Complet list of 1jrj hssp file
Complete list of 1jrj.hssp file
HSSP HOMOLOGY DERIVED SECONDARY STRUCTURE OF PROTEINS , VERSION 2.0 2011
PDBID 1JRJ
THRESHOLD according to: t(L)=(290.15 * L ** -0.562) + 5
REFERENCE Sander C., Schneider R. : Database of homology-derived protein structures. Proteins, 9:56-68 (1991).
CONTACT Maintained at http://www.cmbi.ru.nl/ by Maarten L. Hekkelman
DATE file generated on 2014-05-02
HEADER HORMONE/GROWTH FACTOR 13-AUG-01 1JRJ
COMPND MOL_ID: 1; MOLECULE: EXENDIN-4; CHAIN: A; ENGINEERED: YES
SOURCE MOL_ID: 1; SYNTHETIC: YES; OTHER_DETAILS: THE PROTEIN WAS PRODUCED USI
AUTHOR J.W.NEIDIGH,R.M.FESINMEYER,K.S.PRICKETT,N.H.ANDERSEN
DBREF 1JRJ A 1 39 UNP P26349 EXE4_HELSU 1 39
SEQLENGTH 39
NCHAIN 1 chain(s) in 1JRJ data set
NALIGN 68
NOTATION : ID: EMBL/SWISSPROT identifier of the aligned (homologous) protein
NOTATION : STRID: if the 3-D structure of the aligned protein is known, then STRID is the Protein Data Bank identifier as taken
NOTATION : from the database reference or DR-line of the EMBL/SWISSPROT entry
NOTATION : %IDE: percentage of residue identity of the alignment
NOTATION : %SIM (%WSIM): (weighted) similarity of the alignment
NOTATION : IFIR/ILAS: first and last residue of the alignment in the test sequence
NOTATION : JFIR/JLAS: first and last residue of the alignment in the alignend protein
NOTATION : LALI: length of the alignment excluding insertions and deletions
NOTATION : NGAP: number of insertions and deletions in the alignment
NOTATION : LGAP: total length of all insertions and deletions
NOTATION : LSEQ2: length of the entire sequence of the aligned protein
NOTATION : ACCNUM: SwissProt accession number
NOTATION : PROTEIN: one-line description of aligned protein
NOTATION : SeqNo,PDBNo,AA,STRUCTURE,BP1,BP2,ACC: sequential and PDB residue numbers, amino acid (lower case = Cys), secondary
NOTATION : structure, bridge partners, solvent exposure as in DSSP (Kabsch and Sander, Biopolymers 22, 2577-2637(1983)
NOTATION : VAR: sequence variability on a scale of 0-100 as derived from the NALIGN alignments
NOTATION : pair of lower case characters (AvaK) in the alignend sequence bracket a point of insertion in this sequence
NOTATION : dots (....) in the alignend sequence indicate points of deletion in this sequence
NOTATION : SEQUENCE PROFILE: relative frequency of an amino acid type at each position. Asx and Glx are in their
NOTATION : acid/amide form in proportion to their database frequencies
NOTATION : NOCC: number of aligned sequences spanning this position (including the test sequence)
NOTATION : NDEL: number of sequences with a deletion in the test protein at this position
NOTATION : NINS: number of sequences with an insertion in the test protein at this position
NOTATION : ENTROPY: entropy measure of sequence variability at this position
NOTATION : RELENT: relative entropy, i.e. entropy normalized to the range 0-100
NOTATION : WEIGHT: conservation weight
## PROTEINS : identifier and alignment statistics
NR. ID STRID %IDE %WSIM IFIR ILAS JFIR JLAS LALI NGAP LGAP LSEQ2 ACCNUM PROTEIN
1 : EXE4_HELSC 1.00 1.00 1 39 48 86 39 0 0 87 C6EVG1 Exendin-4 OS=Heloderma suspectum cinctum PE=2 SV=1
2 : EXE4_HELSU 1.00 1.00 1 39 48 86 39 0 0 87 P26349 Exendin-4 OS=Heloderma suspectum PE=1 SV=2
3 : EXE3_HELHO 0.95 1.00 1 39 48 86 39 0 0 87 P20394 Exendin-3 OS=Heloderma horridum horridum PE=1 SV=2
4 : W5L248_ASTMX 0.50 0.78 1 32 88 119 32 0 0 121 W5L248 Uncharacterized protein OS=Astyanax mexicanus PE=4 SV=1
5 : GLUC2_XENLA 0.48 0.73 1 33 180 212 33 0 0 219 O42144 Glucagon-2 OS=Xenopus laevis GN=gcg2 PE=2 SV=1
6 : GLUC_ICTPU 0.48 0.79 1 33 38 70 33 0 0 71 P04093 Glucagon (Fragment) OS=Ictalurus punctatus GN=gcg PE=1 SV=2
7 : Q6RYB2_BUFMA 0.48 0.73 1 33 63 95 33 0 0 149 Q6RYB2 Proglucagon (Fragment) OS=Bufo marinus PE=2 SV=1
8 : A2AS86_MOUSE 0.47 0.67 1 36 98 133 36 0 0 173 A2AS86 Glucagon (Fragment) OS=Mus musculus GN=Gcg PE=3 SV=1
9 : D2HQW4_AILME 0.47 0.67 1 36 98 133 36 0 0 179 D2HQW4 Putative uncharacterized protein (Fragment) OS=Ailuropoda melanoleuca GN=PANDA_014319 PE=3 SV=1
10 : E2RPI2_CANFA 0.47 0.67 1 36 98 133 36 0 0 178 E2RPI2 Glucagon OS=Canis familiaris GN=GCG PE=3 SV=2
11 : F1RPQ1_PIG 0.47 0.67 1 36 98 133 36 0 0 180 F1RPQ1 Glucagon OS=Sus scrofa GN=GCG PE=3 SV=1
12 : F7ABP1_HORSE 0.47 0.67 1 36 98 133 36 0 0 180 F7ABP1 Uncharacterized protein OS=Equus caballus GN=GCG PE=3 SV=1
13 : F7EF82_MACMU 0.47 0.67 1 36 101 136 36 0 0 182 F7EF82 Uncharacterized protein OS=Macaca mulatta GN=GCG PE=3 SV=1
14 : F7EF88_MACMU 0.47 0.67 1 36 98 133 36 0 0 180 F7EF88 Uncharacterized protein OS=Macaca mulatta GN=GCG PE=3 SV=1
15 : F7F3N7_MONDO 0.47 0.67 1 36 99 134 36 0 0 181 F7F3N7 Uncharacterized protein OS=Monodelphis domestica GN=GCG PE=3 SV=2
16 : F7ID40_CALJA 0.47 0.67 1 36 98 133 36 0 0 179 F7ID40 Uncharacterized protein OS=Callithrix jacchus GN=GCG PE=3 SV=1
17 : G1LG74_AILME 0.47 0.67 1 36 119 154 36 0 0 207 G1LG74 Uncharacterized protein (Fragment) OS=Ailuropoda melanoleuca GN=GCG PE=3 SV=1
18 : G1QG18_MYOLU 0.47 0.63 1 38 98 135 38 0 0 178 G1QG18 Uncharacterized protein OS=Myotis lucifugus PE=3 SV=1
19 : G1QQ90_NOMLE 0.47 0.67 1 36 181 216 36 0 0 263 G1QQ90 Uncharacterized protein OS=Nomascus leucogenys GN=GCG PE=3 SV=2
20 : G1TRR9_RABIT 0.47 0.67 1 36 98 133 36 0 0 180 G1TRR9 Uncharacterized protein OS=Oryctolagus cuniculus GN=LOC100341777 PE=3 SV=1
21 : G3HZV5_CRIGR 0.47 0.67 1 36 480 515 36 0 0 561 G3HZV5 Seprase OS=Cricetulus griseus GN=I79_016619 PE=3 SV=1
22 : G3MYS1_BOVIN 0.47 0.67 1 36 179 214 36 0 0 266 G3MYS1 Glucagon OS=Bos taurus GN=GCG PE=3 SV=1
23 : G3QHC4_GORGO 0.47 0.67 1 36 101 136 36 0 0 183 G3QHC4 Uncharacterized protein OS=Gorilla gorilla gorilla GN=101141703 PE=3 SV=1
24 : G3SE96_GORGO 0.47 0.67 1 36 98 133 36 0 0 180 G3SE96 Uncharacterized protein OS=Gorilla gorilla gorilla GN=101141703 PE=3 SV=1
25 : G3SWM5_LOXAF 0.47 0.67 1 36 98 133 36 0 0 178 G3SWM5 Uncharacterized protein OS=Loxodonta africana GN=GCG PE=3 SV=1
26 : G3V6P5_RAT 0.47 0.67 1 36 98 133 36 0 0 180 G3V6P5 Glucagon OS=Rattus norvegicus GN=Gcg PE=3 SV=1
27 : G3WZV6_SARHA 0.47 0.67 1 36 97 132 36 0 0 179 G3WZV6 Uncharacterized protein OS=Sarcophilus harrisii GN=GCG PE=3 SV=1
28 : G3WZV7_SARHA 0.47 0.67 1 36 97 132 36 0 0 180 G3WZV7 Uncharacterized protein OS=Sarcophilus harrisii GN=GCG PE=3 SV=1
29 : G5AKB5_HETGA 0.47 0.67 1 36 98 133 36 0 0 179 G5AKB5 Glucagon OS=Heterocephalus glaber GN=GW7_07689 PE=3 SV=1
30 : G7N866_MACMU 0.47 0.67 1 36 101 136 36 0 0 182 G7N866 Putative uncharacterized protein OS=Macaca mulatta GN=EGK_04477 PE=3 SV=1
31 : G7PKP1_MACFA 0.47 0.67 1 36 101 136 36 0 0 182 G7PKP1 Putative uncharacterized protein OS=Macaca fascicularis GN=EGM_04002 PE=3 SV=1
32 : GLUC_BOVIN 0.47 0.67 1 36 98 133 36 0 0 180 P01272 Glucagon OS=Bos taurus GN=GCG PE=1 SV=1
33 : GLUC_CANFA 0.47 0.67 1 36 98 133 36 0 0 180 P29794 Glucagon OS=Canis familiaris GN=GCG PE=1 SV=2
34 : GLUC_CARAU 0.47 0.75 1 32 88 119 32 0 0 121 P79695 Glucagon OS=Carassius auratus GN=gcg PE=2 SV=1
35 : GLUC_CAVPO 0.47 0.67 1 36 98 133 36 0 0 180 P05110 Glucagon OS=Cavia porcellus GN=GCG PE=1 SV=1
36 : GLUC_HUMAN 0.47 0.67 1 36 98 133 36 0 0 180 P01275 Glucagon OS=Homo sapiens GN=GCG PE=1 SV=3
37 : GLUC_MESAU 0.47 0.67 1 36 98 133 36 0 0 180 P01273 Glucagon OS=Mesocricetus auratus GN=GCG PE=2 SV=2
38 : GLUC_MOUSE 0.47 0.67 1 36 98 133 36 0 0 180 P55095 Glucagon OS=Mus musculus GN=Gcg PE=1 SV=1
39 : GLUC_OCTDE 0.47 0.67 1 36 98 133 36 0 0 180 P22890 Glucagon OS=Octodon degus GN=GCG PE=2 SV=1
40 : GLUC_PIAME 0.47 0.78 1 32 38 69 32 0 0 71 P81880 Glucagon (Fragment) OS=Piaractus mesopotamicus GN=gcg PE=1 SV=1
41 : GLUC_PIG 0.47 0.67 1 36 98 133 36 0 0 180 P01274 Glucagon OS=Sus scrofa GN=GCG PE=1 SV=4
42 : GLUC_RAT 0.47 0.67 1 36 98 133 36 0 0 180 P06883 Glucagon OS=Rattus norvegicus GN=Gcg PE=1 SV=1
43 : GLUC_SHEEP 0.47 0.67 1 36 98 133 36 0 0 176 Q8MJ25 Glucagon (Fragment) OS=Ovis aries GN=GCG PE=2 SV=1
44 : H0X7B1_OTOGA 0.47 0.64 1 36 98 133 36 0 0 180 H0X7B1 Uncharacterized protein OS=Otolemur garnettii GN=GCG PE=3 SV=1
45 : H2P7N4_PONAB 0.47 0.67 1 36 98 133 36 0 0 180 H2P7N4 Uncharacterized protein OS=Pongo abelii GN=GCG PE=3 SV=1
46 : H2QIW1_PANTR 0.47 0.67 1 36 98 133 36 0 0 180 H2QIW1 Uncharacterized protein OS=Pan troglodytes GN=GCG PE=3 SV=1
47 : I3M535_SPETR 0.47 0.67 1 36 98 133 36 0 0 180 I3M535 Uncharacterized protein OS=Spermophilus tridecemlineatus GN=GCG PE=3 SV=1
48 : L5K2B6_PTEAL 0.47 0.67 1 36 378 413 36 0 0 459 L5K2B6 Seprase OS=Pteropus alecto GN=PAL_GLEAN10025906 PE=3 SV=1
49 : L8IJL8_9CETA 0.47 0.67 1 36 98 133 36 0 0 179 L8IJL8 Glucagon OS=Bos mutus GN=M91_05757 PE=3 SV=1
50 : L9JDR4_TUPCH 0.47 0.67 1 36 98 133 36 0 0 179 L9JDR4 Glucagon OS=Tupaia chinensis GN=TREES_T100003465 PE=3 SV=1
51 : M3XDH4_FELCA 0.47 0.67 1 36 121 156 36 0 0 209 M3XDH4 Uncharacterized protein (Fragment) OS=Felis catus GN=GCG PE=3 SV=1
52 : M3XNA6_MUSPF 0.47 0.67 1 36 98 133 36 0 0 180 M3XNA6 Uncharacterized protein OS=Mustela putorius furo GN=GCG PE=3 SV=1
53 : Q6RYB6_PRODO 0.47 0.68 1 34 76 109 34 0 0 153 Q6RYB6 Proglucagon (Fragment) OS=Protopterus dolloi PE=2 SV=1
54 : Q8UWL9_9NEOB 0.47 0.69 1 36 135 170 36 0 0 220 Q8UWL9 Proglucagon OS=Hoplobatrachus rugulosus PE=2 SV=1
55 : S7P0P8_MYOBR 0.47 0.63 1 38 128 165 38 0 0 207 S7P0P8 Glucagon OS=Myotis brandtii GN=D623_10035573 PE=3 SV=1
56 : T0MG31_9CETA 0.47 0.67 1 36 82 117 36 0 0 163 T0MG31 Glucagon-like protein OS=Camelus ferus GN=CB1_000290027 PE=3 SV=1
57 : U6CR11_NEOVI 0.47 0.67 1 36 98 133 36 0 0 180 U6CR11 Glucagon OS=Neovison vison GN=GLUC PE=2 SV=1
58 : W5P8Q7_SHEEP 0.47 0.67 1 36 98 133 36 0 0 180 W5P8Q7 Glucagon OS=Ovis aries GN=GCG PE=4 SV=1
59 : G1PDQ8_MYOLU 0.46 0.63 1 35 103 137 35 0 0 182 G1PDQ8 Uncharacterized protein OS=Myotis lucifugus PE=3 SV=1
60 : GLUC_CHICK 0.44 0.67 1 36 118 153 36 0 0 206 P68259 Glucagon OS=Gallus gallus GN=GCG PE=1 SV=1
61 : H0Z908_TAEGU 0.44 0.67 1 36 118 153 36 0 0 201 H0Z908 Uncharacterized protein OS=Taeniopygia guttata GN=GCG PE=3 SV=1
62 : K7SA47_ALLSI 0.44 0.67 1 36 118 153 36 0 0 206 K7SA47 Glucagon OS=Alligator sinensis PE=2 SV=1
63 : Q3HLJ1_MELGA 0.44 0.67 1 36 118 153 36 0 0 206 Q3HLJ1 Glucagon (Precursor) OS=Meleagris gallopavo GN=GCG PE=2 SV=1
64 : Q3HWX0_CHICK 0.44 0.67 1 36 118 153 36 0 0 206 Q3HWX0 Preproglucagon B (Precursor) OS=Gallus gallus GN=GCG PE=2 SV=1
65 : R0JGN8_ANAPL 0.44 0.67 1 36 118 153 36 0 0 201 R0JGN8 Glucagon (Fragment) OS=Anas platyrhynchos GN=Anapl_07609 PE=3 SV=1
66 : U3IS24_ANAPL 0.44 0.67 1 36 118 153 36 0 0 207 U3IS24 Uncharacterized protein OS=Anas platyrhynchos PE=3 SV=1
67 : U3JD74_FICAL 0.44 0.67 1 36 118 153 36 0 0 206 U3JD74 Uncharacterized protein OS=Ficedula albicollis GN=GCG PE=3 SV=1
68 : GLUC_LITCT 0.43 0.70 1 37 39 75 37 0 0 103 P15438 Glucagon (Fragments) OS=Lithobates catesbeiana GN=gcg PE=1 SV=2
## ALIGNMENTS 1 - 68
SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
1 1 A H 0 0 265 69 0 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
2 2 A G + 0 0 76 69 26 GGSAAAAAAAAAAAAAASAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAAAAAAAAAAAA
3 3 A E + 0 0 191 69 10 EEDDEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEED
4 4 A G > + 0 0 45 69 0 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
5 5 A T T 3 + 0 0 120 69 0 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
6 6 A F T 3> + 0 0 130 69 2 FFFYFYFFFFFFFFFFFFFFFFFFFFFFFFFFFYFFFFFYFFFFFFFFFFFFYFFFFFFYYYYYYYYF
7 7 A T H <> S+ 0 0 86 69 0 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
8 8 A S H > S+ 0 0 94 69 4 SSSSNSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS
9 9 A D H > S+ 0 0 107 69 0 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
10 10 A L H X S+ 0 0 76 69 36 LLLIMVMVVVVVVVVVVLVVVVVVVVVVVVVVVIVVVVVVVVVVVVVVVVVVIMLVVVIIIIIIIIIM
11 11 A S H X S+ 0 0 88 69 28 SSSSTSTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSSSSSTTTTTTTTS
12 12 A K H X S+ 0 0 149 69 43 KKKANSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSASSSSSSSSSSSSSSSSSSSSSSSSSSSS
13 13 A Q H X S+ 0 0 118 69 48 QQQYYYFYYYYYYYYYYYYYYYYYYYYYYYYYYFYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYY
14 14 A M H X S+ 0 0 135 69 4 MMMLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
15 15 A E H X S+ 0 0 132 69 16 EEEQEQEEEEEEEEEEEEEEEEEEEEEEEEEEEREEEEEQEEEEEEEEEEEEEEEEEEEEEEEEEEEE
16 16 A E H X S+ 0 0 99 69 46 EEEDEEEGGGGGGGGGGGGGGGGGGGGGGGGGGDGGGGGDGGGGGGGGGGGGGEGGGGGGGGGGGGGE
17 17 A E H X S+ 0 0 95 69 39 EEEQKQKQQQQQQQQQQKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQQQQQQQQQK
18 18 A A H X S+ 0 0 41 69 0 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
19 19 A V H X S+ 0 0 68 69 38 VVVAAAAAAAAAAAAAATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAVATAAAAAAAAAAAAA
20 20 A R H X S+ 0 0 170 69 23 RRRKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKQKKKKKKKKKKKKKKKKKKNKKKKKKKKKKKKKKK
21 21 A L H X S+ 0 0 86 69 51 LLLDEDEEEEEEEEEEEEEEEEEEEEEEEEEEENEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEE
22 22 A F H X S+ 0 0 90 69 0 FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
23 23 A I H X S+ 0 0 85 69 7 IIIIVIVIIIIIIIIIIIIIIIIIIIIIIIIIIVIIIIIIIIIIIIIIIIIIIVIIIIIIIIIIIIIV
24 24 A E H X S+ 0 0 140 69 57 EEETGTDAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATAAAAAAAAAAAARDAAAAAAAAAAAAAD
25 25 A W H <>S+ 0 0 22 69 0 WWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWW
26 26 A L H ><5S+ 0 0 80 69 0 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
27 27 A K H 3<5S+ 0 0 182 69 69 KKKKIKIVVVVVVVVVVVVVVVVVVVVVVVVVVKVVVVVKVVVVVVVVVVVVMIVVVVVVVVVVVVVI
28 28 A N T 3<5S- 0 0 84 69 54 NNNNNSKKKKKKKKKKKKKKKKKKKKKKKKKKKSKKKKKSKKKKKKKKKKKKKKKKKKKNNNNNNNNK
29 29 A G T X 5 - 0 0 30 69 0 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
30 30 A G G >