106 109 A I E -E 99 0A 47 47 44 IIIVVVVVVVIIIIIIIIIIIIIIIIIIIIIIIVVILIINTINNVN
107 110 A L E +E 98 0A 27 47 53 LLLMMMMMMMLLLLLLLLLLYYYYYYYYYYYYYYYYLFYYYMYYLY
108 111 A L E -E 97 0A 5 47 9 LLLLLLLLLLLLLLLLLLLLVLLLLLLLLLLLLLLLLLVLLVLLIL
109 112 A P E > -E 96 0A 1 47 0 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP
110 113 A I G > S+ 0 0 4 47 22 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIMIIILMMMLM
111 114 A E G 3 S+ 0 0 19 47 0 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE
112 115 A L G < S+ 0 0 1 47 13 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLVLVVFV
113 116 A C E < - C 0 41A 2 47 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
114 117 A S E -AC 3 40A 5 47 79 SSSSSSSSSSTSATTTTTTTHRRRRRRRRRRRRRRRRRRSNAHHTH
115 118 A I E -AC 2 39A 38 47 1 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIVI
116 119 A E 0 0 135 41 6 EEEEEEEEEEEEEEEEEEEEEDDDEEEEEEEEEEEDEEEE
117 120 A E 0 0 186 39 19 EEEEEEEEEEEEEEEEEEEE DDDDDDDDDDDEEEDEDE
## SEQUENCE PROFILE AND ENTROPY
SeqNo PDBNo V L I M F W Y G A P S T C H R K Q E N D NOCC NDEL NINS ENTROPY RELENT WEIGHT
1 4 A 0 0 0 0 0 0 0 0 70 21 9 0 0 0 0 0 0 0 0 0 33 0 0 0.799 26 0.68
2 5 A 0 11 20 69 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 35 0 0 0.828 27 0.79
3 6 A 0 0 0 0 0 0 0 0 0 46 40 6 0 0 0 0 0 0 3 6 35 0 0 1.153 38 0.41
4 7 A 23 6 6 66 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 35 0 0 0.940 31 0.64
5 8 A 9 11 74 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 35 0 0 0.843 28 0.67
6 9 A 0 0 0 0 0 0 0 0 3 0 3 0 0 0 0 0 20 71 0 3 35 0 0 0.867 28 0.67
7 10 A 0 3 0 0 3 0 91 0 0 0 3 0 0 0 0 0 0 0 0 0 35 0 0 0.387 12 0.81
8 11 A 0 94 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 0.215 7 0.94
9 12 A 3 0 0 0 0 0 0 0 0 0 3 3 3 0 0 0 0 83 6 0 36 0 0 0.711 23 0.54
10 13 A 3 15 0 0 0 0 0 0 0 0 0 0 0 0 38 0 6 32 3 3 34 0 0 1.492 49 0.23
11 14 A 0 3 0 0 44 0 42 0 0 0 0 8 0 0 0 0 0 0 3 0 36 0 0 1.131 37 0.54
12 15 A 6 6 0 0 0 0 0 36 3 0 33 0 0 0 3 0 14 0 0 0 36 0 0 1.528 51 0.19
13 16 A 0 56 22 3 0 0 0 0 3 0 3 3 0 0 6 0 3 0 0 3 36 0 0 1.419 47 0.33
14 17 A 0 6 0 3 0 0 0 0 0 3 0 0 0 3 3 56 6 0 19 3 36 7 2 1.464 48 0.33
15 18 A 0 0 0 0 0 0 0 17 55 3 10 3 0 0 0 3 3 3 0 0 29 0 0 1.446 48 0.36
16 19 A 0 3 3 0 0 0 0 0 0 0 3 0 0 0 10 80 0 0 0 0 30 0 0 0.749 24 0.59
17 20 A 0 0 90 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 3 31 1 0 0.380 12 0.64
18 21 A 0 0 0 0 0 0 0 0 0 3 3 9 0 0 0 3 0 6 63 14 35 0 0 1.249 41 0.44
19 22 A 0 0 0 0 0 0 0 3 8 3 0 3 0 0 8 16 0 0 61 0 38 0 0 1.283 42 0.34
20 23 A 0 0 0 0 0 0 0 0 0 0 18 46 0 0 3 0 33 0 0 0 39 0 0 1.125 37 0.29
21 24 A 0 5 0 3 0 0 0 0 0 0 5 88 0 0 0 0 0 0 0 0 40 0 0 0.509 16 0.66
22 25 A 0 5 2 2 0 0 0 0 0 7 2 0 0 0 0 0 0 0 80 2 44 0 0 0.850 28 0.47
23 26 A 0 87 0 0 0 0 0 0 2 0 0 4 0 0 0 2 2 2 0 0 45 0 0 0.601 20 0.57
24 27 A 0 0 0 0 2 0 0 4 0 2 2 4 0 0 0 0 22 18 0 44 45 0 0 1.532 51 0.42
25 28 A 0 7 0 0 0 2 47 0 0 0 7 0 0 0 4 0 4 0 24 4 45 0 0 1.561 52 0.14
26 29 A 0 4 0 0 0 0 0 2 4 0 56 2 0 0 22 9 0 0 0 0 45 0 0 1.322 44 0.28
27 30 A 0 2 0 0 0 0 4 0 2 0 0 0 0 0 82 7 2 0 0 0 45 0 0 0.734 24 0.57
28 31 A 0 0 0 0 0 0 11 0 2 2 22 2 0 2 51 0 7 0 0 0 45 0 0 1.440 48 0.15
29 32 A 0 2 0 0 48 0 2 0 2 0 2 2 0 0 0 7 9 0 0 26 46 0 0 1.510 50 -0.08
30 33 A 2 50 39 2 0 0 0 0 2 0 0 0 0 4 0 0 0 0 0 0 46 1 0 1.100 36 0.53
31 34 A 0 0 2 0 0 0 0 0 2 0 7 0 0 2 0 0 0 82 0 4 45 0 0 0.734 24 0.64
32 35 A 0 0 2 0 0 0 0 0 9 48 28 0 0 0 0 2 4 0 2 4 46 0 0 1.445 48 0.31
33 36 A 0 0 0 0 91 0 2 0 0 0 0 0 0 6 0 0 0 0 0 0 47 0 0 0.339 11 0.84
34 37 A 0 87 4 0 0 0 0 0 0 0 6 2 0 0 0 0 0 0 0 0 47 0 0 0.511 17 0.66
35 38 A 0 0 0 0 0 0 0 0 0 0 4 9 0 0 40 43 0 0 4 0 47 0 0 1.208 40 0.53
36 39 A 0 0 0 0 0 0 0 79 6 0 2 0 0 0 0 0 2 2 0 9 47 0 0 0.819 27 0.70
37 40 A 2 4 72 21 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0.780 26 0.72
38 41 A 0 0 0 0 2 0 0 0 0 0 4 0 0 0 4 9 0 2 79 0 47 0 0 0.831 27 0.55
39 42 A 60 0 32 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0.883 29 0.64
40 43 A 64 2 28 0 0 0 0 0 4 0 0 2 0 0 0 0 0 0 0 0 47 0 0 0.940 31 0.72
41 44 A 0 0 0 0 0 0 91 0 0 0 0 0 0 0 0 9 0 0 0 0 47 0 0 0.291 9 0.65
42 45 A 9 0 0 0 0 0 0 0 0 0 2 49 0 0 0 0 0 23 0 17 47 0 0 1.283 42 0.31
43 46 A 0 0 2 0 0 0 0 2 2 85 2 0 0 0 0 0 0 2 4 0 47 1 0 0.681 22 0.63
44 47 A 7 0 2 0 0 0 0 0 0 91 0 0 0 0 0 0 0 0 0 0 46 0 0 0.344 11 0.74
45 48 A 0 0 0 0 0 0 0 2 30 2 2 11 0 0 0 22 30 0 0 0 46 0 0 1.547 51 0.22
46 49 A 0 0 0 0 0 0 0 0 0 0 61 0 28 9 0 0 2 0 0 0 46 0 0 0.955 31 0.44
47 50 A 0 13 0 0 74 0 0 0 0 2 2 0 2 0 6 0 0 0 0 0 47 0 0 0.904 30 0.49
48 51 A 0 4 0 0 0 0 0 30 32 4 0 0 0 0 0 0 23 0 6 0 47 0 0 1.509 50 0.33
49 52 A 0 0 0 0 0 0 0 6 2 0 81 4 0 0 0 0 2 0 2 2 47 1 0 0.810 27 0.63
50 53 A 7 2 0 2 0 0 0 0 89 0 0 0 0 0 0 0 0 0 0 0 46 0 0 0.447 14 0.70
51 54 A 0 0 0 0 0 0 0 2 0 81 2 4 0 0 4 6 0 0 0 0 47 0 0 0.780 26 0.59
52 55 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 98 2 0 0 0 0 47 0 0 0.103 3 0.97
53 56 A 81 0 4 0 0 0 0 0 0 0 6 6 0 0 0 2 0 0 0 0 47 0 0 0.739 24 0.57
54 57 A 0 0 0 0 38 0 62 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0.666 22 0.96
55 58 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 62 38 0 0 0 0 47 0 0 0.666 22 0.76
56 59 A 98 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0.103 3 0.93
57 60 A 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 98 0 47 1 0 0.103 3 0.92
58 61 A 0 0 0 0 0 0 0 91 4 0 0 0 0 0 0 0 0 2 2 0 46 0 0 0.386 12 0.86
59 62 A 4 91 2 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 47 0 0 0.380 12 0.84
60 63 A 0 2 0 0 0 0 0 0 0 0 74 13 9 0 2 0 0 0 0 0 47 0 0 0.856 28 0.59
61 64 A 0 0 0 0 0 0 0 0 4 4 21 0 0 0 32 32 6 0 0 0 47 0 0 1.503 50 0.36
62 65 A 9 0 0 0 9 0 6 21 32 2 2 2 2 0 2 0 4 2 2 4 47 0 0 2.131 71 0.13
63 66 A 0 0 0 0 0 0 0 0 2 87 11 0 0 0 0 0 0 0 0 0 47 0 0 0.439 14 0.77
64 67 A 0 0 0 0 0 0 0 0 96 0 4 0 0 0 0 0 0 0 0 0 47 0 0 0.176 5 0.92
65 68 A 0 0 0 0 0 0 0 0 0 0 64 0 0 0 4 0 4 2 21 4 47 0 0 1.101 36 0.46
66 69 A 0 0 0 0 0 0 2 0 2 0 55 19 0 2 6 4 2 2 2 2 47 0 0 1.527 50 0.30
67 70 A 0 9 0 0 0 0 0 0 0 0 0 4 0 0 2 0 38 47 0 0 47 0 0 1.149 38 0.40
68 71 A 13 0 4 0 9 0 0 0 4 0 2 49 0 0 0 17 2 0 0 0 47 0 0 1.556 51 0.20
69 72 A 0 0 0 0 98 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 47 0 0 0.103 3 0.92
70 73 A 2 2 0 0 0 0 0 0 0 2 0 0 0 0 0 9 4 74 4 2 47 0 7 1.026 34 0.55
71 74 A 0 32 0 0 0 0 0 4 0 0 17 0 6 26 0 0 0 4 2 9 47 0 0 1.750 58 0.01
72 75 A 0 0 0 0 0 0 0 2 0 0 2 2 0 0 0 0 2 2 0 89 47 0 0 0.510 17 0.82
73 76 A 0 0 0 0 0 0 0 89 0 0 0 2 0 0 0 2 0 2 2 2 47 0 0 0.510 17 0.81
74 77 A 4 0 0 0 0 0 0 0 2 0 2 4 0 0 0 81 4 2 0 0 47 0 0 0.821 27 0.56
75 78 A 4 0 0 0 0 0 0 0 0 0 0 6 0 0 4 53 9 23 0 0 47 0 0 1.330 44 0.36
76 79 A 51 9 0 15 0 0 0 0 0 0 2 21 2 0 0 0 0 0 0 0 47 0 0 1.330 44 0.39
77 80 A 0 0 0 0 0 0 0 0 0 0 6 94 0 0 0 0 0 0 0 0 47 0 0 0.237 7 0.84
78 81 A 51 0 49 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0.693 23 0.84
79 82 A 2 0 0 0 0 0 0 0 83 0 4 0 0 0 0 2 2 6 0 0 47 0 0 0.711 23 0.67
80 83 A 0 0 0 0 0 0 0 0 28 0 28 0 0 0 0 11 9 19 0 6 47 0 0 1.651 55 0.28
81 84 A 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0.000 0 1.00
82 85 A 0 0 0 0 89 0 11 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0.339 11 0.99
83 86 A 0 0 0 0 0 0 0 0 4 0 0 0 0 23 13 28 30 2 0 0 47 0 0 1.535 51 0.36
84 87 A 0 0 0 0 0 0 0 2 0 0 85 0 0 0 2 4 4 2 0 0 47 0 0 0.652 21 0.63
85 88 A 2 0 0 0 0 0 0 0 0 0 0 4 0 0 87 2 2 0 2 0 47 0 0 0.581 19 0.66
86 89 A 0 0 0 0 0 0 9 9 0 0 2 0 0 0 0 15 9 4 53 0 47 0 0 1.465 48 0.27
87 90 A 2 0 0 0 0 0 83 2 0 0 0 0 0 4 2 2 0 0 4 0 47 0 4 0.751 25 0.48
88 91 A 2 0 2 0 0 0 0 0 4 23 2 0 2 0 9 4 2 0 40 9 47 0 0 1.804 60 0.20
89 92 A 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0.000 0 1.00
90 93 A 0 0 0 4 0 0 0 0 0 0 0 0 0 0 17 77 2 0 0 0 47 0 0 0.722 24 0.72
91 94 A 0 0 0 0 53 0 47 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0.691 23 0.96
92 95 A 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 47 0 0 0.000 0 1.00
93 96 A 0 0 0 2 0 0 0 2 0 0 2 0 0 6 0 6 45 0 34 2 47 0 0 1.406 46 0.37
94 97 A 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0.000 0 1.00
95 98 A 0 30 0 0 0 0 0 2 0 13 0 0 0 49 2 0 4 0 0 0 47 0 0 1.271 42 0.16
96 99 A 2 0 0 0 0 0 0 0 0 0 0 2 96 0 0 0 0 0 0 0 47 0 0 0.205 6 0.89
97 100 A 2 96 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0.205 6 0.96
98 101 A 2 0 0 0 0 2 2 0 0 0 2 0 0 64 0 0 2 0 23 2 47 0 0 1.118 37 0.50
99 102 A 96 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0.176 5 0.92
100 103 A 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0.000 0 1.00
101 104 A 0 0 0 0 0 0 0 0 6 55 34 0 0 2 0 0 2 0 0 0 47 0 0 1.034 34 0.48
102 105 A 0 2 0 2 0 0 0 0 2 62 26 2 0 0 2 0 0 2 0 0 47 0 0 1.138 37 0.45
103 106 A 19 26 11 2 0 0 0 0 6 0 0 19 0 0 0 0 15 0 0 2 47 0 0 1.843 61 0.19
104 107 A 0 0 0 2 0 0 0 0 0 0 0 2 0 0 6 87 0 0 2 0 47 0 0 0.541 18 0.80
105 108 A 2 0 0 0 0 0 0 0 0 2 28 0 0 36 2 6 2 2 19 0 47 0 0 1.625 54 0.25
106 109 A 21 2 66 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 9 0 47 0 0 0.977 32 0.56
107 110 A 0 34 0 17 2 0 47 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 1.105 36 0.47
108 111 A 6 91 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0.339 11 0.90
109 112 A 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 47 0 0 0.000 0 1.00
110 113 A 0 4 85 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0.510 17 0.78
111 114 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 47 0 0 0.000 0 1.00
112 115 A 9 89 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0.392 13 0.87
113 116 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 47 0 0 0.000 0 1.00
114 117 A 0 0 0 0 0 0 0 0 4 0 28 19 0 9 38 0 0 0 2 0 47 0 0 1.466 48 0.21
115 118 A 2 0 98 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0.103 3 0.98
116 119 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 90 0 10 41 0 0 0.320 10 0.94
117 120 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67 0 33 39 0 0 0.637 21 0.80
## INSERTION LIST
AliNo IPOS JPOS Len Sequence
37 15 521 1 mEp
39 15 423 4 nSRYAt
39 71 483 1 qLe
40 68 521 1 kId
41 39 39 5 pLQLESg
41 56 61 1 nLq
42 61 422 1 kLe
43 67 249 1 eNd
43 84 267 1 nIr
44 67 240 1 eTd
44 84 258 1 kLr
45 66 332 1 rCr
46 68 362 1 dDd
//