Complet list of 1txm hssp file
Complete list of 1txm.hssp file
HSSP HOMOLOGY DERIVED SECONDARY STRUCTURE OF PROTEINS , VERSION 2.0 2011
PDBID 1TXM
THRESHOLD according to: t(L)=(290.15 * L ** -0.562) + 5
REFERENCE Sander C., Schneider R. : Database of homology-derived protein structures. Proteins, 9:56-68 (1991).
CONTACT Maintained at http://www.cmbi.ru.nl/ by Maarten L. Hekkelman
DATE file generated on 2014-05-10
HEADER NEUROTOXIN 19-NOV-96 1TXM
COMPND MOL_ID: 1; MOLECULE: MAUROTOXIN; CHAIN: A; ENGINEERED: YES
SOURCE MOL_ID: 1; ORGANISM_SCIENTIFIC: SCORPIO MAURUS; ORGANISM_TAXID: 53956;
AUTHOR E.BLANC,J.-M.SABATIER,R.KHARRAT,S.MEUNIER,M.EL AYEB,J.VAN RIETSCHOTEN,
DBREF 1TXM A 1 34 UNP P80719 SCXM_SCOMA 1 34
SEQLENGTH 34
NCHAIN 1 chain(s) in 1TXM data set
NALIGN 39
NOTATION : ID: EMBL/SWISSPROT identifier of the aligned (homologous) protein
NOTATION : STRID: if the 3-D structure of the aligned protein is known, then STRID is the Protein Data Bank identifier as taken
NOTATION : from the database reference or DR-line of the EMBL/SWISSPROT entry
NOTATION : %IDE: percentage of residue identity of the alignment
NOTATION : %SIM (%WSIM): (weighted) similarity of the alignment
NOTATION : IFIR/ILAS: first and last residue of the alignment in the test sequence
NOTATION : JFIR/JLAS: first and last residue of the alignment in the alignend protein
NOTATION : LALI: length of the alignment excluding insertions and deletions
NOTATION : NGAP: number of insertions and deletions in the alignment
NOTATION : LGAP: total length of all insertions and deletions
NOTATION : LSEQ2: length of the entire sequence of the aligned protein
NOTATION : ACCNUM: SwissProt accession number
NOTATION : PROTEIN: one-line description of aligned protein
NOTATION : SeqNo,PDBNo,AA,STRUCTURE,BP1,BP2,ACC: sequential and PDB residue numbers, amino acid (lower case = Cys), secondary
NOTATION : structure, bridge partners, solvent exposure as in DSSP (Kabsch and Sander, Biopolymers 22, 2577-2637(1983)
NOTATION : VAR: sequence variability on a scale of 0-100 as derived from the NALIGN alignments
NOTATION : pair of lower case characters (AvaK) in the alignend sequence bracket a point of insertion in this sequence
NOTATION : dots (....) in the alignend sequence indicate points of deletion in this sequence
NOTATION : SEQUENCE PROFILE: relative frequency of an amino acid type at each position. Asx and Glx are in their
NOTATION : acid/amide form in proportion to their database frequencies
NOTATION : NOCC: number of aligned sequences spanning this position (including the test sequence)
NOTATION : NDEL: number of sequences with a deletion in the test protein at this position
NOTATION : NINS: number of sequences with an insertion in the test protein at this position
NOTATION : ENTROPY: entropy measure of sequence variability at this position
NOTATION : RELENT: relative entropy, i.e. entropy normalized to the range 0-100
NOTATION : WEIGHT: conservation weight
## PROTEINS : identifier and alignment statistics
NR. ID STRID %IDE %WSIM IFIR ILAS JFIR JLAS LALI NGAP LGAP LSEQ2 ACCNUM PROTEIN
1 : KAX62_SCOMA 1WPD 1.00 1.00 1 34 1 34 34 0 0 34 P80719 Potassium channel toxin alpha-KTx 6.2 OS=Scorpio maurus palmatus PE=1 SV=1
2 : KAX6D_HETSP 1V56 0.82 0.94 1 34 1 34 34 0 0 34 P84094 Potassium channel toxin alpha-KTx 6.13 OS=Heterometrus spinifer PE=1 SV=1
3 : I6NWV2_HETLA 0.79 0.97 1 34 27 60 34 0 0 61 I6NWV2 Kv1.3 potassium channel blocker (Precursor) OS=Heterometrus laoticus GN=Tx3 PE=3 SV=1
4 : KAX64_PANIM 1N8M 0.76 0.91 1 34 4 37 34 0 0 38 P58498 Potassium channel toxin alpha-KTx 6.4 OS=Pandinus imperator PE=1 SV=1
5 : KAX65_PANIM 1QKY 0.74 0.85 1 34 4 37 34 0 0 38 P58490 Potassium channel toxin alpha-KTx 6.5 OS=Pandinus imperator PE=1 SV=1
6 : KAX6F_HEMLE 0.74 0.91 1 34 1 34 34 0 0 35 P85528 Potassium channel toxin alpha-KTx 6.15 OS=Hemiscorpius lepturus PE=1 SV=1
7 : KAX61_PANIM 1WZ5 0.68 0.82 1 34 2 35 34 0 0 35 Q10726 Potassium channel toxin alpha-KTx 6.1 OS=Pandinus imperator PE=1 SV=1
8 : KAX69_OPICA 0.68 0.91 1 34 27 60 34 0 0 61 Q6XLL6 Potassium channel toxin alpha-KTx 6.9 OS=Opistophthalmus carinatus PE=2 SV=1
9 : KAX6A_OPICA 0.68 0.91 1 34 26 59 34 0 0 60 Q6XLL5 Potassium channel toxin alpha-KTx 6.10 OS=Opistophthalmus carinatus PE=2 SV=1
10 : KAX68_OPICA 0.62 0.79 1 34 27 60 34 0 0 61 Q6XLL7 Potassium channel toxin alpha-KTx 6.8 OS=Opistophthalmus carinatus PE=2 SV=1
11 : KAX6H_OPICY 0.62 0.82 1 34 1 34 34 0 0 34 P86116 Potassium channel toxin alpha-KTx 6.17 OS=Opisthacanthus cayaporum PE=1 SV=2
12 : I6NXS5_HETLA 0.61 0.79 2 34 2 34 33 0 0 35 I6NXS5 Kv1.3 potassium channel blocker (Fragment) OS=Heterometrus laoticus GN=Tx2 PE=2 SV=1
13 : KAX63_HETSP 1WPD 0.61 0.76 2 34 2 34 33 0 0 34 P59867 Potassium channel toxin alpha-KTx 6.3 OS=Heterometrus spinifer PE=1 SV=1
14 : KAX71_PANIM 2PTA 0.61 0.88 1 33 14 46 33 0 0 47 P55927 Potassium channel toxin alpha-KTx 7.1 (Fragment) OS=Pandinus imperator GN=PTX-1 PE=1 SV=2
15 : KAX72_PANIM 1C49 0.61 0.85 1 33 2 34 33 0 0 35 P55928 Potassium channel toxin alpha-KTx 7.2 OS=Pandinus imperator PE=1 SV=1
16 : KAXO1_OPICY 0.58 0.85 1 26 1 26 26 0 0 26 P86115 Toxin OcyKTx1 (Fragment) OS=Opisthacanthus cayaporum PE=1 SV=1
17 : KAX66_OPICA 0.56 0.82 1 34 27 60 34 0 0 61 Q6XLL9 Potassium channel toxin alpha-KTx 6.6 OS=Opistophthalmus carinatus PE=2 SV=1
18 : KAX67_OPICA 0.56 0.79 1 34 27 60 34 0 0 61 Q6XLL8 Potassium channel toxin alpha-KTx 6.7 OS=Opistophthalmus carinatus PE=2 SV=1
19 : KAX19_CENLM 0.55 0.74 1 31 5 35 31 0 0 36 P59848 Potassium channel toxin alpha-KTx 1.9 (Fragment) OS=Centruroides limbatus PE=1 SV=1
20 : H2CYS1_PANCV 0.53 0.66 2 33 30 61 32 0 0 63 H2CYS1 Alpha-KTx-like peptide OS=Pandinus cavimanus PE=3 SV=1
21 : KA232_VAEMS 0.53 0.75 1 32 4 34 32 1 1 35 P0DJ32 Potassium channel toxin alpha-KTx 23.2 OS=Vaejovis mexicanus smithi PE=1 SV=1
22 : KAX1B_CENNO 0.53 0.66 1 32 5 36 32 0 0 37 P0C182 Potassium channel toxin alpha-KTx 1.11 OS=Centruroides noxius PE=1 SV=1
23 : KAX_ISOMC 0.53 0.67 3 32 30 59 30 0 0 60 P0CJ24 Potassium channel toxin ImKTx88 OS=Isometrus maculatus PE=2 SV=1
24 : A0RZD1_MESMA 0.52 0.76 1 33 25 57 33 0 0 57 A0RZD1 Potassium-channel toxin protein OS=Mesobuthus martensii GN=TX1 PE=3 SV=1
25 : KAX15_MESMA 1BIG 0.52 0.76 1 33 25 57 33 0 0 57 Q9NII6 Potassium channel toxin alpha-KTx 1.5 OS=Mesobuthus martensii PE=1 SV=1
26 : KA166_BUTOS 0.50 0.75 1 32 27 58 32 0 0 58 B8XH42 Potassium channel toxin alpha-KTx 16.6 OS=Buthus occitanus israelis PE=2 SV=1
27 : KA231_VAEMS 2K9O 0.50 0.71 1 34 4 36 34 1 1 36 P0DJ31 Potassium channel toxin alpha-KTx 23.1 OS=Vaejovis mexicanus smithi PE=1 SV=1
28 : KAX14_CENLM 0.50 0.69 1 32 5 36 32 0 0 37 P0C167 Potassium channel toxin alpha-KTx 1.4 OS=Centruroides limbatus PE=1 SV=1
29 : KAX1A_PARTR 0.50 0.75 1 32 4 35 32 0 0 37 P83112 Potassium channel toxin alpha-KTx 1.10 OS=Parabuthus transvaalicus PE=1 SV=1
30 : KAX43_TITDI 0.50 0.72 1 32 5 36 32 0 0 37 P59925 Potassium channel toxin alpha-KTx 4.3 OS=Tityus discrepans PE=1 SV=1
31 : KAX6B_OPIMA 1WMT 0.49 0.71 1 34 26 60 35 1 1 63 P0C194 Potassium channel toxin alpha-KTx 6.11 OS=Opisthacanthus madagascariensis PE=1 SV=1
32 : KAX1D_LEIQH 0.48 0.70 1 33 5 37 33 0 0 37 P59944 Potassium channel toxin alpha-KTx 1.13 OS=Leiurus quinquestriatus hebraeus PE=1 SV=1
33 : KAX1F_MESMA 0.48 0.73 1 33 25 57 33 0 0 57 H2ER23 Potassium channel toxin alpha-KTx 1.15 OS=Mesobuthus martensii PE=2 SV=1
34 : KAX22_CENMA 1MTX 0.48 0.73 1 32 5 37 33 1 1 39 P40755 Potassium channel toxin alpha-KTx 2.2 OS=Centruroides margaritatus PE=1 SV=1
35 : KAX25_CENLM 1HLY 0.48 0.70 1 32 5 37 33 1 1 39 P59847 Potassium channel toxin alpha-KTx 2.5 OS=Centruroides limbatus PE=1 SV=1
36 : V9LLY8_MESMA 0.48 0.76 1 33 25 57 33 0 0 57 V9LLY8 Toxin BmTX4 OS=Mesobuthus martensii PE=3 SV=1
37 : KA125_LYCMC 0.47 0.69 1 32 28 59 32 0 0 60 P0CH12 Potassium channel toxin alpha-KTx 12.5 OS=Lychas mucronatus PE=2 SV=1
38 : KA165_LEIQH 0.47 0.72 1 32 5 36 32 0 0 36 P45660 Potassium channel toxin alpha-KTx 16.5 OS=Leiurus quinquestriatus hebraeus PE=1 SV=1
39 : KAX44_TITOB 0.47 0.69 1 32 5 36 32 0 0 37 P60210 Potassium channel toxin alpha-KTx 4.4 OS=Tityus obscurus PE=1 SV=1
## ALIGNMENTS 1 - 39
SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
1 1 A V 0 0 144 36 17 VIIIIIVIIII IIIIIV IV VVVIVMVIVVVVVIVV
2 2 A S - 0 0 79 39 55 SRSRRKKRRKRSSSSRKKKRSD KKRSSRKPSKKKKKRK
3 3 A a - 0 0 2 40 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
4 4 A T S S- 0 0 116 40 79 TSTGTTRSSRQRRTTQRRTGVTNTTYVSKTRTTTTTSYR
5 5 A G S > S- 0 0 28 40 56 GGGGGLGGGTGTTNNGTTTGGVGGGAGVSGGTASSASDG
6 6 A S H > S+ 0 0 33 40 41 SSSSTSTTSPSPPPESPPSSSSSSSSSSSSTSSPPSSSS
7 7 A K H > S+ 0 0 141 40 41 KRKRKKSRKKNKKKKNKKKSKKSKKRPKKKSKKKKKSRK
8 8 A D H >4 S+ 0 0 78 40 37 DDQDDDDEQDQDDQQQDDEEEEEQQEEEEQDEQQQQSQE
9 9 A b H 3X S+ 0 0 0 40 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
10 10 A Y H 3X S+ 0 0 68 40 68 YYYYYYGYYAYAAYYYAAWRLWYWWWPWLLYWWLLWYWL
11 11 A A H S+ 0 0 50 40 57 PPPPPPPPPPHPPHHHPPPPKPHVVPKPKAPVVPPVPAA
13 13 A c H X>S+ 0 0 4 40 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
14 14 A R H <5S+ 0 0 198 39 50 RMKQRKQQKRRRRKKRRRKAKKEKKR.KKKEENKKKRKK
15 15 A K H <5S+ 0 0 181 40 70 KKRKYKQKQKEKKKKEKKARAAGQQRRAQAKKQAAQGKA
16 16 A Q H <5S- 0 0 129 40 80 QQKRIEQLQQKEEEEKQQAAQAIMMVAAAAKLMQQMVVA
17 17 A T T <5S- 0 0 65 40 62 TTTTTTTTTTTTTTTTTTTTGFTFFTQVTVYYFFFFTTV
18 18 A G < - 0 0 44 39 8 GGGGGGGGGGGGGGGGGGGG.GGGGGGGGGNNGGGGGGG
19 19 A c - 0 0 12 40 78 CCCCCCCCCCCCCYYCCCKYCVKKKSCTRKCTKQIKRSK
20 20 A P S S- 0 0 85 40 70 PPPPFPPLTPMPPPPPPPAYKDRPPAKDPAASPSRPATA
21 21 A N S S- 0 0 100 40 67 NNNNNRNNNHNHYNNNHHASSRSNNQNRNARRNAANHQA
22 22 A A - 0 0 10 40 33 AAAASASASAGGGAAGGGGSGGGGGAGGGGAGGggGGGG
23 23 A K E -A 30 0A 117 40 2 KKKKRKKKKKKKKKKKKKKKKKKKKKKKKKKKKkkKKKK
24 24 A a E -A 29 0A 20 40 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
25 25 A I - 0 0 77 40 36 IIMIIIIMMMIMMMMIMMMIMMIMMQMMMMMMMMMMMQM
26 26 A N S S+ 0 0 108 40 10 NNNNNNNNNNNNNNNDNNNNNGNNNNNGNNNNNNNNNNN
27 27 A K S S- 0 0 147 39 62 KKKKKRRKKKRRRRR RRKGKKKGGNRKRGRKGGGGGKG
28 28 A S - 0 0 40 39 67 SSSTSNMAVTVKKKK TTKSKKKKKQKKKKHKKKKKRQK
29 29 A b E -A 24 0A 30 39 0 CCCCCCCCCCCCCCC CCCCCCCCCCCCCCCCCCCCCCC
30 30 A K E -A 23 0A 115 39 41 KKKKKKKKKRKKKKK RRKVKKYRRRKRKKNRRKKRTRK
31 31 A d - 0 0 21 39 0 CCCCCCCCCCCCCCC CCCCCCCCCCCCCCCCCCCCCCC
32 32 A Y S S+ 0 0 165 38 26 YYYYYYYYYHYNNFF NN YYYYYYYYYYYYYYYYYYYY
33 33 A G 0 0 45 26 70 GGGGGGGGGRGRRGG RR G SS Y nSS S
34 34 A d 0 0 89 18 0 CCCCCCCCCCCCC CC C c
## SEQUENCE PROFILE AND ENTROPY
SeqNo PDBNo V L I M F W Y G A P S T C H R K Q E N D NOCC NDEL NINS ENTROPY RELENT WEIGHT
1 1 A 47 0 50 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 0.800 26 0.83
2 2 A 0 0 0 0 0 0 0 0 0 3 28 0 0 0 28 38 0 0 0 3 39 0 0 1.269 42 0.44
3 3 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 40 0 0 0.000 0 1.00
4 4 A 5 0 0 0 0 0 5 5 0 0 13 43 0 0 20 3 5 0 3 0 40 0 0 1.729 57 0.20
5 5 A 5 3 0 0 0 0 0 50 8 0 10 17 0 0 0 0 0 0 5 3 40 0 0 1.560 52 0.44
6 6 A 0 0 0 0 0 0 0 0 0 20 68 10 0 0 0 0 0 3 0 0 40 0 0 0.910 30 0.59
7 7 A 0 0 0 0 0 0 0 0 0 3 13 0 0 0 13 68 0 0 5 0 40 0 0 1.027 34 0.59
8 8 A 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 35 30 0 32 40 0 0 1.186 39 0.63
9 9 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 40 0 0 0.000 0 1.00
10 10 A 0 15 0 0 0 25 40 3 13 3 0 0 0 0 3 0 0 0 0 0 40 0 0 1.534 51 0.31
11 11 A 3 0 5 0 0 0 0 10 13 32 10 0 0 0 5 3 0 8 0 13 40 0 0 2.024 67 0.25
12 12 A 13 0 0 0 0 0 0 0 8 60 0 0 0 13 0 8 0 0 0 0 40 0 0 1.215 40 0.42
13 13 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 40 1 0 0.000 0 1.00
14 14 A 0 0 0 3 0 0 0 0 3 0 0 0 0 0 31 46 8 8 3 0 39 0 0 1.396 46 0.49
15 15 A 0 0 0 0 0 0 3 5 20 0 0 0 0 0 10 40 17 5 0 0 40 0 0 1.615 53 0.30
16 16 A 8 5 5 10 0 0 0 0 20 0 0 0 0 0 3 10 28 13 0 0 40 0 0 1.983 66 0.20
17 17 A 8 0 0 0 17 0 5 3 0 0 0 65 0 0 0 0 3 0 0 0 40 1 0 1.114 37 0.37
18 18 A 0 0 0 0 0 0 0 95 0 0 0 0 0 0 0 0 0 0 5 0 39 0 0 0.202 6 0.92
19 19 A 3 0 3 0 0 0 8 0 0 0 5 5 50 0 5 20 3 0 0 0 40 0 0 1.589 53 0.21
20 20 A 0 3 0 3 3 0 3 0 15 50 5 5 0 0 5 5 0 0 0 5 40 0 0 1.749 58 0.30
21 21 A 0 0 0 0 0 0 3 0 13 0 8 0 0 13 13 0 5 0 47 0 40 0 0 1.570 52 0.33
22 22 A 0 0 0 0 0 0 0 60 30 0 10 0 0 0 0 0 0 0 0 0 40 0 2 0.898 29 0.67
23 23 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 98 0 0 0 0 40 0 0 0.117 3 0.98
24 24 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 40 0 0 0.000 0 1.00
25 25 A 0 0 28 68 0 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 40 0 0 0.770 25 0.64
26 26 A 0 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 0 93 3 40 0 0 0.314 10 0.90
27 27 A 0 0 0 0 0 0 0 26 0 0 0 0 0 0 31 41 0 0 3 0 39 0 0 1.171 39 0.37
28 28 A 5 0 0 3 0 0 0 0 3 0 15 10 0 3 3 51 5 0 3 0 39 0 0 1.638 54 0.33
29 29 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 39 0 0 0.000 0 1.00
30 30 A 3 0 0 0 0 0 3 0 0 0 0 3 0 0 28 62 0 0 3 0 39 0 0 1.032 34 0.59
31 31 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 39 0 0 0.000 0 1.00
32 32 A 0 0 0 0 5 0 82 0 0 0 0 0 0 3 0 0 0 0 11 0 38 0 0 0.654 21 0.73
33 33 A 0 0 0 0 0 0 4 54 0 0 19 0 0 0 19 0 0 0 4 0 26 0 1 1.218 40 0.30
34 34 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 18 0 0 0.000 0 1.00
## INSERTION LIST
AliNo IPOS JPOS Len Sequence
31 34 59 1 nNc
34 23 27 1 gAk
35 23 27 1 gAk
//