Complet list of 1dgn hssp file
Complete list of 1dgn.hssp file
HSSP HOMOLOGY DERIVED SECONDARY STRUCTURE OF PROTEINS , VERSION 2.0 2011
PDBID 1DGN
THRESHOLD according to: t(L)=(290.15 * L ** -0.562) + 5
REFERENCE Sander C., Schneider R. : Database of homology-derived protein structures. Proteins, 9:56-68 (1991).
CONTACT Maintained at http://www.cmbi.ru.nl/ by Maarten L. Hekkelman
DATE file generated on 2014-04-27
HEADER HYDROLASE INHIBITOR 24-NOV-99 1DGN
COMPND MOL_ID: 1; MOLECULE: ICEBERG (PROTEASE INHIBITOR); CHAIN: A; FRAGMENT:
SOURCE MOL_ID: 1; ORGANISM_SCIENTIFIC: HOMO SAPIENS; ORGANISM_COMMON: HUMAN;
AUTHOR E.W.HUMKE,S.K.SHRIVER,M.A.STAROVASNIK,W.J.FAIRBROTHER, V.M.DIXIT
DBREF 1DGN A 2 90 UNP P57730 ICBR_HUMAN 2 90
SEQLENGTH 89
NCHAIN 1 chain(s) in 1DGN data set
NALIGN 157
NOTATION : ID: EMBL/SWISSPROT identifier of the aligned (homologous) protein
NOTATION : STRID: if the 3-D structure of the aligned protein is known, then STRID is the Protein Data Bank identifier as taken
NOTATION : from the database reference or DR-line of the EMBL/SWISSPROT entry
NOTATION : %IDE: percentage of residue identity of the alignment
NOTATION : %SIM (%WSIM): (weighted) similarity of the alignment
NOTATION : IFIR/ILAS: first and last residue of the alignment in the test sequence
NOTATION : JFIR/JLAS: first and last residue of the alignment in the alignend protein
NOTATION : LALI: length of the alignment excluding insertions and deletions
NOTATION : NGAP: number of insertions and deletions in the alignment
NOTATION : LGAP: total length of all insertions and deletions
NOTATION : LSEQ2: length of the entire sequence of the aligned protein
NOTATION : ACCNUM: SwissProt accession number
NOTATION : PROTEIN: one-line description of aligned protein
NOTATION : SeqNo,PDBNo,AA,STRUCTURE,BP1,BP2,ACC: sequential and PDB residue numbers, amino acid (lower case = Cys), secondary
NOTATION : structure, bridge partners, solvent exposure as in DSSP (Kabsch and Sander, Biopolymers 22, 2577-2637(1983)
NOTATION : VAR: sequence variability on a scale of 0-100 as derived from the NALIGN alignments
NOTATION : pair of lower case characters (AvaK) in the alignend sequence bracket a point of insertion in this sequence
NOTATION : dots (....) in the alignend sequence indicate points of deletion in this sequence
NOTATION : SEQUENCE PROFILE: relative frequency of an amino acid type at each position. Asx and Glx are in their
NOTATION : acid/amide form in proportion to their database frequencies
NOTATION : NOCC: number of aligned sequences spanning this position (including the test sequence)
NOTATION : NDEL: number of sequences with a deletion in the test protein at this position
NOTATION : NINS: number of sequences with an insertion in the test protein at this position
NOTATION : ENTROPY: entropy measure of sequence variability at this position
NOTATION : RELENT: relative entropy, i.e. entropy normalized to the range 0-100
NOTATION : WEIGHT: conservation weight
## PROTEINS : identifier and alignment statistics
NR. ID STRID %IDE %WSIM IFIR ILAS JFIR JLAS LALI NGAP LGAP LSEQ2 ACCNUM PROTEIN
1 : CAR18_HUMAN 1.00 1.00 1 89 2 90 89 0 0 90 P57730 Caspase recruitment domain-containing protein 18 OS=Homo sapiens GN=CARD18 PE=1 SV=1
2 : G3QKS6_GORGO 0.98 0.99 2 88 1 87 87 0 0 88 G3QKS6 Uncharacterized protein (Fragment) OS=Gorilla gorilla gorilla GN=101139631 PE=4 SV=1
3 : H2NF49_PONAB 0.98 1.00 1 89 1 89 89 0 0 89 H2NF49 Uncharacterized protein (Fragment) OS=Pongo abelii GN=CARD18 PE=4 SV=1
4 : G7NBS4_MACMU 0.93 0.97 2 89 1 88 88 0 0 88 G7NBS4 Putative uncharacterized protein (Fragment) OS=Macaca mulatta GN=EGK_06845 PE=4 SV=1
5 : G7PNL8_MACFA 0.93 0.97 2 89 1 88 88 0 0 88 G7PNL8 Putative uncharacterized protein (Fragment) OS=Macaca fascicularis GN=EGM_06178 PE=4 SV=1
6 : F7I702_CALJA 0.90 0.93 2 89 1 88 88 0 0 89 F7I702 Uncharacterized protein (Fragment) OS=Callithrix jacchus GN=CARD18 PE=4 SV=1
7 : CASP1_HORSE 0.62 0.83 1 88 2 89 88 0 0 405 Q9TV13 Caspase-1 OS=Equus caballus GN=CASP1 PE=2 SV=1
8 : L5LXX3_MYODS 0.62 0.77 11 88 2 79 78 0 0 137 L5LXX3 Caspase-1 OS=Myotis davidii GN=MDA_GLEAN10000825 PE=4 SV=1
9 : L8J304_9CETA 0.62 0.85 2 88 1 87 87 0 0 401 L8J304 Caspase (Fragment) OS=Bos mutus GN=M91_05575 PE=3 SV=1
10 : A0PCH9_BOVIN 0.61 0.83 7 88 1 82 82 0 0 389 A0PCH9 Caspase (Fragment) OS=Bos taurus GN=Casp1 PE=2 SV=1
11 : F6X8D2_HORSE 0.60 0.83 1 88 1 88 88 0 0 404 F6X8D2 Caspase (Fragment) OS=Equus caballus GN=CASP1 PE=3 SV=1
12 : K0GM06_BUBBU 0.60 0.82 1 88 2 89 88 0 0 402 K0GM06 Caspase (Fragment) OS=Bubalus bubalis PE=2 SV=1
13 : G1L0X5_AILME 0.59 0.78 1 88 2 89 88 0 0 486 G1L0X5 Uncharacterized protein (Fragment) OS=Ailuropoda melanoleuca GN=LOC100464921 PE=3 SV=1
14 : G1P9W7_MYOLU 0.59 0.77 1 88 2 89 88 0 0 404 G1P9W7 Caspase (Fragment) OS=Myotis lucifugus GN=CASP1 PE=3 SV=1
15 : H0WSC0_OTOGA 0.59 0.80 1 88 2 89 88 0 0 483 H0WSC0 Uncharacterized protein (Fragment) OS=Otolemur garnettii PE=3 SV=1
16 : I3MAR6_SPETR 0.59 0.77 1 88 2 89 88 0 0 404 I3MAR6 Caspase (Fragment) OS=Spermophilus tridecemlineatus GN=CASP1 PE=3 SV=1
17 : I3MU55_SPETR 0.59 0.77 1 88 2 89 88 0 0 410 I3MU55 Caspase (Fragment) OS=Spermophilus tridecemlineatus GN=CASP1 PE=3 SV=1
18 : S7MDX5_MYOBR 0.59 0.79 2 88 77 163 87 0 0 1097 S7MDX5 Caspase-1 OS=Myotis brandtii GN=D623_10033743 PE=3 SV=1
19 : S9XY06_9CETA 0.59 0.83 1 88 2 89 88 0 0 600 S9XY06 Caspase-1 isoform 1 OS=Camelus ferus GN=CB1_000877038 PE=3 SV=1
20 : A9YEF3_FELCA 0.58 0.80 1 88 2 89 88 0 0 495 A9YEF3 Caspase-1/caspase-4 hybrid OS=Felis catus PE=2 SV=1
21 : CASP1_FELCA 0.58 0.81 1 88 2 89 88 0 0 410 Q9MZV6 Caspase-1 OS=Felis catus GN=CASP1 PE=2 SV=1
22 : F6SFY2_CALJA 0.57 0.81 1 88 2 89 88 0 0 97 F6SFY2 Uncharacterized protein OS=Callithrix jacchus GN=CASP1 PE=4 SV=1
23 : G1Q520_MYOLU 0.57 0.76 1 88 1 88 88 0 0 369 G1Q520 Caspase (Fragment) OS=Myotis lucifugus PE=3 SV=1
24 : G1SER4_RABIT 0.57 0.82 1 88 17 104 88 0 0 418 G1SER4 Caspase OS=Oryctolagus cuniculus GN=CASP1 PE=3 SV=2
25 : M3W4Y9_FELCA 0.57 0.80 1 88 2 89 88 0 0 495 M3W4Y9 Caspase-1 (Fragment) OS=Felis catus GN=CASP1 PE=3 SV=1
26 : M3WZA6_FELCA 0.57 0.80 1 88 2 89 88 0 0 410 M3WZA6 Caspase (Fragment) OS=Felis catus GN=CASP1 PE=3 SV=1
27 : W5NYL2_SHEEP 0.57 0.84 1 88 2 89 88 0 0 403 W5NYL2 Uncharacterized protein OS=Ovis aries GN=LOC101117013 PE=4 SV=1
28 : CAR16_HUMAN 0.56 0.78 1 88 2 89 88 0 0 197 Q5EG05 Caspase recruitment domain-containing protein 16 OS=Homo sapiens GN=CARD16 PE=1 SV=1
29 : CASP1_PIG 0.56 0.81 1 88 2 89 88 0 0 404 Q9N2I1 Caspase-1 OS=Sus scrofa GN=CASP1 PE=2 SV=1
30 : F6ZE88_CALJA 0.56 0.81 1 88 1 88 88 0 0 402 F6ZE88 Caspase (Fragment) OS=Callithrix jacchus GN=CASP1 PE=3 SV=1
31 : F7F5A7_CALJA 0.56 0.81 1 88 1 88 88 0 0 197 F7F5A7 Uncharacterized protein (Fragment) OS=Callithrix jacchus GN=CASP1 PE=4 SV=1
32 : F7FJ70_CALJA 0.56 0.80 2 88 1 87 87 0 0 108 F7FJ70 Uncharacterized protein (Fragment) OS=Callithrix jacchus GN=CASP1 PE=4 SV=1
33 : F7FJB9_CALJA 0.56 0.80 1 88 1 88 88 0 0 399 F7FJB9 Caspase (Fragment) OS=Callithrix jacchus GN=CASP1 PE=3 SV=1
34 : F7FXF1_CALJA 0.56 0.80 2 88 1 87 87 0 0 381 F7FXF1 Caspase (Fragment) OS=Callithrix jacchus GN=CASP1 PE=3 SV=1
35 : G1R6G1_NOMLE 0.56 0.78 1 88 60 147 88 0 0 462 G1R6G1 Uncharacterized protein OS=Nomascus leucogenys GN=CASP1 PE=3 SV=2
36 : H2R501_PANTR 0.56 0.78 1 88 2 89 88 0 0 91 H2R501 Uncharacterized protein OS=Pan troglodytes GN=CARD16 PE=4 SV=1
37 : I3LIL3_PIG 0.56 0.81 1 88 2 89 88 0 0 404 I3LIL3 Caspase OS=Sus scrofa GN=CASP1 PE=3 SV=1
38 : W5NYL5_SHEEP 0.56 0.84 1 88 2 89 88 0 0 486 W5NYL5 Uncharacterized protein (Fragment) OS=Ovis aries GN=LOC101117013 PE=4 SV=1
39 : CAR17_HUMAN 0.55 0.77 1 88 2 89 88 0 0 110 Q5XLA6 Caspase recruitment domain-containing protein 17 OS=Homo sapiens GN=CARD17 PE=1 SV=1
40 : E9PQW1_HUMAN 0.55 0.75 16 88 1 73 73 0 0 95 E9PQW1 Caspase recruitment domain-containing protein 16 (Fragment) OS=Homo sapiens GN=CARD16 PE=2 SV=1
41 : F6YZS8_MACMU 0.55 0.75 16 88 1 73 73 0 0 94 F6YZS8 Uncharacterized protein OS=Macaca mulatta GN=LOC706971 PE=4 SV=1
42 : G3QIA6_GORGO 0.55 0.80 1 88 2 89 88 0 0 197 G3QIA6 Uncharacterized protein OS=Gorilla gorilla gorilla GN=101138158 PE=4 SV=1
43 : H2Q4N8_PANTR 0.55 0.76 1 88 2 88 88 1 1 90 H2Q4N8 Uncharacterized protein OS=Pan troglodytes PE=4 SV=1
44 : H2RCJ2_PANTR 0.55 0.75 1 88 2 89 88 0 0 91 H2RCJ2 Uncharacterized protein OS=Pan troglodytes PE=4 SV=1
45 : L5KYI5_PTEAL 0.55 0.78 4 88 2 86 85 0 0 682 L5KYI5 Caspase-13 OS=Pteropus alecto GN=PAL_GLEAN10013832 PE=4 SV=1
46 : A8K249_HUMAN 0.53 0.80 1 88 2 89 88 0 0 404 A8K249 Caspase OS=Homo sapiens PE=2 SV=1
47 : A8K257_HUMAN 0.53 0.80 1 88 2 89 88 0 0 383 A8K257 Caspase OS=Homo sapiens PE=2 SV=1
48 : A9YEF4_CANFA 0.53 0.81 1 88 2 89 88 0 0 489 A9YEF4 Caspase-1/caspase-4 hybrid OS=Canis familiaris PE=2 SV=1
49 : B2R8U9_HUMAN 0.53 0.80 1 88 2 89 88 0 0 404 B2R8U9 Caspase OS=Homo sapiens PE=2 SV=1
50 : B4DKN4_HUMAN 0.53 0.80 1 88 2 89 88 0 0 162 B4DKN4 cDNA FLJ58540, highly similar to Caspase-1 (EC 3.4.22.36) OS=Homo sapiens PE=2 SV=1
51 : CASP1_CANFA 0.53 0.81 1 88 2 89 88 0 0 404 Q9MZV7 Caspase-1 OS=Canis familiaris GN=CASP1 PE=2 SV=1
52 : CASP1_HUMAN 0.53 0.80 1 88 2 89 88 0 0 404 P29466 Caspase-1 OS=Homo sapiens GN=CASP1 PE=1 SV=1
53 : F1PBR9_CANFA 0.53 0.81 1 88 2 89 88 0 0 404 F1PBR9 Caspase OS=Canis familiaris GN=CASP4 PE=3 SV=2
54 : F6YZU2_MACMU 0.53 0.78 1 88 2 89 88 0 0 97 F6YZU2 Uncharacterized protein OS=Macaca mulatta GN=CASP1 PE=4 SV=1
55 : F7A0A9_MACMU 0.53 0.78 1 88 2 89 88 0 0 139 F7A0A9 Uncharacterized protein OS=Macaca mulatta GN=CASP1 PE=4 SV=1
56 : F7G5S9_MONDO 0.53 0.76 1 88 2 89 88 0 0 405 F7G5S9 Caspase OS=Monodelphis domestica PE=3 SV=2
57 : F7I1B4_CALJA 0.53 0.76 1 88 1 88 88 0 0 403 F7I1B4 Caspase (Fragment) OS=Callithrix jacchus GN=CASP1 PE=3 SV=1
58 : G3I2E4_CRIGR 0.53 0.74 2 89 1 88 88 0 0 729 G3I2E4 Caspase-12 (Fragment) OS=Cricetulus griseus GN=I79_017574 PE=3 SV=1
59 : G3RYV6_GORGO 0.53 0.80 1 88 2 89 88 0 0 404 G3RYV6 Caspase OS=Gorilla gorilla gorilla GN=101136563 PE=3 SV=1
60 : G3V169_HUMAN 0.53 0.77 16 88 1 73 73 0 0 367 G3V169 Caspase OS=Homo sapiens GN=CASP1 PE=3 SV=1
61 : G7NBS2_MACMU 0.53 0.76 1 88 2 89 88 0 0 404 G7NBS2 Caspase (Fragment) OS=Macaca mulatta GN=EGK_06841 PE=3 SV=1
62 : G7PNL5_MACFA 0.53 0.76 1 88 2 89 88 0 0 342 G7PNL5 Caspase OS=Macaca fascicularis GN=EGM_06174 PE=3 SV=1
63 : G7PNL7_MACFA 0.53 0.76 1 88 1 88 88 0 0 109 G7PNL7 Putative uncharacterized protein (Fragment) OS=Macaca fascicularis GN=EGM_06177 PE=4 SV=1
64 : H2R0S5_PANTR 0.53 0.77 1 88 2 89 88 0 0 404 H2R0S5 Caspase OS=Pan troglodytes GN=CASP1 PE=3 SV=1
65 : H9F298_MACMU 0.53 0.75 17 88 1 72 72 0 0 80 H9F298 Caspase recruitment domain-containing protein 16 isoform 2 (Fragment) OS=Macaca mulatta GN=CARD16 PE=2 SV=1
66 : L9KN40_TUPCH 0.53 0.76 1 88 315 402 88 0 0 1006 L9KN40 Caspase-4 OS=Tupaia chinensis GN=TREES_T100013218 PE=3 SV=1
67 : Q2PFX6_MACFA 0.53 0.75 1 88 2 89 88 0 0 375 Q2PFX6 Caspase OS=Macaca fascicularis PE=2 SV=1
68 : Q5FBZ0_HUMAN 0.53 0.80 1 88 2 89 88 0 0 110 Q5FBZ0 CASP1 nirs variant 1 OS=Homo sapiens GN=CASP1 PE=4 SV=1
69 : CASP1_MOUSE 0.52 0.74 1 89 2 90 89 0 0 402 P29452 Caspase-1 OS=Mus musculus GN=Casp1 PE=1 SV=1
70 : CASP1_RAT 0.52 0.73 1 89 2 90 89 0 0 402 P43527 Caspase-1 OS=Rattus norvegicus GN=Casp1 PE=2 SV=1
71 : F1PDN5_CANFA 0.52 0.81 1 88 2 89 88 0 0 489 F1PDN5 Uncharacterized protein (Fragment) OS=Canis familiaris GN=CASP4 PE=3 SV=2
72 : F7A0D9_MACMU 0.52 0.78 1 88 1 88 88 0 0 109 F7A0D9 Uncharacterized protein (Fragment) OS=Macaca mulatta GN=LOC706971 PE=4 SV=1
73 : H2RDW1_PANTR 0.52 0.75 1 88 2 89 88 0 0 110 H2RDW1 Uncharacterized protein OS=Pan troglodytes PE=4 SV=1
74 : Q91W32_RAT 0.52 0.73 1 89 2 90 89 0 0 402 Q91W32 Caspase OS=Rattus norvegicus GN=Casp1 PE=2 SV=1
75 : F1LQZ4_RAT 0.51 0.73 1 89 1 89 89 0 0 401 F1LQZ4 Caspase (Fragment) OS=Rattus norvegicus GN=Casp1 PE=3 SV=1
76 : G5BVT7_HETGA 0.51 0.75 2 88 1 87 87 0 0 397 G5BVT7 Caspase (Fragment) OS=Heterocephalus glaber GN=GW7_16661 PE=3 SV=1
77 : H2NF48_PONAB 0.50 0.77 1 88 2 89 88 0 0 404 H2NF48 Caspase OS=Pongo abelii GN=CASP1 PE=3 SV=1
78 : K7E6D5_MONDO 0.50 0.71 3 88 8 93 86 0 0 107 K7E6D5 Uncharacterized protein OS=Monodelphis domestica PE=4 SV=1
79 : F7G5F8_MONDO 0.49 0.77 1 88 2 89 88 0 0 403 F7G5F8 Caspase (Fragment) OS=Monodelphis domestica PE=3 SV=1
80 : M3Y4N6_MUSPF 0.49 0.77 1 88 2 89 88 0 0 402 M3Y4N6 Caspase OS=Mustela putorius furo GN=Casp4 PE=3 SV=1
81 : Q8K4I9_MERUN 0.49 0.69 1 89 2 90 89 0 0 402 Q8K4I9 Caspase OS=Meriones unguiculatus PE=2 SV=1
82 : G3TH08_LOXAF 0.48 0.72 1 88 1 88 88 0 0 89 G3TH08 Uncharacterized protein (Fragment) OS=Loxodonta africana PE=4 SV=1
83 : G3W251_SARHA 0.48 0.75 4 88 2 86 85 0 0 489 G3W251 Uncharacterized protein (Fragment) OS=Sarcophilus harrisii GN=LOC100914382 PE=3 SV=1
84 : H0VUL2_CAVPO 0.48 0.72 1 87 2 88 87 0 0 88 H0VUL2 Uncharacterized protein (Fragment) OS=Cavia porcellus PE=4 SV=1
85 : M1EG10_MUSPF 0.48 0.77 2 88 1 87 87 0 0 102 M1EG10 Caspase 4, apoptosis-related cysteine peptidase (Fragment) OS=Mustela putorius furo PE=2 SV=1
86 : G3VHS6_SARHA 0.45 0.70 1 88 2 89 88 0 0 410 G3VHS6 Uncharacterized protein (Fragment) OS=Sarcophilus harrisii GN=LOC100914823 PE=4 SV=1
87 : F6RKH7_ORNAN 0.43 0.71 21 88 2 69 68 0 0 390 F6RKH7 Caspase OS=Ornithorhynchus anatinus GN=LOC100078458 PE=3 SV=2
88 : K7F9M9_PELSI 0.43 0.68 1 88 2 89 88 0 0 348 K7F9M9 Caspase (Fragment) OS=Pelodiscus sinensis PE=3 SV=1
89 : U3KMM0_RABIT 0.43 0.78 1 88 35 122 88 0 0 368 U3KMM0 Caspase OS=Oryctolagus cuniculus PE=3 SV=1
90 : I3J7G7_ORENI 0.42 0.64 1 88 2 89 88 0 0 399 I3J7G7 Caspase OS=Oreochromis niloticus GN=LOC100708386 PE=3 SV=1
91 : I3J7G6_ORENI 0.41 0.63 2 88 3 89 87 0 0 495 I3J7G6 Uncharacterized protein (Fragment) OS=Oreochromis niloticus GN=LOC100708386 PE=3 SV=1
92 : M4AVM2_XIPMA 0.41 0.57 3 88 86 171 86 0 0 468 M4AVM2 Uncharacterized protein OS=Xiphophorus maculatus PE=3 SV=1
93 : M4AVM6_XIPMA 0.41 0.61 1 88 2 89 88 0 0 503 M4AVM6 Uncharacterized protein (Fragment) OS=Xiphophorus maculatus PE=3 SV=1
94 : C1BZD0_ESOLU 0.40 0.66 1 89 2 90 89 0 0 90 C1BZD0 Caspase-1 OS=Esox lucius GN=CASP1 PE=4 SV=1
95 : F6ZRQ4_ORNAN 0.40 0.70 1 88 2 89 88 0 0 97 F6ZRQ4 Uncharacterized protein (Fragment) OS=Ornithorhynchus anatinus PE=4 SV=1
96 : G1MTH2_MELGA 0.40 0.61 1 88 2 89 88 0 0 393 G1MTH2 Caspase (Fragment) OS=Meleagris gallopavo GN=LOC100549639 PE=3 SV=1
97 : U3J1K3_ANAPL 0.40 0.57 1 88 1 88 88 0 0 382 U3J1K3 Caspase (Fragment) OS=Anas platyrhynchos PE=3 SV=1
98 : H6QXT0_DICLA 0.39 0.60 1 87 2 88 87 0 0 90 H6QXT0 Caspase-1 protein OS=Dicentrarchus labrax GN=caspase-1 PE=4 SV=1
99 : I3J6Y0_ORENI 0.39 0.61 1 88 2 89 88 0 0 377 I3J6Y0 Caspase OS=Oreochromis niloticus GN=LOC100702756 PE=3 SV=1
100 : R0LQK1_ANAPL 0.39 0.57 5 88 1 84 84 0 0 377 R0LQK1 Caspase (Fragment) OS=Anas platyrhynchos GN=Anapl_04905 PE=3 SV=1
101 : A8E0J8_SPAAU 0.38 0.62 1 88 2 89 88 0 0 403 A8E0J8 Caspase OS=Sparus aurata GN=casp1 PE=2 SV=1
102 : B5XB12_SALSA 0.38 0.62 1 87 2 88 87 0 0 91 B5XB12 Caspase-1 OS=Salmo salar GN=CASP1 PE=4 SV=1
103 : H2SKU3_TAKRU 0.38 0.65 5 88 6 89 84 0 0 389 H2SKU3 Caspase OS=Takifugu rubripes GN=LOC101080252 PE=3 SV=1
104 : H3DRC4_TETNG 0.38 0.64 5 88 6 89 84 0 0 182 H3DRC4 Uncharacterized protein (Fragment) OS=Tetraodon nigroviridis GN=CARD16 PE=4 SV=1
105 : I3KM76_ORENI 0.38 0.62 1 88 118 204 88 1 1 205 I3KM76 Uncharacterized protein OS=Oreochromis niloticus GN=LOC102081456 PE=4 SV=1
106 : Q4R9W4_TETNG 0.38 0.64 5 88 2 85 84 0 0 105 Q4R9W4 Chromosome undetermined SCAF25114, whole genome shotgun sequence. (Fragment) OS=Tetraodon nigroviridis GN=GSTENG00038706001 PE=4 SV=1
107 : H2T5B5_TAKRU 0.37 0.64 5 88 5 88 84 0 0 404 H2T5B5 Caspase (Fragment) OS=Takifugu rubripes PE=3 SV=1
108 : R7VY69_COLLI 0.37 0.60 5 88 1 84 84 0 0 389 R7VY69 Caspase (Fragment) OS=Columba livia GN=A306_00750 PE=3 SV=1
109 : W0K5I2_MIIMI 0.37 0.58 5 88 5 88 84 0 0 386 W0K5I2 Caspase OS=Miichthys miiuy PE=3 SV=1
110 : G3P6H8_GASAC 0.36 0.64 5 88 6 89 84 0 0 376 G3P6H8 Caspase (Fragment) OS=Gasterosteus aculeatus PE=3 SV=1
111 : H2UDK1_TAKRU 0.36 0.64 2 88 2 88 87 0 0 405 H2UDK1 Caspase OS=Takifugu rubripes PE=3 SV=1
112 : V9L124_CALMI 0.36 0.67 1 89 4 92 89 0 0 385 V9L124 Caspase (Fragment) OS=Callorhynchus milii PE=2 SV=1
113 : W0TYL2_ONCMY 0.36 0.62 1 87 2 88 87 0 0 91 W0TYL2 Iceberg protein OS=Oncorhynchus mykiss GN=iceberg PE=4 SV=1
114 : I3KS50_ORENI 0.35 0.60 1 88 255 340 88 1 2 341 I3KS50 Uncharacterized protein OS=Oreochromis niloticus GN=LOC102082463 PE=4 SV=1
115 : K9K8A7_DICLA 0.35 0.59 1 88 2 89 88 0 0 375 K9K8A7 Caspase OS=Dicentrarchus labrax GN=CASP1 PE=2 SV=1
116 : K9K902_DICLA 0.35 0.59 1 88 2 89 88 0 0 289 K9K902 Caspase 1 isoform 4 OS=Dicentrarchus labrax GN=CASP1 PE=2 SV=1
117 : K9K974_DICLA 0.35 0.59 1 88 2 89 88 0 0 328 K9K974 Caspase OS=Dicentrarchus labrax GN=CASP1 PE=2 SV=1
118 : Q07BT4_DICLA 0.35 0.59 1 88 2 89 88 0 0 394 Q07BT4 Caspase OS=Dicentrarchus labrax GN=CASP1 PE=2 SV=1
119 : A1E8J0_FRG3V 0.34 0.57 1 88 5 92 88 0 0 95 A1E8J0 Caspase recruitment domain only protein OS=Rana grylio virus 9506 PE=4 SV=1
120 : A2BGE2_DANRE 0.34 0.61 1 89 2 90 89 0 0 366 A2BGE2 Caspase OS=Danio rerio GN=si:dkey-103e21.5 PE=3 SV=1
121 : B1PXL2_9VIRU 0.34 0.56 1 88 5 92 88 0 0 95 B1PXL2 Caspase recruitment domain protein OS=Ambystoma tigrinum virus PE=4 SV=1
122 : B1PXN2_9VIRU 0.34 0.55 1 88 5 92 88 0 0 95 B1PXN2 Caspase recruitment domain protein OS=Ambystoma tigrinum virus PE=4 SV=1
123 : B1PXN4_9VIRU 0.34 0.53 1 88 5 92 88 0 0 95 B1PXN4 Caspase recruitment domain protein OS=Ambystoma tigrinum virus PE=4 SV=1
124 : B1PXP2_9VIRU 0.34 0.55 1 88 5 92 88 0 0 95 B1PXP2 Caspase recruitment domain protein OS=Ambystoma tigrinum virus PE=4 SV=1
125 : B5X8J4_SALSA 0.34 0.57 1 89 140 227 89 1 1 233 B5X8J4 Caspase-1 OS=Salmo salar GN=CASP1 PE=2 SV=1
126 : C3RWR6_FRG3V 0.34 0.57 1 88 5 92 88 0 0 95 C3RWR6 CARD-like caspase OS=Soft-shelled turtle iridovirus GN=ORF067R PE=4 SV=1
127 : D3TTS4_9VIRU 0.34 0.56 1 88 5 92 88 0 0 95 D3TTS4 CARD-like caspase OS=Epizootic haematopoietic necrosis virus PE=4 SV=1
128 : F6ZH96_XENTR 0.34 0.64 5 89 6 90 85 0 0 402 F6ZH96 Caspase (Fragment) OS=Xenopus tropicalis GN=casp1 PE=3 SV=1
129 : H6WEI7_FRG3V 0.34 0.59 1 88 5 92 88 0 0 95 H6WEI7 CARD-like caspase OS=Common midwife toad ranavirus PE=4 SV=1
130 : H9XFN1_FRG3V 0.34 0.57 1 88 5 92 88 0 0 95 H9XFN1 Interleukin-1 beta convertase card caspase recruitment domain cop protein OS=Rana grylio iridovirus GN=ORF68R PE=4 SV=1
131 : M4ACI5_XIPMA 0.34 0.59 1 88 220 306 88 1 1 309 M4ACI5 Uncharacterized protein (Fragment) OS=Xiphophorus maculatus PE=4 SV=1
132 : M4AUY8_XIPMA 0.34 0.60 4 88 5 89 85 0 0 391 M4AUY8 Caspase (Fragment) OS=Xiphophorus maculatus PE=3 SV=1
133 : M4AVM7_XIPMA 0.34 0.59 1 86 2 87 86 0 0 383 M4AVM7 Caspase OS=Xiphophorus maculatus PE=3 SV=1
134 : 064R_FRG3G 0.33 0.55 1 88 5 92 88 0 0 95 Q6GZR1 Caspase recruitment domain-containing protein 064R OS=Frog virus 3 (isolate Goorha) GN=FV3-064R PE=4 SV=1
135 : B1PXL4_9VIRU 0.33 0.56 1 88 5 92 88 0 0 95 B1PXL4 Caspase recruitment domain protein OS=Ambystoma tigrinum virus PE=4 SV=1
136 : B1PXM0_9VIRU 0.33 0.56 1 88 5 92 88 0 0 95 B1PXM0 Caspase recruitment domain protein OS=Ambystoma tigrinum virus PE=4 SV=1
137 : H3B2V3_LATCH 0.33 0.64 1 89 2 90 89 0 0 394 H3B2V3 Caspase OS=Latimeria chalumnae PE=3 SV=1
138 : Q6YH84_9VIRU 0.33 0.56 1 88 5 92 88 0 0 95 Q6YH84 CARD-like caspase OS=Ambystoma tigrinum stebbensi virus PE=4 SV=1
139 : T2C5H7_FRG3V 0.33 0.55 1 88 5 92 88 0 0 95 T2C5H7 CARD-like caspase OS=Andrias davidianus ranavirus GN=ORF43L PE=4 SV=1
140 : V5N0P0_FRG3V 0.33 0.55 1 88 5 92 88 0 0 95 V5N0P0 CARD-like caspase OS=Chinese giant salamander iridovirus PE=4 SV=1
141 : B1PXM2_9VIRU 0.32 0.56 1 88 5 92 88 0 0 95 B1PXM2 Caspase recruitment domain protein OS=Ambystoma tigrinum virus PE=4 SV=1
142 : CAS1A_XENLA 0.32 0.60 5 89 5 89 85 0 0 386 P55865 Caspase-1-A OS=Xenopus laevis GN=casp1-a PE=2 SV=1
143 : I3KI24_ORENI 0.32 0.60 1 88 264 350 88 1 1 350 I3KI24 Uncharacterized protein (Fragment) OS=Oreochromis niloticus GN=LOC102082608 PE=4 SV=1
144 : M4A0C6_XIPMA 0.32 0.51 1 88 446 531 88 1 2 532 M4A0C6 Uncharacterized protein OS=Xiphophorus maculatus PE=4 SV=1
145 : Q2WER7_RTRV 0.32 0.57 5 88 1 84 84 0 0 87 Q2WER7 CARD-like caspase OS=Rana tigrina ranavirus PE=4 SV=1
146 : Q5GAJ3_9VIRU 0.32 0.59 5 89 7 91 85 0 0 91 Q5GAJ3 CARD-like caspase OS=Grouper iridovirus GN=GIV23 PE=4 SV=1
147 : Q5YFL7_9VIRU 0.32 0.59 5 89 7 91 85 0 0 91 Q5YFL7 CARD-like protein OS=Singapore grouper iridovirus GN=ORF048L PE=4 SV=1
148 : W5L5A0_ASTMX 0.32 0.60 1 88 2 89 88 0 0 381 W5L5A0 Uncharacterized protein OS=Astyanax mexicanus PE=4 SV=1
149 : B5XEY3_SALSA 0.31 0.55 1 89 140 227 89 1 1 233 B5XEY3 Caspase-1 OS=Salmo salar GN=CASP1 PE=2 SV=1
150 : B7ZQX3_XENLA 0.31 0.58 5 89 5 89 85 0 0 382 B7ZQX3 Caspase OS=Xenopus laevis GN=casp1-A PE=2 SV=1
151 : CAS1B_XENLA 0.31 0.58 5 89 5 89 85 0 0 382 P55867 Caspase-1-B OS=Xenopus laevis GN=casp1-b PE=2 SV=1
152 : H3B2V4_LATCH 0.31 0.64 1 89 2 90 89 0 0 394 H3B2V4 Caspase (Fragment) OS=Latimeria chalumnae PE=3 SV=1
153 : I3J8H0_ORENI 0.31 0.56 1 88 246 332 88 1 1 332 I3J8H0 Uncharacterized protein (Fragment) OS=Oreochromis niloticus GN=LOC102078647 PE=4 SV=1
154 : Q678K6_9VIRU 0.31 0.61 3 89 6 91 87 1 1 100 Q678K6 Putative uncharacterized protein OS=Lymphocystis disease virus - isolate China PE=4 SV=1
155 : U6IEP8_HYMMI 0.30 0.57 1 86 2 87 86 0 0 2107 U6IEP8 Uncharacterized protein OS=Hymenolepis microstoma GN=HmN_000209300 PE=4 SV=1
156 : W5LZT4_LEPOC 0.30 0.61 1 89 2 90 89 0 0 377 W5LZT4 Uncharacterized protein OS=Lepisosteus oculatus PE=4 SV=1
157 : W5LZV0_LEPOC 0.30 0.61 1 89 2 90 89 0 0 387 W5LZV0 Uncharacterized protein (Fragment) OS=Lepisosteus oculatus PE=4 SV=1
## ALIGNMENTS 1 - 70
SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
1 2 A A 0 0 148 117 46 A T A TAAATTT AAAATPPPAAATT T AAATA AAA AAAAAAAAAAAA A TATA PAAAA
2 3 A D + 0 0 90 130 35 DDDDDDD D GDDDDDDDDDDDDDDDDDDDDDDDDDDDD DDD DDDDDDDDDDDDDD DDDD HDDDD
3 4 A Q > + 0 0 102 133 49 QQQQQQK K NKQKKKKKKKKKKRKKKKKKKKKKKKKKK KKM KKKKKKKKKKKKNK KKKK KKKKK
4 5 A L H > S+ 0 0 56 136 81 LLVLLLV L VVTVVIIVVDVIVIDDVVVIIIIIVVIVV VVIVVVVVVVVVVVVVIV VVVF VVVIV
5 6 A L H 4 S+ 0 0 5 151 7 LLLLLLL L LLLLLLLLLLLLLLLLLLLLLLLLLLLLL LLLLLLLLLLLLLLLLLL LLLL LLLLL
6 7 A R H >4 S+ 0 0 116 151 74 RRRHHFK K KKRKRKKKKKKKKKKKKKKKKKKKKKKKK KKLKKKKKKKKKKKMKRK KKKK RKKRR
7 8 A K H >< S+ 0 0 151 152 66 KKKKKKE EEEEDEEEEEEGGEEDGGEEEEEEEEEEEEE EEKQEEDEEDEDEEEEAE EEEE EEEAA
8 9 A K T 3X S+ 0 0 66 152 79 KKKKKKK KKKKKKKKKKKKKKKRKKKKKKKKKKKKKKK KKKKKKKKKKKKKKKKKK KKKK KKKKK
9 10 A R H <> S+ 0 0 106 152 1 RRRRRRR RRRRRRRRRRRRRRRRRRRRRRRRRRRRRRR RRRRRRRRRRRRRRRRRR RRRR RRRRR
10 11 A R H <> S+ 0 0 173 152 83 RRRIIRR KKRKKMRRRMRKKKVKKKKKRKKKRKKKRKK KKWKKKRKKRKRKKRKKK KKKK KKKKK
11 12 A I H 4 S+ 0 0 43 153 88 IIIIIILVLLLLLVQLLVLQQFVRQQLLLFFFLFLLLLQ LQLLLLLLLLLLLLLLQL LLLL LLLQQ
12 13 A F H >X S+ 0 0 0 153 5 FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF FFLFFFFFFFFFFFFFFF FFFF FFFFF
13 14 A I H 3< S+ 0 0 19 153 21 IIIIIIIVVVIVVVIIIVVIIIVIIIVIVIIIIIIIVVI IIIIIIVIIVIVIIVIII IIII IIIII
14 15 A H T 3< S+ 0 0 118 153 72 HHHHHHRQHHRHSQQQQQRNNRQNNNHHRRRRRRRHRHR HCNRRRRRRRRRHHECRR HHHR NHRNN
15 16 A S T <4 S+ 0 0 72 153 73 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS SSSSSSSSSSSSSSSSSS SSSS SSSSS
16 17 A V < - 0 0 5 156 52 VVVVVVVVVVVVVVVVVVVVVVVVVVVMVVVVVVMMVVVMMMALVMMVMMVMVMMVVVMMTTMM VTMVV
17 18 A G > - 0 0 34 157 63 GGGGGGGTSSGSNTGEETGGGGTGGGSGAGGGGGGGASGGGGGGNGGDGGDGDGGDDGGGGGGGGSGGSS
18 19 A A H > S+ 0 0 61 157 84 AAAAAATEKKTKTSTAASAMMESTMMTEMEEEEEEEMTEEEEEETEEMEEMEMEEREAEEEEEEETEEIV
19 20 A G H >> S+ 0 0 52 157 56 GGGGGGGGGGGGGGGGGGGGGGGGGGDGGGGGGGGGGDGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
20 21 A T H 3> S+ 0 0 21 157 54 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTVATTTTTTTTTTTTT
21 22 A I H 3X S+ 0 0 2 158 23 IIIIIIVIIIVILIIIIIMVVIIIVVIIIIIIIIIIIIIIIIIIIIIIIIIIIIIMIIIIIIIIIIIIII
22 23 A N H X>S+ 0 0 2 157 13 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
29 30 A L H ><5S+ 0 0 66 157 20 LLLLLLLLLLLLLLLLLLLFFLLLFFLLLLLLLLLLLLLLLLFLLLLFLLFLFLLLLLLLLLLLLLLLLL
30 31 A E H 3<5S+ 0 0 139 158 55 EEEEEEEEEEEEEEEEEEEEEEEEEEQQEEEEEEQQEQEQEQEEEQQEQQEQEQQEEEQQQQQQQEQQEE
31 32 A D H <<5S- 0 0 50 158 71 DDDDDDKKKKKKKKKKKKKKKKKKKKKTTKKKKKTTTKTTTTTTKTTKTTKTKTTVKKTTTTTTTKTTKK
32 33 A E T <<5 + 0 0 158 158 68 EEEEERRRRRRRRRRRRRKNNRRRNNRRRRRRGRRRRRRRRRRNRRRRRRRRRRRQSNRRRRRRRKRRRR
33 34 A V < + 0 0 46 158 11 VVVIIVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVV
34 35 A I S S- 0 0 25 157 23 IIIIIILLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
35 36 A S >> - 0 0 55 158 32 SSSSSSNNNNNNNNNNNNSNNNNNNNNNNNNNNNNNNNSNNNSSNNNNNNNNNNNNNNNNNNNNNNNNNN
36 37 A Q H 3> S+ 0 0 137 158 51 QQQQQQQQQQQQQQQQQQQQQEQQQQQQQEEEEEQQQQQQQQQQQKKHKKHKHQQLQQKKQQQQQLLKQQ
37 38 A E H 3> S+ 0 0 157 158 52 EEEEEEEEEEEEEEEEEEEEEEEEEEGEEEEEEEEEEGEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE
38 39 A D H X> S+ 0 0 25 158 20 DDDDDDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE
39 40 A M H 3X S+ 0 0 37 158 69 MMMMMMMMMMMTMMMMMMMMMMMMMMMMVMMMIMMMVMIMMMITMMMMMMMMMMMMMMMMMMMMMMMMMM
40 41 A N H 3X S+ 0 0 79 157 39 NNNNNNEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEVEEDD
41 42 A K H << S+ 0 0 89 158 78 KKKKKKKKKKKKRKKKKKKRRKKKRRKKIKKKKKKKIKIKKKIIKKKRKKRKRKKIKRKKKKKKKRKKKT
42 43 A V H >< S+ 0 0 14 158 25 VVVVVVVVVIVVVVVVVVVVVVVVVVIVVVVVVVVVVIVVVVVVVVVVVVVVVIIVVIVVVIVVIIVVII
43 44 A R H 3< S+ 0 0 169 158 80 RRRRRRRRRRRRRRRRRRRKKKRRKKRKRKKKKKKKRRKKKKKKRKKRKKRKRKKRKKKKKKKKKRKKKK
44 45 A D T 3< S- 0 0 116 158 78 DDDDDDDRDDDDYRDAANDCCRRVCCDRGRRRRRRCGDCRCRCCHRRCRRCRCRRERCRRRRCRRDRRLL
45 46 A E < - 0 0 109 158 59 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAEEAEAEEEEIEEEEEEEGEEAA
46 47 A N - 0 0 84 155 32 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNHNNHNHNNSNNNNNNNNNNNNNN
47 48 A D S S+ 0 0 115 157 76 DDDDDDADDDADAAAAAAPAAADAAAIAAAAAAAAAAIAAAAAIAAASAASASPPKAAAAPPAAPAPAII
48 49 A T S >> S- 0 0 80 158 52 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTPATTTTTTTTTTTTTTTTTTTTMTTTTTTT
49 50 A V H 3> S+ 0 0 35 156 82 VVVVVVVDAAVAVDVVVDVVVVIVVVTVVVVVVVVVVTVVVVVVVVVVVVVVVVVNVVVVVVVAVVVVAV
50 51 A M H 3> S+ 0 0 102 158 75 MMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMRMMMMMMMMMMMMMM
51 52 A D H <> S+ 0 0 45 158 9 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDE
52 53 A K H X S+ 0 0 38 158 47 KKKKKKKKRRKRKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKQKKQKQKKKKKKKKKKKKKKKKK
53 54 A A H X S+ 0 0 0 158 22 AAAAAAAAAAAAAAAAAAAAAAAAAAATAAAAAATTAAATATAAATTATTATATTAAATTAAATTAATAA
54 55 A R H X S+ 0 0 106 157 8 RRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRQRRRRRRRRRRRRRRRRRRRRRRRRRRR
55 56 A V H X S+ 0 0 3 158 70 VVVVVVAAVVAVAAAAAAAAAAAAAAVAAAAAAAAAAVAAAAAAAAAVAAVAVAAVADAAAAAAAAAADD
56 57 A L H X S+ 0 0 4 158 9 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLVVLLLLLVVLLVLVLLL
57 58 A I H X S+ 0 0 4 158 22 IIIIIIIIIIIIIIITTIMIILILIIIIILLLLLIIIILILILLIIIIIIIIIIIIFCIIIILIIIIICC
58 59 A D H X S+ 0 0 104 158 2 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
59 60 A L H X S+ 0 0 23 158 65 LLLLLLASITAYSSGSSSASSSSCSSISSSSSSSSSSISSSSSASSSSSSSSSSSASSSSSSSSSTSSHH
60 61 A V H >< S+ 0 0 0 158 5 VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVV
61 62 A T H >< S+ 0 0 39 158 81 TTTIIIITIIIILTIIITILLIIILLIIIIIIIITIIIIIIIIFIIILIILILIIIITIIIIIIIIIIST
62 63 A G H 3< S+ 0 0 56 158 60 GGGGGGRRRRRRRRRKKRRRRRPRRRCPRRRRRRPPRCRPRPRRRPPRPPRPRRRSWKPPRRRPRPRPKK
63 64 A K T << S- 0 0 82 158 4 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
64 65 A G X> - 0 0 25 158 1 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
65 66 A P H 3> S+ 0 0 67 157 68 PPPPPPPDPPPPSDPPPAPPPADPPPPAPAAAAAAAPPAAAA.APAAPAAPAPAAPAPAAAAAAAPAAPP
66 67 A K H 3> S+ 0 0 155 158 83 KKKKKEQKRQQWQKQMMKRRRQKQRRRQQQQQRQQQQRPQPQARQQQNQQNQNQQKPLQQQQPQQKQQQR
67 68 A S H <> S+ 0 0 4 158 15 SSSSSAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAPAAAAAAAAAAAAAAAAAAAAAAAAAAA
68 69 A C H X S+ 0 0 28 158 32 CSCCCCCSCCCCCSSCCSCCCCSCCCCCCCCCCCCCCCCCCCACSCCCCCCCCSSSCSCCSSCCSSSCSS
69 70 A C H X S+ 0 0 52 158 73 CCCLLRQKQQQQQKQQQKQQQHQQQQQQQHHHQHQQQQQQHQCEQQQQQQQQQQQQQQQQQQHQQQQQQQ
70 71 A K H X S+ 0 0 81 158 68 KKKKKKIVIIIIIVVIIVVIIIVIIIIIIIIIVIIIIIIIIIKIIIIIIIIIIIICVIIIIIIIIIIIIM
71 72 A F H X S+ 0 0 0 158 60 FFFFFFFCCCFCFCFFFCCFFFCCFFCCCFFFCFCCCCCCCCFCCCCFCCFCFFFFCCCCCCCCFCCCFF
72 73 A I H X S+ 0 0 29 158 36 IIIIIIIIIIIIIIIIIIVIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIITIIIIIIIIIIIIII
73 74 A K H X S+ 0 0 120 158 77 KKKKKRGDSSGSCDITTDNCCTDNCCSTNTTTTTTTNSTTTTTTGTTSTTSTSTTKTTTTTTTTTNTTTT
74 75 A H H X S+ 0 0 23 158 86 HRHHHHHHHHHHYHNHHHHHHYHHHHHYHYYYYYYYHHYYYDYYYYYNYYNYNYYSNYYYYYYYYSYYYY
75 76 A L H X S+ 0 0 1 158 21 LLLLLLIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
76 77 A C H < S+ 0 0 45 158 83 CCCCCCCCCCCCCCCCCCCCCCRCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCGCCCC
77 78 A E H < S+ 0 0 143 158 68 EEEEEEEEEEEEDENKKEEEEEKEEEEEGEEEEEEEGEEEEEEEEEENEENENEEEEKEEEEEEEEEENN
78 79 A E H < S+ 0 0 78 158 72 EEEEEEDIEEDEEINDDIDEEEIDEEEEDEEEEEEEDEEEEEEEDEEEEEEEEEEREEEEEEEEEDEEEE
79 80 A D X + 0 0 32 158 7 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
80 81 A P T 4 S+ 0 0 106 158 85 PPPPPPPSSSPSSSCCCSATTHSCTTSSPHHHRHKSPSSSSSSRCSSISSISIRRGCCSSRRRNRCRSCC
81 82 A Q T >4 S+ 0 0 125 158 89 QQQQQPHHHHHHFHHYYHHHHHQHHHHYHHHHHHYYHHHYHYHYHYYHYYHYHYYHHYYYYYYYYHYYYY
82 83 A L G >4 S+ 0 0 4 158 5 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
83 84 A A G >< S+ 0 0 6 158 51 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAVAAAAAAAAAAAAA
84 85 A S G X S+ 0 0 82 158 63 SSSAASEEGGEGEEQGGEDEEGEGEEGEGGGGEGQRGGGEGQGGEGGQGGQGQGGEDGGGGGGGGEGGGE
85 86 A K G < S+ 0 0 120 158 81 KKKKKKTKIITIKKTTTKVTTTKLTTITVTTTKTTTVITTTTTTVTTTTTTTTTTKRVTTTTTTTKTTII
86 87 A M G < S+ 0 0 0 158 8 MMMMMMLMLLLLMMLLLMLLLLMLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLQLLLLLLLLLLLLL
87 88 A G < + 0 0 30 156 30 GGGGGGRGGGRGGGQGGGQGGGGGGGGGEGGGGGGGEGGGGGGGEGGGGGGGGGGGGEGGGGGGGQGGEE
88 89 A L 0 0 108 152 13 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL
89 90 A H 0 0 234 28 55 H HHHR E QQ
## ALIGNMENTS 71 - 140
SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....8....:....9....:....0....:....1....:....2....:....3....:....4
1 2 A A 0 0 148 117 46 PTAAT A TAAT T T ASA PAPPAAA AA A AAPAAAAGAGGGGPGG GGP AGGGAGGG
2 3 A D + 0 0 90 130 35 DDDDDDD DDDD DDD DDDD DDADADD AA D EDADDDDDADAAAAEAA AAK DAAAGAAA
3 4 A Q > + 0 0 102 133 49 KKKKKVKQKKAK MKI RKKKKKQQQQQK KQ E DQQKKKKKQQQQQQQQQ QQE KQQQEQQQ
4 5 A L H > S+ 0 0 56 136 81 VVVVIIVQVITVVTII QREEEEKLEEEE EQ R KMQHEEEEELEEEEQEE EEQVEEKKRKEE
5 6 A L H 4 S+ 0 0 5 151 7 LLLLLLLLLLLLLMLL LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLMLIIIILMMLMMLLLMIILIMM
6 7 A R H >4 S+ 0 0 116 151 74 KKKRRQKKKKRLKKKK GKGGDESKLLAALTRDAFAALHKTKHFFFFFRERRRRRRRKRRIQSRRRKRRR
7 8 A K H >< S+ 0 0 151 152 66 DEEAAGEEEDSEEEDE SERRRGQDRKQRKRESRTRSNSKSRGARRRRKNKKKKSKKKKKEKKKKKKKKK
8 9 A K T 3X S+ 0 0 66 152 79 KKKKKKKKKRKKKKRK VKVVVVVRAVVVVVLIVIVIVVVILLVVVVVGLGGGGVGGVGGIVVGGGLGGG
9 10 A R H <> S+ 0 0 106 152 1 RRRRRRRKRRRRRRRR RRRRRRRWRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRKRRRRRRRR
10 11 A R H <> S+ 0 0 173 152 83 RKKKKKKNRRTKKKRK TKAASDNCAASGASTLPSPPTSTLGTKSSSSLPLLLLTLLKLLIYGLLLRLLL
11 12 A I H 4 S+ 0 0 43 153 88 LLQQQQLMLLKLLQLR RLDDREELDDARDDKMKRKMEKKMDKQKKKKVDAAAAEVALVVNRKAAAEAAA
12 13 A F H >X S+ 0 0 0 153 5 FLFFFFFFFFFFFFFF FFFFFFFIFFFFFFFFFFFFFFFFLFFFFFFFLFFFFFFFFFFFFFFFFFFFF
13 14 A I H 3< S+ 0 0 19 153 21 VIIIIVIVVVIIVVVV VVVVVVVIVVVVVVIVVIVVVVVVIIVVVVVVIVAAAVVVIVVIVVVVVAVVV
14 15 A H T 3< S+ 0 0 118 153 72 RRCNNRREESNQERSE EDTTGQAEGEDEEGEEEDEEEDEEKEDEEEERKRRRRIRRDRRDYERRRDRRR
15 16 A S T <4 S+ 0 0 72 153 73 SSSSSSSSSSSASSSS SSSSKRRSRRRKRSKKKSKKRKKKGKQKKKKLGLLLLRLLGLLGKKLLLNLMM
16 17 A V < - 0 0 5 156 52 VMAVVVMVVVVVVVVA VVVVVVVLVVVVVVVVVVVVVVAVLVVVVVVSLSSSSVSSCSSIVVSSSVSSS
17 18 A G > - 0 0 34 157 63 DGGSSGGNDSDNDGSN SSSSSSSTRRSSRSSSSSSSSTSSSSSSSSSKSKKKKSKKNKKSSSKKKSKKK
18 19 A A H > S+ 0 0 61 157 84 MEEVVTEKRPGEKTPK KEKKKDKHKKKKKKKTTETTKKMTKKDKKKKLELLLLGLLALLGRKLLLKLRR
19 20 A G H >> S+ 0 0 52 157 56 GGGGGGGDGGGGGGGG ADAAEAPGAPVAPATQQSQQPPSQGASDDDDEREEEEPEEAEEPHPEEEPEEE
20 21 A T H 3> S+ 0 0 21 157 54 TTTTTTTIVTITLTTV VTVVVVVMVLLLLVIMMIMMLVLMVVTLLLLTVTTTTVTTITTVVITTTVTTT
21 22 A I H 3X S+ 0 0 2 158 23 IIIIIIIIILIIIILIIILIIIIIIIIILIILIILIIIIIIILVIIIILILLLLLLLILLLLLLLLLLLL
22 23 A N H X>S+ 0 0 2 157 13 LLLLLLLLLLLLLLLLLLVLLLCLLLLLLLMLIILIILILIMLLIIIIMLMMMMLMMLMMLLLMMMLMMM
29 30 A L H ><5S+ 0 0 66 157 20 FLFLLLLLLLLLLLLLLLLVVLLLLLLLLLLLFLLLFLLLFLLLLLLLLQLLLLLLLLLLLLLLLLLLLL
30 31 A E H 3<5S+ 0 0 139 158 55 EEEEEEQEEDEEEEDEQEHEEHKEQAAQEAEEMLQLMAEDMDEQAAAAAQAAAAQAADAAKKEAAAEAAA
31 32 A D H <<5S- 0 0 50 158 71 KTTKKKTSLQKRVKQIMKEDDDDDMHHDEHDDDDQDDQDNDHDQDDDDEKEEEEHEEKEEEDDEEEQEEE
32 33 A E T <<5 + 0 0 158 158 68 RRRRRRRGQKRKKRKKQQKGGGHKQKKGGKAMGGRGGGGGGEMGCCCCRKRKKRTRRSRRKHRRRRKRRR
33 34 A V < + 0 0 46 158 11 VVVVVVVMVVVVVVVVVVVVVVVVVVVILVIVIIVIIVIIIVVIIIIIVVVVVVVVVVVVIVLVVVVVVV
34 35 A I S S- 0 0 25 157 23 LLLLLLLILLLLLLLLILLLLLFLILLLLLLLVVIVVLILVILIVVVVFFFFFFIFFLFFILLFFFLFFF
35 36 A S >> - 0 0 55 158 32 NNSNNNNTNNNSNNNNNNNNNNNNNNSNNSNNSSNSSNNNSNNNNNNNNGNNNNNNNTNNNNNNNNNNNN
36 37 A Q H 3> S+ 0 0 137 158 51 HQQQQKKQLQERQQQQQEQDDEYEQQQDDQDDEEDEELDDENDKDDDDEEEEEEQEEDEEDGDKEEEEEE
37 38 A E H 3> S+ 0 0 157 158 52 EEEEEEEEEEEEEEEEEEEMMGEEEAGGGGGGMMQMMQGGMSGEGGGGGEGGGGEGGSGGSEGGGGGGGG
38 39 A D H X> S+ 0 0 25 158 20 EEEEEEEKEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEQEEEEEEEEHEQHQQEHQEQHEEEEQQEQLL
39 40 A M H 3X S+ 0 0 37 158 69 MMIMMVTMMMMMMVMMMVISSKKKMVVKIVKMKKMKKVKKKKIMRRRRAIAAAAMAAVAAMEVAAAYAAA
40 41 A N H 3X S+ 0 0 79 157 39 EEEDDEEEEEEQEQEEDEEEEDDDDDDDDDEEEE.EEDEDEEEDDDDDAEAAAAEAAEAAEDEAAAEAAA
41 42 A K H << S+ 0 0 89 158 78 RKITTIKEIRRIIIRITEKSSAASTEESSESESSESSESSSDESSSSSDDDDDDSDDYDDAISDDDADDD
42 43 A V H >< S+ 0 0 14 158 25 VVVIIVVLLVIIVIVVVVVIIVIVVVVIVVIIIISIIVIIIIIAIIIIIIIIIIVIIIIIVIVIIILIII
43 44 A R H 3< S+ 0 0 169 158 80 RKKKKRKRKRKIRTRRRRKLLVLKRQQLLQLKTTFTTQALTLKRIIIILQLLLLKLLNLLECLLLLKLLL
44 45 A D T 3< S- 0 0 116 158 78 CCCLLSRDECAHECCEEEKEEEEEEEEEKEEDEEREEDEEEEEIEEEEEHEEEEVEEEEEAEEEEEEEEE
45 46 A E < - 0 0 109 158 59 AEEAAGEEEEEQEGEEEGGEEEEEEAGEDGENEESEEREEEANKEEEESRSSSSISSCSSEGDSSSGSSS
46 47 A N - 0 0 84 155 32 HNNNNNNNSNNNNNNNHHNNNNNNHNYNNYNNSNKNSYINSNN.NNNNNMNNNNANNNNNRRNNNNSNNN
47 48 A D S S+ 0 0 115 157 76 SAAIIVAVRAAPKSAKHSIDDDRNHPAVSAPMNNQNNVPGNSM.VVVVDKDDDDEDDADDTYTDDDTDDD
48 49 A T S >> S- 0 0 80 158 52 TPTTTITTTTTTTTTTRKASSSTARVVSNVAPIVSVIVSTIRLPNNNNTTTTTTRTTITTRSNITTRTTT
49 50 A V H 3> S+ 0 0 35 156 82 VVVVVLVMITVDIVTIPKVRRRRRPTTRKTRRRRRRRRRKRTRRRRRRRRRRRRTRRTRR.RKRRRRRRR
50 51 A M H 3> S+ 0 0 102 158 75 MMMMMMMMRTKMRMTNASTAAAAAATGAAGAASSASSTAASGAAAAAAAAAAAAEAAKAARAAAAAGAAA
51 52 A D H <> S+ 0 0 45 158 9 DDDEEDDDDDDKDDDYEDGDDDNEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDKDDDDDDDDDDDDDDD
52 53 A K H X S+ 0 0 38 158 47 QKKKKKKKKKKKQKKQKQKKKKKQKKKKMKQKKKKKKKQRKQKRRRRRIQIIIIAIIRIIKQMIIIKIII
53 54 A A H X S+ 0 0 0 158 22 AAAAAATAAAAAAAAATAAAAAAATAAAAAAAAAAAAAAAAAAAAAAAAAAAAARAACAAAAAAAAAAAA
54 55 A R H X S+ 0 0 106 157 8 RRQRRRRLRRRRRRRLRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRR.RRRRRRRRRRRLRRR
55 56 A V H X S+ 0 0 3 158 70 VAADDAAAVAHARAARACDCCCACASCSACDQRRDRRCANRSQDDDDDAHAAAADAARAAVSCAAAEAAA
56 57 A L H X S+ 0 0 4 158 9 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLMLLLLLLLLVLLLLLVLLLLILLMLLLLLLLLLLMM
57 58 A I H X S+ 0 0 4 158 22 ILLCCVLIIICIIVIILIIIIIIILIIIIIIIIIIIIIIIILIILLLLIIIIIIIIIIIIIIIIIIIIII
58 59 A D H X S+ 0 0 104 158 2 DDDDDDDEDDDDDDDDNDDDDDDDNDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
59 60 A L H X S+ 0 0 23 158 65 SSSHHASYASSSISSNSGSIIKLMSTATMATSLSTSSCTVSTSVTTTTSDSSSSMSSNSSTYISSSISSS
60 61 A V H >< S+ 0 0 0 158 5 VVVVVLLVIIVVVLIVVVVVVVVVVVVVVVVVVVVVVVVVVIVVVVVVVVVVVVVVVIVVVVVVVVVVVV
61 62 A T H >< S+ 0 0 39 158 81 LIITTIIIIITVIIISIRIKKKIRIRRKKRKRRKRKRRKKRKRRKKKKTKTTTTLTTKTTRIRTTTRTTT
62 63 A G H 3< S+ 0 0 56 158 60 RRRKKGPWSRQPRGRNPKPKKRKKPLLRRLKRKKRKKLKAKRRNRRRRKRKKKKRKKNKKRRKKKKKKKK
63 64 A K T << S- 0 0 82 158 4 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKQQKQKK
64 65 A G X> - 0 0 25 158 1 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
65 66 A P H 3> S+ 0 0 67 157 68 PAAPPPAPPPPHSPPSDASDDHAPDPSDDSDNEESEESDNEANEDDDDDVDDDDTDDDDDDETDDDQDDD
66 67 A K H 3> S+ 0 0 155 158 83 NPPRRQREKQERKQQKLRRTTEEQLRKVKKDTRRERRRNKRRTEVVVVVKVVVVEVVYVVDRRVVVKVVV
67 68 A S H <> S+ 0 0 4 158 15 AAAAAAAAAAAAAAAAAAAAAATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAASAAAAGAAAAAAA
68 69 A C H X S+ 0 0 28 158 32 CCCSSCCCSCSCSCCSSSCSSSCSSSSSSSSSCSSSCSSSCSSSSSSSCSCCCCSCCSCCSSSCCCSCCC
69 70 A C H X S+ 0 0 52 158 73 QHQQQQEQQQQQQQQQQEQSSSEKQAQRRQREKRSRKQWEKQESRRRRSESSSSSSSNSSSTKSSSESSS
70 71 A K H X S+ 0 0 81 158 68 IIIMMIILCIIIYIIHIIVKKKKKIIIKKIKRKKLKKIKIKKKSKKKKLILLLLRLLILLERMLLLKLLL
71 72 A F H X S+ 0 0 0 158 60 FCCFFCCLFLLCLCLLFFFMMMMMFFFMMFFFMLLLMFFLMFFLFFFFFMFFFFMFFLFFMLLFFFFFFF
72 73 A I H X S+ 0 0 29 158 36 IIIIIIIITIIIIIIIIIIIIIIIIIILIIILIIIIIIIIIILIIIIIALAAAAIAALAAIIIAAAIAAA
73 74 A K H X S+ 0 0 120 158 77 STTTTSTKKATSKDAKDRDVVAGGDDDAEDEISEAESDAASEIDAAAAGAGGGGNGGQGGHYDGGGQGGG
74 75 A H H X S+ 0 0 23 158 86 NYYYYYYSSFYYSYFSSCHHHHYRSSSHHSRRHHAHHSHSHARGHHHHASAAAALAACAAFHHAAASAAA
75 76 A L H X S+ 0 0 1 158 21 IIIIIIIIIIIIIIIILLILLLLVLLLLLLILIIIIILILILLLIIIIILIIIILIILIILLIIIIIIII
76 77 A C H < S+ 0 0 45 158 83 CCCCCCCWWCCCIYCICCCKKEEQCRRQERKQQQCQQRKEQKQRQQQQAKAAAAGAAVAACQKAAAQAAA
77 78 A E H < S+ 0 0 143 158 68 NEENNEEHEAKDEEAEKCQSSSREKKKIKKNESSESSKRSSEEERRRRRTRRRRERWERRENTRRRYRRR
78 79 A E H < S+ 0 0 78 158 72 EEEEEEERREEAREERKRRRRVKRKHHRRHRRRRERRRRRRSRLRRRRQRQQQQLQQNQQLIRQQHRQQQ
79 80 A D X + 0 0 32 158 7 DDDDDDDDDDADDDDDNDDDDDDDNDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDHDDDDDDDDDDDD
80 81 A P T 4 S+ 0 0 106 158 85 ISSCCCSPGSCAGCSRPVSSSKQSPCHPPHNKPPQPPGGSPNKPLLLLVPVVVVPVVKAVHPEVVVSVVV
81 82 A Q T >4 S+ 0 0 125 158 89 HHHYYHYHHFFFHHFHFHTSSTQVFNTITTSNEECEEVTSEENYTTTTVHVVVVCVVTVVHVAVVVMVVV
82 83 A L G >4 S+ 0 0 4 158 5 LLLLLLLLLLVLLLLLVLLLLLLLVLLLLLLVLLLLLLLLLLVLLLLLLLLLLLLLLLLLFLLLLLFLLL
83 84 A A G >< S+ 0 0 6 158 51 AAAAAAAAAAAAAAAAAAAYYYFYAAVYYVFYSSSSSAYFSAYSYYYYAYAAAAYAAAAASHHAAAAAAA
84 85 A S G X S+ 0 0 82 158 63 QGGEEEEREEKEDREDASYEECKEAEEASESSAATAAKSSATSESSSSDDDDDDTDDKGDESADDDEDDD
85 86 A K G < S+ 0 0 120 158 81 TTTIITTKKKKKHTKKKDKKKEQSKQQEEQKEVEEEVQEEVNETEEEEATAAAAEAANAAHEEAAARAAA
86 87 A M G < S+ 0 0 0 158 8 LLLLLLLMLLMILLLLLLLLLLLLLLLLLLLLLLLLLLVLLLLLLLLLMLMMMMLMMMMMLLLMMMLMMM
87 88 A G < + 0 0 30 156 30 GGGEEGGNGKEGAGKGGGGGGGGGGGGGGGGDGGNGGGGGGRNHGGGGGGGGGGQGGGGGGG GGGEGGG
88 89 A L 0 0 108 152 13 LLLLLLLLLLLLL LLLLFLLLLLLLL LLL LLLLLLLLLL LLLLLIIIIIIIIILIILL IIILIII
89 90 A H 0 0 234 28 55 QQ E E D E N D E
## ALIGNMENTS 141 - 157
SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....5....:....6....:....7....:....8....:....9....:....0....:....1
1 2 A A 0 0 148 117 46 G PA AP SP DAA
2 3 A D + 0 0 90 130 35 A NE DE GN DDD
3 4 A Q > + 0 0 102 133 49 Q EE KQ EEDKKK
4 5 A L H > S+ 0 0 56 136 81 K RK VQ RRIKKK
5 6 A L H 4 S+ 0 0 5 151 7 ILLLMMMLLLLLLLLLL
6 7 A R H >4 S+ 0 0 116 151 74 RNLRRLLEHNNKLFSLL
7 8 A K H >< S+ 0 0 151 152 66 KKNSKKKESKKKNKASS
8 9 A K T 3X S+ 0 0 66 152 79 GVIVGRRVVVVLVNLVV
9 10 A R H <> S+ 0 0 106 152 1 RRRRRRRRRRRRRRRRR
10 11 A R H <> S+ 0 0 173 152 83 LRRPLRRVTKKRSVRTT
11 12 A I H 4 S+ 0 0 43 153 88 AASDATTQEAAESICRR
12 13 A F H >X S+ 0 0 0 153 5 FIFFFFFIFIIFFFFLL
13 14 A I H 3< S+ 0 0 19 153 21 VIIIVIIVVIIAIIPVV
14 15 A H T 3< S+ 0 0 118 153 72 RDDDREEDINNDDNTDD
15 16 A S T <4 S+ 0 0 72 153 73 LGGHLRRDRGGNRNLGG
16 17 A V < - 0 0 5 156 52 SCIVSSSLVCCVILVLL
17 18 A G > - 0 0 34 157 63 KNSSKSSESNNSSSQNN
18 19 A A H > S+ 0 0 61 157 84 LPGNREEGGPPKGLSHH
19 20 A G H >> S+ 0 0 52 157 56 EAPPESSPPAAPPDLAA
20 21 A T H 3> S+ 0 0 21 157 54 TMVVTTTVVMMVVTNVV
21 22 A I H 3X S+ 0 0 2 158 23 LILLLVVILIILLVTII
22 23 A N H X>S+ 0 0 2 157 13 MLL.MMMLLLLLLLMLL
29 30 A L H ><5S+ 0 0 66 157 20 LRL.LQQRLQQLLLINN
30 31 A E H 3<5S+ 0 0 139 158 55 AEELAEEEQDDEEHGSS
31 32 A D H <<5S- 0 0 50 158 71 EKNQEIIKHKKQKAGDD
32 33 A E T <<5 + 0 0 158 158 68 RNKHRGGKTHHKKCEGG
33 34 A V < + 0 0 46 158 11 VVVCVVVVVVVVVVHVV
34 35 A I S S- 0 0 25 157 23 FLIRFIIL.LLLILFLL
35 36 A S >> - 0 0 55 158 32 NVTVNNNNIKKNTTSNN
36 37 A Q H 3> S+ 0 0 137 158 51 EDDIERRKNDDEDQQDD
37 38 A E H 3> S+ 0 0 157 158 52 GSASEGGGQYYGASDGG
38 39 A D H X> S+ 0 0 25 158 20 QEEDQEEEEEEEEEEEE
39 40 A M H 3X S+ 0 0 37 158 69 AVRAAAAVEVVYRLCVV
40 41 A N H 3X S+ 0 0 79 157 39 AEEEACCEMEEEEEEEE
41 42 A K H << S+ 0 0 89 158 78 DHEADEESEHHAEYREE
42 43 A V H >< S+ 0 0 14 158 25 IIADIIIISIILACVVV
43 44 A R H 3< S+ 0 0 169 158 80 LKNQLMMLVNNKNTTTT
44 45 A D T 3< S- 0 0 116 158 78 EEVIEEEEKKKEVEAEE
45 46 A E < - 0 0 109 158 59 SSMRSCCEVKKGMLIGG
46 47 A N - 0 0 84 155 32 NNPTNNNNINNS..NQQ
47 48 A D S S+ 0 0 115 157 76 DNNKDPPPANNTPTKSS
48 49 A T S >> S- 0 0 80 158 52 TTKPTTTSETTRNTTRR
49 50 A V H 3> S+ 0 0 35 156 82 RN.RRRRRRSSRRKATT
50 51 A M H 3> S+ 0 0 102 158 75 ARSAAAAGTRRGSSMRR
51 52 A D H <> S+ 0 0 45 158 9 DDDENDDDEDDDDDDDD
52 53 A K H X S+ 0 0 38 158 47 IRRKIKKKKRRKKKKKK
53 54 A A H X S+ 0 0 0 158 22 ACAAAAAAACCAAIAAA
54 55 A R H X S+ 0 0 106 157 8 RRRRRRRRRRRLRRRRR
55 56 A V H X S+ 0 0 3 158 70 AAFEARRKDDDEFFACC
56 57 A L H X S+ 0 0 4 158 9 LMVLLIILIMMLVLFLL
57 58 A I H X S+ 0 0 4 158 22 IIIIIIIVIIIIIVLVV
58 59 A D H X S+ 0 0 104 158 2 DDDDDDDDDDDDDDEDD
59 60 A L H X S+ 0 0 23 158 65 SSTSSSSSMSSITSFMM
60 61 A V H >< S+ 0 0 0 158 5 VVVVVVVVVVVVVCLVV
61 62 A T H >< S+ 0 0 39 158 81 TKRRSRRKLKKRRCSRR
62 63 A G H 3< S+ 0 0 56 158 60 KKNKKKKNRKKKNKKKK
63 64 A K T << S- 0 0 82 158 4 QKKKKKKKKKKKKKKKK
64 65 A G X> - 0 0 25 158 1 GGGGGGGGGGGGGGSGG
65 66 A P H 3> S+ 0 0 67 157 68 DDEADNNSTEEQENNSS
66 67 A K H 3> S+ 0 0 155 158 83 VDREVCCDEYYKRVERR
67 68 A S H <> S+ 0 0 4 158 15 APAATAAASSSAAAAAA
68 69 A C H X S+ 0 0 28 158 32 CSTSCCCSCSSSTSFSS
69 70 A C H X S+ 0 0 52 158 73 SNSSSTTKSNNESNTEE
70 71 A K H X S+ 0 0 81 158 68 LIQRLVVIRIIKQICKK
71 72 A F H X S+ 0 0 0 158 60 FLMMFFFFMLLFMFFLL
72 73 A I H X S+ 0 0 29 158 36 ALITAVVIILLIILQLL
73 74 A K H X S+ 0 0 120 158 77 GEESGRRANEEQEYDSS
74 75 A H H X S+ 0 0 23 158 86 ASSAAEEQLSSSSGARR
75 76 A L H X S+ 0 0 1 158 21 ILLLIIILLLLILLLLL
76 77 A C H < S+ 0 0 45 158 83 AVCCAMMKGVVQCYSQQ
77 78 A E H < S+ 0 0 143 158 68 RKESRTTIEKKYEEQEE
78 79 A E H < S+ 0 0 78 158 72 QNLNQMMRLNNRLLERR
79 80 A D X + 0 0 32 158 7 DHDDDDDDDHHDDDQDD
80 81 A P T 4 S+ 0 0 106 158 85 VKFPVQQEPKKSFNPGG
81 82 A Q T >4 S+ 0 0 125 158 89 VTFYIEEHCTTMFNFSS
82 83 A L G >4 S+ 0 0 4 158 5 LLFLLLLFLLLFFVLLL
83 84 A A G >< S+ 0 0 6 158 51 AACSVAAYYAAACFAHH
84 85 A S G X S+ 0 0 82 158 63 DKESGVVNTEEEESNGG
85 86 A K G < S+ 0 0 120 158 81 ASHEALLKESSRHMIQQ
86 87 A M G < S+ 0 0 0 158 8 MLLLMMMLLLLLLILLL
87 88 A G < + 0 0 30 156 30 GGGGGEEKQGGEGS EE
88 89 A L 0 0 108 152 13 ILLLLLLLILLLLF LL
89 90 A H 0 0 234 28 55 H EE NHHE K DD
## SEQUENCE PROFILE AND ENTROPY
SeqNo PDBNo V L I M F W Y G A P S T C H R K Q E N D NOCC NDEL NINS ENTROPY RELENT WEIGHT
1 2 A 0 0 0 0 0 0 0 14 56 12 2 15 0 0 0 0 0 0 0 1 117 0 0 1.247 41 0.54
2 3 A 0 0 0 0 0 0 0 2 16 0 0 0 0 1 0 1 0 3 2 75 130 0 0 0.841 28 0.64
3 4 A 1 0 1 2 0 0 0 0 1 0 0 0 0 0 2 59 27 5 2 2 133 0 0 1.181 39 0.51
4 5 A 37 7 14 1 1 0 0 0 0 0 0 2 0 1 4 7 5 19 0 2 136 0 0 1.898 63 0.18
5 6 A 0 87 5 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 151 0 0 0.480 16 0.92
6 7 A 0 8 1 1 5 0 0 2 3 0 2 1 0 3 22 45 1 2 2 1 151 0 0 1.824 60 0.25
7 8 A 0 0 0 0 0 0 0 5 5 0 7 1 0 0 9 26 2 38 3 6 152 0 0 1.774 59 0.33
8 9 A 22 5 4 0 0 0 0 11 1 0 0 0 0 0 4 53 0 0 1 0 152 0 0 1.381 46 0.20
9 10 A 0 0 0 0 0 1 0 0 0 0 0 0 0 0 98 1 0 0 0 0 152 0 0 0.110 3 0.98
10 11 A 2 13 2 1 0 1 1 2 3 3 7 7 1 0 19 38 0 0 1 1 152 0 0 2.005 66 0.17
11 12 A 5 33 5 3 3 0 0 0 11 0 1 1 1 0 6 8 11 5 1 6 153 0 0 2.223 74 0.12
12 13 A 0 4 3 0 93 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 153 0 0 0.308 10 0.94
13 14 A 48 0 48 0 0 0 0 0 3 1 0 0 0 0 0 0 0 0 0 0 153 0 0 0.849 28 0.78
14 15 A 0 0 1 0 0 0 1 2 1 0 2 2 2 14 31 1 6 17 10 10 153 0 0 2.055 68 0.27
15 16 A 0 10 0 1 0 0 0 7 1 0 58 0 0 1 8 11 1 0 2 1 153 0 0 1.439 48 0.27
16 17 A 61 5 2 13 0 0 0 0 3 0 12 2 3 0 0 0 0 0 0 0 156 0 0 1.314 43 0.47
17 18 A 0 0 0 0 0 0 0 34 1 0 33 4 0 0 2 11 1 2 7 6 157 0 0 1.687 56 0.37
18 19 A 2 10 1 7 0 0 0 4 8 3 3 10 0 2 4 18 0 27 1 1 157 0 0 2.243 74 0.16
19 20 A 1 1 0 0 0 0 0 55 9 10 3 1 0 1 1 0 3 11 0 6 157 0 0 1.562 52 0.43
20 21 A 17 7 4 6 0 0 0 0 1 0 0 65 0 0 0 0 0 0 1 0 157 0 0 1.122 37 0.46
21 22 A 6 22 70 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 158 0 0 0.848 28 0.76
22 23 A 1 0 0 0 0 0 0 0 0 0 9 0 0 1 3 8 11 0 63 3 158 0 0 1.271 42 0.47
23 24 A 0 2 0 0 0 0 0 52 5 0 6 0 0 0 1 3 15 2 12 4 158 0 0 1.590 53 0.38
24 25 A 0 97 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158 0 0 0.140 4 0.96
25 26 A 1 84 12 2 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 158 0 0 0.600 20 0.83
26 27 A 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0 0 1 97 158 0 0 0.174 5 0.95
27 28 A 0 1 0 0 0 0 1 1 1 0 0 1 4 0 3 3 0 56 1 29 158 1 0 1.264 42 0.55
28 29 A 1 78 6 14 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 157 0 0 0.706 23 0.87
29 30 A 1 84 1 0 8 0 0 0 0 0 0 0 0 0 1 0 3 0 1 0 157 0 0 0.661 22 0.79
30 31 A 0 2 0 2 0 0 0 1 16 0 1 0 0 2 0 2 20 50 0 4 158 0 0 1.488 49 0.45
31 32 A 1 1 2 1 0 0 0 1 1 0 1 19 0 4 1 32 5 13 1 19 158 0 0 1.933 64 0.29
32 33 A 0 0 0 1 0 0 0 13 1 0 1 1 3 3 51 13 3 5 4 0 158 0 0 1.689 56 0.31
33 34 A 86 1 11 1 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 158 1 0 0.520 17 0.89
34 35 A 6 68 13 0 13 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 157 0 0 0.982 32 0.76
35 36 A 1 0 1 0 0 0 0 1 0 0 13 3 0 0 0 1 0 0 80 0 158 0 0 0.733 24 0.67
36 37 A 0 3 1 0 0 0 1 1 0 0 0 0 0 3 2 8 44 22 1 15 158 0 0 1.612 53 0.48
37 38 A 0 0 0 4 0 0 1 25 2 0 4 0 0 0 0 0 2 61 0 1 158 0 0 1.151 38 0.48
38 39 A 0 1 0 0 0 0 0 0 0 0 0 0 0 3 0 1 7 83 0 6 158 0 0 0.685 22 0.80
39 40 A 11 1 5 53 0 0 1 0 13 0 1 2 1 0 4 8 0 1 0 0 158 1 0 1.626 54 0.31
40 41 A 1 0 0 1 0 0 0 0 11 0 0 0 1 0 0 0 1 67 4 14 157 0 0 1.099 36 0.61
41 42 A 0 0 9 0 0 0 1 0 4 0 13 3 0 2 9 36 0 10 0 12 158 0 0 1.925 64 0.21
42 43 A 54 3 39 0 0 0 0 0 2 0 1 0 1 0 0 0 0 0 0 1 158 0 0 0.986 32 0.75
43 44 A 1 17 3 1 1 0 0 0 1 0 0 6 1 0 27 34 4 1 3 0 158 0 0 1.779 59 0.19
44 45 A 3 3 1 0 0 0 1 1 3 0 1 0 13 2 20 3 0 37 1 13 158 0 0 1.897 63 0.21
45 46 A 1 1 2 1 0 0 0 8 6 0 12 0 2 0 2 2 1 61 1 1 158 3 0 1.491 49 0.40
46 47 A 0 0 1 1 0 0 2 0 1 1 5 1 0 5 1 1 1 0 82 0 155 0 0 0.850 28 0.68
47 48 A 5 0 5 1 0 0 1 1 34 10 6 3 0 1 1 4 1 1 6 20 157 0 0 2.099 70 0.23
48 49 A 4 1 4 1 0 0 0 0 3 3 5 68 0 0 6 1 0 1 4 0 158 2 0 1.315 43 0.47
49 50 A 44 1 3 1 0 0 0 0 4 1 1 8 0 0 31 3 0 0 1 3 156 0 0 1.579 52 0.18
50 51 A 0 0 0 51 0 0 0 4 27 0 6 4 0 0 6 1 0 1 1 0 158 0 0 1.391 46 0.25
51 52 A 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 1 0 5 1 91 158 0 0 0.410 13 0.90
52 53 A 0 0 11 1 0 0 0 0 1 0 0 0 0 0 9 70 8 0 0 0 158 0 0 0.996 33 0.52
53 54 A 0 0 1 0 0 0 0 0 84 0 0 13 3 0 1 0 0 0 0 0 158 1 0 0.569 18 0.77
54 55 A 0 3 0 0 0 0 0 0 0 0 0 0 0 0 96 0 1 0 0 0 157 0 0 0.187 6 0.91
55 56 A 12 0 0 0 2 0 0 0 54 0 3 0 7 1 6 1 1 2 1 11 158 0 0 1.607 53 0.30
56 57 A 6 86 3 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158 0 0 0.567 18 0.90
57 58 A 4 15 75 1 1 0 0 0 0 0 0 1 4 0 0 0 0 0 0 0 158 0 0 0.862 28 0.78
58 59 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 97 158 0 0 0.136 4 0.97
59 60 A 1 6 6 4 1 0 2 1 6 0 58 9 1 3 0 1 0 0 1 1 158 0 0 1.638 54 0.34
60 61 A 94 3 3 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 158 0 0 0.296 9 0.95
61 62 A 1 7 42 0 1 0 0 0 0 0 3 18 1 0 15 13 0 0 0 0 158 0 0 1.605 53 0.19
62 63 A 0 3 0 0 0 1 0 6 1 13 1 0 1 0 39 31 1 0 4 0 158 0 0 1.609 53 0.40
63 64 A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 97 3 0 0 0 158 0 0 0.118 3 0.96
64 65 A 0 0 0 0 0 0 0 99 0 0 1 0 0 0 0 0 0 0 0 0 158 1 0 0.038 1 0.99
65 66 A 1 0 0 0 0 0 0 0 25 29 7 2 0 1 0 0 1 7 4 22 157 0 0 1.770 59 0.32
66 67 A 15 2 0 1 0 1 2 0 1 4 0 3 1 0 20 14 25 7 3 3 158 0 0 2.153 71 0.16
67 68 A 0 0 0 0 0 0 0 1 90 1 7 1 0 0 0 0 0 0 0 0 158 0 0 0.424 14 0.85
68 69 A 0 0 0 0 1 0 0 0 1 0 42 1 55 0 0 0 0 0 0 0 158 0 0 0.812 27 0.68
69 70 A 0 1 0 0 0 1 0 0 1 0 18 3 3 5 6 6 46 8 3 0 158 0 0 1.779 59 0.27
70 71 A 7 12 49 3 0 0 1 0 0 0 1 0 2 1 3 20 1 1 0 0 158 0 0 1.573 52 0.31
71 72 A 0 12 0 11 49 0 0 0 0 0 0 0 28 0 0 0 0 0 0 0 158 0 0 1.203 40 0.40
72 73 A 2 7 78 0 0 0 0 0 11 0 0 2 0 0 0 0 1 0 0 0 158 0 0 0.803 26 0.63
73 74 A 1 0 2 0 0 0 1 14 8 0 11 27 3 1 3 7 2 6 4 9 158 0 0 2.291 76 0.23
74 75 A 0 1 0 0 2 0 28 1 13 0 13 0 1 28 4 0 1 1 4 1 158 0 0 1.875 62 0.13
75 76 A 1 27 73 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158 0 0 0.615 20 0.79
76 77 A 3 0 1 1 0 1 1 2 11 0 1 0 56 0 4 5 11 3 0 0 158 0 0 1.601 53 0.17
77 78 A 0 0 1 0 0 1 1 1 1 0 6 3 1 1 14 9 1 51 7 1 158 0 0 1.722 57 0.31
78 79 A 1 4 3 1 0 0 0 0 1 0 1 0 0 3 22 2 10 43 4 6 158 0 0 1.791 59 0.27
79 80 A 0 0 0 0 0 0 0 0 1 0 0 0 0 3 0 0 1 0 1 95 158 0 0 0.262 8 0.92
80 81 A 11 3 3 0 1 0 0 4 2 18 23 3 10 5 6 5 3 1 3 0 158 0 0 2.384 79 0.15
81 82 A 12 0 1 1 6 0 20 0 1 1 4 9 2 30 0 0 5 5 3 0 158 0 0 2.099 70 0.11
82 83 A 4 92 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158 0 0 0.321 10 0.94
83 84 A 3 0 0 0 3 0 11 0 75 0 6 0 1 3 0 0 0 0 0 0 158 0 0 0.956 31 0.48
84 85 A 1 0 0 0 0 0 1 27 7 0 12 3 1 0 2 3 4 25 1 13 158 0 0 1.994 66 0.37
85 86 A 5 2 6 1 0 0 0 0 11 0 3 32 0 3 2 18 4 12 1 1 158 0 0 2.090 69 0.19
86 87 A 1 76 1 22 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 158 0 0 0.659 21 0.92
87 88 A 0 0 0 0 0 0 0 79 1 0 1 0 0 1 2 2 3 10 2 1 156 0 0 0.880 29 0.70
88 89 A 0 86 13 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152 0 0 0.445 14 0.86
89 90 A 0 0 0 0 0 0 0 0 0 0 0 0 0 29 4 4 14 29 7 14 28 0 0 1.698 56 0.44
## INSERTION LIST
AliNo IPOS JPOS Len Sequence
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