Complet list of 1h7j hssp file
Complete list of 1h7j.hssp file
HSSP HOMOLOGY DERIVED SECONDARY STRUCTURE OF PROTEINS , VERSION 2.0 2011
PDBID 1H7J
THRESHOLD according to: t(L)=(290.15 * L ** -0.562) + 5
REFERENCE Sander C., Schneider R. : Database of homology-derived protein structures. Proteins, 9:56-68 (1991).
CONTACT Maintained at http://www.cmbi.ru.nl/ by Maarten L. Hekkelman
DATE file generated on 2014-04-30
HEADER ACYLTRANSFERASE 08-JUL-01 1H7J
COMPND MOL_ID: 1; MOLECULE: AMINOLEVULINIC ACID SYNTHASE 2, ERYTHROID; CHAIN:
SOURCE MOL_ID: 1; SYNTHETIC: YES; ORGANISM_SCIENTIFIC: MUS MUSCULUS; ORGANISM
AUTHOR B.J.GOODFELLOW,J.S.DIAS,G.C.FERREIRA,V.WRAY,P.HENKLEIN, A.L.MACEDO
DBREF 1H7J A 1 26 UNP Q64452 Q64452 1 26
SEQLENGTH 26
NCHAIN 1 chain(s) in 1H7J data set
NALIGN 44
NOTATION : ID: EMBL/SWISSPROT identifier of the aligned (homologous) protein
NOTATION : STRID: if the 3-D structure of the aligned protein is known, then STRID is the Protein Data Bank identifier as taken
NOTATION : from the database reference or DR-line of the EMBL/SWISSPROT entry
NOTATION : %IDE: percentage of residue identity of the alignment
NOTATION : %SIM (%WSIM): (weighted) similarity of the alignment
NOTATION : IFIR/ILAS: first and last residue of the alignment in the test sequence
NOTATION : JFIR/JLAS: first and last residue of the alignment in the alignend protein
NOTATION : LALI: length of the alignment excluding insertions and deletions
NOTATION : NGAP: number of insertions and deletions in the alignment
NOTATION : LGAP: total length of all insertions and deletions
NOTATION : LSEQ2: length of the entire sequence of the aligned protein
NOTATION : ACCNUM: SwissProt accession number
NOTATION : PROTEIN: one-line description of aligned protein
NOTATION : SeqNo,PDBNo,AA,STRUCTURE,BP1,BP2,ACC: sequential and PDB residue numbers, amino acid (lower case = Cys), secondary
NOTATION : structure, bridge partners, solvent exposure as in DSSP (Kabsch and Sander, Biopolymers 22, 2577-2637(1983)
NOTATION : VAR: sequence variability on a scale of 0-100 as derived from the NALIGN alignments
NOTATION : pair of lower case characters (AvaK) in the alignend sequence bracket a point of insertion in this sequence
NOTATION : dots (....) in the alignend sequence indicate points of deletion in this sequence
NOTATION : SEQUENCE PROFILE: relative frequency of an amino acid type at each position. Asx and Glx are in their
NOTATION : acid/amide form in proportion to their database frequencies
NOTATION : NOCC: number of aligned sequences spanning this position (including the test sequence)
NOTATION : NDEL: number of sequences with a deletion in the test protein at this position
NOTATION : NINS: number of sequences with an insertion in the test protein at this position
NOTATION : ENTROPY: entropy measure of sequence variability at this position
NOTATION : RELENT: relative entropy, i.e. entropy normalized to the range 0-100
NOTATION : WEIGHT: conservation weight
## PROTEINS : identifier and alignment statistics
NR. ID STRID %IDE %WSIM IFIR ILAS JFIR JLAS LALI NGAP LGAP LSEQ2 ACCNUM PROTEIN
1 : A2AFM0_MOUSE 1.00 1.00 1 26 1 26 26 0 0 587 A2AFM0 5-aminolevulinate synthase OS=Mus musculus GN=Alas2 PE=2 SV=1
2 : A2AFM1_MOUSE 1.00 1.00 1 26 1 26 26 0 0 572 A2AFM1 5-aminolevulinate synthase OS=Mus musculus GN=Alas2 PE=2 SV=1
3 : HEM0_MOUSE 1.00 1.00 1 26 1 26 26 0 0 587 P08680 5-aminolevulinate synthase, erythroid-specific, mitochondrial OS=Mus musculus GN=Alas2 PE=1 SV=3
4 : Q3TA47_MOUSE 1.00 1.00 1 26 1 26 26 0 0 587 Q3TA47 5-aminolevulinate synthase OS=Mus musculus GN=Alas2 PE=2 SV=1
5 : Q3TNI1_MOUSE 1.00 1.00 1 26 1 26 26 0 0 587 Q3TNI1 5-aminolevulinate synthase OS=Mus musculus GN=Alas2 PE=2 SV=1
6 : HEM0_RAT 0.96 1.00 1 26 1 26 26 0 0 587 Q63147 5-aminolevulinate synthase, erythroid-specific, mitochondrial OS=Rattus norvegicus GN=Alas2 PE=1 SV=1
7 : Q642C1_RAT 0.96 1.00 1 26 1 26 26 0 0 587 Q642C1 5-aminolevulinate synthase OS=Rattus norvegicus GN=Alas2 PE=2 SV=1
8 : Q9ESE3_RAT 0.96 1.00 1 26 1 26 26 0 0 164 Q9ESE3 5-aminolevulinate synthase (Fragment) OS=Rattus norvegicus GN=Alas2 PE=2 SV=1
9 : K7WED4_MESAU 0.90 1.00 6 26 1 21 21 0 0 241 K7WED4 5-aminolevulinic acid synthase 2 (Fragment) OS=Mesocricetus auratus GN=ALAS2 PE=2 SV=1
10 : L5KXS8_PTEAL 0.84 0.92 1 25 1 25 25 0 0 573 L5KXS8 5-aminolevulinate synthase OS=Pteropus alecto GN=PAL_GLEAN10000459 PE=3 SV=1
11 : G1T5R2_RABIT 0.81 0.92 1 26 1 26 26 0 0 587 G1T5R2 5-aminolevulinate synthase OS=Oryctolagus cuniculus GN=ALAS2 PE=3 SV=1
12 : U3KN65_RABIT 0.81 0.92 1 26 7 32 26 0 0 601 U3KN65 5-aminolevulinate synthase OS=Oryctolagus cuniculus GN=ALAS2 PE=3 SV=1
13 : F1RUD4_PIG 0.80 0.92 1 25 1 25 25 0 0 587 F1RUD4 5-aminolevulinate synthase OS=Sus scrofa GN=ALAS2 PE=3 SV=2
14 : G5B8F5_HETGA 0.80 0.92 1 25 1 25 25 0 0 586 G5B8F5 5-aminolevulinate synthase OS=Heterocephalus glaber GN=GW7_11797 PE=3 SV=1
15 : H0WX32_OTOGA 0.80 0.96 1 25 1 25 25 0 0 587 H0WX32 5-aminolevulinate synthase OS=Otolemur garnettii GN=ALAS2 PE=3 SV=1
16 : K7GR18_PIG 0.80 0.92 1 25 1 25 25 0 0 550 K7GR18 5-aminolevulinate synthase OS=Sus scrofa GN=ALAS2 PE=3 SV=1
17 : F6VBB6_MACMU 0.76 0.96 1 25 24 48 25 0 0 573 F6VBB6 5-aminolevulinate synthase OS=Macaca mulatta GN=ALAS2 PE=3 SV=1
18 : F6VBC4_MACMU 0.76 0.96 1 25 1 25 25 0 0 587 F6VBC4 5-aminolevulinate synthase OS=Macaca mulatta GN=ALAS2 PE=3 SV=1
19 : F6VBD2_MACMU 0.76 0.96 1 25 1 25 25 0 0 550 F6VBD2 5-aminolevulinate synthase OS=Macaca mulatta GN=ALAS2 PE=3 SV=1
20 : F6YP89_CALJA 0.76 0.96 1 25 1 25 25 0 0 587 F6YP89 5-aminolevulinate synthase OS=Callithrix jacchus GN=ALAS2 PE=3 SV=1
21 : F6Z7S6_CALJA 0.76 0.96 1 25 25 49 25 0 0 574 F6Z7S6 5-aminolevulinate synthase OS=Callithrix jacchus GN=ALAS2 PE=3 SV=1
22 : G1S2R3_NOMLE 0.76 0.96 1 25 1 25 25 0 0 585 G1S2R3 5-aminolevulinate synthase OS=Nomascus leucogenys GN=ALAS2 PE=3 SV=1
23 : G3QI29_GORGO 0.76 0.96 1 25 1 25 25 0 0 587 G3QI29 5-aminolevulinate synthase OS=Gorilla gorilla gorilla GN=101141780 PE=3 SV=1
24 : G3TS41_LOXAF 0.76 0.88 1 25 1 25 25 0 0 588 G3TS41 5-aminolevulinate synthase OS=Loxodonta africana GN=ALAS2 PE=3 SV=1
25 : G3UDF4_LOXAF 0.76 0.88 1 25 1 25 25 0 0 587 G3UDF4 5-aminolevulinate synthase OS=Loxodonta africana GN=ALAS2 PE=3 SV=1
26 : G7Q2U5_MACFA 0.76 0.96 1 25 1 25 25 0 0 587 G7Q2U5 5-aminolevulinate synthase OS=Macaca fascicularis GN=EGM_18821 PE=3 SV=1
27 : H2PVS3_PONAB 0.76 0.96 1 25 25 49 25 0 0 571 H2PVS3 5-aminolevulinate synthase OS=Pongo abelii GN=ALAS2 PE=3 SV=1
28 : H9GZN2_HORSE 0.76 0.96 1 25 1 25 25 0 0 587 H9GZN2 5-aminolevulinate synthase OS=Equus caballus GN=ALAS2 PE=3 SV=1
29 : HEM0_HUMAN 0.76 0.96 1 25 1 25 25 0 0 587 P22557 5-aminolevulinate synthase, erythroid-specific, mitochondrial OS=Homo sapiens GN=ALAS2 PE=1 SV=2
30 : I3MAT7_SPETR 0.76 0.96 1 25 1 25 25 0 0 587 I3MAT7 5-aminolevulinate synthase OS=Spermophilus tridecemlineatus GN=ALAS2 PE=3 SV=1
31 : Q6QNT2_HUMAN 0.76 0.96 1 25 1 25 25 0 0 101 Q6QNT2 5-aminoevulinate synthase 2 (Fragment) OS=Homo sapiens GN=ALAS2 PE=2 SV=1
32 : S9W7E2_9CETA 0.76 0.92 1 25 1 25 25 0 0 587 S9W7E2 5-aminolevulinate synthase OS=Camelus ferus GN=CB1_002327002 PE=3 SV=1
33 : L8IP19_9CETA 0.75 0.92 1 24 1 24 24 0 0 587 L8IP19 5-aminolevulinate synthase OS=Bos mutus GN=M91_20482 PE=3 SV=1
34 : D2I6H8_AILME 0.72 0.88 1 25 1 25 25 0 0 275 D2I6H8 Putative uncharacterized protein (Fragment) OS=Ailuropoda melanoleuca GN=PANDA_021429 PE=4 SV=1
35 : H0V9P7_CAVPO 0.72 0.84 1 25 1 25 25 0 0 587 H0V9P7 5-aminolevulinate synthase OS=Cavia porcellus GN=ALAS2 PE=3 SV=1
36 : HEM0_BOVIN 0.72 0.92 1 25 1 25 25 0 0 587 Q3ZC31 5-aminolevulinate synthase, erythroid-specific, mitochondrial OS=Bos taurus GN=ALAS2 PE=2 SV=1
37 : HEM0_PONAB 0.72 0.92 1 25 1 25 25 0 0 587 Q5R557 5-aminolevulinate synthase, erythroid-specific, mitochondrial OS=Pongo abelii GN=ALAS2 PE=1 SV=1
38 : M3XW20_MUSPF 0.72 0.88 1 25 1 25 25 0 0 586 M3XW20 5-aminolevulinate synthase OS=Mustela putorius furo PE=2 SV=1
39 : U6CPU0_NEOVI 0.72 0.88 1 25 1 25 25 0 0 586 U6CPU0 5-aminolevulinate synthase OS=Neovison vison GN=HEM0 PE=2 SV=1
40 : W5P6N1_SHEEP 0.72 0.92 1 25 1 25 25 0 0 587 W5P6N1 Uncharacterized protein OS=Ovis aries GN=ALAS2 PE=4 SV=1
41 : M3VVM0_FELCA 0.68 0.84 1 25 1 25 25 0 0 587 M3VVM0 5-aminolevulinate synthase OS=Felis catus GN=ALAS2 PE=3 SV=1
42 : G1PUA8_MYOLU 0.64 0.88 1 25 1 25 25 0 0 586 G1PUA8 5-aminolevulinate synthase OS=Myotis lucifugus GN=ALAS2 PE=3 SV=1
43 : L5LRH4_MYODS 0.64 0.88 1 25 66 90 25 0 0 615 L5LRH4 5-aminolevulinate synthase OS=Myotis davidii GN=MDA_GLEAN10003981 PE=3 SV=1
44 : S7MLN0_MYOBR 0.64 0.88 1 25 22 46 25 0 0 571 S7MLN0 5-aminolevulinate synthase OS=Myotis brandtii GN=D623_10008212 PE=3 SV=1
## ALIGNMENTS 1 - 44
SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
1 1 A M 0 0 244 44 0 MMMMMMMM MMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMM
2 2 A V + 0 0 131 44 2 VVVVVVVV VVVVVMVVVVVVVVVVVVVVVVVVVVVVVVVVVVV
3 3 A A + 0 0 37 44 37 AAAAAAAA AAAAAAATTTTTTTAATTATATATAATTAATAAAA
4 4 A A S > S+ 0 0 76 44 15 AAAAAAAA AAAAAAAAAAAAAAVVAAAAAAAAAIAAAAAAAAA
5 5 A A T 4 S+ 0 0 75 44 21 AAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAVVVV
6 6 A M T >4 S+ 0 0 135 45 12 MMMMMMMMMMMMMMMMMMMMMMMLLMMIMVMMMMTMMMMMMMMM
7 7 A L T 34 S+ 0 0 130 45 0 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
8 8 A L T 3< S+ 0 0 116 45 0 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
9 9 A R S < S- 0 0 187 45 37 RRRRRRRRRQRRQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQQQ
10 10 A S S S+ 0 0 92 45 67 SSSSSSSSSCCCRCYRCCCCCCCCCCCRCCCRRCYRCCCRCRRR
11 11 A C + 0 0 106 45 0 CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
12 12 A P + 0 0 95 45 0 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP
13 13 A V + 0 0 100 45 0 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVV
14 14 A L S S+ 0 0 151 45 10 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLPLLLFFFF
15 15 A S S S+ 0 0 78 45 56 SSSSSSSSSAAAIAAIAAAAAAASSAAAAAAIIAAIAAAISAAA
16 16 A Q S S+ 0 0 198 45 32 QQQQQKKKRQQQRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRR
17 17 A G + 0 0 42 45 22 GGGGGGGGGGSSGTGGGGGGGGGGGGGGGGGSSGTSGGGSGGGG
18 18 A P - 0 0 127 45 28 PPPPPPPPPPPPPPPPPPPPPPPLLPPPPPPPPHPPPHHPHPPP
19 19 A T - 0 0 109 45 24 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTITTTTTTISSS
20 20 A G + 0 0 71 45 25 GGGGGGGGGGGGGGGGSSSSSSSGGSSGSGSGGGGGSGGGGGGG
21 21 A L + 0 0 98 45 34 LLLLLLLLLLLLLLLLLLLLLLLLLLLILLLLLLLLLPPLLPPP
22 22 A L S S+ 0 0 167 45 2 LLLLLLLLVLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
23 23 A G S S+ 0 0 84 45 17 GGGGGGGGGNRRGGGGGGGGGGGGGGGGGSGGGGGGGGGGGGGG
24 24 A K + 0 0 152 45 0 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
25 25 A V 0 0 103 44 28 VVVVVVVVVVVVMVVMVVVVVVVVVVVVVVVM MVMVMMMMLLL
26 26 A A 0 0 141 12 54 AAAAAAAAA TT
## SEQUENCE PROFILE AND ENTROPY
SeqNo PDBNo V L I M F W Y G A P S T C H R K Q E N D NOCC NDEL NINS ENTROPY RELENT WEIGHT
1 1 A 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 44 0 0 0.000 0 1.00
2 2 A 98 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 44 0 0 0.108 3 0.97
3 3 A 0 0 0 0 0 0 0 0 66 0 0 34 0 0 0 0 0 0 0 0 44 0 0 0.642 21 0.63
4 4 A 5 0 2 0 0 0 0 0 93 0 0 0 0 0 0 0 0 0 0 0 44 0 0 0.292 9 0.85
5 5 A 9 0 0 0 0 0 0 0 91 0 0 0 0 0 0 0 0 0 0 0 44 0 0 0.305 10 0.78
6 6 A 2 4 2 89 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 45 0 0 0.497 16 0.88
7 7 A 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45 0 0 0.000 0 1.00
8 8 A 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45 0 0 0.000 0 1.00
9 9 A 0 0 0 0 0 0 0 0 0 0 0 0 0 2 27 0 71 0 0 0 45 0 0 0.679 22 0.62
10 10 A 0 0 0 0 0 0 4 0 0 0 22 0 51 0 22 0 0 0 0 0 45 0 0 1.150 38 0.33
11 11 A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 45 0 0 0.000 0 1.00
12 12 A 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 45 0 0 0.000 0 1.00
13 13 A 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45 0 0 0.000 0 1.00
14 14 A 0 89 0 0 9 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 45 0 0 0.404 13 0.90
15 15 A 0 0 13 0 0 0 0 0 58 0 29 0 0 0 0 0 0 0 0 0 45 0 0 0.944 31 0.43
16 16 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 73 7 20 0 0 0 45 0 0 0.730 24 0.68
17 17 A 0 0 0 0 0 0 0 82 0 0 13 4 0 0 0 0 0 0 0 0 45 0 0 0.568 18 0.78
18 18 A 0 4 0 0 0 0 0 0 0 87 0 0 0 9 0 0 0 0 0 0 45 0 0 0.478 15 0.71
19 19 A 0 0 4 0 0 0 0 0 0 0 7 89 0 0 0 0 0 0 0 0 45 0 0 0.424 14 0.76
20 20 A 0 0 0 0 0 0 0 73 0 0 27 0 0 0 0 0 0 0 0 0 45 0 0 0.580 19 0.74
21 21 A 0 87 2 0 0 0 0 0 0 11 0 0 0 0 0 0 0 0 0 0 45 0 0 0.453 15 0.66
22 22 A 2 98 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45 0 0 0.107 3 0.98
23 23 A 0 0 0 0 0 0 0 91 0 0 2 0 0 0 4 0 0 0 2 0 45 0 0 0.392 13 0.82
24 24 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 45 0 0 0.000 0 1.00
25 25 A 73 7 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 44 0 0 0.739 24 0.71
26 26 A 0 0 0 0 0 0 0 0 83 0 0 17 0 0 0 0 0 0 0 0 12 0 0 0.451 15 0.46
## INSERTION LIST
AliNo IPOS JPOS Len Sequence
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