Complet list of 1pls hssp file
Complete list of 1pls.hssp file
HSSP HOMOLOGY DERIVED SECONDARY STRUCTURE OF PROTEINS , VERSION 2.0 2011
PDBID 1PLS
THRESHOLD according to: t(L)=(290.15 * L ** -0.562) + 5
REFERENCE Sander C., Schneider R. : Database of homology-derived protein structures. Proteins, 9:56-68 (1991).
CONTACT Maintained at http://www.cmbi.ru.nl/ by Maarten L. Hekkelman
DATE file generated on 2014-05-06
HEADER PHOSPHORYLATION 03-MAY-94 1PLS
COMPND MOL_ID: 1; MOLECULE: PLECKSTRIN HOMOLOGY DOMAIN; CHAIN: A; ENGINEERED:
SOURCE MOL_ID: 1; ORGANISM_SCIENTIFIC: HOMO SAPIENS; ORGANISM_COMMON: HUMAN;
AUTHOR H.S.YOON,P.J.HAJDUK,A.M.PETROS,E.T.OLEJNICZAK,R.P.MEADOWS, S.W.FESIK
DBREF 1PLS A 1 105 UNP P08567 PLEK_HUMAN 1 105
SEQLENGTH 113
NCHAIN 1 chain(s) in 1PLS data set
NALIGN 188
NOTATION : ID: EMBL/SWISSPROT identifier of the aligned (homologous) protein
NOTATION : STRID: if the 3-D structure of the aligned protein is known, then STRID is the Protein Data Bank identifier as taken
NOTATION : from the database reference or DR-line of the EMBL/SWISSPROT entry
NOTATION : %IDE: percentage of residue identity of the alignment
NOTATION : %SIM (%WSIM): (weighted) similarity of the alignment
NOTATION : IFIR/ILAS: first and last residue of the alignment in the test sequence
NOTATION : JFIR/JLAS: first and last residue of the alignment in the alignend protein
NOTATION : LALI: length of the alignment excluding insertions and deletions
NOTATION : NGAP: number of insertions and deletions in the alignment
NOTATION : LGAP: total length of all insertions and deletions
NOTATION : LSEQ2: length of the entire sequence of the aligned protein
NOTATION : ACCNUM: SwissProt accession number
NOTATION : PROTEIN: one-line description of aligned protein
NOTATION : SeqNo,PDBNo,AA,STRUCTURE,BP1,BP2,ACC: sequential and PDB residue numbers, amino acid (lower case = Cys), secondary
NOTATION : structure, bridge partners, solvent exposure as in DSSP (Kabsch and Sander, Biopolymers 22, 2577-2637(1983)
NOTATION : VAR: sequence variability on a scale of 0-100 as derived from the NALIGN alignments
NOTATION : pair of lower case characters (AvaK) in the alignend sequence bracket a point of insertion in this sequence
NOTATION : dots (....) in the alignend sequence indicate points of deletion in this sequence
NOTATION : SEQUENCE PROFILE: relative frequency of an amino acid type at each position. Asx and Glx are in their
NOTATION : acid/amide form in proportion to their database frequencies
NOTATION : NOCC: number of aligned sequences spanning this position (including the test sequence)
NOTATION : NDEL: number of sequences with a deletion in the test protein at this position
NOTATION : NINS: number of sequences with an insertion in the test protein at this position
NOTATION : ENTROPY: entropy measure of sequence variability at this position
NOTATION : RELENT: relative entropy, i.e. entropy normalized to the range 0-100
NOTATION : WEIGHT: conservation weight
## PROTEINS : identifier and alignment statistics
NR. ID STRID %IDE %WSIM IFIR ILAS JFIR JLAS LALI NGAP LGAP LSEQ2 ACCNUM PROTEIN
1 : D2HS16_AILME 0.99 1.00 15 105 1 91 91 0 0 336 D2HS16 Putative uncharacterized protein (Fragment) OS=Ailuropoda melanoleuca GN=PANDA_014836 PE=4 SV=1
2 : G3QSR3_GORGO 0.99 1.00 15 105 17 107 91 0 0 309 G3QSR3 Uncharacterized protein (Fragment) OS=Gorilla gorilla gorilla PE=4 SV=1
3 : G3RWG4_GORGO 0.99 1.00 1 105 1 105 105 0 0 350 G3RWG4 Uncharacterized protein OS=Gorilla gorilla gorilla GN=101126585 PE=4 SV=1
4 : H2P602_PONAB 0.99 1.00 1 105 1 105 105 0 0 350 H2P602 Uncharacterized protein OS=Pongo abelii GN=PLEK PE=4 SV=1
5 : PLEK_HUMAN 0.99 1.00 1 105 1 105 105 0 0 350 P08567 Pleckstrin OS=Homo sapiens GN=PLEK PE=1 SV=3
6 : Q59GZ2_HUMAN 0.99 1.00 1 105 19 123 105 0 0 308 Q59GZ2 PLEK protein variant (Fragment) OS=Homo sapiens PE=2 SV=1
7 : F7ACJ1_HORSE 0.98 1.00 1 105 2 106 105 0 0 351 F7ACJ1 Uncharacterized protein (Fragment) OS=Equus caballus GN=PLEK PE=4 SV=1
8 : F7FZB4_CALJA 0.98 1.00 1 105 19 123 105 0 0 308 F7FZB4 Uncharacterized protein (Fragment) OS=Callithrix jacchus GN=PLEK PE=4 SV=1
9 : F7HM67_MACMU 0.98 1.00 1 105 1 105 105 0 0 350 F7HM67 Uncharacterized protein OS=Macaca mulatta GN=PLEK PE=4 SV=1
10 : G1LE87_AILME 0.98 1.00 1 105 1 105 105 0 0 351 G1LE87 Uncharacterized protein OS=Ailuropoda melanoleuca GN=PLEK PE=4 SV=1
11 : G1PUS2_MYOLU 0.98 1.00 1 105 1 105 105 0 0 350 G1PUS2 Uncharacterized protein OS=Myotis lucifugus GN=PLEK PE=4 SV=1
12 : G1RG53_NOMLE 0.98 1.00 1 105 1 105 105 0 0 350 G1RG53 Uncharacterized protein OS=Nomascus leucogenys GN=PLEK PE=4 SV=1
13 : G7PMC7_MACFA 0.98 1.00 1 105 1 105 105 0 0 350 G7PMC7 Putative uncharacterized protein OS=Macaca fascicularis GN=EGM_04866 PE=4 SV=1
14 : M3WBE7_FELCA 0.98 1.00 1 105 1 105 105 0 0 350 M3WBE7 Uncharacterized protein OS=Felis catus GN=PLEK PE=4 SV=1
15 : PLEK_MOUSE 0.98 1.00 1 105 1 105 105 0 0 350 Q9JHK5 Pleckstrin OS=Mus musculus GN=Plek PE=1 SV=1
16 : Q5F271_MOUSE 0.98 1.00 1 105 1 105 105 0 0 350 Q5F271 Pleckstrin OS=Mus musculus GN=Plek PE=2 SV=1
17 : Q8C6F4_MOUSE 0.98 1.00 1 105 1 105 105 0 0 350 Q8C6F4 Putative uncharacterized protein OS=Mus musculus GN=Plek PE=2 SV=1
18 : S7NN86_MYOBR 0.98 1.00 1 105 1 105 105 0 0 350 S7NN86 Pleckstrin OS=Myotis brandtii GN=D623_10034252 PE=4 SV=1
19 : S9XT76_9CETA 0.98 1.00 1 105 1 105 105 0 0 322 S9XT76 Pleckstrin-like protein OS=Camelus ferus GN=CB1_001866028 PE=4 SV=1
20 : U3FW63_CALJA 0.98 1.00 1 105 1 105 105 0 0 350 U3FW63 Pleckstrin OS=Callithrix jacchus GN=PLEK PE=2 SV=1
21 : G3UNG1_LOXAF 0.97 0.99 1 105 1 105 105 0 0 350 G3UNG1 Uncharacterized protein OS=Loxodonta africana GN=PLEK PE=4 SV=1
22 : G9KH42_MUSPF 0.97 1.00 1 105 1 105 105 0 0 350 G9KH42 Pleckstrin (Fragment) OS=Mustela putorius furo PE=2 SV=1
23 : H0XFT8_OTOGA 0.97 0.98 17 105 18 106 89 0 0 351 H0XFT8 Uncharacterized protein (Fragment) OS=Otolemur garnettii GN=PLEK PE=4 SV=1
24 : H2QI07_PANTR 0.97 1.00 1 105 1 105 105 0 0 350 H2QI07 Uncharacterized protein OS=Pan troglodytes GN=PLEK PE=4 SV=1
25 : H9YZS4_MACMU 0.97 0.99 1 105 1 105 105 0 0 350 H9YZS4 Pleckstrin OS=Macaca mulatta GN=PLEK PE=2 SV=1
26 : L9KMX2_TUPCH 0.97 1.00 1 105 1 105 105 0 0 322 L9KMX2 Pleckstrin OS=Tupaia chinensis GN=TREES_T100006648 PE=4 SV=1
27 : M3Y4G9_MUSPF 0.97 1.00 1 105 1 105 105 0 0 350 M3Y4G9 Uncharacterized protein OS=Mustela putorius furo GN=PLEK PE=4 SV=1
28 : U6CTN5_NEOVI 0.97 1.00 1 105 1 105 105 0 0 350 U6CTN5 Pleckstrin OS=Neovison vison GN=PLEK PE=2 SV=1
29 : F1SJ07_PIG 0.96 1.00 1 105 1 105 105 0 0 350 F1SJ07 Pleckstrin OS=Sus scrofa GN=PLEK PE=2 SV=2
30 : I3L746_PIG 0.96 1.00 1 105 1 105 105 0 0 335 I3L746 Uncharacterized protein OS=Sus scrofa PE=4 SV=1
31 : PLEK_CANFA 0.96 0.99 1 105 1 105 105 0 0 351 Q6Q308 Pleckstrin OS=Canis familiaris GN=PLEK PE=2 SV=1
32 : PLEK_RAT 0.96 1.00 1 105 1 105 105 0 0 350 Q4KM33 Pleckstrin OS=Rattus norvegicus GN=Plek PE=2 SV=1
33 : F1MRZ8_BOVIN 0.95 0.99 1 105 1 105 105 0 0 350 F1MRZ8 Uncharacterized protein OS=Bos taurus GN=PLEK PE=4 SV=2
34 : L5KT99_PTEAL 0.95 0.99 1 105 1 105 105 0 0 350 L5KT99 Pleckstrin OS=Pteropus alecto GN=PAL_GLEAN10021181 PE=4 SV=1
35 : W5QF71_SHEEP 0.95 0.99 1 105 1 105 105 0 0 350 W5QF71 Uncharacterized protein OS=Ovis aries GN=PLEK PE=4 SV=1
36 : F7AZ99_MONDO 0.92 1.00 1 105 1 105 105 0 0 350 F7AZ99 Uncharacterized protein OS=Monodelphis domestica GN=PLEK PE=4 SV=1
37 : G3VFV4_SARHA 0.92 0.99 1 105 1 105 105 0 0 350 G3VFV4 Uncharacterized protein OS=Sarcophilus harrisii GN=PLEK PE=4 SV=1
38 : G3SWS0_LOXAF 0.91 0.94 2 105 2 105 104 0 0 350 G3SWS0 Uncharacterized protein (Fragment) OS=Loxodonta africana GN=PLEK PE=4 SV=1
39 : G3HEF8_CRIGR 0.90 0.94 24 112 1 89 89 0 0 327 G3HEF8 Pleckstrin OS=Cricetulus griseus GN=I79_008942 PE=4 SV=1
40 : H0V129_CAVPO 0.90 0.98 1 105 1 105 105 0 0 350 H0V129 Uncharacterized protein OS=Cavia porcellus GN=PLEK PE=4 SV=1
41 : Q8CAG6_MOUSE 0.90 0.94 24 112 1 89 89 0 0 327 Q8CAG6 Pleckstrin OS=Mus musculus GN=Plek PE=2 SV=1
42 : G5BA19_HETGA 0.89 0.98 1 105 1 105 105 0 0 350 G5BA19 Pleckstrin OS=Heterocephalus glaber GN=GW7_02211 PE=4 SV=1
43 : F1NSA0_CHICK 0.88 0.98 2 105 4 107 104 0 0 353 F1NSA0 Uncharacterized protein OS=Gallus gallus GN=PLEK PE=4 SV=1
44 : F7GBC9_CALJA 0.88 0.93 2 105 2 105 104 0 0 350 F7GBC9 Uncharacterized protein (Fragment) OS=Callithrix jacchus GN=PLEK PE=4 SV=1
45 : G3VFV5_SARHA 0.88 0.97 6 105 1 100 100 0 0 345 G3VFV5 Uncharacterized protein (Fragment) OS=Sarcophilus harrisii GN=PLEK PE=4 SV=1
46 : K7FV50_PELSI 0.88 0.98 2 105 4 107 104 0 0 353 K7FV50 Uncharacterized protein OS=Pelodiscus sinensis GN=PLEK PE=4 SV=1
47 : Q9W6Q0_CHICK 0.88 0.98 2 105 4 107 104 0 0 353 Q9W6Q0 Pleckstrin OS=Gallus gallus PE=2 SV=1
48 : F6XMG8_ORNAN 0.87 0.97 1 105 1 105 105 0 0 350 F6XMG8 Uncharacterized protein OS=Ornithorhynchus anatinus GN=LOC100085261 PE=4 SV=2
49 : R7VTT2_COLLI 0.87 0.98 2 105 4 107 104 0 0 353 R7VTT2 Pleckstrin OS=Columba livia GN=A306_03891 PE=4 SV=1
50 : U3INN0_ANAPL 0.87 0.97 2 105 2 105 104 0 0 347 U3INN0 Uncharacterized protein (Fragment) OS=Anas platyrhynchos GN=PLEK PE=4 SV=1
51 : H0YVX9_TAEGU 0.86 0.95 2 105 4 107 104 0 0 353 H0YVX9 Uncharacterized protein OS=Taeniopygia guttata GN=PLEK PE=4 SV=1
52 : L8IPE2_9CETA 0.85 0.90 1 105 3 107 105 0 0 352 L8IPE2 Pleckstrin (Fragment) OS=Bos mutus GN=M91_09588 PE=4 SV=1
53 : U3KGU4_FICAL 0.85 0.95 2 105 4 107 104 0 0 353 U3KGU4 Uncharacterized protein OS=Ficedula albicollis GN=PLEK PE=4 SV=1
54 : I3MNC6_SPETR 0.84 0.94 14 112 1 99 99 0 0 337 I3MNC6 Uncharacterized protein (Fragment) OS=Spermophilus tridecemlineatus GN=PLEK PE=4 SV=1
55 : V8P3Z9_OPHHA 0.83 0.96 2 105 8 111 104 0 0 317 V8P3Z9 Pleckstrin OS=Ophiophagus hannah GN=PLEK PE=4 SV=1
56 : G1MZ14_MELGA 0.82 0.95 2 112 37 147 111 0 0 388 G1MZ14 Uncharacterized protein OS=Meleagris gallopavo GN=PLEK PE=4 SV=2
57 : G1K8Y6_ANOCA 0.80 0.92 2 112 9 119 111 0 0 358 G1K8Y6 Uncharacterized protein OS=Anolis carolinensis GN=PLEK PE=4 SV=2
58 : M7BLM9_CHEMY 0.79 0.94 14 112 1 99 99 0 0 338 M7BLM9 Pleckstrin (Fragment) OS=Chelonia mydas GN=UY3_09917 PE=4 SV=1
59 : R0KVM0_ANAPL 0.77 0.93 11 112 1 102 102 0 0 341 R0KVM0 Pleckstrin (Fragment) OS=Anas platyrhynchos GN=Anapl_15340 PE=4 SV=1
60 : Q6PCH2_XENLA 0.76 0.88 2 104 4 105 103 1 1 289 Q6PCH2 MGC69065 protein OS=Xenopus laevis GN=plek PE=2 SV=1
61 : H2TVZ6_TAKRU 0.73 0.92 1 105 20 124 105 0 0 309 H2TVZ6 Uncharacterized protein (Fragment) OS=Takifugu rubripes GN=LOC101061631 PE=4 SV=1
62 : A0F039_PSEMX 0.70 0.91 1 105 1 105 105 0 0 158 A0F039 Pleckstrin (Fragment) OS=Psetta maxima PE=2 SV=1
63 : W5L6G9_ASTMX 0.70 0.88 1 112 3 114 112 0 0 355 W5L6G9 Uncharacterized protein (Fragment) OS=Astyanax mexicanus PE=4 SV=1
64 : W5NGG4_LEPOC 0.70 0.89 1 112 2 113 112 0 0 353 W5NGG4 Uncharacterized protein (Fragment) OS=Lepisosteus oculatus PE=4 SV=1
65 : H2TVZ7_TAKRU 0.69 0.88 1 112 1 112 112 0 0 352 H2TVZ7 Uncharacterized protein OS=Takifugu rubripes GN=LOC101061631 PE=4 SV=1
66 : L7N335_XENTR 0.69 0.87 2 112 4 114 111 0 0 351 L7N335 Uncharacterized protein OS=Xenopus tropicalis GN=plek PE=4 SV=1
67 : H3CT79_TETNG 0.67 0.88 1 112 3 114 112 0 0 354 H3CT79 Uncharacterized protein (Fragment) OS=Tetraodon nigroviridis PE=4 SV=1
68 : Q4SL65_TETNG 0.67 0.88 1 112 1 112 112 0 0 352 Q4SL65 Chromosome 17 SCAF14563, whole genome shotgun sequence OS=Tetraodon nigroviridis GN=GSTENG00016394001 PE=4 SV=1
69 : H3B8W1_LATCH 0.66 0.89 2 112 4 114 111 0 0 353 H3B8W1 Uncharacterized protein OS=Latimeria chalumnae GN=PLEK PE=4 SV=2
70 : K4FU54_CALMI 0.66 0.85 1 112 3 114 112 0 0 355 K4FU54 Pleckstrin-like protein OS=Callorhynchus milii PE=2 SV=1
71 : Q5BL93_XENTR 0.66 0.85 2 112 4 113 111 1 1 350 Q5BL93 Pleckstrin OS=Xenopus tropicalis GN=plek PE=2 SV=1
72 : W5ULW2_ICTPU 0.65 0.87 1 112 1 112 112 0 0 352 W5ULW2 Pleckstrin OS=Ictalurus punctatus GN=PLEK PE=2 SV=1
73 : E3TCC7_9TELE 0.64 0.85 1 112 1 112 112 0 0 329 E3TCC7 Pleckstrin OS=Ictalurus furcatus GN=PLEK PE=2 SV=1
74 : G3P376_GASAC 0.64 0.87 1 112 1 112 112 0 0 351 G3P376 Uncharacterized protein OS=Gasterosteus aculeatus PE=4 SV=1
75 : H2LPN1_ORYLA 0.64 0.85 1 112 16 127 112 0 0 305 H2LPN1 Uncharacterized protein (Fragment) OS=Oryzias latipes GN=LOC101172756 PE=4 SV=1
76 : H2LPN3_ORYLA 0.64 0.85 1 112 3 114 112 0 0 352 H2LPN3 Uncharacterized protein (Fragment) OS=Oryzias latipes GN=LOC101172756 PE=4 SV=1
77 : I3IV06_ORENI 0.64 0.87 1 112 1 112 112 0 0 351 I3IV06 Uncharacterized protein OS=Oreochromis niloticus GN=LOC100694733 PE=4 SV=1
78 : B5X5Z5_SALSA 0.63 0.88 1 112 30 141 112 0 0 381 B5X5Z5 Pleckstrin OS=Salmo salar GN=PLEK PE=2 SV=1
79 : C0PUM8_SALSA 0.63 0.89 2 112 1 111 111 0 0 351 C0PUM8 Pleckstrin (Fragment) OS=Salmo salar GN=PLEK PE=2 SV=1
80 : Q6P7E2_DANRE 0.63 0.87 1 112 1 112 112 0 0 352 Q6P7E2 Pleckstrin OS=Danio rerio GN=plek PE=2 SV=1
81 : F1QFB1_DANRE 0.62 0.85 1 112 1 114 114 1 2 354 F1QFB1 Uncharacterized protein OS=Danio rerio GN=plek PE=4 SV=1
82 : M4A880_XIPMA 0.62 0.84 1 112 1 112 112 0 0 351 M4A880 Uncharacterized protein OS=Xiphophorus maculatus PE=4 SV=1
83 : Q90W72_ONCMY 0.62 0.88 1 112 1 112 112 0 0 352 Q90W72 Pleckstrin OS=Oncorhynchus mykiss PE=2 SV=1
84 : H9GAS8_ANOCA 0.43 0.66 7 101 9 106 98 2 3 355 H9GAS8 Uncharacterized protein OS=Anolis carolinensis GN=PLEK2 PE=4 SV=2
85 : S4RJF4_PETMA 0.43 0.68 17 104 15 101 88 1 1 155 S4RJF4 Uncharacterized protein (Fragment) OS=Petromyzon marinus PE=4 SV=1
86 : E1BT20_CHICK 0.41 0.64 7 101 12 109 98 2 3 358 E1BT20 Uncharacterized protein (Fragment) OS=Gallus gallus GN=PLEK2 PE=4 SV=2
87 : G1NHB4_MELGA 0.41 0.64 7 101 9 106 98 2 3 347 G1NHB4 Uncharacterized protein OS=Meleagris gallopavo GN=PLEK2 PE=4 SV=2
88 : U3J560_ANAPL 0.41 0.65 6 101 1 99 99 2 3 308 U3J560 Uncharacterized protein (Fragment) OS=Anas platyrhynchos GN=PLEK2 PE=4 SV=1
89 : H0ZMR8_TAEGU 0.40 0.63 2 101 4 106 103 2 3 355 H0ZMR8 Uncharacterized protein OS=Taeniopygia guttata GN=PLEK2 PE=4 SV=1
90 : U3JRP2_FICAL 0.40 0.63 2 101 4 106 103 2 3 355 U3JRP2 Uncharacterized protein OS=Ficedula albicollis GN=PLEK2 PE=4 SV=1
91 : H3AS09_LATCH 0.39 0.65 7 110 9 115 107 2 3 353 H3AS09 Uncharacterized protein OS=Latimeria chalumnae PE=4 SV=1
92 : G3PF60_GASAC 0.38 0.63 6 107 10 114 105 2 3 358 G3PF60 Uncharacterized protein OS=Gasterosteus aculeatus PE=4 SV=1
93 : G3PF63_GASAC 0.38 0.63 6 107 8 112 105 2 3 360 G3PF63 Uncharacterized protein (Fragment) OS=Gasterosteus aculeatus PE=4 SV=1
94 : A7SVA1_NEMVE 0.37 0.64 1 108 4 111 108 0 0 390 A7SVA1 Predicted protein OS=Nematostella vectensis GN=v1g237545 PE=4 SV=1
95 : F6UII2_CALJA 0.37 0.61 1 107 1 110 110 1 3 353 F6UII2 Pleckstrin-2 OS=Callithrix jacchus GN=PLEK2 PE=2 SV=1
96 : F6UIR2_CALJA 0.37 0.61 1 107 1 110 110 1 3 357 F6UIR2 Uncharacterized protein OS=Callithrix jacchus GN=PLEK2 PE=4 SV=1
97 : M4AJU0_XIPMA 0.37 0.61 2 107 6 114 109 2 3 358 M4AJU0 Uncharacterized protein OS=Xiphophorus maculatus PE=4 SV=1
98 : W4XJC5_STRPU 0.37 0.64 2 100 4 103 103 5 7 375 W4XJC5 Uncharacterized protein OS=Strongylocentrotus purpuratus GN=Sp-Plek PE=4 SV=1
99 : F6R8Z7_MONDO 0.36 0.59 2 107 4 112 109 2 3 355 F6R8Z7 Uncharacterized protein OS=Monodelphis domestica GN=PLEK2 PE=4 SV=2
100 : F7D3I6_ORNAN 0.36 0.56 11 107 1 100 100 2 3 305 F7D3I6 Uncharacterized protein (Fragment) OS=Ornithorhynchus anatinus GN=PLEK2 PE=4 SV=1
101 : H2SLS3_TAKRU 0.36 0.61 6 101 9 107 99 2 3 350 H2SLS3 Uncharacterized protein OS=Takifugu rubripes GN=LOC101072073 PE=4 SV=1
102 : Q4RH22_TETNG 0.36 0.58 2 101 6 108 103 2 3 358 Q4RH22 Chromosome 10 SCAF15073, whole genome shotgun sequence OS=Tetraodon nigroviridis GN=GSTENG00034553001 PE=4 SV=1
103 : A6QLP8_BOVIN 0.35 0.60 1 107 1 110 110 1 3 353 A6QLP8 PLEK2 protein OS=Bos taurus GN=PLEK2 PE=2 SV=1
104 : D4ACD5_RAT 0.35 0.60 1 107 1 110 110 1 3 353 D4ACD5 Pleckstrin 2 (Predicted), isoform CRA_b OS=Rattus norvegicus GN=Plek2 PE=4 SV=1
105 : E9CEE7_CAPO3 0.35 0.60 6 100 338 432 95 0 0 702 E9CEE7 Uncharacterized protein OS=Capsaspora owczarzaki (strain ATCC 30864) GN=CAOG_06565 PE=4 SV=1
106 : F1SA39_PIG 0.35 0.60 1 107 1 110 110 1 3 353 F1SA39 Uncharacterized protein OS=Sus scrofa GN=PLEK2 PE=4 SV=1
107 : F7EFD3_MACMU 0.35 0.60 1 107 1 110 110 1 3 353 F7EFD3 Uncharacterized protein OS=Macaca mulatta GN=PLEK2 PE=4 SV=1
108 : G1QIR8_NOMLE 0.35 0.60 1 107 1 110 110 1 3 353 G1QIR8 Uncharacterized protein OS=Nomascus leucogenys GN=PLEK2 PE=4 SV=1
109 : G1T2H1_RABIT 0.35 0.60 1 107 1 110 110 1 3 353 G1T2H1 Uncharacterized protein OS=Oryctolagus cuniculus GN=PLEK2 PE=4 SV=1
110 : G3QIC2_GORGO 0.35 0.60 1 107 1 110 110 1 3 354 G3QIC2 Uncharacterized protein OS=Gorilla gorilla gorilla GN=101130095 PE=4 SV=1
111 : G3S734_GORGO 0.35 0.60 1 107 1 110 110 1 3 353 G3S734 Uncharacterized protein OS=Gorilla gorilla gorilla GN=101130095 PE=4 SV=1
112 : H0V0K6_CAVPO 0.35 0.60 1 107 1 110 110 1 3 353 H0V0K6 Uncharacterized protein OS=Cavia porcellus GN=PLEK2 PE=4 SV=1
113 : H2NLK2_PONAB 0.35 0.60 1 107 1 110 110 1 3 353 H2NLK2 Uncharacterized protein OS=Pongo abelii GN=PLEK2 PE=4 SV=1
114 : H2Q8H5_PANTR 0.35 0.59 1 107 1 110 110 1 3 353 H2Q8H5 Pleckstrin 2 OS=Pan troglodytes GN=PLEK2 PE=2 SV=1
115 : I3KUA2_ORENI 0.35 0.61 2 107 6 114 109 2 3 358 I3KUA2 Uncharacterized protein OS=Oreochromis niloticus GN=LOC100710313 PE=4 SV=1
116 : I3LYU1_SPETR 0.35 0.59 1 107 1 110 110 1 3 353 I3LYU1 Uncharacterized protein OS=Spermophilus tridecemlineatus GN=PLEK2 PE=4 SV=1
117 : K7D5Y0_PANTR 0.35 0.59 1 107 1 110 110 1 3 353 K7D5Y0 Pleckstrin 2 OS=Pan troglodytes GN=PLEK2 PE=2 SV=1
118 : L9JBY8_TUPCH 0.35 0.60 1 107 246 355 110 1 3 630 L9JBY8 Pleckstrin-2 OS=Tupaia chinensis GN=TREES_T100011057 PE=4 SV=1
119 : M3Y6R6_MUSPF 0.35 0.60 1 107 1 110 110 1 3 353 M3Y6R6 Uncharacterized protein OS=Mustela putorius furo GN=PLEK2 PE=4 SV=1
120 : PLEK2_HUMAN 0.35 0.60 1 107 1 110 110 1 3 353 Q9NYT0 Pleckstrin-2 OS=Homo sapiens GN=PLEK2 PE=1 SV=1
121 : U6CWE6_NEOVI 0.35 0.60 1 107 1 110 110 1 3 353 U6CWE6 Pleckstrin-2 OS=Neovison vison GN=PLEK2 PE=2 SV=1
122 : W5N9Z6_LEPOC 0.35 0.56 2 107 7 115 109 2 3 357 W5N9Z6 Uncharacterized protein OS=Lepisosteus oculatus PE=4 SV=1
123 : W5QJ51_SHEEP 0.35 0.61 1 107 1 110 110 1 3 353 W5QJ51 Uncharacterized protein OS=Ovis aries GN=PLEK2 PE=4 SV=1
124 : G7PAK5_MACFA 0.34 0.61 6 107 2 106 105 1 3 349 G7PAK5 Putative uncharacterized protein (Fragment) OS=Macaca fascicularis GN=EGM_16747 PE=4 SV=1
125 : H0YJD0_HUMAN 0.34 0.60 17 101 1 88 88 1 3 127 H0YJD0 Pleckstrin-2 (Fragment) OS=Homo sapiens GN=PLEK2 PE=2 SV=1
126 : H2M1C7_ORYLA 0.34 0.59 6 107 8 111 105 3 4 357 H2M1C7 Uncharacterized protein OS=Oryzias latipes GN=LOC101171538 PE=4 SV=1
127 : PLEK2_MOUSE 0.34 0.60 1 107 1 110 110 1 3 353 Q9WV52 Pleckstrin-2 OS=Mus musculus GN=Plek2 PE=1 SV=1
128 : B0EL61_ENTDS 0.33 0.64 7 105 23 119 100 2 4 390 B0EL61 Pleckstrin, putative OS=Entamoeba dispar (strain ATCC PRA-260 / SAW760) GN=EDI_206970 PE=4 SV=1
129 : C4LYX6_ENTHI 0.33 0.64 7 105 50 146 100 2 4 417 C4LYX6 Pleckstrin homology (PH) domain containing protein OS=Entamoeba histolytica GN=EHI_117920 PE=4 SV=1
130 : F6UH91_HORSE 0.33 0.56 1 107 1 110 110 1 3 353 F6UH91 Uncharacterized protein OS=Equus caballus GN=PLEK2 PE=4 SV=1
131 : G1P2F9_MYOLU 0.33 0.57 13 107 17 114 98 1 3 357 G1P2F9 Uncharacterized protein (Fragment) OS=Myotis lucifugus GN=PLEK2 PE=4 SV=1
132 : G3TBA1_LOXAF 0.33 0.58 2 107 2 110 109 1 3 353 G3TBA1 Uncharacterized protein (Fragment) OS=Loxodonta africana GN=PLEK2 PE=4 SV=1
133 : K2G469_ENTNP 0.33 0.64 7 105 23 119 100 2 4 390 K2G469 Pleckstrin (PH) domain containing family protein OS=Entamoeba nuttalli (strain P19) GN=ENU1_210470 PE=4 SV=1
134 : M2RW70_ENTHI 0.33 0.64 7 105 50 146 100 2 4 417 M2RW70 Pleckstrin (PH) domain protein OS=Entamoeba histolytica KU27 GN=EHI5A_002640 PE=4 SV=1
135 : M3UIS8_ENTHI 0.33 0.64 7 105 50 146 100 2 4 417 M3UIS8 Pleckstrin domain containing family protein OS=Entamoeba histolytica HM-1:IMSS-B GN=EHI8A_000650 PE=4 SV=1
136 : M7WCQ7_ENTHI 0.33 0.64 7 105 50 146 100 2 4 417 M7WCQ7 Pleckstrin (PH) domain containing family protein OS=Entamoeba histolytica HM-3:IMSS GN=KM1_003510 PE=4 SV=1
137 : N9URV3_ENTHI 0.33 0.64 7 105 50 146 100 2 4 417 N9URV3 Pleckstrin (PH) domain containing family protein OS=Entamoeba histolytica HM-1:IMSS-A GN=EHI7A_000650 PE=4 SV=1
138 : S0AXI1_ENTHI 0.33 0.64 7 105 23 119 100 2 4 390 S0AXI1 Pleckstrin homology (PH) domain containing protein OS=Entamoeba histolytica PE=2 SV=1
139 : S0AZJ1_ENTHI 0.33 0.64 7 105 23 119 100 2 4 390 S0AZJ1 Pleckstrin homology (PH) domain containing protein OS=Entamoeba histolytica PE=2 SV=1
140 : S7NCX9_MYOBR 0.33 0.59 14 107 21 117 97 1 3 360 S7NCX9 Pleckstrin-2 OS=Myotis brandtii GN=D623_10024691 PE=4 SV=1
141 : B3DLH5_DANRE 0.32 0.60 2 101 7 109 103 2 3 361 B3DLH5 Plek2 protein OS=Danio rerio GN=plek2 PE=2 SV=1
142 : D2HRG7_AILME 0.32 0.58 14 107 1 97 97 1 3 299 D2HRG7 Putative uncharacterized protein (Fragment) OS=Ailuropoda melanoleuca GN=PANDA_014586 PE=4 SV=1
143 : D8LF66_ECTSI 0.32 0.48 8 101 12 101 95 4 6 532 D8LF66 Putative uncharacterized protein OS=Ectocarpus siliculosus GN=Esi_0141_0059 PE=4 SV=1
144 : F6X9S9_CANFA 0.32 0.58 14 107 1 97 97 1 3 340 F6X9S9 Uncharacterized protein (Fragment) OS=Canis familiaris GN=PLEK2 PE=4 SV=1
145 : G1LNK0_AILME 0.32 0.57 15 107 17 112 96 1 3 360 G1LNK0 Uncharacterized protein (Fragment) OS=Ailuropoda melanoleuca GN=PLEK2 PE=4 SV=1
146 : G1NVY7_MYOLU 0.32 0.51 9 103 63 161 100 4 6 1043 G1NVY7 Uncharacterized protein OS=Myotis lucifugus GN=PLEKHA7 PE=4 SV=1
147 : G9KH43_MUSPF 0.32 0.57 15 107 1 96 96 1 3 339 G9KH43 Pleckstrin 2 (Fragment) OS=Mustela putorius furo PE=2 SV=1
148 : I1FJL8_AMPQE 0.32 0.57 6 107 19 120 103 2 2 357 I1FJL8 Uncharacterized protein OS=Amphimedon queenslandica GN=LOC100639031 PE=4 SV=1
149 : L8HJZ7_9CETA 0.32 0.58 14 107 1 97 97 1 3 340 L8HJZ7 Pleckstrin-2 (Fragment) OS=Bos mutus GN=M91_06010 PE=4 SV=1
150 : S0B615_ENTIV 0.32 0.64 8 108 24 122 102 2 4 404 S0B615 Pleckstrin, putative OS=Entamoeba invadens PE=2 SV=1
151 : T1JA48_STRMM 0.32 0.46 3 102 1626 1725 102 4 4 1852 T1JA48 Uncharacterized protein OS=Strigamia maritima PE=4 SV=1
152 : A0DTZ0_PARTE 0.31 0.54 8 100 15 107 94 2 2 121 A0DTZ0 Chromosome undetermined scaffold_63, whole genome shotgun sequence OS=Paramecium tetraurelia GN=GSPATT00020191001 PE=4 SV=1
153 : A7SSW6_NEMVE 0.31 0.54 6 101 11 108 99 3 4 211 A7SSW6 Predicted protein OS=Nematostella vectensis GN=v1g247210 PE=4 SV=1
154 : C3ZU12_BRAFL 0.31 0.50 1 99 1967 2066 102 4 5 2087 C3ZU12 Putative uncharacterized protein OS=Branchiostoma floridae GN=BRAFLDRAFT_87274 PE=4 SV=1
155 : C5FH13_ARTOC 0.31 0.54 1 97 84 175 99 5 9 574 C5FH13 Immunogenic protein OS=Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) GN=MCYG_01462 PE=4 SV=1
156 : E0VWI8_PEDHC 0.31 0.49 8 100 7 99 98 5 10 753 E0VWI8 Oxysterol-binding protein OS=Pediculus humanus subsp. corporis GN=Phum_PHUM486740 PE=3 SV=1
157 : E2BXI0_HARSA 0.31 0.54 10 101 437 528 95 4 6 542 E2BXI0 FERM, RhoGEF and pleckstrin domain-containing protein 1 OS=Harpegnathos saltator GN=EAI_00831 PE=4 SV=1
158 : F0Z8N8_DICPU 0.31 0.57 6 101 1 95 97 3 3 252 F0Z8N8 Putative uncharacterized protein (Fragment) OS=Dictyostelium purpureum GN=DICPUDRAFT_26502 PE=4 SV=1
159 : F0ZH73_DICPU 0.31 0.48 3 101 1206 1307 108 7 15 1308 F0ZH73 Putative uncharacterized protein OS=Dictyostelium purpureum GN=DICPUDRAFT_46997 PE=4 SV=1
160 : F7AT12_CIOIN 0.31 0.52 9 113 905 1009 108 4 6 1011 F7AT12 Uncharacterized protein OS=Ciona intestinalis GN=Cin.44879 PE=4 SV=2
161 : F7ATH6_CIOIN 0.31 0.52 9 111 894 996 106 4 6 996 F7ATH6 Uncharacterized protein OS=Ciona intestinalis GN=Cin.44879 PE=4 SV=2
162 : G3H1M2_CRIGR 0.31 0.57 15 107 1 96 96 1 3 339 G3H1M2 Pleckstrin-2 (Fragment) OS=Cricetulus griseus GN=I79_004071 PE=4 SV=1
163 : G3U5I0_LOXAF 0.31 0.56 14 107 1 97 97 1 3 344 G3U5I0 Uncharacterized protein (Fragment) OS=Loxodonta africana GN=PLEK2 PE=4 SV=1
164 : G3UE32_LOXAF 0.31 0.51 9 103 63 161 100 4 6 1170 G3UE32 Uncharacterized protein OS=Loxodonta africana GN=PLEKHA7 PE=4 SV=1
165 : H0WB04_CAVPO 0.31 0.49 8 101 19 118 100 4 6 269 H0WB04 Uncharacterized protein (Fragment) OS=Cavia porcellus GN=SKAP1 PE=4 SV=1
166 : H0XRY3_OTOGA 0.31 0.57 2 107 2 110 109 1 3 357 H0XRY3 Uncharacterized protein (Fragment) OS=Otolemur garnettii GN=PLEK2 PE=4 SV=1
167 : I1FWT5_AMPQE 0.31 0.59 9 101 24 114 93 1 2 173 I1FWT5 Uncharacterized protein OS=Amphimedon queenslandica GN=LOC100631695 PE=4 SV=1
168 : L8GW48_ACACA 0.31 0.52 7 105 30 130 103 3 6 504 L8GW48 PAKA subfamily protein kinase OS=Acanthamoeba castellanii str. Neff GN=ACA1_383610 PE=4 SV=1
169 : L8GXG1_ACACA 0.31 0.56 7 99 67 160 95 3 3 169 L8GXG1 PH domain containing protein OS=Acanthamoeba castellanii str. Neff GN=ACA1_063760 PE=4 SV=1
170 : M1ESQ2_MUSPF 0.31 0.54 10 99 74 163 91 2 2 163 M1ESQ2 FERM, RhoGEF and pleckstrin domain protein 2 (Fragment) OS=Mustela putorius furo PE=2 SV=1
171 : M3WEF6_FELCA 0.31 0.56 8 107 9 112 104 2 4 359 M3WEF6 Uncharacterized protein (Fragment) OS=Felis catus GN=PLEK2 PE=4 SV=1
172 : Q559C4_DICDI 0.31 0.55 2 101 11 109 101 3 3 264 Q559C4 Uncharacterized protein OS=Dictyostelium discoideum GN=DDB_0217064 PE=4 SV=1
173 : Q6BFS9_PARTE 0.31 0.51 7 100 14 107 95 2 2 122 Q6BFS9 Chromosome undetermined scaffold_1, whole genome shotgun sequence OS=Paramecium tetraurelia GN=GSPATT00000209001 PE=4 SV=1
174 : W4XIF6_STRPU 0.31 0.54 6 100 283 378 97 3 3 408 W4XIF6 Uncharacterized protein OS=Strongylocentrotus purpuratus GN=Sp-Plekha1 PE=4 SV=1
175 : A0E1S3_PARTE 0.30 0.54 8 100 15 107 94 2 2 121 A0E1S3 Chromosome undetermined scaffold_73, whole genome shotgun sequence OS=Paramecium tetraurelia GN=GSPATT00022411001 PE=4 SV=1
176 : E6R1T8_CRYGW 0.30 0.47 6 100 440 529 99 6 13 1583 E6R1T8 UDP-glucose:sterol glucosyltransferase, putative OS=Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071) GN=CGB_C6610C PE=4 SV=1
177 : E6ZH03_DICLA 0.30 0.48 9 99 51 143 93 2 2 185 E6ZH03 Pleckstrin homology domain-containing family A member 7 OS=Dicentrarchus labrax GN=PLEKHA7 PE=4 SV=1
178 : F7BE41_CIOIN 0.30 0.55 2 108 4 110 107 0 0 360 F7BE41 Uncharacterized protein OS=Ciona intestinalis PE=4 SV=2
179 : G3W7Z5_SARHA 0.30 0.52 4 107 6 114 109 3 5 357 G3W7Z5 Uncharacterized protein (Fragment) OS=Sarcophilus harrisii GN=PLEK2 PE=4 SV=1
180 : H6BD22_OSTED 0.30 0.49 8 97 37 125 92 2 5 143 H6BD22 Dapp1 dual adaptor for phosphotirosine (Fragment) OS=Ostrea edulis PE=2 SV=1
181 : Q00Y38_OSTTA 0.30 0.52 7 100 218 314 99 5 7 327 Q00Y38 AtPH1-like protein (ISS) OS=Ostreococcus tauri GN=Ot12g01220 PE=4 SV=1
182 : Q17LI3_AEDAE 0.30 0.57 9 101 475 567 96 4 6 599 Q17LI3 AAEL001353-PA (Fragment) OS=Aedes aegypti GN=AAEL001353 PE=4 SV=1
183 : Q54R43_DICDI 0.30 0.58 3 101 137 234 100 2 3 245 Q54R43 Putative uncharacterized protein OS=Dictyostelium discoideum GN=DDB_0185494 PE=4 SV=1
184 : Q7PX94_ANOGA 0.30 0.57 9 105 1056 1152 100 4 6 1172 Q7PX94 AGAP001287-PA OS=Anopheles gambiae GN=AgaP_AGAP001287 PE=4 SV=5
185 : S8CQI8_9LAMI 0.30 0.51 7 100 28 123 97 3 4 142 S8CQI8 Uncharacterized protein (Fragment) OS=Genlisea aurea GN=M569_05768 PE=4 SV=1
186 : T1EB44_ANOAQ 0.30 0.57 9 105 462 558 100 4 6 575 T1EB44 Putative rho guanine nucleotide exchange factor cdep (Fragment) OS=Anopheles aquasalis PE=2 SV=1
187 : W4G0M6_9STRA 0.30 0.51 8 98 63 162 100 3 9 714 W4G0M6 AGC protein kinase, variant OS=Aphanomyces astaci GN=H257_11802 PE=4 SV=1
188 : W4G1V9_9STRA 0.30 0.51 8 98 63 162 100 3 9 783 W4G1V9 AGC protein kinase OS=Aphanomyces astaci GN=H257_11802 PE=4 SV=1
## ALIGNMENTS 1 - 70
SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
1 1 A M 0 0 235 83 3 MMMMMMMMMMMMMMMMMMMM MMMMMMMMMMMMMM M M M L MMMMM MM L
2 2 A E + 0 0 168 113 13 EEEEEEEEEEEEEEEEEEEE EEEEEEEEEEEEEEE E EEE EEEEEEEE EEE EEEEEEEEEEE
3 3 A P + 0 0 64 116 66 PPPPPPPPPPPPPPPPPPPP PPPPPPPPPPPPPPP P PPQ PPPPPPNP PPP PPPPPPPPPPP
4 4 A K + 0 0 169 117 80 KKKKKKKKKKKKKKKKKKKK KKKKKKKKKKKKKKQ K KMR KMKMMMIM RMR QQQSKQQEEKR
5 5 A R - 0 0 62 117 93 RRRRRRRRRRRRRRRRRRRR RRRRRRRRRRRRKKE R RRR RRRRRRLR RRL KEETQEKEEKV
6 6 A I S S- 0 0 71 130 36 IIIIIIIIIIIIIIIIIIII IIIIIIIIIIIIIIM I IICVIIVIIITI III IIIIIIIIIII
7 7 A R E S+A 28 0A 91 148 39 RRRRRRRRRRRRRRRRRRRR RRRRRRRRRRRRRRR R RRHQRRRRRRRR RRR RRRRRRRRRRR
8 8 A E E +A 27 0A 51 158 21 EEEEEEEEEEEEEEEEEEEE EEEEEEEEEEEEEEE E EEKEEEEEEEIE EEE EEEEEEEEEEE
9 9 A G E -A 26 0A 5 167 7 GGGGGGGGGGGGGGGGGGGG GGGGGGGGGGGGGGG G GGTFGGGGGGFG GGG GGGGGGGGGGG
10 10 A Y E +A 25 0A 136 169 22 YYYYYYYYYYYYYYYYYYYY YYYYYYYYYYYYYYC Y YYFYYYYYYYLY YYY YYYYYYYYYYY
11 11 A L E -A 24 0A 2 170 9 LLLLLLLLLLLLLLLLLLLL LLLLLLLLLLLLLLR L LLLLLLLLLLLL LLL LLLLLLLLLLLL
12 12 A V E -AB 23 82A 16 171 45 VVVVVVVVVVVVVVVVVVVV VVVVVVVVVVVVVVK V VVKQVVVVVVAV VVV LVVVVVVVVVVV
13 13 A K E -AB 22 81A 12 172 17 KKKKKKKKKKKKKKKKKKKK KKKKKKKKKKKKKKF K KKPQKKKKKKSK KKK MKKKKKKKKKKK
14 14 A K E + B 0 80A 14 179 46 KKKKRKRRKKRRKKKKKKRR RRRRRKKRKKRRKKK K KKTKKKKKKKQKQKKKQQKKKKKKKKKKK
15 15 A G S S+ 0 0 20 183 30 GGGGGGGGGGGGGGGGGGGGGG GGGGGGGGGGGGGGG G GGGGGGGGGGGGGGGGGG.GGGGGGGGNR
16 16 A S S S+ 0 0 82 176 85 SSSSSSSSSSSSSSSSSSSSSS SSSSSSSSSSSSSSS N NSSSSSSSSSSSSSSSSSVTTTTTATTST
17 17 A V S S- 0 0 82 180 55 VVVVVVVMVVVMVVVVVVVMVMVVVVMMMMVVMVMVVV V VMMVMMMMMMMMVMMMMMMVVVVVMLLVV
18 18 A F S S- 0 0 193 187 70 FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF F FFFFFFFFFFFFFFFFFFFLLLFLFLLFF
19 19 A N S S+ 0 0 129 187 59 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN N NNNNNNNNNNNKNNNNNNNNNNNNNNNNS
20 20 A T - 0 0 54 184 69 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTSTSSST T TTTSTTTTTTSTTTTTTTKTSSSTKSSSS
21 21 A W + 0 0 55 186 2 WWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWW W WWWWWWWWWWWWWWWWWWWWWWWWWWWWW
22 22 A K E -A 13 0A 136 187 26 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK K KKKKKKKKKKKKKKKKKKTKKKKKKKKKK
23 23 A P E +A 12 0A 88 187 76 PPPPPPPPPPPPPPPPPPAPPPPPPPPPPPPPPPPPPP P PPPPPPAPPPPPAPPPPPPPAAVPPPPAA
24 24 A M E -A 11 0A 15 189 67 MMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMVVVMVMVVMT
25 25 A W E +AC 10 36A 29 189 2 WWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWW
26 26 A V E -AC 9 35A 0 189 57 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVMVVVVVVVVVVVVVVVVVVVVVVVVVVIV
27 27 A V E -AC 8 34A 0 189 20 VVVVVVVVVVVVVVVVVVVVVVVVVVVVIIVVVVVVVVVVVVVVVVVVVVVVVVVVVVVTVVVVVTVVVV
28 28 A L E -AC 7 33A 0 189 5 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
29 29 A L E > - C 0 32A 14 189 94 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLSLSLLLSSASSLSSLL
30 30 A E T 3 S+ 0 0 128 189 54 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDEEEEEEEEEEEDEEEEDDEEEEEE
31 31 A D T 3 S- 0 0 111 189 55 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
32 32 A G E < -CD 29 49A 8 189 84 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAAGGGGGGGAGGGGGGGGGGGAGGGAGGGAGAAGE
33 33 A I E -CD 28 48A 0 189 29 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIVMIIVIVVVI
34 34 A E E -CD 27 47A 42 189 98 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEK
35 35 A F E +CD 26 46A 3 189 9 FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
36 36 A Y E -C 25 0A 25 189 2 YYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYFYFYYYYFYYYYYYYY
37 37 A K S S+ 0 0 122 189 23 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKD
38 38 A K S > S- 0 0 156 189 92 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKKKRKRRRKRKKRKKRKKRKKKKKKKK
39 39 A K T 3 S- 0 0 97 189 67 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
40 40 A S T 3 + 0 0 63 189 70 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSISSASASASTSTISTTTTSTNTTTI
41 41 A D < - 0 0 63 189 47 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
42 42 A N S S+ 0 0 146 186 76 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNSNNNNNNNNSNTNNNRRSSRNRRNQ
43 43 A S S S- 0 0 70 188 63 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSNSSSSSSSSSNSSSSSSSSSSSSNSSSSSSSSSSSSSSS
44 44 A P - 0 0 48 185 23 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP
45 45 A K S S- 0 0 99 189 41 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
46 46 A G E -D 35 0A 22 189 12 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
47 47 A M E -D 34 0A 110 189 83 MMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMV
48 48 A I E -D 33 0A 3 189 13 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIVVIIIIIIIIVIIIIIIIIIII
49 49 A P E -D 32 0A 34 189 84 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP
50 50 A L S S+ 0 0 7 189 4 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
51 51 A K S S+ 0 0 108 189 71 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
52 52 A G S S+ 0 0 33 189 29 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGDE
53 53 A S - 0 0 17 180 69 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSAAAAATAACS
54 54 A T - 0 0 68 184 63 TTTTTTTTTTTTTTTTTTTTTTTTTSTTTTTTATTTTTTVTITTTSTSSTSASTTTTSTVTATSTVTTSL
55 55 A L E -E 71 0A 47 186 57 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLVLVILLIILIIILILLILIIILLLFLILLIL
56 56 A T E -E 70 0A 31 187 61 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTNTTNNQNNHTHMTNTNNSLVTILSLLTT
57 57 A S S S+ 0 0 76 188 66 SSSSSSSSSSSSSSSSSSSSSSCSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSNSSSNSNSSSS
58 58 A P S S- 0 0 89 187 39 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPSPPPPPHPPPPPHPPPP
59 59 A C - 0 0 14 188 51 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
60 60 A Q - 0 0 120 189 81 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
61 61 A D S S+ 0 0 141 189 40 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDDDDDDDDDDDDDDDDEDDEE
62 62 A F S S- 0 0 72 189 70 FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFY
63 63 A G - 0 0 36 189 67 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGSGGGGGGGGGGGAAGGSGGGCNGGGGGAN
64 64 A K + 0 0 129 183 54 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
65 65 A R S S- 0 0 217 187 30 RRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRKRRRRRRRRRRRRRRRRRRRRRRRRRRRRRR
66 66 A M S S- 0 0 103 188 88 MMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMTMMMMTMMMTMLMMMLMLLMM
67 67 A F S S+ 0 0 50 188 48 FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFLLFLLFLLFF
68 68 A V E - F 0 82A 4 189 48 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVV
69 69 A F E - F 0 81A 1 189 29 FFFFFFFFFFFFFFLLLFFFFFFFFFFFFFFLFFFFFFLFLFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
70 70 A K E -EF 56 80A 30 188 18 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
71 71 A I E -EF 55 79A 0 161 37 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIILLIIIIILILFLLLLLILILLLLLLILLLILIILL
72 72 A T E - F 0 78A 30 177 83 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAATTTTTTTATTSTTTTTTTTTTTTTTSSTTTTSR
73 73 A T E >> - F 0 77A 1 178 41 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTSTSATTTAMAAVTVTTATTATTTMTTTTTTT
74 74 A T T 34 S+ 0 0 86 189 89 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTKTTTTTTTIATTAAPAAATATAANAATDDTPDADDAA
75 75 A K T 34 S- 0 0 151 189 74 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
76 76 A Q T <4 S+ 0 0 176 189 82 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHQLKKKKKLKKQN
77 77 A Q E < - F 0 73A 68 189 81 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQHQHHQQ
78 78 A D E - F 0 72A 58 188 60 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDNNAD
79 79 A H E - F 0 71A 1 188 63 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHQHQHHHHHHHHHHHHHHHHHHHHHHHHHHHH
80 80 A F E +BF 14 70A 27 189 43 FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFYFYFFFFFFFFFFFFIFFFFYFFFYFYFFYF
81 81 A F E -BF 13 69A 0 189 23 FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFL
82 82 A Q E -BF 12 68A 37 189 63 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
83 83 A A - 0 0 8 189 9 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
84 84 A A S S- 0 0 34 189 77 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAASAAAAAASSSSAASSSTTSSSSSS
85 85 A F S > S- 0 0 91 189 93 FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFYFFFYYFFYFYYFYYYYYYYFYFHYHYYHHHHHHHHHYH
86 86 A L H >> S+ 0 0 108 188 93 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLQVVLLVHVVLL
87 87 A E H 3> S+ 0 0 121 189 30 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDE
88 88 A E H 3> S+ 0 0 18 189 18 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDE
89 89 A R H < S+ 0 0 54 151 74 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHCHCCCCCCCCCCCCCCCCC
103 103 A I H >< S+ 0 0 43 150 84 IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIILLLIIIIII
104 104 A E T 3< S+ 0 0 97 148 51 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDEEEDEEDDEDELDLEDEQQQEQEQQAE
105 105 A G T < S+ 0 0 59 146 63 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG GGGGGNGGEA
106 106 A L < + 0 0 96 80 28 G G G GGGG GGGGGGGG
107 107 A E - 0 0 140 80 49 Q Q Q QQQQ KKKQKKQQ
108 108 A H + 0 0 162 35 54 K K K RRRR RKKRRRKK
109 109 A H - 0 0 183 32 8 F F F FFFF FFFFFFFF
110 110 A H - 0 0 171 32 47 A A A ASAA AAASAAAA
111 111 A H + 0 0 160 31 4 R R R RRRR RRRRRRRR
112 112 A H 0 0 183 30 21 K K K KRKK KKKKKKKK
113 113 A H 0 0 240 2 73
## ALIGNMENTS 71 - 140
SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....8....:....9....:....0....:....1....:....2....:....3....:....4
1 1 A M 0 0 235 83 3 MMMMMMM MMMM LMM MM MMMMMMMMM MMMMMM M M M
2 2 A E + 0 0 168 113 13 EEEEEEEEEEEEE EE SEEEGE EEE EEEEEEEEEQEEEEEEEE E E E
3 3 A P + 0 0 64 116 66 PPPPPPPPPPPPP AA RDDVQG TDD DDDDDDDNDVDDEDDDND D D G
4 4 A K + 0 0 169 117 80 QNNQQQQKKTTQK GG RGGPKG GGG GGGGGGGGGNGGGGGGAG G G G
5 5 A R - 0 0 62 117 93 KIIQEEEQQTTEQ VV KVVVIV VVV VVVVVVVVVIVLVVVVIV V V V
6 6 A I S S- 0 0 71 130 36 IIIIIIIIIIIII LLL LLILLILL LLLLLLLLLLLLLLLLLLLLLLLL LL L L
7 7 A R E S+A 28 0A 91 148 39 RRRRRRRKKRRRKK KKKKKKRRKKKRKK RRKKKKKKKKKKKKRKKKKKKKKK KKKKK KKKKKKKK
8 8 A E E +A 27 0A 51 158 21 EEVEEEEEEEEEEE EEEEEEEEEEEEDE EEEECEEEEEEEEEEEEEEEEEEE EEEEG EEEEEEEE
9 9 A G E -A 26 0A 5 167 7 GGGGGGGGGGGGGG GGGGGGGGGGGGGG GGGGGGGGGGGGGGGGGGGGGGGG GGGGG GGGGGGGG
10 10 A Y E +A 25 0A 136 169 22 YYYYYYFYYYYYYF FFFFFFFFYFFFFF FFFFFFFFFFFFFFFFFFFFFFFF FFYYL FYYYYYYY
11 11 A L E -A 24 0A 2 170 9 .LLLLLLLLLLLLL LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL LLLLP LLLLLLLL
12 12 A V E -AB 23 82A 16 171 45 LVVVVVVVVVVVVV VVVVVVVVVVVVVVAVVVVVVVVVVVVVVVVVVVVVVVV IVVVV VVVVVVVV
13 13 A K E -AB 22 81A 12 172 17 VKKKKKKKKKKKKK KKKKKKKKKKKKKKLKKKKKKKKKKKKKKKKKKKKKKKK KKKKKRKKKKKKKK
14 14 A K E + B 0 80A 14 179 46 KKKKKKKKKKKKKK RRRRRRRRKRRRKRKRRRRKRRRRRRRRRRRRRRRRRRR RRKKRSRKKKKKKKQ
15 15 A G S S+ 0 0 20 183 30 KGGGGGGGGGGGGG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG GGGGGGGGGGGGGGG
16 16 A S S S+ 0 0 82 176 85 ATTTTTTTTTTTTH HHHHHHHHHHHH.HHHHHHHHHHHHHHHHHHHHHHHHHH HHAAHHHAAAAAAAH
17 17 A V S S- 0 0 82 180 55 MVVLLLLVVVVVVVVIIVVVVLLVIII.ILLLIIIIIIIIIIIIVIILIIIIIIIVIDDIIIDDDDDDDI
18 18 A F S S- 0 0 193 187 70 FLLLLLLLLLLLLVVVVVVVVVVRVVVHVVVVVVRVVVVVVVVVVVVVVVVVVVVVVFFVVVFFFFFFFV
19 19 A N S S+ 0 0 129 187 59 NNNNNNNNNNnNNHHHHHRRHHHHHHHkHHHPHHHHHHHHHHHHHHHHHHHQHHHHHHHHHHHHHHHHHH
20 20 A T - 0 0 54 184 69 KSSSSSSSSSsSSNNNNNNNNNNNNNNnNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTNNNTTTTTTTN
21 21 A W + 0 0 55 186 2 WWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWW
22 22 A K E -A 13 0A 136 187 26 KKKKSSRKKKKSKKKKKKKKKKKKKKKRKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
23 23 A P E +A 12 0A 88 187 76 PVVAAAAVVAAAVAAVVVVVTAATVVATVVAAAAMVAAAAAAAVAVVVAAAVAAAAAKKVAVKKKKKKKA
24 24 A M E -A 11 0A 15 189 67 MVVVVVVVVVVVVRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRR
25 25 A W E +AC 10 36A 29 189 2 WWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWW
26 26 A V E -AC 9 35A 0 189 57 VVVVVVVVVVVVVFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
27 27 A V E -AC 8 34A 0 189 20 TVVVVVVMVVVVVVMVVVVVVVVVVVVVVVVVIIVIIIIIIIIIVIIVIIIVIIIVIVVIVIVVVVVVVV
28 28 A L E -AC 7 33A 0 189 5 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLMMLLLMMMMMMML
29 29 A L E > - C 0 32A 14 189 94 LAASSSSSSKKSSLDLLLLLFMMYRRTTRKTKRRHRRRRRRRRRTRRRRRRLRRRTRKKRRRKKKKKKKR
30 30 A E T 3 S+ 0 0 128 189 54 EDDDEEEEDDDEEQGQQQQQSSSDQQPEQQSSQQNQQQQQQQQQPQQQQQQPQQQPQDDQQQDDDDDDDQ
31 31 A D T 3 S- 0 0 111 189 55 DDDDDDDDDDDDDDEDDDDDDDDENNDDNNDDNNSNNNNNNNNNDNNNNNNDNNNDNQQNNNQQQQQQQN
32 32 A G E < -CD 29 49A 8 189 84 GGGGGGGGGAAGGRSKKKKKKKKKTTKSTTEKTTRTTTTTTTTTKTTTTTTRTTTKTYYTTMYYYYYYYT
33 33 A I E -CD 28 48A 0 189 29 IIILLLVMVIILVLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLIILLLIIIIIIIL
34 34 A E E -CD 27 47A 42 189 98 EEEEEEDEEEEDELTLLLLLMLLCVVLALLLLLLELVVLVVLVVLLVLLVLLLVVLLWWLLLWWWWWWWL
35 35 A F E +CD 26 46A 3 189 9 FFFFFFFFFFFYFYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYY
36 36 A Y E -C 25 0A 25 189 2 YYYYYYYFFFFYFYYYYYYYYYYFYYYYYFFFYYYYYYYYYYYYYYYYYYYYYYYFYFFYYYFFFFFFFY
37 37 A K S S+ 0 0 122 189 23 KKKKKKKKKKKKKKTKKKKKKKKKKKKKKKKKKKQKKKKKKKKKKKKKKKKKKKKKKPPKKKPPPPPPPK
38 38 A K S > S- 0 0 156 189 92 KKKKKKKRRKKKRICLLFIIPYYKLLYQLPYYFLTLLLLLLLLLYLLLLLLYFLLYLKKLLLKKKKKKKL
39 39 A K T 3 S- 0 0 97 189 67 KKKKKKKKKKKKKVKEEEEEVEEKEEETAEDEEEPEEEEEEEEEEEEQEEEDQEEEENNEEENNNNNNNE
40 40 A S T 3 + 0 0 63 189 70 NTTTIITTATTTTGGGGGGGGGGEGGGTGGGGGGTAGGGGGGGGGGGGGGGCGGGGGTTGGGTTTTTTTG
41 41 A D < - 0 0 63 189 47 DDDDDDDDDDDDDgEggggggggEgggDggssggDggggggggggggggggsgggggGGgggGGGGGGGg
42 42 A N S S+ 0 0 146 186 76 NSSRRRSNSRRHDeVeeeeedddTnnd.eeddttTnttttttttdatttttdtttdtSStntSSSSSSSn
43 43 A S S S- 0 0 70 188 63 SSSSSSSAANNSAsSsssppsssDPPsstvssPPEPPPPPPPPPsPPPPPPsPPPsPaaPPPaaaaaaaP
44 44 A P - 0 0 48 185 23 PPPPPPPPPAAPSpSppppptqqPPPqpppqqPPPPPPPPPPPPqPPPPPPlPPPqPppPPPpppppppP
45 45 A K S S- 0 0 99 189 41 KKKKKKKKKKKKKKKKKKKKKRRAKKRAKKRRKKVKKKKKKKKKRKKKKKKRKKKRKKKKKKKKKKKKKK
46 46 A G E -D 35 0A 22 189 12 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
47 47 A M E -D 34 0A 110 189 83 MMMMMMMMMMMMMRSRRRRRKKKWRRKVQQATRRVRRRRRRQRRKRRQRRRKRRRKRVVRQRVVVVVVVQ
48 48 A I E -D 33 0A 3 189 13 IIIIIIIIIIIIIIIIIIIIIIIVIIIIIIVIIIIIIIIIIIIIIIIIIIIVIIIIIIIIIIIIIIIIII
49 49 A P E -D 32 0A 34 189 84 PPPPPPPPPPPPPLPLLLLLLLLDLLLELLLLLVPLFLLLLLLLLLLLLLLLLFLLVEEVLLEEEEEEEL
50 50 A L S S+ 0 0 7 189 4 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
51 51 A K S S+ 0 0 108 189 71 KKKKKKKKKKKKKDKDDDDDDKKLDDKRDDKKDDDDDDDDDDDDKDDDDDDLDDDKDDDDDDDDDDDDDD
52 52 A G S S+ 0 0 33 189 29 GEEGGGGGGGGGGGDGGGGGGDDGGGDGGGGDGGGGGGGGGGGGDGGGGGGGGGGDGGGGGGGGGGGGGG
53 53 A S - 0 0 17 180 69 TAAAAAAAAAAAACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCNNCCCNNNNNNNC
54 54 A T - 0 0 68 184 63 VVVVKKTVVTTTVTQTTTTTKVVFTTLSTTRQTTRTTTTTTTTTVTTTTTTQTTTVTSSTTTSSSSSSST
55 55 A L E -E 71 0A 47 186 57 IMMLLLLLLLLLLIVIIIIIIIIIIIIVIIVIIIVIIIIIIIIIIIIIIIILIIIIISSIIISSSSSSSI
56 56 A T E -E 70 0A 31 187 61 STTVLLSTTTTITTVTTTTTTTTVTTTITTVITTDTTTTTTTTTTTTTTTTTTTTTTAATTIAAAAAAAT
57 57 A S S S+ 0 0 76 188 66 NNNNSSSSSSSSSCSCCCCCCCCSCCCSCCSCCCTCCCCCCCCCCCCCCCCCCCCCCVVCCCVVVVVVVC
58 58 A P S S- 0 0 89 187 39 HPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPHPPPPPPPPPPPPPPPPPPPPPPLLPPPLLLLLLLP
59 59 A C - 0 0 14 188 51 CCCCCCCCCCCCCCCCCCCCCFFCCCFCCCFFCCPCCCCCCCCCFCCCCCCCCCCFCVVCCCVVVVVVVC
60 60 A Q - 0 0 120 189 81 QQQQQQQQQQQQQLLLLLLLLLLTLLLLLLLLLLYLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
61 61 A D S S+ 0 0 141 189 40 EDDDDDDDDDDDDEDEEEEEEEEEDDEQEDEEEEDEEEDEEEEEEDEEEEEEEEEEEDDEEEDDDDDDDE
62 62 A F S S- 0 0 72 189 70 FFFFFFFFFFFFFYYYYYYYYYYYYYYYYYYYYYKYYYYYYYYYYYYYYYYYYYYHYQQYYYQQQQQQQY
63 63 A G - 0 0 36 189 67 GSSGPPVSSSSNSESEEEEEEEETEEEaEEQDEEREEEEEEEEEEEEEEEEEEEEEEKKEEEKKKKKKKE
64 64 A K + 0 0 129 183 54 KKKKKKKKKKKKKNKNNNNNNNNKNNNkGNNNNNKNNNNNNNNNNNNNNNNNNNNNNKKNNNKKKKKKKN
65 65 A R S S- 0 0 217 187 30 RRRRKKRRRRRRRRRRRRRRRRRKRRRKRRRRRRRRRRRRRRRRRRRRRRRRRRRRRPPRRRPPPPPPPR
66 66 A M S S- 0 0 103 188 88 MTTMTTTTTAATTPPPPPPPPPPEPPPGPPPPPPRPPPPPPPPPPPPPPPPPPPPPPTTPPPTTTTTTTP
67 67 A F S S+ 0 0 50 188 48 FLLLLLLFLLLLFLTLLLLLLLLGLLLFLLLLLLYLLLLLLLLLLLLLLLLLLLLLLIILHLIIIIIIIL
68 68 A V E - F 0 82A 4 189 48 VVVVVVVVVVVVVVVLLLLLVVVVLLAALVVVLLILLLLLLLLLVLLLLLLVLLLVLVVLLLVVVVVVVL
69 69 A F E - F 0 81A 1 189 29 FFFFFFFFFFFFFIFIIIIIIFFFIIFFIIIIIIFIIIIIIIIIMIIIIIIIIIILIIIIIIIIIIIIII
70 70 A K E -EF 56 80A 30 188 18 KKKKKKKKKKKKKKKKKKKKKKKRKKKMKKKKKKCKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
71 71 A I E -EF 55 79A 0 161 37 LVVIIIILLVVILLVLLLLLLLLLLLLMLLLLLLLLLLLLLLLLLLLLLLLLLLL.L..LLL.......L
72 72 A T E - F 0 78A 30 177 83 TTTTTTTRSSSTRR.KKRKKMLLTKKQMRRHHKKTKKKKKKKKKQKKKKKKRKKKLK..KKK.......K
73 73 A T E >> - F 0 77A 1 178 41 TTTTSSTTTTTTTTVTTTTTTTTSTTTNTTTTTTTTTTTTTTTTTTTTTTTTTTTHT..TTT.......T
74 74 A T T 34 S+ 0 0 86 189 89 AAGDEEEAAAAEAKNKKKKKKKKAQQKQRKKKQRAQQQQQQRQQKRQRRQRQQQQSRSSRRQSSSSSSSR
75 75 A K T 34 S- 0 0 151 189 74 KKKRKKKKKKKRKTKTTTTTSNNVTTHDTTSSTTATTTTTTTTTHTTTTTTKTTTKTVVTTTVVVVVVVT
76 76 A Q T <4 S+ 0 0 176 189 82 LKKKKKKNKNNKNNKNNNNNMGGGSSGRSSGGSSGSSSSSSSSSGSSSSSSSSSSPSHHSSSHHHHHHHS
77 77 A Q E < - F 0 73A 68 189 81 QQQQQQQQQQQQQTQTTTTTQVVTTTVHTTTATTLTTTTTTTTTVTTTTTTATTTGTRRTTARRRRRRRT
78 78 A D E - F 0 72A 58 188 60 DDDDDDDDDDDDDEEDDDDDEDDEEEDEDDHDEEEEEEEEEEEEDEEEEEEEEEEVETTEEETTTTTTTE
79 79 A H E - F 0 71A 1 188 63 HHHHHHHHHHHHHYLYYYYYHHHYYYHLYYHHYYYYYYYYYYYYHYYYYYYYYYYDYQQYYYQQQQQQQY
80 80 A F E +BF 14 70A 27 189 43 YFFFFFFYFYYFYFVFFFFFFFFLFFFIFFFFFFRFFFFFFFFFYFFFFFFFFFFHFEEFFFEEEEEEEF
81 81 A F E -BF 13 69A 0 189 23 FFFFFFFFFFFFFLMLLLLLFLLILLLMLLLLLLFLLLLLLLLLLLLLLLLLLLLFLIILLLIIIIIIIL
82 82 A Q E -BF 12 68A 37 189 63 QQQQQQQQQQQQQDQEEEEEEEEQEEEQEEEEEEHEEEEEEEEEEEEEEEEEEEELENNEEENNNNNNNE
83 83 A A - 0 0 8 189 9 AAAAAAAAAAAAASACCCCCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAEAAAAAAAAAAAAAA
84 84 A A S S- 0 0 34 189 77 STTSSSSSTTTSSCSCCCCCSCCASSCSCCCCCCSCCCCCCCCCCCCCCCCCCCCACDDCCCDDDDDDDC
85 85 A F S > S- 0 0 91 189 93 HHHHYYHHHHHHHSSSSSSSSSSNSSSTSSSSSSNSSSSSSSSSSSSSSSSSSSSLSTTSSSTTTTTTTS
86 86 A L H >> S+ 0 0 108 188 93 HLLVVVVLLLLVLRLRRRRRRRRDRRRVRRRRRRRRRRRRRRRRRRRRRRRRRRRRRVVRRRVVVVVVVR
87 87 A E H 3> S+ 0 0 121 189 30 EEEEEEEEEEEEEEEEEEEEEEEKEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE
88 88 A E H 3> S+ 0 0 18 189 18 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDDEDEDDDDDDDD
89 89 A R H < S+ 0 0 54 151 74 CCCCCCCCCCCCC C AKKDAAK AA AA AAAAAAAAANAAAAAANAA RATTAAATTTTTTTA
103 103 A I H >< S+ 0 0 43 150 84 ILLLLLLLLLLLL L ILLSGGL GG GG GGGGGGGGGLGGGGGGLGG LGLLGGGLLLLLLLG
104 104 A E T 3< S+ 0 0 97 148 51 EQQDEEAQQQQKQ Q QQQEQQQ QQ QQ QQQQQQQQQQQQQQQQCQQ RQGGQQQGGGGGGGQ
105 105 A G T < S+ 0 0 59 146 63 NGGGGGGGGGGDG PPPAPPA PP PP PPPPPPPPPTPPPPPPPPP APPPPPPPPPPPPPP
106 106 A L < + 0 0 96 80 28 GGGGGGGDGGGGD GSSKGGT GG GG GGGGGGGGGTGGGGGGGGG AG GGG G
107 107 A E - 0 0 140 80 49 QKKRKKKRVKKKR QEEHKKD KK KK KKKKKKKKKNKKKKKKKKK EK KKK K
108 108 A H + 0 0 162 35 54 RKKKRRKKKKKKK N R
109 109 A H - 0 0 183 32 8 FFFFFFFFFFFFF L
110 110 A H - 0 0 171 32 47 SAAAAAATAAAAT Q
111 111 A H + 0 0 160 31 4 RRRRRRRRRRRRR
112 112 A H 0 0 183 30 21 KKKKKKKKKKKKK
113 113 A H 0 0 240 2 73
## ALIGNMENTS 141 - 188
SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....5....:....6....:....7....:....8....:....9....:....0....:....1
1 1 A M 0 0 235 83 3 MV
2 2 A E + 0 0 168 113 13 N GE S D N
3 3 A P + 0 0 64 116 66 S Q GS Q P G G P
4 4 A K + 0 0 169 117 80 G K EK K A K QK K
5 5 A R - 0 0 62 117 93 I P PQ R R T LN K
6 6 A I S S- 0 0 71 130 36 L I I LVL IE T I I V FL I
7 7 A R E S+A 28 0A 91 148 39 K K Y RAT KH R KR KRE K MK R I R
8 8 A E E +A 27 0A 51 158 21 E E E ETEETSE EE QQ ET QEESES ETEA E T EE
9 9 A G E -A 26 0A 5 167 7 G G G G GGGGGYG GGGG GGTGGG GGGGGGGGQGGGGGGGGG
10 10 A Y E +A 25 0A 136 169 22 F Y W Y YFWYYFPFSYYY WYTFLYYCSWWWPWFDFWYEYWYYY
11 11 A L E -A 24 0A 2 170 9 M L L L LLLLLQLLVLLL LLMLLLLAVLCLLLLLLLLLLLLLL
12 12 A V E -AB 23 82A 16 171 45 V T H V VYEFHNTLIYLL HEMRQYLVIEVEYNTMTTLILMLYY
13 13 A K E -AB 22 81A 12 172 17 K K K K KRKKKEKRKKRR KKAKKKRHKKKKKKKSKKRKRKRKK
14 14 A K E + B 0 80A 14 179 46 RQKQ Q KQKLEQLKWKQTKK QQKAKQQKPQEQEKKRRLRKRKQKQQ
15 15 A G S S+ 0 0 20 183 30 GGAGGdGGGGGSSsLTFGsFFGGdsGGGGFqGSGSaDGGGGFGFGFSS
16 16 A S S S+ 0 0 82 176 85 HH.HHsHHHAGRRrSN.Gt..HHssHHHGKhGRARsSHHAD.H.E.KK
17 17 A V S S- 0 0 82 180 55 VIGIIGIIIDIVHVVV.RS..IIGFIVVLNIRVVVKSVITV.I.Y.II
18 18 A F S S- 0 0 193 187 70 VVVVVMVRVFAFVGAMKIKKKVVMFVRVDSVIFRFLGRVFIKFKIKVV
19 19 A N S S+ 0 0 129 187 59 QHQHHRHHHHpKwKHKnKdnnHHRgHRKrNHKKKKNlHHKRnPnKnKK
20 20 A T - 0 0 54 184 69 NN.NNLNNNTkSlQ.GgNdggNNLeNNNrGNNSSS.lNNTTgSgNgTT
21 21 A W + 0 0 55 186 2 WWWWWWWWWWWWWWPWWWWWWWWWWWWWWWWWWWW.WWWWWWWWWWWW
22 22 A K E -A 13 0A 136 187 26 KKKKKKKRKKHRKRNQQKKQQKKKQKLKQQKKRKRTKKKRRQRQRQTT
23 23 A P E +A 12 0A 88 187 76 VARAARATAKLKAKAHKKKKKAVRKADTKKAKKRRKRTVTRKTKRKPP
24 24 A M E -A 11 0A 15 189 67 RRYRRRRRRRRRRRARLRYLLRRRRRRRRLRRRRRFRRRRRLRLRLRR
25 25 A W E +AC 10 36A 29 189 2 WWWWWWWWWWWWYWWWWWLWWWWWWWWWWWWWWYWWWWWWWWWWWWYY
26 26 A V E -AC 9 35A 0 189 57 FFFFFFFFFFFFFFAFVCFVVFFFCFFFFVFCFFFVFFFFFVFVFVVV
27 27 A V E -AC 8 34A 0 189 20 AIVIIVIIIVVVVVSVVVIVVIIVVIVVVVIVVIVVVKVVVVRVVVTT
28 28 A L E -AC 7 33A 0 189 5 LLLLLLLLLMLLLLQLFLFFFLLLLLLLLFLLLLLLLLLLLLILLLLL
29 29 A L E > - C 0 32A 14 189 94 KRDRRARNRKKTQKTDTNKTTRRAGRTQVTRNTDTKSSKQKTETKTKK
30 30 A E T 3 S+ 0 0 128 189 54 SQDQQDQKQEQTKKGENEDNNQQDRQTNDNQETDTNNDQKDSNSESDD
31 31 A D T 3 S- 0 0 111 189 55 DNDNNYNTNQdTNdKnFEDFFNNYDNEDDFNETQTDYNNNGFGFGFGG
32 32 A G E < -CD 29 49A 8 189 84 RTVTTCTSTYcTGtGlCGVCCTMCLTGMFCTGTGTVCSTEKCFCNCLL
33 33 A I E -CD 28 48A 0 189 29 LLILLLLLLILLLLLLLLILLLLLFLLLLLLLLILLLLLLLLLLILII
34 34 A E E -CD 27 47A 42 189 98 LLTLLFLILWYYIYLSFHTFFLLFIVYFFFLHYSYSFRLRFYLYFYSS
35 35 A F E +CD 26 46A 3 189 9 YYYYYYYYYYYSYYFYFYYFFYYYYYYYYFYYTYSWYYYYWFYFWFYY
36 36 A Y E -C 25 0A 25 189 2 YYYYYYYYYFYFFYFYYFYYYYYYYYYFYYYFFYFYYYYYFYFYFYYY
37 37 A K S S+ 0 0 122 189 23 KKSKKKKKKPKKKKATKKKKKKKKAKKKSKKKKKKEKKKKLKKKKKKK
38 38 A K S > S- 0 0 156 189 92 YLSLLALNFKAAKTKSSSVSSLLVSLNDSTLSASVNDNLNDSSSESSS
39 39 A K T 3 S- 0 0 97 189 67 EEADEKERENKEKRRRHQSNNEEKEERKSHQQEDETSQEKPYKYSYKK
40 40 A S T 3 + 0 0 63 189 70 GGRGGDGEGTEKSESEQHKQQGGDKGSKSQGHKQKTRKGTSSNSSSKK
41 41 A D < - 0 0 63 189 47 ggGggsgDgGSQdDekDSkDDggsSgDsSDgSQEQDEHgDhDEDvDhh
42 42 A N S S+ 0 0 146 186 76 dtNttet.tSRYgKarDTkEEtteKtAkADtIYKYPETt.eEPDgDrr
43 43 A S S S- 0 0 70 188 63 sPlPPVPsPaDsRESgFEESSPPAQPKQTYPEsIsySVS.sAEAsAtt
44 44 A P - 0 0 48 185 23 hPpPPVPpPpPpPPPrP..PPPPVPPPPPPP.pPppVPP.tAPApAnn
45 45 A K S S- 0 0 99 189 41 RKEKKLKKKKLTLLARLKKLLKKLKKVKKLKKTITKLHKKRLILRLRR
46 46 A G E -D 35 0A 22 189 12 GGGGGGGGGGGEGGGGAGGAAGGGGGGGGAGGEREGGGGTGADAGAGG
47 47 A M E -D 34 0A 110 189 83 TRRRRSRHRIAIATICSSISSRRSTRVYISRSIMINSRQPVSRSVSSS
48 48 A I E -D 33 0A 3 189 13 IILIIIIIIIIIVIIVLIILLIIIFIVMVLIIIIIIIIIIILVLILWW
49 49 A P E -D 32 0A 34 189 84 LLALLPLTLEAQTVNRPLDPPLLPVLPARPLLPPQSPALRDPPPKPSS
50 50 A L S S+ 0 0 7 189 4 LLLLLLLLLLLLFLLLLLLLLLLLMLLLLLLLLLLLLLLALLLLALVV
51 51 A K S S+ 0 0 108 189 71 RDDDDPDIDDVAKASKLNFLLDDPKDFKDLDASKSQPEDLRLRLALSS
52 52 A G S S+ 0 0 33 189 29 NGGGGSGGGGNTDNDGGEHGGGGSgGSNRGGETeTYSNGNyGGGNGAA
53 53 A S - 0 0 17 180 69 CC.CC.CACN.VI..AYI.YYCC.sCA.LYCIIsV.YSCLlYSYCYVV
54 54 A T - 0 0 68 184 63 KT.TTYTATSYSSY.ITL.TTTTYVTS.RSTISSS.KTTDSTRTVTQQ
55 55 A L E -E 71 0A 47 186 57 II.IIVILISTTLTILVG.IIIIVRIVAAVISTCT.ILIESVVVTVKK
56 56 A T E -E 70 0A 31 187 61 TTKTTTTDTAVIYISGSV.NNTIVMTNSKSTVIKI.LATCTGSGVGTT
57 57 A S S S+ 0 0 76 188 66 CCSCCSCCCTSKITDITQSSSCCSACELPVCEKVK.FKCSSPKPKPII
58 58 A P S S- 0 0 89 187 39 PPTPPPPPPLRSDPVDPSVPPPPPPP.QAPPGSAS.CKPEAPKPGPPP
59 59 A C - 0 0 14 188 51 YCVCCVCTCVCCEATNSDKTTCCVHC.ARKCDCECCTCCCCGPGAGSS
60 60 A Q - 0 0 120 189 81 LLILLGLFLLGQIHKEEDQEELLTLLDTPELDQHQHPFLQDIFIEITT
61 61 A D S S+ 0 0 141 189 40 EEHEEPESEDDEGEDEKKEAAEEPRETDHAEKEGESRVERKQHQDQGG
62 62 A F S S- 0 0 72 189 70 YYLYYEYKYQAEDIGDDPFDDYYERYLKDDYPEPECEYYDTDDDVDFF
63 63 A G - 0 0 36 189 67 EETEEdEVEKATKGHGgtdggEEddEQSdgEaTsTecKeGGaRaVagg
64 64 A K + 0 0 129 183 54 NNTNNsNKNK.NK...nkkrrNNsrNRKehNkNqNanNrS.q.qNqaa
65 65 A R S S- 0 0 217 187 30 RRPRRRRKRPKKRRN.KRQKKRRRKRHRRKRRKRKSRTPHKK.KRKSS
66 66 A M S S- 0 0 103 188 88 PPAPPKPRPTQEKTE.DKKDDPPKDPQTEEPKEDEGKPPKEEPEQETT
67 67 A F S S+ 0 0 50 188 48 LLNLLYLWLIFNYHF.FYYFFLLYCLNHHHLYNNNTFHQGAYNYFYLL
68 68 A V E - F 0 82A 4 189 48 VLALLSLLLVSTCAVNVCSVVLLSCLVVAVLCTLTRTVLKSVTVAVGG
69 69 A F E - F 0 81A 1 189 29 IIFIIFILIIFFLFFFFFFFFIIFFILFFFIFFFFFFFLFFFFFFFFF
70 70 A K E -EF 56 80A 30 188 18 KKQKKKKKKKKKKKKTKKTKKKKKEKTeSKKKKEKKKKinEKeK.KSS
71 71 A I E -EF 55 79A 0 161 37 LLVLLALLL.II.A.......LLALLVs..L.I.I.VVlr..i.E.II
72 72 A T E - F 0 78A 30 177 83 EKVKKEKTK.TDIS.ILVLLLKKETKCALLKVDIDVVTRVILALILVV
73 73 A T E >> - F 0 77A 1 178 41 TTATTQTTT.KTHR.TQTIKKTTHSTTIPQTTTITRHTTVTSTSSSTT
74 74 A T T 34 S+ 0 0 86 189 89 NRSQRSRAQSFPAFLTFTTFFRQSGRVSAFQTPSPTQARFCFTFTFTT
75 75 A K T 34 S- 0 0 151 189 74 TTNTTGTETVGDDNNDKISKKTTGDTEKQKTIEADSGTTKMKKKRKNN
76 76 A Q T <4 S+ 0 0 176 189 82 SSASSMSGSHSQGTGSSDQTTSSMRSGNKSSDTGQEMGSWGNMNENQQ
77 77 A Q E < - F 0 73A 68 189 81 ETTTTRTKTRSTKRHKHRRHHTARRTKKKHTRTRTRRVTREHKHDHLL
78 78 A D E - F 0 72A 58 188 60 EEVEETEEETTFNTKTVKLVVEETSEDILVEKFT.NSEDTSTITTTLL
79 79 A H E - F 0 71A 1 188 63 HYLYYYYYYQH.YYHFYYYYYYYYYYYLYYYYFFFYYYYFHYFYMYVV
80 80 A F E +BF 14 70A 27 189 43 FFKFFYFMFEFYFYTHFRFFFFFYEFHYVFFRLFFTFPFYLFLFFFHH
81 81 A F E -BF 13 69A 0 189 23 LLVLLFLILIFLLFFFFILFFLLFFLIVLFLIMVLFFMLMFFLFFFFF
82 82 A Q E -BF 12 68A 37 189 63 EEFEESEEENAQCSQQRCARREESTEQQARECSQQTSQEYIRQRIRVV
83 83 A A - 0 0 8 189 9 AAAAAAAAASAACAAAAAAAAAAAAAAAAAAANAAAAAAACAAAAAAA
84 84 A A S S- 0 0 34 189 77 CCDCCDCPCDESFGARETEEECCDASSKSECTNYSDDPCTEEKEDEII
85 85 A F S > S- 0 0 91 189 93 MSTSSTSDSTTNSTTNSDTSSSSTSSTSYSSDNTNTTTSTTSDSSSSS
86 86 A L H >> S+ 0 0 108 188 93 RRKRRLRQRVENEEALDSEQQRRLPRRDLKRS.PNEQKREVEVEEEPP
87 87 A E H 3> S+ 0 0 121 189 30 EEEEEEEIEEEQDEEAYLEYYEEEAEDSEYELQGQSEVEQAHDHKHAA
88 88 A E H 3> S+ 0 0 18 189 18 EEEEEDESEDDEEEEETDETTEEDEEEEETEDEEDSDEDEETETETEE
89 89 A R H < S+ 0 0 54 151 74 A AAVARATC TTSAV A S A RA I I
103 103 A I H >< S+ 0 0 43 150 84 G GGLGLGL SSGGL G Y G LG Q Q
104 104 A E T 3< S+ 0 0 97 148 51 Q QQ QDQG QQQQ Q D Q SQ E E
105 105 A G T < S+ 0 0 59 146 63 P PP PPPS RRPP P S P SP S S
106 106 A L < + 0 0 96 80 28 G GG GSGN TTGG G G GG
107 107 A E - 0 0 140 80 49 K KK KKKT RRKK K K GK
108 108 A H + 0 0 162 35 54 Q LL K
109 109 A H - 0 0 183 32 8 FF
110 110 A H - 0 0 171 32 47 SS
111 111 A H + 0 0 160 31 4 RR
112 112 A H 0 0 183 30 21 M
113 113 A H 0 0 240 2 73 D
## SEQUENCE PROFILE AND ENTROPY
SeqNo PDBNo V L I M F W Y G A P S T C H R K Q E N D NOCC NDEL NINS ENTROPY RELENT WEIGHT
1 1 A 1 4 0 95 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 83 0 0 0.220 7 0.96
2 2 A 0 0 0 0 0 0 0 2 0 0 2 0 0 0 0 0 1 93 2 1 113 0 0 0.366 12 0.86
3 3 A 2 0 0 0 0 0 0 4 2 65 2 1 0 0 1 0 3 1 3 17 116 0 0 1.264 42 0.33
4 4 A 0 0 1 6 0 0 0 24 2 1 1 2 0 0 4 44 11 3 3 0 117 0 0 1.701 56 0.19
5 5 A 24 3 5 0 0 0 0 0 0 2 0 3 0 0 41 7 5 9 1 0 117 0 0 1.747 58 0.07
6 6 A 3 32 61 1 1 0 0 0 0 0 0 2 1 0 0 0 0 1 0 0 130 0 0 0.988 32 0.64
7 7 A 0 0 1 1 0 0 1 0 1 0 0 1 0 1 56 38 1 1 0 0 148 0 0 0.987 32 0.60
8 8 A 1 0 1 0 0 0 0 1 1 0 2 3 1 0 0 1 2 89 0 1 158 0 0 0.591 19 0.79
9 9 A 0 0 0 0 1 0 1 96 0 0 0 1 0 0 0 0 1 0 0 0 167 0 0 0.203 6 0.92
10 10 A 0 2 0 0 30 5 58 0 0 1 1 1 1 0 0 0 0 1 0 1 169 1 0 1.153 38 0.78
11 11 A 1 95 0 1 0 0 0 0 1 1 0 0 1 0 1 0 1 0 0 0 170 0 0 0.307 10 0.90
12 12 A 74 5 2 2 1 0 4 0 1 0 0 3 0 2 1 1 1 2 1 0 171 0 0 1.183 39 0.54
13 13 A 1 1 0 1 1 0 0 0 1 1 1 0 0 1 5 88 1 1 0 0 172 0 0 0.585 19 0.82
14 14 A 0 2 0 0 0 1 0 0 1 1 1 1 0 0 33 49 11 2 0 0 179 1 0 1.263 42 0.54
15 15 A 0 1 0 0 4 0 0 85 1 0 5 1 0 0 1 1 1 0 1 2 183 8 7 0.697 23 0.69
16 16 A 1 0 0 0 0 0 0 2 8 0 35 12 0 35 3 2 0 1 2 1 176 0 0 1.604 53 0.15
17 17 A 38 7 26 16 1 0 1 2 0 0 1 1 0 1 1 1 0 0 1 6 180 0 0 1.699 56 0.44
18 18 A 33 10 2 2 43 0 0 1 1 0 1 0 0 1 3 4 0 0 0 1 187 0 0 1.524 50 0.30
19 19 A 0 1 0 0 0 1 0 1 0 2 1 0 0 35 4 8 2 0 47 1 187 3 14 1.320 44 0.40
20 20 A 0 2 0 0 0 0 0 4 0 0 16 37 0 0 1 2 1 1 36 1 184 0 0 1.448 48 0.30
21 21 A 0 0 0 0 0 99 0 0 0 1 0 0 0 0 0 0 0 0 0 0 186 0 0 0.033 1 0.98
22 22 A 0 1 0 0 0 0 0 0 0 0 2 2 0 1 6 83 5 0 1 0 187 0 0 0.707 23 0.74
23 23 A 14 1 0 1 0 0 0 0 27 34 0 4 0 1 4 14 0 0 0 1 187 0 0 1.652 55 0.23
24 24 A 10 4 0 34 1 0 1 0 1 0 0 1 0 0 50 0 0 0 0 0 189 0 0 1.192 39 0.32
25 25 A 0 1 0 0 0 97 2 0 0 0 0 0 0 0 0 0 0 0 0 0 189 0 0 0.135 4 0.98
26 26 A 49 0 1 1 48 0 0 0 1 0 0 0 2 0 0 0 0 0 0 0 189 0 0 0.851 28 0.43
27 27 A 75 0 19 1 0 0 0 0 1 0 1 3 0 0 1 1 0 0 0 0 189 0 0 0.786 26 0.80
28 28 A 0 91 1 5 3 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 189 0 0 0.393 13 0.95
29 29 A 1 37 0 1 1 0 1 1 3 0 10 9 0 1 20 13 2 1 2 2 189 0 0 1.914 63 0.05
30 30 A 0 0 0 0 0 0 0 1 0 2 5 2 0 0 1 2 24 42 5 16 189 0 0 1.611 53 0.45
31 31 A 0 0 0 0 4 0 2 3 0 0 1 2 0 0 0 1 6 3 23 58 189 0 3 1.337 44 0.44
32 32 A 2 2 0 2 1 0 5 42 5 0 2 22 6 0 2 7 0 2 1 0 189 0 0 1.883 62 0.16
33 33 A 4 49 46 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189 0 0 0.918 30 0.71
34 34 A 7 23 2 1 6 5 5 0 1 0 3 2 1 1 1 1 0 43 0 1 189 0 0 1.832 61 0.02
35 35 A 0 0 0 0 48 2 49 0 0 0 1 1 0 0 0 0 0 0 0 0 189 0 0 0.844 28 0.90
36 36 A 0 0 0 0 18 0 82 0 0 0 0 0 0 0 0 0 0 0 0 0 189 0 0 0.471 15 0.98
37 37 A 0 1 0 0 0 0 0 0 1 5 1 1 0 0 0 89 1 1 0 1 189 0 0 0.511 17 0.77
38 38 A 2 20 2 0 2 0 5 0 2 1 8 2 1 0 6 45 1 1 3 2 189 0 0 1.861 62 0.08
39 39 A 1 0 0 0 0 0 2 0 1 1 2 1 0 1 3 50 3 26 6 2 189 0 0 1.548 51 0.33
40 40 A 0 0 3 0 0 0 0 29 3 0 33 17 1 1 1 5 3 3 2 1 189 0 0 1.796 59 0.30
41 41 A 1 0 0 0 0 0 0 33 0 0 6 0 0 2 0 1 2 3 0 52 189 3 66 1.203 40 0.52
42 42 A 1 0 1 0 0 0 2 1 2 1 10 19 0 1 8 3 1 8 36 8 186 0 0 1.976 65 0.24
43 43 A 2 1 1 0 1 0 1 1 9 20 55 2 0 0 1 1 1 3 3 1 188 3 40 1.537 51 0.36
44 44 A 2 1 0 0 0 0 0 0 3 87 1 1 0 1 1 0 4 0 1 0 185 0 0 0.641 21 0.76
45 45 A 1 7 1 0 0 0 0 0 2 0 0 2 0 1 7 79 0 1 0 0 189 0 0 0.844 28 0.59
46 46 A 0 0 0 0 0 0 0 93 4 0 0 1 0 0 1 0 0 2 1 1 189 0 0 0.370 12 0.88
47 47 A 8 0 4 44 0 1 1 0 2 1 8 2 1 1 22 4 4 0 1 0 189 0 0 1.774 59 0.17
48 48 A 6 4 88 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189 0 0 0.517 17 0.87
49 49 A 3 28 0 0 1 0 0 0 2 53 2 1 0 0 2 1 1 6 1 2 189 0 0 1.432 47 0.15
50 50 A 1 97 0 1 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 189 0 0 0.183 6 0.95
51 51 A 1 5 1 0 1 0 0 0 2 2 3 0 0 0 2 51 1 1 1 31 189 0 0 1.373 45 0.28
52 52 A 0 0 0 0 0 0 1 81 1 0 2 2 0 1 1 0 0 3 4 5 189 9 3 0.857 28 0.70
53 53 A 2 2 2 0 0 0 4 0 12 0 37 1 34 0 0 0 0 0 6 0 180 0 0 1.578 52 0.31
54 54 A 9 2 2 0 1 0 2 0 2 0 15 60 0 0 2 3 3 0 0 1 184 0 0 1.443 48 0.37
55 55 A 8 38 39 1 1 0 0 1 1 0 6 3 1 0 1 1 0 1 0 0 186 0 0 1.513 50 0.42
56 56 A 5 4 5 1 0 0 1 2 6 0 5 60 1 1 0 2 1 0 6 1 187 0 0 1.598 53 0.39
57 57 A 6 1 2 0 1 0 0 0 1 2 47 2 30 0 0 3 1 1 4 1 188 1 0 1.547 51 0.33
58 58 A 1 5 0 0 0 0 0 1 2 81 3 1 1 2 1 1 1 1 0 1 187 0 0 0.904 30 0.60
59 59 A 7 0 0 0 4 0 1 2 2 1 2 3 76 1 1 1 0 1 1 1 188 0 0 1.119 37 0.49
60 60 A 0 36 3 0 2 0 1 1 0 1 0 3 0 2 0 1 47 3 0 2 189 0 0 1.389 46 0.19
61 61 A 1 0 0 0 0 0 0 2 2 1 1 1 0 2 2 2 2 33 0 53 189 0 0 1.296 43 0.60
62 62 A 1 1 1 0 46 0 31 1 1 2 0 1 1 1 1 2 5 3 0 6 189 0 0 1.563 52 0.30
63 63 A 2 0 0 0 0 0 0 39 5 1 6 3 1 1 1 6 1 29 2 3 189 6 21 1.807 60 0.32
64 64 A 0 0 0 0 0 0 0 1 2 0 2 1 0 1 3 57 2 1 33 0 183 0 0 1.117 37 0.46
65 65 A 0 0 0 0 0 0 0 0 0 6 2 1 0 1 79 10 1 0 1 0 187 0 0 0.792 26 0.69
66 66 A 0 2 0 35 0 0 0 1 2 31 0 14 0 0 1 4 2 6 0 3 188 0 0 1.711 57 0.11
67 67 A 0 38 5 0 40 1 5 1 1 0 0 1 1 3 0 0 1 0 4 0 188 0 0 1.487 49 0.52
68 68 A 62 24 1 0 0 0 0 1 3 0 3 3 2 0 1 1 0 0 1 0 189 0 0 1.178 39 0.51
69 69 A 0 6 31 1 62 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189 1 0 0.851 28 0.70
70 70 A 0 0 1 1 0 0 0 0 0 0 2 2 1 0 1 91 1 3 1 0 188 28 4 0.482 16 0.81
71 71 A 6 52 37 1 1 0 0 0 2 0 1 0 0 0 1 0 0 1 0 0 161 1 0 1.101 36 0.62
72 72 A 5 7 3 1 0 0 0 0 3 0 5 44 1 1 5 23 1 2 0 2 177 0 0 1.833 61 0.16
73 73 A 2 0 2 1 0 0 0 0 4 1 6 78 0 2 1 2 2 0 1 0 178 0 0 1.022 34 0.59
74 74 A 1 1 1 0 5 0 0 1 14 3 8 30 1 0 9 8 13 2 2 3 189 0 0 2.195 73 0.11
75 75 A 6 0 1 1 0 0 0 2 1 0 3 25 0 1 2 50 1 2 4 3 189 0 0 1.598 53 0.26
76 76 A 0 2 0 3 0 1 0 8 1 1 24 2 0 6 1 9 34 1 8 1 189 0 0 1.964 65 0.18
77 77 A 3 2 0 0 0 0 0 1 2 0 1 26 0 7 11 4 43 1 0 1 189 1 0 1.637 54 0.19
78 78 A 3 2 1 0 1 0 0 0 1 0 2 11 0 1 0 2 0 24 2 51 188 1 0 1.492 49 0.39
79 79 A 1 2 0 1 3 0 37 0 0 0 0 0 0 49 0 0 6 0 0 1 188 0 0 1.188 39 0.36
80 80 A 1 2 1 1 74 0 10 0 0 1 0 1 0 3 2 1 0 6 0 0 189 0 0 1.086 36 0.56
81 81 A 2 32 8 3 56 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189 0 0 1.052 35 0.76
82 82 A 1 1 1 0 1 0 1 0 2 0 3 1 2 1 4 0 51 29 5 1 189 0 0 1.490 49 0.37
83 83 A 0 0 0 0 0 0 0 0 94 0 1 0 4 0 0 0 0 1 1 0 189 0 0 0.282 9 0.90
84 84 A 0 0 1 0 1 0 1 1 31 1 18 5 26 0 1 1 0 5 1 8 189 0 0 1.826 60 0.22
85 85 A 0 1 0 1 22 0 11 0 0 0 35 13 0 12 0 0 0 0 3 2 189 1 0 1.714 57 0.07
86 86 A 12 40 0 0 0 0 0 0 1 2 1 0 0 1 30 2 3 5 1 2 188 0 0 1.624 54 0.06
87 87 A 1 1 1 0 0 0 2 1 3 0 1 0 0 2 0 1 2 84 0 3 189 0 0 0.794 26 0.69
88 88 A 0 0 0 0 0 0 0 0 0 0 1 4 0 0 0 0 0 84 0 11 189 0 0 0.560 18 0.82
89 89 A 0 1 0 5 2 0 3 0 6 0 0 0 1 0 80 3 0 0 0 0 189 0 0 0.823 27 0.54
90 90 A 0 1 0 1 0 0 0 1 1 0 1 0 0 0 1 6 1 15 4 69 189 0 0 1.112 37 0.64
91 91 A 3 4 1 2 3 0 0 4 54 0 15 1 1 1 4 0 0 4 1 3 189 0 0 1.723 57 0.33
92 92 A 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189 0 0 0.000 0 1.00
93 93 A 53 4 7 3 1 0 0 0 31 0 1 1 0 0 0 0 1 0 1 0 189 0 0 1.261 42 0.40
94 94 A 1 4 0 0 21 0 0 2 3 0 2 1 0 1 33 14 2 6 2 10 189 0 0 1.979 66 -0.02
95 95 A 5 2 0 1 0 0 1 0 14 0 4 0 0 0 0 0 1 22 0 52 189 0 0 1.386 46 0.40
96 96 A 3 6 86 2 1 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 189 0 0 0.601 20 0.86
97 97 A 0 1 1 1 0 0 0 3 1 0 3 26 0 0 5 42 1 4 10 2 189 0 0 1.726 57 0.23
98 98 A 0 1 0 0 1 0 0 24 4 0 6 1 0 0 14 40 3 1 6 1 187 0 0 1.719 57 0.21
99 99 A 4 2 1 0 0 0 0 0 83 0 1 2 1 5 1 0 0 1 1 0 185 0 0 0.779 25 0.64
100 100 A 10 4 74 3 0 0 0 0 3 0 2 5 0 0 0 0 0 0 0 0 180 0 0 0.997 33 0.69
101 101 A 1 0 0 0 0 0 0 0 1 0 1 13 0 28 3 39 9 1 3 1 171 0 0 1.630 54 0.26
102 102 A 1 0 1 0 0 0 0 0 25 0 1 8 56 1 2 2 0 0 1 1 151 0 0 1.350 45 0.26
103 103 A 0 24 47 0 0 0 1 25 0 0 2 0 0 0 0 0 1 0 0 0 150 0 0 1.215 40 0.15
104 104 A 0 1 0 0 0 0 0 7 1 0 1 0 1 0 1 1 40 41 0 7 148 0 0 1.347 44 0.48
105 105 A 0 0 0 0 0 0 0 53 3 36 3 1 0 0 1 0 0 1 1 1 146 0 0 1.137 37 0.37
106 106 A 0 1 0 0 0 0 0 84 1 0 4 5 0 0 0 1 0 0 1 3 80 0 0 0.733 24 0.72
107 107 A 1 0 0 0 0 0 0 1 0 0 0 1 0 1 6 66 15 5 1 1 80 0 0 1.209 40 0.50
108 108 A 0 6 0 0 0 0 0 0 0 0 0 0 0 3 34 51 3 0 3 0 35 0 0 1.177 39 0.46
109 109 A 0 3 0 0 94 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 32 0 0 0.277 9 0.91
110 110 A 0 0 0 0 0 0 0 0 72 0 16 6 0 3 0 0 3 0 0 0 32 0 0 0.917 30 0.53
111 111 A 0 0 0 0 0 0 0 0 0 0 0 0 0 3 97 0 0 0 0 0 31 0 0 0.143 4 0.96
112 112 A 0 0 0 3 0 0 0 0 0 0 0 0 0 3 3 90 0 0 0 0 30 0 0 0.435 14 0.78
113 113 A 0 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 50 2 0 0 0.693 23 0.27
## INSERTION LIST
AliNo IPOS JPOS Len Sequence
81 20 20 2 nSNs
84 36 44 2 gKKe
84 38 48 1 sSp
86 36 47 2 gKKe
86 38 51 1 sSp
87 36 44 2 gKKe
87 38 48 1 sSp
88 37 37 2 gKKe
88 39 41 1 sSp
89 41 44 2 gKKe
89 43 48 1 pSp
90 41 44 2 gKKe
90 43 48 1 pSp
91 36 44 2 gKRd
91 38 48 1 sCt
92 37 46 2 gKRd
92 39 50 1 sCq
93 37 44 2 gKRd
93 39 48 1 sCq
95 42 42 3 gRRVn
96 42 42 3 gRRVn
97 41 46 2 gKRd
97 43 50 1 sCq
98 17 20 2 kRTn
98 40 45 1 sLp
98 60 66 1 aNk
99 41 44 2 gRKe
99 43 48 1 tSp
100 32 32 2 gRKe
100 34 36 1 vLp
101 37 45 2 sQKd
101 39 49 1 sCq
102 41 46 2 sKKd
102 43 50 1 sCq
103 42 42 3 gRKVt
104 42 42 3 gRRVt
106 42 42 3 gRKVn
107 42 42 3 gRRVt
108 42 42 3 gRRVt
109 42 42 3 gRRVt
110 42 42 3 gRRVt
111 42 42 3 gRRVt
112 42 42 3 gRKVt
113 42 42 3 gRRVt
114 42 42 3 gRRVt
115 41 46 2 gKKd
115 43 50 1 sCq
116 42 42 3 gRRVa
117 42 42 3 gRRVt
118 42 287 3 gQKVt
119 42 42 3 gRKVt
120 42 42 3 gRRVt
121 42 42 3 gRKVt
122 41 47 2 sRKd
122 43 51 1 sSl
123 42 42 3 gRKVt
124 37 38 3 gRRVt
125 26 26 3 gRRVt
126 37 44 2 gKKd
126 39 48 1 sSq
127 42 42 3 gRRVt
128 38 60 1 aQp
129 38 87 1 aQp
130 42 42 3 gRKVt
131 30 46 3 gRKVn
132 41 42 3 gRRVt
133 38 60 1 aQp
134 38 87 1 aQp
135 38 87 1 aQp
136 38 87 1 aQp
137 38 87 1 aQp
138 38 60 1 aQp
139 38 60 1 aQp
140 29 49 3 gRKVn
141 41 47 2 gKRd
141 43 51 1 sCh
142 29 29 3 gRKVt
143 35 46 1 lIp
144 29 29 3 gRKVt
145 28 44 3 gRKVt
146 8 70 1 dSs
146 34 97 2 sREe
146 55 120 2 dRIs
147 28 28 3 gRKVt
148 38 56 1 sHp
149 29 29 3 gRKVt
150 37 60 1 aQp
151 18 1643 1 pKk
151 30 1656 1 dNc
152 37 51 1 sNp
153 15 25 1 wKl
153 37 48 2 dCAg
154 16 1982 2 sGGr
154 32 2000 1 dNt
155 41 124 2 eDKa
156 25 31 2 nSGl
156 35 43 2 kMMr
156 37 47 1 gVr
157 9 445 2 nSNg
157 53 491 1 gIn
158 58 58 1 tTk
159 14 1219 2 sRPt
159 18 1225 2 dAGd
159 40 1249 3 kNKKk
159 57 1269 2 dRPk
160 10 914 2 nSNg
160 54 960 1 gIr
161 10 903 2 nSNg
161 54 949 1 gIr
162 28 28 3 gRRVt
163 29 29 3 gRRVt
164 8 70 1 dSs
164 34 97 2 sREe
164 55 120 2 dRIs
165 9 27 3 sKDHs
165 13 34 1 gSe
165 46 68 1 gYs
165 57 80 1 dSr
166 41 42 3 gRKVt
168 36 65 2 sTSk
168 63 94 2 eINs
169 14 80 1 rRr
169 58 125 1 dPe
170 55 128 1 gVh
171 9 17 1 qGh
171 35 44 3 gRKVt
172 62 72 1 aTk
173 38 51 1 sNp
174 48 330 1 eIs
174 59 342 1 sIq
175 37 51 1 sNp
176 11 450 2 aSRs
176 37 478 1 yFp
176 51 493 1 eAa
177 12 62 1 lKl
177 56 107 1 cKn
179 39 44 3 gRKGt
179 61 69 1 eTr
179 68 77 1 iKl
180 61 97 2 nVFr
181 36 253 3 hVTPe
181 38 258 1 sKt
181 47 268 1 yCl
182 10 484 2 nSSg
182 54 530 1 aVq
183 67 203 1 eLi
184 10 1065 2 nSSg
184 54 1111 1 aVq
185 36 63 2 vTRg
185 38 67 1 sRp
186 10 471 2 nSSg
186 54 517 1 aVq
187 35 97 3 hAVEr
187 37 102 1 tQn
187 57 123 5 gGSKLHa
188 35 97 3 hAVEr
188 37 102 1 tQn
188 57 123 5 gGSKLHa
//