Complet list of 1q69 hssp file
Complete list of 1q69.hssp file
HSSP HOMOLOGY DERIVED SECONDARY STRUCTURE OF PROTEINS , VERSION 2.0 2011
PDBID 1Q69
THRESHOLD according to: t(L)=(290.15 * L ** -0.562) + 5
REFERENCE Sander C., Schneider R. : Database of homology-derived protein structures. Proteins, 9:56-68 (1991).
CONTACT Maintained at http://www.cmbi.ru.nl/ by Maarten L. Hekkelman
DATE file generated on 2014-05-06
HEADER MEMBRANE PROTEIN/TRANSFERASE 12-AUG-03 1Q69
COMPND MOL_ID: 1; MOLECULE: T-CELL SURFACE GLYCOPROTEIN CD8 ALPHA CHAIN; CHAI
SOURCE MOL_ID: 1; ORGANISM_SCIENTIFIC: HOMO SAPIENS; ORGANISM_COMMON: HUMAN;
AUTHOR P.W.KIM,Z.Y.SUN,S.C.BLACKLOW,G.WAGNER,M.J.ECK
DBREF 1Q69 A 188 206 UNP P01732 CD8A_HUMAN 209 227
DBREF 1Q69 B 7 35 UNP P06239 LCK_HUMAN 6 34
SEQLENGTH 29
NCHAIN 1 chain(s) in 1Q69 data set
NALIGN 48
NOTATION : ID: EMBL/SWISSPROT identifier of the aligned (homologous) protein
NOTATION : STRID: if the 3-D structure of the aligned protein is known, then STRID is the Protein Data Bank identifier as taken
NOTATION : from the database reference or DR-line of the EMBL/SWISSPROT entry
NOTATION : %IDE: percentage of residue identity of the alignment
NOTATION : %SIM (%WSIM): (weighted) similarity of the alignment
NOTATION : IFIR/ILAS: first and last residue of the alignment in the test sequence
NOTATION : JFIR/JLAS: first and last residue of the alignment in the alignend protein
NOTATION : LALI: length of the alignment excluding insertions and deletions
NOTATION : NGAP: number of insertions and deletions in the alignment
NOTATION : LGAP: total length of all insertions and deletions
NOTATION : LSEQ2: length of the entire sequence of the aligned protein
NOTATION : ACCNUM: SwissProt accession number
NOTATION : PROTEIN: one-line description of aligned protein
NOTATION : SeqNo,PDBNo,AA,STRUCTURE,BP1,BP2,ACC: sequential and PDB residue numbers, amino acid (lower case = Cys), secondary
NOTATION : structure, bridge partners, solvent exposure as in DSSP (Kabsch and Sander, Biopolymers 22, 2577-2637(1983)
NOTATION : VAR: sequence variability on a scale of 0-100 as derived from the NALIGN alignments
NOTATION : pair of lower case characters (AvaK) in the alignend sequence bracket a point of insertion in this sequence
NOTATION : dots (....) in the alignend sequence indicate points of deletion in this sequence
NOTATION : SEQUENCE PROFILE: relative frequency of an amino acid type at each position. Asx and Glx are in their
NOTATION : acid/amide form in proportion to their database frequencies
NOTATION : NOCC: number of aligned sequences spanning this position (including the test sequence)
NOTATION : NDEL: number of sequences with a deletion in the test protein at this position
NOTATION : NINS: number of sequences with an insertion in the test protein at this position
NOTATION : ENTROPY: entropy measure of sequence variability at this position
NOTATION : RELENT: relative entropy, i.e. entropy normalized to the range 0-100
NOTATION : WEIGHT: conservation weight
## PROTEINS : identifier and alignment statistics
NR. ID STRID %IDE %WSIM IFIR ILAS JFIR JLAS LALI NGAP LGAP LSEQ2 ACCNUM PROTEIN
1 : B4DZS7_HUMAN 0.97 1.00 1 29 51 79 29 0 0 536 B4DZS7 cDNA FLJ56184, highly similar to Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) OS=Homo sapiens PE=2 SV=1
2 : E9PAP0_HUMAN 0.97 1.00 1 29 51 79 29 0 0 285 E9PAP0 Tyrosine-protein kinase Lck (Fragment) OS=Homo sapiens GN=LCK PE=2 SV=1
3 : E9PI33_HUMAN 0.97 1.00 1 29 51 79 29 0 0 168 E9PI33 Tyrosine-protein kinase Lck (Fragment) OS=Homo sapiens GN=LCK PE=2 SV=1
4 : E9PJ92_HUMAN 0.97 1.00 1 29 7 35 29 0 0 319 E9PJ92 Tyrosine-protein kinase Lck (Fragment) OS=Homo sapiens GN=LCK PE=2 SV=1
5 : E9PKQ8_HUMAN 0.97 1.00 1 29 7 35 29 0 0 200 E9PKQ8 Tyrosine-protein kinase Lck (Fragment) OS=Homo sapiens GN=LCK PE=2 SV=1
6 : E9PQ10_HUMAN 0.97 1.00 1 29 7 35 29 0 0 149 E9PQ10 Tyrosine-protein kinase Lck (Fragment) OS=Homo sapiens GN=LCK PE=2 SV=1
7 : F8W6B9_HUMAN 0.97 1.00 1 29 7 35 29 0 0 137 F8W6B9 Tyrosine-protein kinase Lck (Fragment) OS=Homo sapiens GN=LCK PE=2 SV=1
8 : G3QJD4_GORGO 0.97 1.00 1 29 7 35 29 0 0 539 G3QJD4 Uncharacterized protein OS=Gorilla gorilla gorilla GN=101151112 PE=4 SV=1
9 : G7MI89_MACMU 0.97 1.00 1 29 7 35 29 0 0 509 G7MI89 Putative uncharacterized protein OS=Macaca mulatta GN=EGK_00506 PE=4 SV=1
10 : H9Z8V0_MACMU 0.97 1.00 1 29 7 35 29 0 0 509 H9Z8V0 Tyrosine-protein kinase Lck OS=Macaca mulatta GN=LCK PE=2 SV=1
11 : LCK_HUMAN 0.97 1.00 1 29 7 35 29 0 0 509 P06239 Tyrosine-protein kinase Lck OS=Homo sapiens GN=LCK PE=1 SV=6
12 : Q573B4_HUMAN 0.97 1.00 1 29 7 35 29 0 0 516 Q573B4 Proto-oncogene tyrosine-protein kinase LCK OS=Homo sapiens GN=LCK PE=2 SV=1
13 : Q95M32_9PRIM 0.97 1.00 1 29 7 35 29 0 0 509 Q95M32 Lck protein OS=Hylobates sp. GN=lck PE=2 SV=1
14 : I3MIH9_SPETR 0.93 1.00 1 29 7 35 29 0 0 509 I3MIH9 Uncharacterized protein OS=Spermophilus tridecemlineatus GN=LCK PE=4 SV=1
15 : LCK_AOTNA 0.93 1.00 1 29 7 35 29 0 0 509 Q5PXS1 Tyrosine-protein kinase Lck OS=Aotus nancymaae GN=LCK PE=2 SV=4
16 : M3ZC45_NOMLE 0.93 1.00 1 29 7 35 29 0 0 93 M3ZC45 Uncharacterized protein OS=Nomascus leucogenys PE=4 SV=1
17 : B7U173_SHEEP 0.90 0.97 1 29 7 35 29 0 0 509 B7U173 Lymphocyte-specific protein tyrosine kinase OS=Ovis aries GN=LCK PE=2 SV=1
18 : E2R589_CANFA 0.90 1.00 1 29 7 35 29 0 0 539 E2R589 Uncharacterized protein OS=Canis familiaris GN=LCK PE=4 SV=2
19 : F1SV94_PIG 0.90 1.00 1 29 7 35 29 0 0 509 F1SV94 Uncharacterized protein OS=Sus scrofa GN=LCK PE=4 SV=2
20 : F6USJ9_HORSE 0.90 1.00 1 29 7 35 29 0 0 510 F6USJ9 Uncharacterized protein OS=Equus caballus GN=LCK PE=4 SV=1
21 : G1LMC0_AILME 0.90 1.00 1 29 50 78 29 0 0 537 G1LMC0 Uncharacterized protein (Fragment) OS=Ailuropoda melanoleuca GN=LCK PE=4 SV=1
22 : G1LMD8_AILME 0.90 1.00 1 29 7 35 29 0 0 539 G1LMD8 Uncharacterized protein OS=Ailuropoda melanoleuca GN=LCK PE=4 SV=1
23 : G1P745_MYOLU 0.90 1.00 1 29 7 35 29 0 0 510 G1P745 Uncharacterized protein OS=Myotis lucifugus GN=LCK PE=4 SV=1
24 : G5BU89_HETGA 0.90 1.00 1 29 7 35 29 0 0 509 G5BU89 Proto-oncogene tyrosine-protein kinase LCK OS=Heterocephalus glaber GN=GW7_09311 PE=4 SV=1
25 : J9P4H4_CANFA 0.90 1.00 1 29 7 35 29 0 0 509 J9P4H4 Uncharacterized protein OS=Canis familiaris GN=LCK PE=4 SV=1
26 : LCK_SAISC 0.90 0.97 1 29 7 35 29 0 0 509 Q95KR7 Proto-oncogene tyrosine-protein kinase LCK OS=Saimiri sciureus GN=LCK PE=1 SV=3
27 : M3WH17_FELCA 0.90 1.00 1 29 7 35 29 0 0 509 M3WH17 Uncharacterized protein OS=Felis catus GN=LCK PE=4 SV=1
28 : Q3ZCM0_BOVIN 0.90 0.97 1 29 7 35 29 0 0 509 Q3ZCM0 Lymphocyte-specific protein tyrosine kinase OS=Bos taurus GN=LCK PE=2 SV=1
29 : S7NDD9_MYOBR 0.90 1.00 1 29 33 61 29 0 0 535 S7NDD9 Tyrosine-protein kinase Lck OS=Myotis brandtii GN=D623_10012386 PE=4 SV=1
30 : W5QII1_SHEEP 0.90 0.97 1 29 45 73 29 0 0 533 W5QII1 Uncharacterized protein (Fragment) OS=Ovis aries GN=LCK PE=4 SV=1
31 : W5QII2_SHEEP 0.90 0.97 1 29 7 35 29 0 0 559 W5QII2 Uncharacterized protein OS=Ovis aries GN=LCK PE=4 SV=1
32 : B2KG65_MOUSE 0.89 1.00 1 27 7 33 27 0 0 92 B2KG65 Proto-oncogene tyrosine-protein kinase LCK (Fragment) OS=Mus musculus GN=Lck PE=2 SV=1
33 : E9Q696_MOUSE 0.89 1.00 1 27 18 44 27 0 0 520 E9Q696 Proto-oncogene tyrosine-protein kinase LCK OS=Mus musculus GN=Lck PE=2 SV=1
34 : LCK_MOUSE 0.89 1.00 1 27 7 33 27 0 0 509 P06240 Proto-oncogene tyrosine-protein kinase LCK OS=Mus musculus GN=Lck PE=1 SV=4
35 : B8XSK4_PIG 0.86 1.00 1 29 7 35 29 0 0 509 B8XSK4 Lymphocyte-specific protein tyrosine kinase OS=Sus scrofa GN=LCK PE=2 SV=1
36 : G1SK64_RABIT 0.86 1.00 1 29 7 35 29 0 0 510 G1SK64 Uncharacterized protein OS=Oryctolagus cuniculus GN=LCK PE=4 SV=1
37 : G3T7L2_LOXAF 0.86 1.00 1 28 7 34 28 0 0 539 G3T7L2 Uncharacterized protein OS=Loxodonta africana GN=LCK PE=4 SV=1
38 : H0WSN1_OTOGA 0.86 1.00 1 29 7 35 29 0 0 509 H0WSN1 Uncharacterized protein OS=Otolemur garnettii GN=LCK PE=4 SV=1
39 : L5JRQ5_PTEAL 0.86 1.00 1 28 7 34 28 0 0 509 L5JRQ5 Proto-oncogene tyrosine-protein kinase LCK OS=Pteropus alecto GN=PAL_GLEAN10015012 PE=4 SV=1
40 : L9JDG6_TUPCH 0.86 0.97 1 29 7 35 29 0 0 444 L9JDG6 Tyrosine-protein kinase Lck OS=Tupaia chinensis GN=TREES_T100020918 PE=4 SV=1
41 : LCK_RAT 0.86 1.00 1 29 7 35 29 0 0 509 Q01621 Proto-oncogene tyrosine-protein kinase LCK OS=Rattus norvegicus GN=Lck PE=2 SV=3
42 : S9YJ22_9CETA 0.86 0.97 1 29 7 35 29 0 0 509 S9YJ22 Tyrosine-protein kinase Lck isoform 2 OS=Camelus ferus GN=CB1_000256026 PE=4 SV=1
43 : V5IZL0_MESAU 0.86 0.97 1 29 7 35 29 0 0 509 V5IZL0 Lymphocyte-specific tyrosine kinase OS=Mesocricetus auratus GN=LCK PE=2 SV=1
44 : M3YUZ1_MUSPF 0.83 1.00 1 29 7 35 29 0 0 509 M3YUZ1 Uncharacterized protein OS=Mustela putorius furo GN=LCK PE=4 SV=1
45 : U6DAS6_NEOVI 0.83 1.00 1 29 7 35 29 0 0 423 U6DAS6 Tyrosine-protein kinase Lck (Fragment) OS=Neovison vison GN=LCK PE=2 SV=1
46 : G3W363_SARHA 0.80 0.96 4 28 10 34 25 0 0 509 G3W363 Uncharacterized protein OS=Sarcophilus harrisii GN=LCK PE=4 SV=1
47 : H0VAT0_CAVPO 0.79 0.93 1 29 7 35 29 0 0 509 H0VAT0 Uncharacterized protein OS=Cavia porcellus GN=LCK PE=4 SV=1
48 : F6Z574_MONDO 0.76 0.96 4 28 10 34 25 0 0 509 F6Z574 Uncharacterized protein OS=Monodelphis domestica GN=LCK PE=4 SV=2
## ALIGNMENTS 1 - 48
SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
1 7 B S 0 0 143 47 0 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS S
2 8 B H - 0 0 165 47 42 HHHHHHHHHHHHHNHHNNNNNNNNNHNNNNNNNNNNNNNNNNNNN N
3 9 B P - 0 0 106 47 20 PPPPPPPPPPPPPPPSPPPPPPPPPLPPPPPPPPPPPPPPPPPSS P
4 10 B E + 0 0 141 49 3 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEED
5 11 B D + 0 0 90 49 10 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEEEDE
6 12 B D + 0 0 147 49 0 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
7 13 B W S > S- 0 0 95 49 0 WWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWW
8 14 B L T 4 S- 0 0 136 49 0 MMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMM
9 15 B E T 4 S- 0 0 98 49 0 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE
10 16 B N T 4 S+ 0 0 70 49 3 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNN
11 17 B I < - 0 0 15 49 0 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
12 18 B D E -A 41 0A 91 49 0 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
13 19 B V E -A 40 0A 67 49 0 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVV
14 20 B C >> - 0 0 18 49 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
15 21 B E T 34 S+ 0 0 177 49 3 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEGEEEEEEEE
16 22 B N T 34 S+ 0 0 132 49 18 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNRNR
17 23 B C T <4 S- 0 0 27 49 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
18 24 B H S < S+ 0 0 154 49 3 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHRHHHHHHHHHHHHH
19 25 B Y S S- 0 0 85 49 2 YYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYCY
20 26 B P E -A 33 0A 29 49 0 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP
21 27 B I E +A 32 0A 64 49 0 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
22 28 B V - 0 0 41 49 8 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVDV
23 29 B P - 0 0 75 49 3 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPSPPPPPPPPP
24 30 B L - 0 0 182 49 0 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
25 31 B D + 0 0 100 49 1 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDD
26 32 B G + 0 0 79 49 30 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGSSSGGSGGGSVSGGASA
27 33 B K + 0 0 172 49 0 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
28 34 B G 0 0 65 46 51 GGGGGGGGGGGGGGAGTAAAAAAAAAATATT AAAAAASATAASAD
29 35 B T 0 0 204 42 0 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TT T TTTTTT T
## SEQUENCE PROFILE AND ENTROPY
SeqNo PDBNo V L I M F W Y G A P S T C H R K Q E N D NOCC NDEL NINS ENTROPY RELENT WEIGHT
1 7 B 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 47 0 0 0.000 0 1.00
2 8 B 0 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 0 0 64 0 47 0 0 0.654 21 0.57
3 9 B 0 2 0 0 0 0 0 0 0 91 6 0 0 0 0 0 0 0 0 0 47 0 0 0.339 11 0.79
4 10 B 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 98 0 2 49 0 0 0.100 3 0.96
5 11 B 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 92 49 0 0 0.283 9 0.90
6 12 B 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 49 0 0 0.000 0 1.00
7 13 B 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 49 0 0 0.000 0 1.00
8 14 B 0 2 0 98 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 49 0 0 0.100 3 0.99
9 15 B 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 49 0 0 0.000 0 1.00
10 16 B 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 98 0 49 0 0 0.100 3 0.96
11 17 B 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 49 0 0 0.000 0 1.00
12 18 B 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 49 0 0 0.000 0 1.00
13 19 B 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 49 0 0 0.000 0 1.00
14 20 B 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 49 0 0 0.000 0 1.00
15 21 B 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 98 0 0 49 0 0 0.100 3 0.97
16 22 B 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 96 0 49 0 0 0.171 5 0.82
17 23 B 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 49 0 0 0.000 0 1.00
18 24 B 0 0 0 0 0 0 0 0 0 0 0 0 0 98 2 0 0 0 0 0 49 0 0 0.100 3 0.97
19 25 B 0 0 0 0 0 0 98 0 0 0 0 0 2 0 0 0 0 0 0 0 49 0 0 0.100 3 0.97
20 26 B 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 49 0 0 0.000 0 1.00
21 27 B 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 49 0 0 0.000 0 1.00
22 28 B 98 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 49 0 0 0.100 3 0.91
23 29 B 0 0 0 0 0 0 0 0 0 98 2 0 0 0 0 0 0 0 0 0 49 0 0 0.100 3 0.96
24 30 B 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 49 0 0 0.000 0 1.00
25 31 B 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 98 49 0 0 0.100 3 0.98
26 32 B 2 0 0 0 0 0 0 80 4 0 14 0 0 0 0 0 0 0 0 0 49 0 0 0.670 22 0.70
27 33 B 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 49 0 0 0.000 0 1.00
28 34 B 0 0 0 0 0 0 0 35 48 0 4 11 0 0 0 0 0 0 0 2 46 0 0 1.181 39 0.48
29 35 B 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 42 0 0 0.000 0 1.00
## INSERTION LIST
AliNo IPOS JPOS Len Sequence
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